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Dr. Isma has recently joined the Department of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM). She graduated Bachelor of Biomedical Sciences (Honours) from UKM in 2006 and then worked in the Ministry of Health, Malaysia (2008-2013). She was conferred a PhD (Anatomy) from the National University of Ireland (NUI), Galway, in 2017. She did her post-doctorate research in SFI Research Centre for Medical Devices (CÚRAM), NUI Galway (2017-2020), and the Department of Orthopaedics and Traumatology UKM (2021). Dr Isma has expertise in intervertebral disc and biomaterial research. Her work focuses on degenerative disc disease, specifically to modulate inflammatory pain, extracellular matrix regulation, disc microstructure, and molecular, proteome and glycome profiling in disc degeneration using a biomaterial approach. Dr Isma has been involved in disease modelling to establish a pre-clinical model of pain induced by disc injury. She is also developing a bioengineered hydrogel to support stem cell transplantation for disc regeneration targeting inflammatory pain. She plans to advance her research towards a patient-specific regenerative therapy using precision medicine and biomaterial-based tissue engineering. Her major achievements include the patent filed of the technology to promote disc regeneration targeting pain and the recipient of prestigious awards, including Julia Polak European Doctorate Award from the European Society for Biomaterials and First Prize Young Researcher Award from AO Spine. She has authored/co-authored numerous publications in high-impact journals, including Science Advances, PNAS, Biomaterials, and Advanced Science. Dr Isma is also a reviewer for peer-reviewed journals and actively presented her work at tier-one international conferences includes World Biomaterials Congress, World Forum for Spine Research, and Orthopaedic Research Society.
Doktor Falsafah , NATIONAL UNIVERSITY OF IRELAND , 2017 |
Sarjana Muda dengan Kepujian , UNIVERSITI KEBANGSAAN MALAYSIA , 2006 |
CLINICAL AND HEALTH SCIENCES - BASIC MEDICAL SCIENCES (Anatomy; Basic Spine Research) |
PURE AND APPLIED SCIENCES - MATERIALS SCIENCE (Biomaterials; Tissue Engineering) |
Isma Liza Mohd Isa, Seong Lin Teoh, Nurul Huda Mohd Nor, Sabarul Afian Mokhtar. (2023). Discogenic Low Back Pain: Anatomy, Pathophysiology And Treatments Of Intervertebral Disc Degeneration. - International Journal Of Molecular Sciences. 1-16. |
Isma Liza Mohd Isa, Sabarul Afian Mokhtar, Sunny A. Abbah, Mh Busra Fauzi, Aiden Devitt, And Abhay Pandit. (2022). Intervertebral Disc Degeneration: Biomaterials And Tissue Engineering Strategies Toward Precision Medicine. - Advanced Healthcare Materials. 1-29. |
Nur Izzah Md Fadilah, Isma Liza Mohd Isa , Wan Safwani Wan Kamarul Zaman, Yasuhiko Tabata And Mh Busra Fauzi. (2022). The Effect Of Nanoparticle-incorporated Natural-based Biomaterials Towards Cells On Activated Pathways: A Systematic Review. - Polymers. 1-22. |
