Biografi/ Biography :
Suzana binti Makpol is a Professor of Biochemistry at Faculty of Medicine, Universiti Kebangsaan Malaysia. She graduated from Universiti Kebangsaan Malaysia with Bachelor of Science Hons (Clinical Biochemistry) in 1992 and obtained her PhD (Medical Biochemistry) from the same university in 1997. She then went to Graduate School of Pharmaceutical Sciences, Hokkaido University, Japan in year 2000 for research training and did an attachment at Linus Pauling Institute, Oregon State University, USA in 2008. Professor Makpol has been investigating the molecular changes that occur with ageing and elucidating the molecular mechanisms of natural compounds such as palm tocotrienols, microalgae Chlorella vulgaris, gelam honey, Piper betle and Zingiber officinale Roscoe (ginger) in delaying ageing with emphasis on intracellular signaling pathways and its regulation by genes, transcription factors and micro RNAs. In her studies, she has been using stress-induced premature senescence (SIPS) model of human diploid fibroblasts, replicative senescence model of human diploid fibroblasts, and myoblasts which represent cellular ageing besides the animal model. She has also developed the in vitro model of Alzheimer’s disease carrying the double Swedish/Indiana mutations. She has published more than 100 papers in peer-reviewed international journals and presented more than 150 seminar papers in local and international conferences. She has held many research grants and is currently involved in several research projects.
yan qi tan, c-khai loh, shamin mohd saffian, suzana makpol. (2024). improved hplc method with automated pre-column sample derivatisation for serum pegylated l-asparaginase activity measurement in paediatric acute lymphoblastic leukaemia patients. - journal of pharmaceutical and biomedical analysis. 1-9.
sophia ogechi ekeuku, ahmad baihaqi ahmad shahzalli, jen kit tan, suzana makpol. (2024). untargeted metabolomic profiling on the effect of ginger on rat hepatic changes during ageing. - journal of functional foods. 1-14.
tan jen kit;suzana binti makpol;norfilza mohd mokhtar;goon jo aan;khairul najmi bin muhammad nawawi. (2024). exploring the roles of mirnas on lipidome of metabolic-associated fatty liver disease (mafld) cell models. - . .
kirushmita anbualakan, nur qisti tajul urus, suzana makpol, adawiyah jamil, elvy suhana mohd ramli, suria hayati md pauzi and norliza muhammad. (2023). a scoping review on the effects of carotenoids and flavonoids on skin damage due to ultraviolet radiation. - nutrients. 1-17.
zaizuhana shahrim, suzana makpol, geok chin tan, kamariah ibrahim, zafarizal aldrin azizul hasan. (2023). inhibition of mir-223-3p by topically applied palm tocotrienol rich fractions (trf) improves angiogenesis in lep ob/ob cutaneous wound healing model. - international meeting 47th annual conference of the malaysian society for biochemistry and molecular biology. 108.
sophia ogechi ekeuku, ahmad baihaqi ahmad shahzalli, jen kit tan, suzana makpol. (2024). untargeted metabolomic profiling on the effect of ginger on rat hepatic changes during ageing. - journal of functional foods. 1-14.
yan qi tan, c-khai loh, shamin mohd saffian, suzana makpol. (2024). improved hplc method with automated pre-column sample derivatisation for serum pegylated l-asparaginase activity measurement in paediatric acute lymphoblastic leukaemia patients. - journal of pharmaceutical and biomedical analysis. 1-9.
kartthigeen tamel selvan, jo aan goon, suzana makpol, jen kit tan. (2023). effects of microalgae on metabolic syndrome. - antioxidants. 1-23.
jk tan, sna zakaria,g gunasekaran, nf abdul sani, ml nasaruddin, f jaafar, zh abu bakar, aiz amir hamzah, kn nor aripin, md mohd rani, na noh, ha damanhuri, m mazlan, s makpol, wz wan ngah. (2023). metabolomics profiling of age-associated metabolites in malay population. - oxidative medicine and cellular longevity. 1-12.
