prof. dr. sheila nathan

pensyarah universiti

jabatan sains biologi & bioteknologi

No. sambungan :  60389213862

No. rasmi:
UKM : 03 8921 5555



   Biografi/ Biography :

  • My research focuses on the pathogenesis of the tropical pathogen Burkholderia pseudomallei and the host defense mechanism against the infection. Major research collaborations with Stanford University (USA) University of Sheffield (UK) and KAUST (Republic of Saudi Arabia) have contributed to significant new knowledge on the bacterium’s virulence and pathogenic mechanisms, as well as the failure of the host immune response. The research findings have led to >100 research papers, review articles, and book chapters, as well as invitations to speak at national and international conferences and review grant applications for funders from Malaysia, UK, Switzerland, Austria and Italy. I have successfully trained >50 graduate students. I am also an Associate Editor (Prokaryote Genomics) for BMC Genomics and a regular peer reviewer for international journals in the field.

  • george w. mobbs, adli a. aziz, samuel r. dix, g. m. blackburn, sveta e. sedelnikova, thomas c. minshull, mark j. dickman, patrick j. baker, sheila nathan, mohd firdaus raih, david w. rice.  (2022).  molecular basis of specificity and deamidation of eif4a by burkholderia lethal factor 1.  - communications biology.  1-11. 

     

    f.-k. loh, s. nathan, s.-c. chow, c.-m. fang.  (2022).  cytolysin a-mediated protein exportation efficiency and its role in enhancing the fitness of live recombinant salmonella typhi vaccine strain.  - letters in applied microbiology.  820-830. 

     

    le jie lee, norfarazieda hassan, siti zuleha idris, suresh kumar subbiah, heng fong seow, norhafizah mohtaruddin, kian meng chang, raudhawati osman, hishamshah mohd ibrahim, sheila nathan, maha abdullah.  (2022).  differential regulation of nk cell receptors in acute lymphoblastic leukemia.  - journal of immunology research.  1-13. 

     

    mohd amin azuwar, nor azlan nor muhammad, nor afiqah-aleng, nurul-syakima ab mutalib, najwa farhah md. yusof, ryia illani mohd yunos, muhiddin ishak, sazuita saidin, isa mohamed rose, ismail sagap, luqman mazlan, zairul azwan mohd azman, musalmah mazlan.  (2022).  tcga-my: a systematic repository for systems biology of malaysian colorectal cancer.  - life.  1-14. 

     

    ethel jeyaseela jeyaraj; sheila nathan; yau yan lim; wee sim choo.  (2022).  antibiofilm properties of clitoria ternatea flower anthocyanin-rich fraction towards pseudomonas aeruginosa.  - access microbiology.  1-12. 

     

    george w. mobbs, adli a. aziz, samuel r. dix, g. m. blackburn, sveta e. sedelnikova, thomas c. minshull, mark j. dickman, patrick j. baker, sheila nathan, mohd firdaus raih, david w. rice.  (2022).  molecular basis of specificity and deamidation of eif4a by burkholderia lethal factor 1.  - communications biology.  1-11. 

     

    le jie lee, norfarazieda hassan, siti zuleha idris, suresh kumar subbiah, heng fong seow, norhafizah mohtaruddin, kian meng chang, raudhawati osman, hishamshah mohd ibrahim, sheila nathan, maha abdullah.  (2022).  differential regulation of nk cell receptors in acute lymphoblastic leukemia.  - journal of immunology research.  1-13. 

     

    mohd amin azuwar, nor azlan nor muhammad, nor afiqah-aleng, nurul-syakima ab mutalib, najwa farhah md. yusof, ryia illani mohd yunos, muhiddin ishak, sazuita saidin, isa mohamed rose, ismail sagap, luqman mazlan, zairul azwan mohd azman, musalmah mazlan.  (2022).  tcga-my: a systematic repository for systems biology of malaysian colorectal cancer.  - life.  1-14. 

     

    r. arushothy, s. nathan, n. ahmad, f. amran, r. hashim, m.r. mohd ali, h.f. zamri, n. samsuddin.  (2021).  genome-wide relatedness of burkholderia pseudomallei isolates in malaysia.  - international journal of infectious diseases.  370. 

