pensyarah universiti
jabatan sains biologi & bioteknologi
hisham@ukm.edu.my
This research explores alternative sources of stem cells in blood and dental pulp tissue, their potential applications, and the development of biomarkers for various purposes. The findings hold promise for advancing stem cell research and potentially reducing orthodontic treatment time. Notably, dental pulp stem cells as compared to peripheral blood stem cells displayed a higher tendency to become nerve compared to bone cells and cartilage cells. Additionally, studies identified enzyme activity profiles in blood and saliva as potential biomarkers for monitoring bone cell development, tooth movement, and orthodontic treatment progress. Moreover, new, safer methods for cytotoxicity analysis were developed using these stem cells, replacing commonly used cancer cell lines. Beyond these research contributions, also produces numerous publications, awards, and students mentored. Overall, it demonstrates significant potential for advancements in stem cell applications, diagnostics, and potentially improving orthodontic treatment efficiency.
shahrul hisham zainal ariffin, ameedtri tha wip sripraphan, siti nur zahidah zahari, rus dina rus din, intan zarina zainol abidin. (2024). penentuan kumpulan haplo manusia pada gen mt-nd2 dna mitokondria. - simposium biologi kebangsaan ke-10 2023. 6-10.
jun hong steven tan, farinawati yazid, nurfathiha abu kasim, shahrul hisham zainal ariffin, rohaya megat abdul wahab. (2024). a newly developed kit for dental apical root resorption detection: efficacy and acceptability. - bmc oral health. 1-9.
intan zarina zainol abidin, anis nabilah johari, zaidah zainal ariffin, muhammad dain yazid, herryawan ryadi eziwar dyari, shahrul hisham zainal ariffin. (2023). cytotoxic and osteoblast differentiation induction properties of crude polar extract of piper sarmentosum leaves. - journal of tropical life science. 231-238.
intan zarina zainol abidin, anis nabilah johari, muhammad dain yazid, zaidah zainal ariffin, herryawan ryadi eziwar dyari, shahrul hisham zainal ariffin. (2023). osteogenic potential and bioactive profiles of piper sarmentosum ethanolic extract-treated stem cells. - pharmaceuticals. 1-15.
shahrul hisham, z.a., ameedtri, t., siti nur zahidah, z., rus dina, r.d., intan zarina, z.a.. (2023). penentuan kumpulan haplo manusia pada gen mt-nd2 dna mitokondria. - simposium biologi kebangsaan 2023. 120.
jun hong steven tan, farinawati yazid, nurfathiha abu kasim, shahrul hisham zainal ariffin, rohaya megat abdul wahab. (2024). a newly developed kit for dental apical root resorption detection: efficacy and acceptability. - bmc oral health. 1-9.
intan zarina zainol abidin, anis nabilah johari, muhammad dain yazid, zaidah zainal ariffin, herryawan ryadi eziwar dyari, shahrul hisham zainal ariffin. (2023). osteogenic potential and bioactive profiles of piper sarmentosum ethanolic extract-treated stem cells. - pharmaceuticals. 1-15.
milton hongli tsai, rohaya megat abdul wahab, shahrul hisham zainal ariffin, fazren azmi, farinawati yazid. (2023). enhanced osteogenesis potential of mg-63 cells through sustained delivery of vegf via liposomal hydrogel. - gels. 1-17.
nor idayu a. rahman, chung liang lam, nadiah sulaiman, nur atiqah haizum abdullah, fazlina nordin, shahrul hisham zainal ariffin, muhammad dain yazid. (2023). pax7, a key for myogenesis modulation in muscular dystrophies through multiple signaling pathways: a systematic review. - international journal of molecular sciences. 1-21.
nur atmaliya luchman, rohaya megat abdul wahab, shahrul hisham zainal ariffin, nurrul shaqinah nasruddin, seng fong lau, farinawati yazid. (2022). comparison between hydroxyapatite and polycaprolactone in inducing osteogenic differentiation and augmenting maxillary bone regeneration in rats. - peerj. 1-29.
intan zarina zainol abidin, thanaletchumi manogaran, rohaya megat abdul wahab, saiful anuar karsani, muhammad dain yazid, farinawati yazid, zaidah zainal ariffin, anis nabilah johari, shahrul hisham zainal ariffin. (2023). label-free quantitative proteomic analysis of ascorbic acid-induced differentially expressed osteoblast-related proteins in dental pulp stem cells from deciduous and permanent teeth. - current stem cell research & therapy. 417-428.
shahrul hisham zainal ariffin, rohaya megat abdul wahab, thanaletchumi manogaran, farinawati yazid, siti nur zahidah zahari, rus dina rus din, intan zarina zainol abidin. (2023). protein rembesan sel stem pulpa gigi susu manusia (shed) semasa pembezaan kepada sel osteoblas. - sains malaysiana. 1771-1783.
