Penerbitan Terkini

mohd faizal ahmad, marjanu hikmah elias, norazilah mat jin, muhammad azrai abu, saiful effendi syafruddin, ani amelia zainuddin, nao suzuki, abdul kadir abdul karim.  (2023).  the spectrum of in vitro maturation in clinical practice: the current insight.  - frontiers in endocrinology.  1-13. 

lazim nurunnajah, elias marjanu hikmah, syafruddin saiful effendi, sutaji zulazmi, abu mohammad azrai, abdul karim abdul kadir, ugusman azizah, mokhtar mohd helmy, ahmad mohd faizal.  (2023).  expression of hoxa10 in endometriotic women following modulation of gonadotropin-releasing hormone receptor.  - medical journal of malaysia.  84. 

nurunnajah lazim, marjanu hikmah elias, zulazmi sutaji, abdul kadir abdul karim, mohammad azrai abu, azizah ugusman, saiful effendi syafruddin, mohd helmy mokhtar and mohd faizal ahmad.  (2023).  expression of hoxa10 gene in women with endometriosis: a systematic review.  - international journal of molecular sciences.  1-14. 

azizah ugusman, nur syakirah othman, adila a. hamid, shahidee zainal abidin, saiful effendi syafruddin, amilia aminuddin, norfilza mohd mokhtar, mohd faizal ahmad.  (2023).  microrna profiling of hyperglycemia-induced endothelial cells treated with metformin reveals novel micrornas.  - british journal of pharmacology.  81-82. 

saiful effendi bin syafruddin;muhiddin bin ishak;mohamad aimanuddin bin mohtar;low teck yew.  (2023).  functional validation of crispr-cas9 genetic screening hit hsf4 in supporting clear cell renal cell carcinoma pathogenesis.  -

ahmad rifqi bin md zain;tengku hasnan bin tengku abdul aziz;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar.  (2023).  optical sensor technique based on high quality factor suspended 1d photonic crystal (phc) structures for creatinine detection using non-invasive approach..  -

syazalina zahari , saiful effendi syafruddin , m. aiman mohtar.  (2023).  cancer cell secretome in driving breast cancer progression.  - scholarly community encyclopedia.  1-8. 

syazalina zahari, saiful effendi syafruddin and m. aiman mohtar.  (2023).  impact of the cancer cell secretome in driving breast cancer progression.  - cancers.  1-17. 

ryia illani my, nurul-syakima am, jia-shiun k, sazuita s, muhiddin i, saiful effendi s, francis yew ft, najwa farhah my, mohd ridhwan ar, norshahidah mn, nadiah a, isa md rose, ismail sagap, luqman mazlan, rahman jamal.  (2023).  whole genome sequencing of malaysian colorectal cancer patients reveals specific druggable somatic mutations.  - frontiers in molecular biosciences.  1-20. 

muhammad-redha abdullah-zawawi, mira-farzana mohamad-mokhtar, saiful effendi syafruddin, fateen farhana ibrahim, isa mohamed rose, roslan harun, nor azian abdul murad.  (2023).  mir-99a-5p and mir-148a-3p as candidate molecular biomarkers for the survival of lung cancer patients.  - malaysian applied biology.  87-100. 

asmaa y. abuhamad, nurul nadia mohamad zamberi, sakari vanharanta, siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin.  (2023).  cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma.  - international journal of molecular sciences.  1-14. 

kim jun cheng, elsa hanifah mejia mohamed, saiful effendi syafruddin, zaridatul aini ibrahim.  (2023).  interleukin-1 alpha and high mobility group box-1 secretion in olyinosinic: polycytidylic-induced colorectal cancer cells occur via ripk1-dependent mechanism and participate in tumourigenesis.  - journal of cell communication and signaling.  189-208. 

saiful effendi syafruddin, nurul nadia mohamad zamberi, asmaa y. abuhamad. sarah izzati izzat azrai, mohd khairul nizam mohd khalid , m. aiman mohtar.  (2023).  super enhancer-associated glucocorticoid receptor nr3c1 supports renal carcinoma growth by transcriptionally regulating the expression of pdk4, edn2 and il-6.  - 15th malaysia international genetics congress 2023.  1-19. 

