sze ping wee, khye er loh, kok wai lam, intan safinar ismail. (2023). a study of the interaction between xanthine oxidase and its inhibitors from chrysanthemum morifolium using computational simulation and multispectroscopic methods. - metabolites. 1-19. |
vincentsia vienna vanessa, soek sin teh, kok wai lam, siau hui mah. (2023). synthesis of 1-hydroxy-3-o-substituted xanthone derivatives and their structure-activity relationship on acetylcholinesterase inhibitory effect. - natural product research. 2849-2861. |
rajibul islam, mock phooi yan, khor poh yen, nurulfazlina edayah rasol, chan kok meng, lam kok wai. (2023). synthesis and biological evaluation of chromone derivatives against triple-negative breast cancer cells. - medicinal chemistry research. 884-898. |
anis nadyra zifruddin, mohamad ariff mohamad yusoff, nur syatila abd ghani, nor azlan nor muhammad, kok wai lam, maizom hassan. (2023). ensemble-based, high-throughput virtual screening of potential inhibitor targeting putative farnesol dehydrogenase of metisa plana (lepidoptera: psychidae). - computational biology and chemistry. 1-19. |
mahasakthy-vijeyasri satyaveanthan, chyan leong ng, alias awang, kok wai lam, maizom hassan. (2023). isolation, purification and biochemical characterization of conopomorpha cramerella farnesol dehydrogenase. - insect molecular biology. 143-159. |
nur syahirah che razali, kok wai lam, nor fadilah rajab, a. rahman a. jamal, nurul farahana kamaluddin, kok meng chan. (2022). curcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in ln-18 human glioblastoma cells. - scientific reports. 1-17. |
ogochukwu ngozi nwaefulu, nizar a. alshar'i, josephine omonkhelin owolabi, sreenivasa rao sagineedu, lim chee woei, lam kok wai, mohammad kaisarul islam, sivaraman jayanthi, johnson stanslas. (2022). the impact of cycleanine in cancer research a computational study. - journal of molecular modeling. 1-13. |
yu xian goh, juriyati jalil, kok wai lam, khairana husain, chandini menon premakumar. (2022). genistein: a review on its anti-inflammatory properties. - frontiers in pharmacology. 1-23. |
nor nadirah abdullah, syahrul imran, kok wai lam, nor hadiani ismail. (2022). computational screening of styryl lactone compounds isolated from goniothalamus species to identify potential inhibitors for dengue virus. - journal of computational biophysics and chemistry. 821-843. |
nur zahirah abd rani, kok wai lam, juriyati jalil, hazni falina mohamad, mohd shukri mat ali, khairana husain. (2021). mechanistic studies of the antiallergic activity of phyllanthus amarus schum. & thonn. and its compounds. - molecules. 1-16. |
mohd asyraf shamsuddi, amatul hamizah ali, nur hanis zakaria, mohd fazli mohammat, ahmad sazali hamzah, zurina shaameri, kok wai lam, wun fui mark-lee, hani kartini agustar, mohd ridzuan mohd abd razak, jalifah latip & nurul izzaty hassan. (2021). synthesis, molecular docking, and antimalarial activity of hybrid 4-aminoquinoline-pyrano[2,3-c]pyrazole derivatives. - pharmaceuticals. 1-17. |
khor poh yen, johnson stanslas, tianshu zhang, hongyuan li, xiaohui wang, chan kok meng, lam kok wai. (2021). synthesis of small molecules targeting paclitaxel-induced myd88 expression in triple-negative breast cancer cell lines. - bioorganic and medicinal chemistry. 1-12. |
zi han loh, huey chong kwong, kok wai lam, soek sin teh, gwendoline cheng lian ee, ching kheng quah, anthony siong hock ho, siau hui mah. (2021). new 3-o-substituted xanthone derivatives as promising acetylcholinesterase inhibitors. - journal of enzyme inhibition and medicinal chemistry. 627-639. |
nuraziemah ahmad, chua eng wee, lam kok wai, noraziah mohamad zin, fazren azmi. (2021). biomimetic amphiphilic chitosan nanoparticles: synthesis, characterization and antimicrobial activity. - carbohydrate polymers. 1-8. |
siti munirah mohd faudzi, leong sze wei, faruk a. auwal, faridah abas, lam kok wai, syahida ahmad, tham chau ling, khozirah shaari, nordin h. lajis, bohari m. yamin. (2021). in silico studies, nitric oxide, and cholinesterases inhibition activities of pyrazole and pyrazoline analogs of diarylpentanoids. - archiv der pharmazie. 1-13. |