intan zarina zainol abidin; thanaletchumi manogaran; rohaya megat abdul wahab; farinawati yazid; shahrul hisham zainal ariffin. (2022). a comparative analysis of ascorbic acid-induced cytotoxicity and differentiation between shed and dpsc. - current stem cell research and therapy. 576-588.
steven tan jun hong, farinawati yazid, nurfathiha abu kasim, shahrul hisham zainal ariffin, rohaya megat abdul wahab. (2022). orthodontic induced inflammatory root resorption the process involved and its management: a review of literature. - sains malaysiana. 3371-3381.
nur hanina izzati khairol mokhtar, ainulkhir hussin, aidil abdul hamid, shahrul hisham zainal ariffin, muhammad ashraf shahidan. (2022). systematic optimisation of a microtiter assay using sialic-acid specific lectins for glycoprofiling. - combinatorial chemistry & high throughput screening. 1507-1517.
jun hong steven tan, farinawati yazid, nurfathiha abu kasim, shahrul hisham zainal ariffin, rohaya megat abdul wahab. (2024). a newly developed kit for dental apical root resorption detection: efficacy and acceptability. - bmc oral health. 1-9.
intan zarina zainol abidin, anis nabilah johari, muhammad dain yazid, zaidah zainal ariffin, herryawan ryadi eziwar dyari, shahrul hisham zainal ariffin. (2023). osteogenic potential and bioactive profiles of piper sarmentosum ethanolic extract-treated stem cells. - pharmaceuticals. 1-15.
intan zarina zainol abidin, thanaletchumi manogaran, rohaya megat abdul wahab, saiful anuar karsani, muhammad dain yazid, farinawati yazid, zaidah zainal ariffin, anis nabilah johari, shahrul hisham zainal ariffin. (2023). label-free quantitative proteomic analysis of ascorbic acid-induced differentially expressed osteoblast-related proteins in dental pulp stem cells from deciduous and permanent teeth. - current stem cell research & therapy. 417-428.
shahrul hisham zainal ariffin, rohaya megat abdul wahab, thanaletchumi manogaran, farinawati yazid, siti nur zahidah zahari, rus dina rus din, intan zarina zainol abidin. (2023). protein rembesan sel stem pulpa gigi susu manusia (shed) semasa pembezaan kepada sel osteoblas. - sains malaysiana. 1771-1783.
milton hongli tsai, rohaya megat abdul wahab, shahrul hisham zainal ariffin, fazren azmi, farinawati yazid. (2023). enhanced osteogenesis potential of mg-63 cells through sustained delivery of vegf via liposomal hydrogel. - gels. 1-17.
farinawati yazid, mohd norzaliman mohd zain, zalhan md yusof, fairul syazwani hj. ghazali, siti aisyah zulkifli, najah mohd nadri, shahrul hisham zainal ariffin and rohaya megat abdul wahab. (2020). caries detection analysis in human saliva alpha amylase. - the 2nd international conference on advance photonics and electronic (incape 2019). 1-7.
m.n.m. zain , z.m. yusof , f. yazid , a. ashari , k.s.h. wong , w.j. lee , k.f. tan , s.h.z. ariffin and r.m.a wahab. (2020). absorption spectrum analysis of dentine sialophosphoprotein (dspp) in orthodontic patient. - the 2nd international conference on applied photonics and electronics 2019 (incape 2019) aip conference proceedings. 1-6.
farah amirah mohd nasri, rohaya megat abdul wahab, saiful anuar karsani, and shahrul hisham zainal ariffin. (2016). differences of protein profile before and after orthodontic treatment. - the 2016 ukm fst postgraduate colloquium, aip conference proceeding. 1-4.
shahrul hisham zainal ariffin, thanaletchumi manogaran, intan zarina zainol abidin, sahidan senafi, rohaya megat abdul wahab. (2016). isolation and morphology of stem cells from deciduous tooth (shed) and human dental pulp stem cells (hdpsc). - the 2016 ukm fst postgraduate colloquium, aip conference proceeding. 1-5.
zulham yamamoto, ikmal mohamad jaafar, rohaya m. a. w., intan zarina zainol abidin, sahidan senafi, zaidah zainal ariffin and shahrul hisham zainal ariffin. (2013). orthodontic treatment effects on inflammatory marker profiles in saliva before and after 2 archwire changes. - aip conference proceeding-ukm fst postgraduate colloqium. .
rus dina rus din, shahrul hisham zainal ariffin. (2022). tulang purba kapal karam wanli. - . 113.
intan zarina zainol abidin, puteri haslin nadya hasbullah, shahrul hisham zainal ariffin. (2018). siri penyelidikan biosains dan bioteknologi 2018. - . 4.