m.aiman mohtar, syazalinazahari, nisasyakilaarahman , saifuleffendisyafruddin, muhammad-redhaabdullah-zawawi , lowteckyew, tedhupp.  (2023).  rna-seq analysis of crispr-cas9 targeted agr2 of breast cancer cells reveals potential modulators of its expression and secretion.  - 16th annual meeting of the korean society of medical oncology & 2023 international conference (ksmo 2023).  1. 

poh kuan wong, nurul nadia mohamad zamberi, saiful effendi syafruddin, fook choe cheah, norazrina azmi, jia xian law, eng wee chua.  (2023).  the promises and pitfalls of crispr-mediated base editing in stem cells.  - crispr journal.  196-215. 

syazalina zahari, saiful effendi syafruddin, low teck yew, tiannan guo, m. aiman mohtar.  (2023).  exploring the extracellular protein dynamics in crispr-targeted agr2 breast cancer cells: insights from high throughput dia-nn proteomics analysis.  - 16th annual meeting of the korean society of medical oncology & 2023 international conference (ksmo 2023).  1. 

yuh cai chia, sundharavalli ramayah , nurul nadia mohamad zamberi, mohamad aimanuddin mohtar , saiful effendi syafruddin.  (2023).  crispr/cas9: teknik penyuntingan dan modifikasi gen.  - 1. 

saiful effendi syafruddin.  (2022).  cellular and molecular biology of cancer: insights for early detection and therapeutics.  - 1-27. 

nurainie sayutti, muhammad azrai abu, saiful effendi, mohd faizal ahmad.  (2022).  elucidating the gene expression of grem 1 in cumulus cells and its association with oocytes quality in predicting pregnancy outcomes among pcos women.  - gynecological endocrinology the 20th world congress.  1. 

low teck yew;mohd firdaus bin mohd raih;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar;lee pey yee.  (2022).  elucidating the mechanism of secretion for human pro-metastatic agr2 protein.  -

alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low.  (2022).  short open reading frames (sorfs) and microproteins: an update on their identification and validation measures.  - journal of biomedical science.  1-15. 

saroor a. patel, shoko hirosue, paulo rodrigues, erika vojtasova, emma k. richardson, jianfeng ge, saiful e. syafruddin, alyson speed, evangelia k. papachristou, david baker, david clarke, ludovic wesolowski, , jason s. carroll, sakari vanharanta.  (2022).  the renal lineage factor pax8 controls oncogenic signalling in kidney cancer.  - nature.  999-1006. 

rashidah baharudin, muhiddin ishak, azliana muhamad yusof, sazuita saidin, saiful effendi syafruddin, wan fahmi wan mohamad nazarie, learn-han lee, nurul-syakima ab mutalib.  (2022).  epigenome-wide dna methylation profiling in colorectal cancer and normal adjacent colon using infinium human methylation 450k.  - diagnostics.  1-22. 

saiful effendi bin syafruddin, encik muhiddin bin ishak, mohamad aimanuddin bin mohtar.  (2022).  elucidating the mode of pdgfb-mediated activation of mtorc1 signalling pathway in clear cell renal cell carcinoma.  - 1-7. 

syazalina zahari , saiful effendi syafruddin, low teck yew , delphine fessart , ted hupp, m. aiman mohtar.  (2022).  elucidating the impact of crispr cas9 mediated agr2 knockout in the tumour microenvironment of breast cancer cells.  - the 46th annual conference of the malaysian society for biochemistry and molecular biology 2022 (msb.  1. 

asmaa y. abuhamad, nurul nadia mohamad zamberi, ling sheen, safaa m. naes, siti nur hasanah mohd yusuf, asilah ahmad tajudin, m. aiman mohtar, amir syahir amir hamzah, saiful effendi syafruddin.  (2022).  reverting tp53 mutation in breast cancer cells: prime editing workflow and technical considerations.  - cells.  1-16. 