mahasakthy-vijeyasri satyaveanthan, saidi-adha suhaimi, chyan leong ng, noor-dina muhd-noor, alias awang, kok wai lam, maizom hassan. (2021). purification, biochemical characterisation and bioinformatic analysis of recombinant farnesol dehydrogenase from theobroma cacao. - plant physiology and biochemistry. 143-155. |
nur hanis zakaria, lam kok wai, nurul izzaty hassan. (2020). molecular docking study of the interactions between plasmodium falciparum lactate dehydrogenase and 4-aminoquinoline hybrids. - sains malaysiana. 8-11. |
julop franci, kok wai lam, tse seng chuah, thye san cha. (2020). genetic diversity and in silico evidence of target-site mutation in the epsps gene in endowing glyphosate resistance in eleusine indica (l.) from malaysia. - pesticide biochemistry and physiology. 1-10. |
rajibul islam, kok wai lam. (2020). recent progress in small molecule agents for the targeted therapy of triple-negative breast cancer. - european journal of medicinal chemistry. 1-21. |
akm moyeenul huq, lam kok wai, kamal rullah, mohd fadhlizil fasihi mohd alwi, johnson stanslas, jamia azdina jamal. (2019). oestrogenic activity of mimosine on mcf-7 breast cancer cell line through the er alpha-mediated pathway. - chemical biology and drug design. 222-231. |
nur zahirah abd rani, endang kumolosasi, malina jasamai, jamia azdina jamal, lam kok wai, khairana husain. (2019). in vitro anti-allergic activity of moringa oleifera lam. extracts and their isolated compounds. - bmc complementary & alternative medicine. 1-16. |
khor poh yen, mohd fadhlizil fasihi mohd aluwi, kamal rullah, lam kok wai. (2019). insights on the synthesis of asymmetric curcumin derivatives and their biological activities. - european journal of medicinal chemistry. 1-21. |
kamal rullah, mohd fadhlizil fasihi mohd aluwi, bohari m. yamin, joon ching juan and lam kok wai. (2019). palladium-catalysed cross-coupling reactions for the synthesis of chalcones. - asian journal of organic chemistry. 1174-1193. |
mohd fadhlizil fasihi mohd aluwi, kamal rullah, andreas koeberle, oliver werz, nur sakinah abdul razak, leong sze wei, faridah abas, nor hadiani ismail, ibrahim jantan, lam kok wai. (2019). design and synthesis of a novel mpges-1 lead inhibitor guided by 3d-qsar comfa. - journal of molecular structure. 844-850. |
ng chean hui, kamal rullah, faridah abas, lam kok wai, intan safinar ismail, fadzureena jamaludin and khozirah shaari. (2018). hits-to-lead optimization of the natural compound 2,4,6-trihydroxy-3-geranyl-acetophenone (thga) as a potent lox inhibitor: synthesis, structure-activity relationship (sar) study, and computational as. - molecules. . |
sze wei leong, faridah abas, kok wai lam, khatijah yusoff. (2018). in vitro and in silico evaluations of diarylpentanoid series as a-glucosidase inhibitor. - bioorganic and medicinal chemistry letters. 302-309. |
mohd hanif zulfakar, chan lee mei, khurram rehman, lam kok wai, charles m. heard. (2018). coenzyme q10-loaded fish oil-based bigel system: probing the delivery across porcine skin and possible interaction with fish oil fatty acids. - aaps pharm scitech. 1116-1123. |
siti nor aini harun, daud ahmad israf, chau ling tham, kok wai lam, manraj singh cheema and nur fariesha md hashim. (2018). the molecular targets and anti-invasive effects of 2,6-bis-(4-hydroxyl-3methoxybenzylidine) cyclohexanone or bhmc in mda-mb-231 human breast cancer cells. - molecules. . |
nor nadirah abdullah, kamal rullah, lam kok wai and malina jasamai. (2018). kajian dok molekul mengenai interaksi di antara rna-bergantung rna polimerase virus denggi dan analog nukleosida. - sains malaysiana. 517-522. |
radhakrishnan, n., lam, k. w. and norhaizan, m. e.. (2017). molecular docking analysis of carica papaya linn constituents as antiviral agent. - international food research journal. 1819-1825. |
a.k.m. moyeenul huq, kamal rullah, m.f.f.m.aluwi, lam kok wai, johnson stanslas, jamia azdina jamal. (2017). phyto-oestrogenic property of mimosine: a phenylalanine alkaloid. - biochemical pharmacology. 114. |