azraul mumtazah razak, siti nor asyikin zakaria, nur fathiah abdul sani, nazirah ab rani, nur haleeda hakimi, mazlina mohd said, jen kit tan, han kwang gan, mariam firdhaus mad nordin and suzana makpol. (2023). a subcritical water extract of soil grown zingiber officinale roscoe: comparative analysis of antioxidant and anti-inflammatory effects and evaluation of bioactive metabolites. - frontiers in pharmacology. 1-17.
jen kit tan, sakinah husna abdul razak, nazirah ab rani, nur haleeda hakimi, hanafi ahmad damanhuri, suzana makpol & wan zurinah wan ngah. (2022). effects of age and tocotrienol-rich fraction on mitochondrial respiratory complexes in the hippocampus of rats. - sains malaysiana. 249-259.
yasmin anum mohd yusof, shailah abdullah, nur fatin nabilah mohd sahardi, wan zurinah wan ngah & suzana makpol. (2022). zingiber officinale and piper betle extracts enhanced the chemopreventive effect against colon cancer cells by targeting caspase-mediated apoptosis. - sains malaysiana. 217-237.
zaizuhana shahrim; suzana makpol; geok chin tan; nurul aishah muhammad and zafarizal aldrin azizul hasan. (2022). topical application of the palm tocotrienol-rich fraction (trf) enhances cutaneous wound healing in type 2 diabetic mice. - journal of oil palm research. 546-561.
khaizurin tajul arifin, noor ikhwan shansuddin, norwahidah abdul karim & suzana makpol. (2022). hot water extract from saccharomyces cerevisiae scavenges dpph and reduces senescence associated b-galactosidase (sa-b-gal) in human dermal fibroblasts. - sains malaysiana. 2415-2424.
sheng zhang lim, raja affendi raja adli, suzana makpol & eng wee chua. (2022). therapeutic monitoring of thiopurine metabolites: validation of an hplc method and preliminary findings from a small cohort of malaysian patients with inflammatory bowel disease. - sains malaysiana. 1847-1859.
yan qi tan, c-khai loh, shamin mohd saffian, suzana makpol. (2024). improved hplc method with automated pre-column sample derivatisation for serum pegylated l-asparaginase activity measurement in paediatric acute lymphoblastic leukaemia patients. - journal of pharmaceutical and biomedical analysis. 1-9.
sophia ogechi ekeuku, ahmad baihaqi ahmad shahzalli, jen kit tan, suzana makpol. (2024). untargeted metabolomic profiling on the effect of ginger on rat hepatic changes during ageing. - journal of functional foods. 1-14.
kah hui yap, shahrul azmin, suzana makpol, hanafi ahmad damanhuri, muzaimi mustapha, jemaima che hamzah, norlinah mohamed ibrahim. (2023). profiling neuroprotective potential of trehalose in animal models of neurodegenerative diseases: a systematic review. - neural regeneration research. 1179-1185.
ang hui phing, suzana makpol, muhammad luqman nasaruddin, wan asyraf wan zaidi, nurul saadah ahmad and hashim embong. (2023). altered tryptophan-kynurenine pathway in delirium: a review of the current literature. - international journal of molecular sciences. 1-28.
kartthigeen tamel selvan, jo aan goon, suzana makpol, jen kit tan. (2023). effects of microalgae on metabolic syndrome. - antioxidants. 1-23.
amnani aminuddin, eng wee chua, chee-onn leong, suzana makpol, pei yuen ng. (2021). potential use of a heat shock protein 90 inhibitor, geldanamycin, in combination therapy with cisplatin in oral squamous cell carcinoma. - mspp 34th scientific meeting 2021. 61-62.
yasmin anum mohd yusof, junaidah@maimunah hassan basri, nor ashiken mokti, suhana mohd saad, suhaniza sulaiman, nur sajaratul binti yahya, emey suhana mohd azamai, suzana makpol, wan zurinah wan ngah. (2011). chlorella vulgaris : a miracle plant?. - 4th international conference on modeling, simulation and applied optimization, icmsao 2011. .