nor azian abdul murad, nor azila muhammad azami, saiful effendi syafruddin, & razinah sharif.  (2022).  corona id 1.0 - pemerkasaan literasi kesihatan terhadap pelajar sekolah semasa era pandemik covid19.  - knovasi kongres dan pertandingan inovasi dalam pengajaran dan pembelajaran.  1. 

siti nur hasanah mohd yusuf, asmaa y. abuhamad, ling sheen, nurul nadia zamberi, mohamad aimanuddin mohtar, saiful effendi syafruddin.  (2022).  pdgfb paracrine signalling fuels growth promoting-mtorc1 hyperactivation in clear cell renal cell carcinoma (ccrcc).  - malaysian journal of medicine and health sciences.  46. 

nurul nadia mohamad zamberi, asmaa y. abuhamad, teck yew low, m. aiman mohtar, and saiful effendi syafruddin.  (2022).  the epigenetic modulators brd4 and p300 support klf6 super enhancer activity in promoting renal tumorigenesis.  - 46th annual conference of the malaysian society for biochemistry and molecular biology 2022 (msbmb46).  1-7. 

asmaa y. abuhamad, ling sheen, safaa m. naes, siti nur hasanah yusuf, nurul nadia zamberi, asilah ahmad tajudin, mohamad aimanuddin mohtar, amir syahir bin amir hamzah, saiful effendi syafruddin.  (2022).  crispr gene editing: the generation ooff genetically engineered breast cancer cells for interrogating the l194f p53 mutation.  - malaysian journal of medicine and health sciences.  46. 

nisa syakila a. rahman, syazalina zahari, saiful effendi syafruddin, mohd firdaus-raih, teck yew low, m. aiman mohtar.  (2022).  functions and mechanisms of protein disulfide isomerase family in cancer emergence.  - cell & bioscience.  1-19. 

saiful effendi syafruddin, mohamad aimanuddin mohtar.  (2022).  crispr-cas9 principles, applications and ethical issues.  - 1-61. 

saiful effendi syafruddin, mohamad aimanuddin mohtar.  (2022).  crispr-cas9 experimental workflow part i.  - 1-81. 

saiful effendi syafruddin, mohamad aimanuddin mohtar.  (2022).  crispr-cas9 experimental workflow part ii.  - 1-77. 

saiful effendi syafruddin, mohamad aimanuddin mohtar.  (2022).  bengkel crispr gene editing di institute of medical research (imr).  - 1-3. 

mohamad aimanuddin mohtar, saiful effendi syafruddin.  (2022).  protein agr2: bio penanda baru untuk pengesanan awal kanser.  - impak: kluster kesihatan & perubatan termaju.  28-29. 

asmaa y. i. abuhamad, mohamad aimanuddin mohtar, asilah ahmad tajudin, amir syahir amir hamzah, saiful effendi syafruddin.  (2021).  crispr-mediated generation of in vitro breast cancer models to study p53 gain of function mutation.  - asia pacific journal of molecular biology & biotechnology.  1. 

saiful effendi syafruddin.  (2021).  general crispr experimental workflow and case studies.  - emerging technologies in precision medicine.  1-38. 

siti nur hasanah mohd yusuf, asmaa y. abuhamad, ling sheen, nurul nadia zamberi, mohamad aimanuddin mohtar and saiful effendi syafruddin.  (2021).  pdgfb paracrine signalling fuels growth promoting mtorc1 hyperactivation in clear cell renal cell carcinoma (ccrcc).  - international conference on drug discovery and translational medicine 2021 (icddtm 21).  1-14. 

poh kuan wong, eng wee chua, norazrina azmi, saiful effendi syafruddin, martin kennedy.  (2021).  developing in vitro model using crispr gene-editing system to understand caffeine sensitivity in the developing brain.  - pharmacy research day 2021.  59. 

asmaa y. abuhamad, ling sheen, safaa m. naes, siti nur hasanah yusuf, nurul nadia zamberi, asilah ahmad tajudin, mohamad aimanuddin mohtar, amir syahir bin amir hamzah, saiful effendi syafruddin.  (2021).  crispr gene editing the generation of genetically engineered breast cancer cells for interrogating the l194f p53 mutation.  - international conference on drug discovery and translational medicine 2021 (icddtm 21).  1-14. 