     

    nurnabila syafiqah muhamad rizal, hui-min neoh, ramliza ramli, petrick @ ramesh a/l k periyasamy, alfizah hanafiah ,muttaqillah najihan abdul samat, toh leong tan, kon ken wong, sheila nathan, sylvia chieng, seow hoon saw, bee yin khor.  (2021).  16s rrna gene next-generation sequencing (16sngs) for bacterial pathogen identification: pilot study in a malaysian teaching hospital.  - international journal of infectious diseases.  180-203. 

     

    f.-k. loh, s. nathan, s.-c. chow, c.-m. fang.  (2022).  cytolysin a-mediated protein exportation efficiency and its role in enhancing the fitness of live recombinant salmonella typhi vaccine strain.  - letters in applied microbiology.  820-830. 

     

    rui-rui wong, khairom-muslihin baharom, ahmad-kamal ghazali, abdul karim russ hassan, sheila nathan.  (2021).  phenotype and virulence assessment of a burkholderia pseudomallei soil isolate from malaysia.  - sains malaysiana.  1233-1241. 

     

    siew-wei seah, nur siti fatimah mohamad jamil, yann-yin lee, cin kong, sheila nathan, kiew-lian wan.  (2020).  prodigiosin serratia marcescens tidak bersifat tosik terhadap ceanorhabditis elegans.  - sains malaysiana.  775-784. 

     

    sue-kim ho, mandeepal singh atar singh, sheila nathan, kiew-lian wan.  (2020).  pengimunan protein rekombinan sag2 eimeria tenella melindungi ayam terhadap kesan penyakit koksidiosis.  - sains malaysiana.  971-978. 

     

    sheila nathan.  (2020).  transcriptome profiling to understand host-bacteria interactions: past, present and future.  - science asia.  503-513. 

     

    f.-k. loh, s. nathan, s.-c. chow, c.-m. fang.  (2022).  cytolysin a-mediated protein exportation efficiency and its role in enhancing the fitness of live recombinant salmonella typhi vaccine strain.  - letters in applied microbiology.  820-830. 

     

    george w. mobbs, adli a. aziz, samuel r. dix, g. m. blackburn, sveta e. sedelnikova, thomas c. minshull, mark j. dickman, patrick j. baker, sheila nathan, mohd firdaus raih, david w. rice.  (2022).  molecular basis of specificity and deamidation of eif4a by burkholderia lethal factor 1.  - communications biology.  1-11. 

     

    mohd amin azuwar, nor azlan nor muhammad, nor afiqah-aleng, nurul-syakima ab mutalib, najwa farhah md. yusof, ryia illani mohd yunos, muhiddin ishak, sazuita saidin, isa mohamed rose, ismail sagap, luqman mazlan, zairul azwan mohd azman, musalmah mazlan.  (2022).  tcga-my: a systematic repository for systems biology of malaysian colorectal cancer.  - life.  1-14. 

     

    le jie lee, norfarazieda hassan, siti zuleha idris, suresh kumar subbiah, heng fong seow, norhafizah mohtaruddin, kian meng chang, raudhawati osman, hishamshah mohd ibrahim, sheila nathan, maha abdullah.  (2022).  differential regulation of nk cell receptors in acute lymphoblastic leukemia.  - journal of immunology research.  1-13. 

     

    r. arushothy, s. nathan, n. ahmad, f. amran, r. hashim, m.r. mohd ali, h.f. zamri, n. samsuddin.  (2021).  genome-wide relatedness of burkholderia pseudomallei isolates in malaysia.  - international journal of infectious diseases.  370. 

     

    chee-hoo yip, orr yarkoni, james ajioka, kiew-lian wan & sheila nathan.  (2018).  development of a codon optimization strategy using the efor red reporter gene as a test case.  - the 2017 ukm fst postgraduate colloquium, aip conference proceedings. 

     

    sue-kim ho, sheila nathan & kiew-lian wan.  (2016).  expression and immunological characterisation of eimeria tenella glycosylphosphatidylinositol-anchored surface antigen-5.  - the 2016 ukm fst postgraduate colloquium, aip conference proceedings.  1-5. 