Masahiro Inoue, Isma Liza Mohd Isa, Sumihisa Orita, Miyako Suzuki-narita, Kazuhide Inage, Yasuhiro Shiga, Masaki Norimoto, Tomotaka Umimura, Takayuki Sakai, Yawara Eguchi, Atsuya Watanabe, Yasuchika Aoki, Abhay Pandit,and Seiji Ohtori. (2021). An Injectable Hyaluronic Acid Hydrogel Promotes Intervertebral Disc Repair In A Rabbit Model. - Spine. E810-E816. |
Isma Liza Mohd Isa, Seong Lin Teoh, Nurul Huda Mohd Nor, Sabarul Afian Mokhtar. (2023). Discogenic Low Back Pain: Anatomy, Pathophysiology And Treatments Of Intervertebral Disc Degeneration. - International Journal Of Molecular Sciences. 1-16. |
Isma Liza Mohd Isa, Sabarul Afian Mokhtar, Sunny A. Abbah, Mh Busra Fauzi, Aiden Devitt, And Abhay Pandit. (2022). Intervertebral Disc Degeneration: Biomaterials And Tissue Engineering Strategies Toward Precision Medicine. - Advanced Healthcare Materials. 1-29. |
Nur Izzah Md Fadilah, Isma Liza Mohd Isa , Wan Safwani Wan Kamarul Zaman, Yasuhiko Tabata And Mh Busra Fauzi. (2022). The Effect Of Nanoparticle-incorporated Natural-based Biomaterials Towards Cells On Activated Pathways: A Systematic Review. - Polymers. 1-22. |
Isma Liza Mohd Isa, Mh Busra Fauzi, Nurul Huda Mohd Yusoff, Natasya Nadia Sahruddin, Shaiful Ridzwan Sapri, Mohd Hanafi Damanhuri, Sabarul Afian Mokhtar. (2022). Hyaluronic Acid/collagen Hydrogel To Mimic Nucleus Pulposus Microenvironment: An Implication For The Stem Cell Transplantation In Intervertebral Disc. - Malaysian Journal Of Medicine And Health Sciences. 2. |
Masahiro Inoue, Isma Liza Mohd Isa, Sumihisa Orita, Miyako Suzuki-narita, Kazuhide Inage, Yasuhiro Shiga, Masaki Norimoto, Tomotaka Umimura, Takayuki Sakai, Yawara Eguchi, Atsuya Watanabe, Yasuchika Aoki, Abhay Pandit,and Seiji Ohtori. (2021). An Injectable Hyaluronic Acid Hydrogel Promotes Intervertebral Disc Repair In A Rabbit Model. - Spine. E810-E816. |
Biocompatibility and immuno-modulatory effect of the hyaluronic acid/collagen-based hydrogel for intervertebral disc regeneration , Ketua Projek , 01-10-2022 sehingga 30-09-2024 , Antarabangsa |
Modulation of Inflammatory Pain in Intervertebral Disc Degeneration using 3D Hydrogel Encapsulated with Mesenchymal Stem Cells , Ketua Projek , 01-09-2022 sehingga 31-08-2025 , Kebangsaan |
Modulation of Inflammatory Pain in Intervertebral Disc Degeneration using 3D Hydrogel Encapsulated with Mesenchymal Stem Cells , Ketua Projek , 01-09-2022 sehingga 31-08-2025 , Kebangsaan |
The Development Of Hyaluronic Acid/Collagen Hydrogel Towards Nucleus Pulposus Niche , Ketua Projek , 24-02-2022 sehingga 23-02-2023 , Universiti |
Regeneration of the degenerative intervertebral disc in Sprague Dawley rats , Penyelidik Bersama , 12-04-2021 sehingga 11-04-2022 , Universiti |
KARTHINI DEVI A/P RAJAN, Sarjana |
RAED HAMZAH MOHAMMED, Doktor Falsafah |
Micro-RNA-340-mediated Downregulation of PHD3 Accelerates Intervertebral Disc Degeneration through Enchancing Beta-catenin Expression , 15-10-2021 sehingga 22-10-2021 , Antarabangsa |