malak hassn mesrati, saiful effendi syafruddin, m. aiman mohtar, amir syahir.  (2021).  cd44: a multifunctional mediator of cancer progression.  - biomolecules.  1-32. 

saiful effendi syafruddin , sheen ling, teck yew low and m aiman mohtar.  (2021).  more than meets the eye: revisiting the roles of heat shock factor 4 in health and diseases.  - biomolecules.  1-18. 

saiful effendi syafruddin.  (2021).  the interrogation of steroid addiction in renal cancer.  - 1-20. 

siti nur hasanah mohd yusuf, mira farzana mohamad mokhtar & saiful effendi syafruddin.  (2021).  the importance of bioinformatics in molecular biology research part i: introduction to bioinformatics & rna-seq.  - website umbi.  1. 

nur alyaa afifah md shahri, nur nadia razali & saiful effendi syafruddin.  (2021).  the importance of bioinformatics in molecular biology research part ii: network analysis & molecular docking, simulation.  - website umbi.  1. 

poh kuan wong, fook choe cheah, saiful effendi syafruddin, m aiman mohtar, norazrina azmi, pei yuen ng, eng wee chua.  (2021).  crispr gene-editing models geared toward therapy for hereditary and developmental neurological disorders.  - frontiers in pediatrics.  1-15. 

nisa syakila a rahman, teck yew low, saiful effendi syafruddin, m. aiman mohtar.  (2021).  functional interrogation of crispr-cas9 mediated agr2 knockout in metastatic triple negative breast cancer cells.  - asm science journal.  91. 

asmaa y. i. abuhamad, mohamad aimanuddin mohtar, asilah ahmad tajudin, amir syahir bin amir hamzah, saiful effendi syafruddin.  (2021).  crispr-mediated generation of in vitro breast cancer models to study p53 ain-of-function mutation.  - 4th international conference on molecular biology & biotechnology.  1-19. 

teck yew low, saiful effendi syafruddin, m. aiman mohtar, adaikkalam vellaichamy, nisa syakila a rahman, yuh-fen pung & chris soon heng tan.  (2021).  recent progress in mass spectrometry-based strategies for elucidating protein-protein interactions.  - cellular and molecular life sciences.  5325-5339. 

saiful effendi syafruddin.  (2021).  genome editing : are we ready for that?.  - 1-32. 

siti nur hasanah mohd. yusof, saiful effendi syafruddin.  (2021).  pdgfb paracrine signalling fuels mtorc1 hyperactivation in ccrcc.  - 1-20. 

nisa syakila a rahman, saiful effendi syafruddin, teck yew low, m. aiman mohtar.  (2021).  functional interrogation of crispr-cas9 mediated agr2 knockout in metastatic triple negative breast cancer cells.  - ysn-asm international scientific virtual conference (isvc) 2021.  1. 

saiful effendi syafruddin, wan fahmi wan mohamad nazarie, nurshahirah ashikin moidu, bee hong soon, m. aiman mohtar.  (2021).  integration of rna-seq and proteomics data identifies glioblastoma multiforme surfaceome signature.  - bmc cancer.  1-13. 

nazihah abd jalal, norliza ismail & dr. saiful effendi syafruddin.  (2021).  hati berlemak: kesan kepada kesihatan.  - website umbi.  1. 

saiful effendi bin syafruddin.  (2020).  elucidating the mode of pdgfb-mediated activation of mtorc1 signaling pathway in clear cell renal cell carcinoma.  - makna cancer research award 2019 ceremony (mrca 2019).  1-14. 

m. aiman mohtar, saiful effendi syafruddin, siti nurmi nasir, low teck yew.  (2020).  revisiting the roles of pro-metastatic epcam in cancer.  - biomolecules.  1-19. 

saiful effendi syafruddin.  (2020).  investigating the glucocorticoid receptor nr3c1 role in supporting clear cell renal cell carcinoma pathogenesis.  - 1. 

