prof. dr. norfilza mohd mokhtar

pensyarah perubatan

jabatan fisiologi

 norfilza@ppukm.ukm.edu.my



   Biografi/ Biography :

  • Norfilza Mohd Mokhtar is currently the Professor of Genome Medicine at the Department of Physiology. She was the coordinator for the International Program for the Faculty of Medicine. She received her first degree in Doctor of Medicine from the Universiti Sains Malaysia. She underwent molecular biology training under the mentorship of Professor Stephen Charnock Jones and Professor Stephen Smith from the Department of Obstetrics & Gynaecology, University of Cambridge, United Kingdom in 2001 till 2005. She was the President of Malaysian Society of Pharmacology & Physiology from 2019-2020. Her research was on the regulation of macrophage inflammatory protein 2 gamma by steroids in endometrium. She was elected as the Fellow of the Cambridge Commonwealth Trust as well as the life member of Lucy Cavendish College, Cambridge. Her research projects focusing on genomics, epigenomics, transcriptomics and metagenomics aspects on multiple diseases including colorectal cancer, inflammatory bowel disease, colitis associated cancer, and irritable bowel syndrome. Her translational project is on application of MYHealth smartband on the monitoring one`s health in preventing noncommunicable diseases. Her latest venture is on environmental contamination including microplastics on inflammation related diseases.

  • xin hui k, chun wie c, abdul malik talha, koshy philip, cindy shuan ju teh, adib mat isa, ms wong, deborah chia hsin chew, z. wong, ns jusoh, nm mohamed maksum, norfilza m mokhtar, h abdul majid, raja affendi raja ali, yeong yeh lee, sanjiv mahadeva.  (2023).  the impact of diet and ethnicity on gut microbiota variation in irritable bowel syndrome: a multi-center study.  - journal of gastroenterology and hepatology.  1259-1268. 

     

    hooi leng ser, siu jung au yong, mohamad nasir shafiee, norfilza mohd mokhtar, raja affendi raja ali.  (2023).  current updates on the role of microbiome in endometriosis: a narrative review.  - microorganisms.  1-28. 

     

    nor hamizah shafiee, nurul huda razalli, mohd razif shahril, khairul najmi muhammad nawawi, norfilza mohd mokhtar, ainaa almardhiyah abd rashid, lydiatul shima ashari, hamid jan jan mohamed, raja affendi raja ali.  (2023).  dietary inflammatory index, obesity, and the incidence of colorectal cancer: findings from a hospital-based case-control study in malaysia.  - nutrients.  1-17. 

     

    nor hafiza sayuti, khairul najmi muhammad nawawi, jo aan goon, norfilza mohd mokhtar, suzana makpol & jen kit tan.  (2023).  a review of the effects of fucoxanthin on nafld.  - nutrients.  1-12. 

     

    nurul nadirah razali, raja affendi raja ali, khairul najmi muhammad nawawi, azyani yahaya, norshafila diana mohd rathi, norfilza mohd mokhtar.  (2023).  roles of phosphatidylinositol-3-kinases signaling pathway in inflammation-related cancer: impact of rs10889677 variant and buparlisib in colitis-associated cancer.  - world journal of gastroenterology.  5543-5556. 

     

    xin hui k, chun wie c, abdul malik talha, koshy philip, cindy shuan ju teh, adib mat isa, ms wong, deborah chia hsin chew, z. wong, ns jusoh, nm mohamed maksum, norfilza m mokhtar, h abdul majid, raja affendi raja ali, yeong yeh lee, sanjiv mahadeva.  (2023).  the impact of diet and ethnicity on gut microbiota variation in irritable bowel syndrome: a multi-center study.  - journal of gastroenterology and hepatology.  1259-1268. 

     

    nor hamizah shafiee, nurul huda razalli, mohd razif shahril, khairul najmi muhammad nawawi, norfilza mohd mokhtar, ainaa almardhiyah abd rashid, lydiatul shima ashari, hamid jan jan mohamed, raja affendi raja ali.  (2023).  dietary inflammatory index, obesity, and the incidence of colorectal cancer: findings from a hospital-based case-control study in malaysia.  - nutrients.  1-17. 

     

    nurainina ayob, khairul najmi muhammad nawawi, mohamad hizami mohamad nor, raja affendi raja ali, hajar fauzan ahmad, seok fang oon and norfilza mohd mokhtar.  (2023).  the effects of probiotics on small intestinal microbiota composition, inflammatory cytokines and intestinal permeability in patients with non-alcoholic fatty liver disease.  - biomedicines.  1-21. 

     

    hooi leng ser, siu jung au yong, mohamad nasir shafiee, norfilza mohd mokhtar, raja affendi raja ali.  (2023).  current updates on the role of microbiome in endometriosis: a narrative review.  - microorganisms.  1-28. 