American Association for The Advancement of Science , 29-05-2021 sehingga 31-05-2022 , Antarabangsa |
AO Spine , 24-11-2020 sehingga 11-12-2021 , Antarabangsa |
International Association For The Study Of Pain , 11-02-2021 sehingga 11-02-2022 , Antarabangsa |
Tissue Engineering and Regenerative Medicine Society of Malaysia , 11-02-2021 sehingga 11-02-2022 , Kebangsaan |
Tissue Engineering and Regenerative Medicine International Society , 25-05-2021 sehingga 25-05-2022 , Antarabangsa |
Award for Orthoregeneration Network/Orthopaedic Research Society (ON/ORS) Education Grant , 04-01-2022 sehingga 01-01-1970 , Antarabangsa |
Gold Medal of the International Innovation Award 2022 , 25-03-2022 sehingga 01-01-1970 , Kebangsaan |
AJK Keahlian (Wakil Batch) Persatuan Alumni Sains Bioperubatan UKM 2021-2022 , 01-09-2021 sehingga 01-09-2022 , Kebangsaan |
Orthopaedic Research Society , 01-01-2022 sehingga 01-12-2022 , Antarabangsa |
Malaysian Anatomy Association , 21-03-2022 sehingga 02-01-4337 , Kebangsaan |
Sensory nerve maintains intervertebral disc extracellular matrix homeostasis via CGRP/CHSY1 axis , 13-06-2022 sehingga 19-06-2022 , Antarabangsa |
Dr Nahdia Afiifah Abdul Jalil , 24-06-2022 sehingga 25-06-2022 , Antarabangsa |
Open Education Grant , 24-08-2022 sehingga 01-01-1970 , Antarabangsa |
Tissue Engineering and Regenerative Medicine Society of Malaysia (TESMA) SEMINAR SERIES 2/2022 , 14-08-2022 sehingga 14-08-2022 , Kebangsaan |
Emerging Investigator Award for Health , 23-11-2022 sehingga 01-01-1970 , Antarabangsa |
Honorary Research Senior Lecturer , 01-04-2023 sehingga 01-01-1970 , Antarabangsa |
Honorary Research Senior Lecturer , 01-04-2023 sehingga 31-03-2027 , Antarabangsa |
Malaysian Orthopaedic Association , 14-11-2022 sehingga 14-11-2023 , Kebangsaan |
BENGKEL ANATOMY INTENSIVE COURSE 4.0 , 01-09-2022 sehingga 30-11-2022 , Pusat Pengajian / Jabatan / Pusat Penyelidikan / Unit |
JAWATANKUASA MINGGU APRESIASI WATAN (MAW) SESI 2022/2023 , 10-10-2022 sehingga 10-10-2022 , Universiti |
JAWATANKUASA PENAKSIR SOALAN DALAM PENYEDIAAN SOALAN PEPERIKSAAN SARJANA MUDA KEJURURAWATAN , 03-10-2022 sehingga 24-03-2023 , Fakulti / Institut / Pusat Perkhidmatan |
JAWATANKUASA PENAKSIRAN SOALAN MODUL MUSKULOSKELETAL (FFFF1424) SESI 2021/2022 , 02-05-2022 sehingga 30-12-2022 , Pusat Pengajian / Jabatan / Pusat Penyelidikan / Unit |
Lantikan Sebagai Penemuduga Sesi Pemilihan Pelajar Program Doktor Perubatan Fakulti Perubatan UKM Bagi Sesi Akademik 2022-2023 , 05-07-2022 sehingga 07-07-2022 , Fakulti / Institut / Pusat Perkhidmatan |
PENYELIA MODUL KAJIAN KHUSUS (SSM) FF4812 DAN FF4822 TAHUN 4 SESI 2022/2023 , 19-09-2022 sehingga 09-07-2023 , Fakulti / Institut / Pusat Perkhidmatan |
PROJEK KHIDMAT KEMASYARAKATAN LAWATAN AKADEMIK PELAJAR ASASIpintar PUSAT GENIUS NEGARA@PINTAR NEGARA UKM KE MUZIUM ANATOMI , 19-12-2022 sehingga 19-12-2022 , Pusat Pengajian / Jabatan / Pusat Penyelidikan / Unit |
Urusetia Minggu Apresiasi Watan (Maw) Sesi 2022/2023 Universiti Kebangsaan Malaysia , 08-10-2022 sehingga 12-10-2022 , Universiti |