saiful effendi syafruddin.  (2020).  investigating the glucocorticoid receptor nr3c1 role in supporting clear cell renal cell carcinoma pathogenesis.  - celebrating the legacy of dr ranjeet bhagwan singh: paradigm shift in medical research.  1-7. 

saiful e. syafruddin, m. aiman mohtar, wan fahmi wan mohamad nazarie, teck yew low.  (2020).  two sides of the same coin: the roles of klf6 in physiology and pathophysiology.  - biomolecules.  1-22. 

saiful effendi syafruddin.  (2020).  elucidating the mode of pdgfb-mediated activation of mtorc1 signaling pathway in clear cell renal cell carcinoma.  - makna cancer research award 2019 ceremony (mrca 2019).  1. 

nurshahirah ashikin moidu, nisa syakila a rahman, saiful effendi syafruddin, teck yew low, m. aiman mohtar.  (2020).  secretion of pro-oncogenic agr2 protein in cancer.  - heliyon.  1-11. 

nur fadhlina mohamad pakarulrazy, saiful effendi syafruddin, nurul syakima ab mutalib, azlina ahmad annuar, shen yang lim, rahman jamal, nor azian abdul murad, norlinah mohamed ibrahim.  (2020).  glucocerebrosidase genetic variants in malays with early and late-onset parkinson's disease.  - neurology asia.  39-46. 

safaa m. naes, sharaniza ab. rahim, musalmah binti mazlan, saiful effendi syafruddin, m. aiman mohtar, amirah abdul rahman.  (2020).  ent2 gene expression in the different stages of colorectal cancer.  - international e-conference on biotechnology, bioinformatics, and biomedicine.  1. 

mohamad aimanuddin mohtar, saiful effendi syafruddin, amir syahir bin amir hamzah.  (2020).  teknologi penyuntingan gen crispr dan teknik terbaharu pengesanan covid-19.  - majalahsains.com.  1-2. 

mohamad aimanuddin mohtar, saiful effendi syafruddin,.  (2020).  crispr protocol for crispr-mediated gene editing in human cell lines workshop 2019.  - 1-24. 

saiful e. syafruddin, paulo rodrigues, erika vojtasova, saroor a. patel, m. nazhif zaini, johanna burge, anne y. warren, grant d. stewart, tim eisen, dora bihary, shamith a. samarajiwa, sakari vanharanta.  (2019).  a klf6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma.  - nature communication.  1-13. 

saiful effendi syafruddin, mohamad aimanuddin mohtar, tan shing cheng, nadiah abu, nor aidatulakma abdullah@muda, nurul syakima ab mutalib, chin siok fong, neoh hui min, rahman jamal, nor azian abdul murad.  (2019).  malaysian higher institution centres of excellence (hicoe) official compendium.  - 244. 

saiful effendi bin syafruddin, paulo rodrigues, erika vojtasova, saroor patel, dora bihary, shamith samarajiwa, sakari vanharanta.  (2018).  a klf6-dependent pdgfb-mtor signaling loop links lipid homeostasis and tumor growth in renal cancer.  - abcam cancer and metabolism 2018.  43. 

m. nazhif zaini, saroor a. patel, saiful e. syafruddin, paulo rodrigues & sakari vanharanta.  (2018).  endogenous hif2a reporter systems for high-throughput functional screening.  - scientific reports. 

siti syazani suhaimi, nurul-syakima ab mutalib, sheau s. khor, reena rahayu md zain, saiful effendi syafruddin, nadiah abu, ahmad zailani hatta mohd dali and rahman jamal.  (2018).  targeted next-generation sequencing identifies actionable targets in estrogen receptor positive and estrogen receptor negative endometriod endometrial cancer.  - frontiers in pharmacology. 

paulo rodrigues, saroor a. patel, louise harewood, ioana olan, erika vojtasova, saiful e. syafruddin, m. nazhif zaini, emma k. richardson, johanna burge, anne y. warren, grant d. stewart, kourosh saeb-parsy, shamith a samarajiwa, and sakari vanharanta.  (2018).  nf-jb-dependent lymphoid enhancer co-option promotes renal carcinoma metastasis.  - cancer discovery. 