rus dina rus din, nursyafiqah zafira mahyasi, rohaya megat abdul wahab, shahrul hisham zainal ariffin. (2018). siri penyelidikan biosains dan bioteknologi 2018. - . 4.
shahrul hisham zainal ariffin, rus dina rus din & rohaya megat abdul wahab. (2018). masyarakat protosejarah pulau kelumpang. - . 112.
shahrul hisham zainal ariffin. (2017). penerokaan sel stem untuk kelestarian kehidupan. - . 85.
intan zarina zainol abidin, puteri haslin nadya hasbullah, shahrul hisham zainal ariffin. (2018). siri penyelidikan biosains dan bioteknologi 2018. - . 4.
rus dina rus din, nursyafiqah zafira mahyasi, rohaya megat abdul wahab, shahrul hisham zainal ariffin. (2018). siri penyelidikan biosains dan bioteknologi 2018. - . 4.
rohaya megat abdul wahab, zulham yamamoto, intan zarina zainol abidin & shahrul hisham zainal ariffin. (2017). enzymes and their application. - . 16.
nurnabiha syifaa nasir, muniandy ramansurvey & shahrul hisham zainal ariffin. (2017). siri penyelidikan biosains dan bioteknologi 2017. - . 3.
shahrul hisham zainal ariffin, nur akmal mohamed rozali, intan zarina zainol abidin & rohaya megat abdul wahab. (2017). enzymes and their application. - . 9.
rus dina rus din, shahrul hisham zainal ariffin. (2022). tulang purba kapal karam wanli. - . 113.
shahrul hisham zainal ariffin, rus dina rus din & rohaya megat abdul wahab. (2018). masyarakat protosejarah pulau kelumpang. - . 112.
shahrul hisham zainal ariffin. (2017). penerokaan sel stem untuk kelestarian kehidupan. - . 85.
shabnam kermani, shahrul hisham zainal ariffin, rohaya megat abdul wahab. (2014). dental pulp as a new source of stem cells. - . 67.
shahrul hisham zainal ariffin, rohaya megat abdul wahab & intan zarina zainol abidin. (2011). bioteknologi perubatan: sejarah dan pengenalan. - . 101.
shahrul hisham zainal ariffin, rohaya megat abdul wahab. (2023). rawatan menggunakan sel stem. - persatuan kakitangan akademik ukm. 1.
shahrul hisham, z.a., ameedtri, t., siti nur zahidah, z., rus dina, r.d., intan zarina, z.a.. (2023). penentuan kumpulan haplo manusia pada gen mt-nd2 dna mitokondria. - simposium biologi kebangsaan 2023. 120.
muhammad da`in bin yazid;ruszymah binti haji idrus;shahrul hisham bin zainal ariffin;mohd fauzi bin mh busra;nadiah binti sulaiman. (2023). elucidating the correlation between pax7 regulation and mtorc2 signalling in human duchenne muscular dystrophy skeletal muscle cells. - . .
intan zarina zainol abidin, anis nabilah johari, zaidah zainal ariffin, shahrul hisham zainal ariffin. (2022). cytotoxicity and osteoblasts differentiation effects of piper sarmentosum ethyl acetate extract. - the 4th international conference on biosciences and medical engineering. 42.
intan zarina zainol abidin, anis nabilah johari, zaidah zainal ariffin, shahrul hisham zainal ariffin. (2022). the 4th international conference on biosciences and medical engineering. - piper sarmentosum hexane extract induced osteoblasts differentiation of peripheral blood stem cells. 93.
Geran / Grant | Kolaborator / Collaborator | Status |
---|---|---|
DENTAL ROOT RESORPTION DIAGNOSTIC KIT COMMERCIAL PRODUCTION FOR CLINICAL READY MARKET | vivantis technologies sdn bhd. | 74.7% (2023-11-01 sehingga 2025-04-30) |
UNRAVELLING SUBCELLULAR DYNAMICS OF RICTOR FOR ACTIN REMODELLING IN DUCHENNE MUSCULAR DYSTROPHY (DMD) | ming medical services sdn bhd | 60.1% (2023-10-01 sehingga 2025-09-30) |
UNRAVELLING SUBCELLULAR DYNAMICS OF RICTOR FOR ACTIN REMODELLING IN DUCHENNE MUSCULAR DYSTROPHY (DMD) | malaysian rare disorders society (mrds) | 60.1% (2023-10-01 sehingga 2025-09-30) |
IN-VITRO EVALUATION OF EXOSOME-HYALURONIC ACID SYNERGY IN ORAL WOUND HEALING | wari technologies sdn. bhd. | 5.8% (2024-11-01 sehingga 2026-10-31) |