prof. dr. suzana binti makpol

pensyarah universiti

jabatan biokimia

No. rasmi:
UKM : 03 8921 5555



   Biografi/ Biography :

  • Suzana binti Makpol is a Professor of Biochemistry at Faculty of Medicine, Universiti Kebangsaan Malaysia. She graduated from Universiti Kebangsaan Malaysia with Bachelor of Science Hons (Clinical Biochemistry) in 1992 and obtained her PhD (Medical Biochemistry) from the same university in 1997. She then went to Graduate School of Pharmaceutical Sciences, Hokkaido University, Japan in year 2000 for research training and did an attachment at Linus Pauling Institute, Oregon State University, USA in 2008. Professor Makpol has been investigating the molecular changes that occur with ageing and elucidating the molecular mechanisms of natural compounds such as palm tocotrienols, microalgae Chlorella vulgaris, gelam honey, Piper betle and Zingiber officinale Roscoe (ginger) in delaying ageing with emphasis on intracellular signaling pathways and its regulation by genes, transcription factors and micro RNAs. In her studies, she has been using stress-induced premature senescence (SIPS) model of human diploid fibroblasts, replicative senescence model of human diploid fibroblasts, and myoblasts which represent cellular ageing besides the animal model. She has also developed the in vitro model of Alzheimer’s disease carrying the double Swedish/Indiana mutations. She has published more than 100 papers in peer-reviewed international journals and presented more than 150 seminar papers in local and international conferences. She has held many research grants and is currently involved in several research projects.

  • sheng zhang lim, raja affendi raja adli, suzana makpol & eng wee chua.  (2022).  therapeutic monitoring of thiopurine metabolites: validation of an hplc method and preliminary findings from a small cohort of malaysian patients with inflammatory bowel disease.  - sains malaysiana.  1847-1859. 

     

    jen kit tan, sakinah husna abdul razak, hanafi ahmad damanhuri, suzana makpol, wan zurinah wan ngah.  (2022).  metabolomic profiling of middle-aged rat hippocampus.  - asia pacific journal of molecular biology and biotechnology.  85. 

     

    tan jen kit, suzana makpol.  (2022).  comparative study on different extraction methods for lipidomic and metabolomic profiles of chlorella vulgaris.  - 24th medical & health research week.  72. 

     

    amirah abdul rahman, wan zurinah wan ngah, rahman jamal, suzana makpol, roslan harun and norfilza mokhtar.  (2022).  inhibitory mechanism of combined hydroxychavicol with epigallocatechin-3-gallate against glioma cancer cell lines: a transcriptomic analysis.  - frontiers in pharmacology.  1-17. 

     

    tan jen kit;suzana binti makpol;mohd hanafi bin ahmad damanhuri;wan zurinah wan ngah (prof. dr.).  (2022).  understanding the mitochondrial metabolome in hippocampus of rats with cognitive aging.  -

     

    noor azreen masdor, azmawati mohammed nawi, rozita hod, zhiqin wong, suzana makpol and siok fong chin.  (2022).  the link between food environment and colorectal cancer: a systematic review.  - nutrients.  1-18. 

     

    amirah abdul rahman, wan zurinah wan ngah, rahman jamal, suzana makpol, roslan harun and norfilza mokhtar.  (2022).  inhibitory mechanism of combined hydroxychavicol with epigallocatechin-3-gallate against glioma cancer cell lines: a transcriptomic analysis.  - frontiers in pharmacology.  1-17. 

     

    nuraqila mohd murshid, faridah aminullah lubis, suzana makpol.  (2022).  epigenetic changes and its intervention in age-related neurodegenerative diseases.  - cellular and molecular neurobiology.  577-595. 

     

    aslina pahrudin arrozi, siti nur syazwani shukri, nuraqila mohd murshid, ahmad baihaqi ahmad shahzalli, wan zurinah wan ngah, hanafi ahmad damanhuri and suzana makpol.  (2022).  alpha- and gamma-tocopherol modulates the amyloidogenic pathway of amyloid precursor protein in an in vitro model of alzheimer's disease: a transcriptional study.  - frontiers in cellular neuroscience.  1-10. 

     

    aslina pahrudin arrozi, wan zurinah wan ngah, hanafi ahmad damanhuri and suzana makpol.  (2021).  modulatory effects of alpha- and gamma- tocopherol on the mitochondrial respiratory capacity and membrane potential in an in vitro model of alzheimer's disease.  - frontiers in pharmacology.  1-11. 

     

    jen kit tan, sakinah husna abdul razak, nazirah ab rani, nur haleeda hakimi, hanafi ahmad damanhuri, suzana makpol & wan zurinah wan ngah.  (2022).  effects of age and tocotrienol-rich fraction on mitochondrial respiratory complexes in the hippocampus of rats.  - sains malaysiana.  249-259. 