siti syazani suhaimi, nurul syakima ab mutalib, khor sheau sean, saiful effendi syafruddin, nadiah abu, reena rahayu md zain, ahmad zailani hatta mohd dali, rahman jamal.  (2017).  elucidation of signal transduction pathways involved in molecular subtypes of endometrial cancer.  - 7th regional conference on molecular medicine (rcmm) in conjunction with 3rd national conference for cancer research 2017. 

noraidatulakma abdullah, nor azian abdul murad, ezanee azlina mohd haniff, saiful effendi syafruddin, john attia, christopher oldmeadow, mohd arman kamaruddin, nazihah abd jalal, norliza ismail, muhiddin ishak, rodney j. scott & elizabeth holliday.  (2017).  genetic and non-genetic studies of type 2 diabetes in the multi-ethnic malaysian cohort.  - 7th regional conference on molecular medicine in conjuction with 3rd national conference for cancer research. 10th-12th november 2017, kuala lumpur, malaysia.. 

noraidatulakma abdullah, nor azian abdul murad, ezanee azlina mohd haniff, saiful effendi syafruddin, john attia, christopher oldmeadow, mohd arman kamaruddin, nazihah abd jalal, norliza ismail, muhiddin ishak, rahman jamal, rodney j. scott, elizabeth gh.  (2017).  predicting type 2 diabetes using genetic and environmental risk factors in a multi-ethnic malaysian cohort.  - public health.  31-38. 

shafina nadiawati abdul, nurul syakima ab mutalib, khor s. sean, saiful e. syafruddin, muhiddin ishak, ismail sagap, luqman mazlan, isa m. rose, nadiah abu, norfilza m. mokhtar and rahman jamal.  (2017).  molecular characterization of somatic alterations in dukes b and c colorectal cancers by targeted sequencing.  - frontiers in pharmacology.  1-19. 

nor azian abd murad,saiful effendi,muhiddin ishak,mohd ridhwan,sri noraima,soo bee hong,azizi abu bakar,farizal fadzil,jegan thanabalan,toh charng jeng,isa mohamed rose,roslan harun, rahman jamal.  (2016).  identification of missense mutations in genes related to cancer pathways in glioma using the personal genome machine.  - asia pacific jurnal of molecular medicine (apjmm).  1-10. 

n abdullah, na abdul murad, j attia, c oldmeadow, ea mohd haniff, se syafruddin, n abd jalal, n ismail, m ishak, r jamal, rj scott and eg holliday.  (2015).  characterizing the genetic risk for type 2 diabetes in a malaysian multi-ethnic cohort.  - diabetic medicine.  1377-1384. 

nf mohamad pakarul razy, na abdul murad, se syafruddin, a ahmad-annuar, sy lim, nm ibrahim, r jamal.  (2015).  glucocerebrosidase mutations in malay parkinson`s disease patients.  - public health genomics.  23. 

fateen farhana ibrahim, rahman jamal, saiful effendi syafruddin, nurul syakima ab mutalib, sazuita saidin, reena rahayu mdzin, mohammad manir hossain mollah, norfilza mohd mokhtar.  (2015).  microrna-200c and microrna-31 regulate proliferation, colony formation, migration and invasion in serous ovarian cancer..  - journal of ovarian research.  1-14. 

nurul-syakima ab mutalib, saiful effendi syafruddin, reena rahayu md zain, ahmad zailani hatta mohd dali, ryia illani mohd yunos, sazuita saidin, rahman jamal and norfilza m mokhtar.  (2014).  molecular characterization of serous ovarian carcinoma using a multigene next generation sequencing cancer panel approach.  - bmc research notes.  1-10. 

fateen farhana ibrahim, saiful effendi syafruddin, siti aishah mdali, reena mdzin, rahman jamal, norfilza mohd mokhtar.  (2013).  determining micrornas profile in formalin-fxed paraffin-embedded samples of metastatic serous ovarian cancer.  - 1st national conference for cancer research & 5th regional conference on molecular medicine.