     

    siew-wei seah, sheila nathan & kiew-lian wan.  (2016).  toxicity evaluation of prodigiosin from serratia marcescens in a caenorhabditis elegans model.  - the 2016 ukm fst postgraduate colloquium, aip conference proceeding.  1-4. 

     

    dr.nurina anuar, dr.nazlina ibrahim, prof.sheila nathan, dr.jamaliah md jahim, prof. madya dr.siti rozaimah sheikh abdullah.  (2008).  pembangunan bank sel terciri dan sistem pengkulturan untuk penghasilan protein recombinan oleh sel mamalia.  - seminar pemantauan projek penyelidikan (gup) 2007. 

     

    sylvia chieng, sheila nathan.  (2021).  burkholderia pseudomallei: jangkitan dan pengesanan.  - 146. 

     

    nuruljannah mohd yusof, wong yee chin, sheila nathan.  (2018).  siri penyelidikan biosains dan bioteknologi 2018.  - 4. 

     

    teh chin loong, yee chin wong, ahmad kamal ghazali, sheila nathan.  (2018).  siri penyelidikan biosains dan bioteknologi 2018.  - 5. 

     

    chen zhe kin, wong yee chin, ahmad kamal ghazali, sheila nathan.  (2018).  siri penyelidikan biosains dan bioteknologi 2018.  - 5. 

     

    goh ying xian, wong yee chin, ahmad kamal ghazali, sheila nathan.  (2018).  siri penyelidikan biosains dan bioteknologi 2018.  - 4. 

     

    sheila nathan, sylvia chieng, paul vijay kingsley, anand mohan, yuwana podin, mong-how ooi, vanitha mariappan, kumutha malar vellasamy, jamuna vadivelu, sylvia daim, soon-hin how.  (2019).  global burden and challenges of melioidosis.  - 19. 

     

    goh ying xian, wong yee chin, ahmad kamal ghazali, sheila nathan.  (2018).  siri penyelidikan biosains dan bioteknologi 2018.  - 4. 

     

    nur afiqah mohd yatim, wong yee chin, wong rui rui, ahmad kamal ghazali, sheila nathan, doris quay huai xia.  (2018).  siri penyelidikan biosains dan bioteknologi 2018.  - 5. 

     

    nuruljannah mohd yusof, wong yee chin, sheila nathan.  (2018).  siri penyelidikan biosains dan bioteknologi 2018.  - 4. 

     

    teh chin loong, yee chin wong, ahmad kamal ghazali, sheila nathan.  (2018).  siri penyelidikan biosains dan bioteknologi 2018.  - 5. 

     

    sylvia chieng, sheila nathan.  (2021).  burkholderia pseudomallei: jangkitan dan pengesanan.  - 146. 

     

    ahmad bazli bin ramzi;sheila nathan;neoh hui min;nurul hanun binti ahmad raston.  (2021).  engineering bacterial biosensor for detecting staphylococcal infection by reconstructing staphylococcus aureus quorum sensing system.  -

     

    sylvia chieng;sheila nathan.  (2021).  characterization of novel virulence factors involved in burkholderia pseudomallei intracellular survival.  -

     

    neoh hui min;sheila nathan;a. rahman bin a. jamal;alfizah binti hanafiah;wong kon ken;petrick @ ramesh a/l k periyasamy;ramliza binti ramli;muttaqillah najihan bin abdul samat;tan toh leong;ang mia yang;sylvia chieng.  (2021).  transforming pathogen identification in an era of the 4th industrial revolution: development of a decision-making algorithm for rapid pathogen identification in the clinical microbiology laboratory .  -

     

    fadhar, n. f., shuhaimi, n., raih, m. f., nathan, s., ng, c. l..  (2020).  overexpression and purification of bpsl0738, a hypothetical protein potentially involves in host-pathogen interaction in burkholderia pseudomallei.  - asian regional conference on systems biology 2020 (arcsb2020).  111. 

     

    sheila nathan, doris quay huai xia, mohd fareed mohd sairi, noor liyana sukiran, nurulhikma md isa, shazilah kamaruddin.  (2020).  buletin citra-bsbt bil.6.  - 1-20.