     

    yasmin anum mohd yusof, shailah abdullah, nur fatin nabilah mohd sahardi, wan zurinah wan ngah & suzana makpol.  (2022).  zingiber officinale and piper betle extracts enhanced the chemopreventive effect against colon cancer cells by targeting caspase-mediated apoptosis.  - sains malaysiana.  217-237. 

     

    zaizuhana shahrim; suzana makpol; geok chin tan; nurul aishah muhammad and zafarizal aldrin azizul hasan.  (2022).  topical application of the palm tocotrienol-rich fraction (trf) enhances cutaneous wound healing in type 2 diabetic mice.  - journal of oil palm research.  546-561. 

     

    sheng zhang lim, raja affendi raja adli, suzana makpol & eng wee chua.  (2022).  therapeutic monitoring of thiopurine metabolites: validation of an hplc method and preliminary findings from a small cohort of malaysian patients with inflammatory bowel disease.  - sains malaysiana.  1847-1859. 

     

    pau-ring wong, nur fatin nabilah mohd sahardi, jen-kit tan, kien-hui chua, wan zurinah wan ngah & suzana makpol.  (2022).  characterization of keratinocytes, fibroblasts and melanocytes isolated from human skin using gene markers.  - sains malaysiana.  1425-1436. 

     

    sheng zhang lim, raja affendi raja adli, suzana makpol & eng wee chua.  (2022).  therapeutic monitoring of thiopurine metabolites: validation of an hplc method and preliminary findings from a small cohort of malaysian patients with inflammatory bowel disease.  - sains malaysiana.  1847-1859. 

     

    nuraqila mohd murshid, faridah aminullah lubis, suzana makpol.  (2022).  epigenetic changes and its intervention in age-related neurodegenerative diseases.  - cellular and molecular neurobiology.  577-595. 

     

    jen kit tan, sakinah husna abdul razak, nazirah ab rani, nur haleeda hakimi, hanafi ahmad damanhuri, suzana makpol & wan zurinah wan ngah.  (2022).  effects of age and tocotrienol-rich fraction on mitochondrial respiratory complexes in the hippocampus of rats.  - sains malaysiana.  249-259. 

     

    yasmin anum mohd yusof, shailah abdullah, nur fatin nabilah mohd sahardi, wan zurinah wan ngah & suzana makpol.  (2022).  zingiber officinale and piper betle extracts enhanced the chemopreventive effect against colon cancer cells by targeting caspase-mediated apoptosis.  - sains malaysiana.  217-237. 

     

    amnani aminuddin, pei yuen ng, suzana makpol, chee-onn leong, eng wee chua.  (2022).  rapid changes in mitochondrial dna may participate in the development of cisplatin-resistant oral squamous cell carcinomas.  - malaysian journal of medicine and health sciences.  20. 

     

    amnani aminuddin, eng wee chua, chee-onn leong, suzana makpol, pei yuen ng.  (2021).  potential use of a heat shock protein 90 inhibitor, geldanamycin, in combination therapy with cisplatin in oral squamous cell carcinoma.  - mspp 34th scientific meeting 2021.  61-62. 

     

    yasmin anum mohd yusof, junaidah@maimunah hassan basri, nor ashiken mokti, suhana mohd saad, suhaniza sulaiman, nur sajaratul binti yahya, emey suhana mohd azamai, suzana makpol, wan zurinah wan ngah.  (2011).  chlorella vulgaris : a miracle plant?.  - 4th international conference on modeling, simulation and applied optimization, icmsao 2011. 

     

    tan jen kit, suzana makpol.  (2022).  comparative study on different extraction methods for lipidomic and metabolomic profiles of chlorella vulgaris.  - 24th medical & health research week.  72. 

     

    tan jen kit;suzana binti makpol;mohd hanafi bin ahmad damanhuri;wan zurinah wan ngah (prof. dr.).  (2022).  understanding the mitochondrial metabolome in hippocampus of rats with cognitive aging.  -

     

    suzana binti makpol;mohd rizal bin haji abdul manaf;amilia binti aminuddin;norwahidah binti abdul karim;nur fathiah binti abdul sani;tan jen kit.  (2022).  ginger extract (zingiber officinale) for the promotion of muscle regeneration in elderly population.  -

     

    tan jen kit & suzana makpol.  (2022).  effects of storage time and antioxidant additive on lipid extract from plasma and tissue.  - 46th annual conference of the malaysian society for biochemistry and molecular biology 2022 (msbmb46).  95. 

     

    azraul mumtazah razak, siti nor asyikin zakaria, nur fathiah abdul sani, nur haleeda hakimi, mazlina mohd said, tan jen kit, gan han kwang, mariam firdhaus mad nordin and suzana makpol.  (2022).  evaluation of yield and antioxidant properties of subcritical water extraction of soil and soilless zingiber officinale roscoe bioactive compounds and its anti-inflammatory and antioxidant activities in an ageing animal model.  - international conference on food science and nutrition 2022 "future food: emerging trends, health and diversity".  95.