mohd fadhlizil fasihi mohd aluwi, kamal rullah, md. areeful haque, bohari m. yamin, waqas ahmad, muhammad wahab amjad, sze wei leong, nurul amira fahmizar, juriyati jalil, faridah abas, nor hadiani ismail, ibrahim jantan, kok wai lam. (2017). suppression of pge2 production via disruption of mapk phosphorylation by unsymmetrical dicarbonyl curcumin derivatives. - medicinal chemistry research. 1-13. |
radhakrishnan narayanaswamy, lam kok wai, norhaizan mohd esa. (2017). molecular docking analysis of phytic acid and 4-hydroxyisoleucine as cyclooxygenase-2, microsomal prostaglandin e synthase-2, tyrosinase, human neutrophil elastase, matrix metalloproteinase-2 and -9,. - pharmacognosy magazine. 512-518. |
ling l. chia, ibrahim jantan, kien h. chua, kok w. lam, kamal rullah and mohd f. m. aluwi. (2016). effects of tocotrienols on insulin secretion-associated genes expression of rat pancreatic islets in a dynamic culture. - frontiers in pharmacology. 1-17. |
mohd shakrie palan abdullah, mohamed ibrahim noordin, syed ibrahim mohd ismail, shaik nyamathulla, malina jasamai, lam kok wai, nur murnisa mustapha & ahmad fuad shamsuddin. (2016). physicochemical evaluation and spectroscopic characterisation of gelatine from shank and toes of gallus gallus domesticus. - sains malaysiana. 435-449. |
sze wei leong, faridah abas, kok wai lam, khozirah shaari, nordin h. lajis. (2016). 2-benzoyl-6-benzylidenecyclohexanone analogs as potent dual inhibitors of acetylcholinesterase and butyrylcholinesterase. - bioorganic and medicinal chemistry. 3742-3751. |
mohd fadhlizil fasihi mohd aluwi, kamal rullah, tan huan huan, chan kok meng, tan si jie, leong sze wei, ahmad hasnan mansor, bohari m. yamin and lam kok wai. (2016). synthesis and effects of oxadiazole derivatives on tyrosinase activity and human sk-mel-28 malignant melanoma cells. - rsc advances. 72177-72184. |
mohd fadhlizil fasihi, kamal rullah, bohari m. yamin, sze wei leong, mohd nazri , sock jin lim, siti munirah, juriyati jalil, faridah abas, norsyahida, nor hadiani, ibrahim jantan, kok wai lam. (2016). synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin e2 production in lps-induced murine and human macrophages cell lines. - bioorganic & medicinal chemistry letters. 2531-2538. |
khurram rehman, mohd fadhlizil fasihi mohd aluwi, kamal rullah, lam kok wai, mohd cairul iqbal mohd amin, mohd hanif zulfakar. (2015). probing the effects of fish oil on the delivery and inflammation-inducing potential of imiquimod. - international journal of pharmaceutics. 131-141. |
narayanaswamy r., kok wai l., ismail i.s.. (2015). in silico analysis of selected honey constituents as human neutrophil elastase (hne) and matrix metalloproteinases (mmp 2 and 9) inhibitors. - international journal of food properties. 2155-2164. |
s. m. mohd faudzi, s. w. leong, f. abas, m. f. f. mohd aluwi, k. rullah, k.w. lam, s. ahmad, c. l. tham, k. shaaria and n. h. lajis. (2015). synthesis, biological evaluation and qsar studies of diarylpentanoid analogues as potential nitric oxide inhibitors. - medchemcomm. 1069-1080. |
sze wei leong, siti munirah mohd faudzi, faridah abas, mohd fadhlizil fasihi mohd aluwi, kamal rullah, lam kok wai, mohd nazri abdul bahari, syahida ahmad, chau ling tham, khozirah shaari, nordin h. l. (2015). nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6- benzylidenecyclohexanone analogues, a novel series of curcuminoid and diarylpentanoid derivatives. - bioorganic & medicinal chemistry letters. 3330-3337. |
tham cl, hazeera harith h, wai lam k, joong chong y, singh cheema m, roslan sulaiman m, hj lajis n, ahmad israf d.. (2015). the synthetic curcuminoid bhmc restores endotoxin-stimulated huvec dysfunction:specific disruption on enzymatic activity of p38 mapk. - european journal of pharmacology. 1-11. |
kamal rullah, mohd fadhlizil fasihi, bohari m. yamin, mohd syukri baharuddin, nor hadiani ismail, hilwan yuda teruna, syed nasir abbas bukhari, ibrahim jantan, juriyati, khairana husain, lam kok wai. (2015). molecular characterization, biological activity, and in silico study of 2-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-6-methoxy-4h-chromen-4-one as a novel selective cox-2 inhibitor. - journal of molecular structure. 51-61. |