suzana makpol, nur fathiah abdul sani. (2022). panduan pengukuran status oksidatif. - . 9.
tan jen kit, suzana makpol. (2022). panduan pengukuran status oksidatif. - . 11.
suzana makpol, nur fathiah abdul sani. (2022). panduan pengukuran status oksidatif. - . 13.
goon jo aan, suzana makpol, zakiah jubri. (2022). panduan pengukuran status oksidatif. - . 1.
tan jen kit;suzana binti makpol;norfilza mohd mokhtar;goon jo aan;khairul najmi bin muhammad nawawi. (2024). exploring the roles of mirnas on lipidome of metabolic-associated fatty liver disease (mafld) cell models. - . .
zaizuhana shahrim, suzana makpol, geok chin tan, kamariah ibrahim, zafarizal aldrin azizul hasan. (2023). inhibition of mir-223-3p by topically applied palm tocotrienol rich fractions (trf) improves angiogenesis in lep ob/ob cutaneous wound healing model. - international meeting 47th annual conference of the malaysian society for biochemistry and molecular biology. 108.
nur fatin nabilah mohd sahardi, nur fathiah abdul sani, siti nor asyikin zakaria, nur baitee a. rahim, fazaine zakaria, amilia aminuddin, jen kit tan, mariam firdhaus mad nordin, suzana makpol. (2023). effects of ginger (zingiber officinale roscoe) on oxidative stress and proteome changes among the elderly. - international meeting 47th annual conference of the malaysian society for biochemistry and molecular biology. 90.
norwahidah binti abdul karim;suzana binti makpol;yasmin anum binti mohd yusof. (2023). determination of mitochondrial function underlying idiopathic autism spectrum disorders and its modulation by kelulut honey. - . .
kartthigeen tamel selvan, jo aan goon, suzana makpol, jen kit tan. (2023). effects of microalgae on metabolic syndrome. - encyclopedia. 1.
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| TOCOTRIENOL AS A SENOLYTIC AGENT: A PHASE 2 CLINICAL TRIAL | malaysian palm oil board | 47.5% (2022-11-29 sehingga 2027-01-30) |
| TOCOTRIENOL AS A SENOLYTIC AGENT: A PHASE 2 CLINICAL TRIAL | davos life science sdn bhd | 47.5% (2022-11-29 sehingga 2027-01-30) |
| RELATIONSHIP BETWEEN GUT AND NASAL MICROBIOME PROFILES WITH T-HELPER PATHWAYS IN PERSISTENT MODERATE-SEVERE ALLERGIC RHINITIS CHILDREN WITH VITAMIN D SUPPLEMENTATION | pharma nord sdn bhd | 66.6% (2023-07-24 sehingga 2025-07-23) |
| EXPLORING NEURONAL EXPANSION BY PHOENIXIN IN PARKINSON`S DISEASE IN VITRO MODEL | monash university | 57.1% (2023-10-01 sehingga 2025-09-30) |
| UNRAVELLING THE ECOBIOSOCIAL FACTORS IN COLORECTAL CANCER INITIATION AND PROGRESSION | cancer survivors malaysia | 91.8% (2021-09-07 sehingga 2025-03-06) |
| ELUCIDATING THE METABOLIC PATHWAYS OF DEVELOPMENT OF SMALL FIBER NEUROPATHY AND MODULATION BY PALM TOCOTRIENOL RICH FRACTION | sime darby oils nutrition sdn bhd | 91.8%(2021-09-07 sehingga 2025-03-06) |
| CHARACTERISATION OF GUT MICROBIOME IN AGEING AND ITS MODULATION BY GINGER EXTRACTS IN RATS ANIMAL MODEL | am zaideen ventures sdn bhd | 91.8%(2022-10-01 sehingga 2025-03-31) |