kamal rullah, mohd fadhlizil mohd aluwi, bohari yamin, mohd nazri abdul bahari, leong sze wei, syahida ahmad, faridah abas, nor hadiani ismail, ibrahim jantan, lam kok wai. (2014). inhibition of prostaglandin e2 production by synthetic minor prenylated chalcones and flavonoids: synthesis, biological activity, crystal structure and in silico evaluation. - bioorganic and medicinal chemistry letters. 24(16):3826-3834. |
radhakrishnan narayanaswamy, lam kok wai, faridah abas, and intan safinar ismail. (2014). molecular docking analysis of curcumin analogues as human neutrophil elastase inhibitors. - bangladesh journal of pharmacology. 9(1):77-82. |
maanvizhi s., narayanaswamy r., wai l.k., gnanamani a.. (2014). hpaa inhibitory effect of embelin and its metal complexes on diabetic complications: an approach with molecular docking studies. - journal of chemical and pharmaceutical research. 679 - 682. |
radhakrishnan narayanaswamy, majumder shymatak, suvro chatterjee, lam kok wai, gnanamani arumugam. (2014). inhibition of angiogenesis and nitric oxide synthase (nos), by embelin & vilangin using in vitro, in vivo & in silico studies. - advanced pharmaceutical bulletin. 543-548. |
sze wei leong, siti munirah mohd faudzi, faridah abas, mohd fadhlizil fasihi mohd aluwi, kamal rullah, lam kok wai, mohd nazri abdul bahari, syahida ahmad, chau ling tham, khozirah shaari and nordin h. (2014). synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents. - molecules. 16058-16081. |
chean hui ng, kamal rullah, mohd fadhlizil mohd aluwi, faridah abas, kok wai lam, intan safinar ismail, radakrishnan narayanaswamy, fadzureena jamaludin and khozirah shaari. (2014). synthesis and docking studies of 2,4,6-trihydroxy-3 geranylacetophenone analogs as potential lipoxygenase inhibitor. - molecules. 19:11645-11659. |
maanvizhi s., narayanaswamy r., wai l.k., gnanamani a.. (2014). molecular docking analysis of embelin and its metal complexes as human aldose reductase (har) inhibitor. - der pharmacia lettre. 165-168. |
syed nasir abbas bukhari, yasmin tajuddin, vanessa jacquelyne benedict, lam kok wai, ibrahim jantan, juriyati jalil, malina jasamai. (2014). synthesis and evaluation of chalcone derivatives as inhibitors of neutrophils` chemotaxis, phagocytosis and production of reactive oxygen species. - chemical biology and drug design. 83(2):198-206. |
syed nasir abbas bukhari, ibrahim jantan, lam kok wai, nordin haji lajis, faridah abbas, malina jasamai. (2013). synthesis and effects of pyrazolines and isoxazoles on the phagocytic chemotaxis and release of reactive oxygen species by zymosan stimulated human neutrophils. - medicinal chemistry. 9(8):1091-1098. |
koushik saha, kok wai lam, faridah abas, a. sazali hamzah, johnson stanslas, lim siang hui and nordin h. lajis. (2013). synthesis of damnacanthal, a naturally occurring 9,10-anthraquinone and its analogues, and its biological evaluation against five cancer cell lines. - medicinal chemistry research. 22(5): 2093-2104. |
radhakrishnan narayanaswamy, lam kok wai and intan safinar ismail. (2013). molecular docking analysis of natural compounds as human neutrophil elastase (hne) inhibitors. - journal of chemical and pharmaceutical research. 5(10):337-341. |
ibrahim jantan, syed nasir abbas bukhari, nordin haji lajis, faridah abas, lam kok wai, malina jasamai. (2012). effects of diarylpentanoid analogues of curcumin on chemiluminescence and chemotactic activities of phagocytes. - journal of pharmacy and pharmacology. 64(3):404-412. |
saleh m. salga, hapipah m. ali, mahmood a. abdullah, siddig i. abdelwahab, lam kok wai, michael j. c. buckle, sri devi sukumaran and a. hamid a. hadi. (2011). synthesis, characterization, acetylcholinesterase inhibition, molecular modeling and antioxidant activities of some novel schiff bases derived from 1-(2-ketoiminoethyl)piperazines. - molecules. 16(11):9316-9330. |
khozirah shaari, velan suppaiah, lam kok wai, johnson stanslas, bimo ario tejo, daud ahmad israf, faridah abas, intan safinar ismail, nor hasifi shuaib, seema zareen, nordin hj. lajis. (2011). bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase. - bioorganic & medicinal chemistry. 19(21):6340-6347. |