     

    nur syakirah othman, amilia aminuddin, shahidee zainal abidin, saiful effendi syafruddin, mohd faizal ahmad, norfilza mohd mokhtar, jaya kumar, adila a. hamid, azizah ugusman.  (2023).  profiling of differentially expressed micrornas in human umbilical vein endothelial cells exposed to hyperglycemia via rna sequencing.  - life.  1-16. 

     

    norhazlina a wahab, huria d dardar, rosna yunus, zulkifli m zainudin, norfilza m mokhtar.  (2022).  silencing of hepsin and inosine 5-monophosphate dehydrogenase 2 by sirna reduces prostate cancer cells proliferation.  - malaysian journal of pathology.  29-38. 

     

    nurul hayati mohamad zainal, nor azlin mohamed ismail & norfilza mohd mokhtar.  (2022).  low methylation of matrix metalloproteinase 1 (mmp1) is associated with preterm labour in malaysian mothers.  - sains malaysiana.  2033-2046. 

     

    hanisah abdul hamid, wei yen kong, norwahidah abdul karim, meng hsien yong, norfilza mohd mokhtar, norshamsiah md din.  (2022).  diabetic nephropathy with and without retinopathy: comparison between urine and serum vascular endothelial growth factor.  - international journal of diabetes in developing countries.  108-115. 

     

    norfilza m. mokhtar, norhayati md. jaafar, ereena alfian, norshafila diana mohd rathi, r. abdul rani, raja affendi raja ali.  (2021).  clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with lactobacillus-containing cultured milk drink.  - acta gastro-enterologica belgica.  585-591. 

     

    allia najmie muhammad yusuf, raja affendi raja ali, khairul najmi muhammad nawawi, norfilza mohd mokhtar.  (2020).  potential biomarkers in nash-induced liver cirrhosis with hepatocellular carcinoma: a preliminary work on roles of exosomal mir-182, mir-301a, and mir-373.  - malaysian journal of pathology.  377-384. 

     

    nor hafiza sayuti, khairul najmi muhammad nawawi, jo aan goon, norfilza mohd mokhtar, suzana makpol & jen kit tan.  (2023).  a review of the effects of fucoxanthin on nafld.  - nutrients.  1-12. 

     

    nor hamizah shafiee, nurul huda razalli, mohd razif shahril, khairul najmi muhammad nawawi, norfilza mohd mokhtar, ainaa almardhiyah abd rashid, lydiatul shima ashari, hamid jan jan mohamed, raja affendi raja ali.  (2023).  dietary inflammatory index, obesity, and the incidence of colorectal cancer: findings from a hospital-based case-control study in malaysia.  - nutrients.  1-17. 

     

    nur syakirah othman, amilia aminuddin, shahidee zainal abidin, saiful effendi syafruddin, mohd faizal ahmad, norfilza mohd mokhtar, jaya kumar, adila a. hamid, azizah ugusman.  (2023).  profiling of differentially expressed micrornas in human umbilical vein endothelial cells exposed to hyperglycemia via rna sequencing.  - life.  1-16. 

     

    nurainina ayob, khairul najmi muhammad nawawi, mohamad hizami mohamad nor, raja affendi raja ali, hajar fauzan ahmad, seok fang oon and norfilza mohd mokhtar.  (2023).  the effects of probiotics on small intestinal microbiota composition, inflammatory cytokines and intestinal permeability in patients with non-alcoholic fatty liver disease.  - biomedicines.  1-21. 

     

    xin hui k, chun wie c, abdul malik talha, koshy philip, cindy shuan ju teh, adib mat isa, ms wong, deborah chia hsin chew, z. wong, ns jusoh, nm mohamed maksum, norfilza m mokhtar, h abdul majid, raja affendi raja ali, yeong yeh lee, sanjiv mahadeva.  (2023).  the impact of diet and ethnicity on gut microbiota variation in irritable bowel syndrome: a multi-center study.  - journal of gastroenterology and hepatology.  1259-1268. 

     

    norfilza m. mokhtar, nor azian abdul murad, then sue mian and rahman jamal.  (2013).  oncogenomics and cancer proteomics - novel approaches in biomarkers discovery and therapeutic targets in cancer.  - 1-48. 

     

    m.h. rajikin, n. mokhtar, a. chatterjee & y.s. kamsani.  (2013).  tocotrienols: vitamin e beyond tocopherols.  - 323-331 (24). 

     

    prof. ir. dr. shahrir abdullah.  (2012).  garis panduan penyediaan dokumen program pengajian universiti kebangsaan malaysia.  - 110. 

     

    m.h. rajikin, n. mokhtar, a. chatterjee & y.s. kamsani.  (2013).  tocotrienols: vitamin e beyond tocopherols.  - 323-331 (24). 

     

    norfilza m. mokhtar, nor azian abdul murad, then sue mian and rahman jamal.  (2013).  oncogenomics and cancer proteomics - novel approaches in biomarkers discovery and therapeutic targets in cancer.  - 1-48. 

     

    prof. ir. dr. shahrir abdullah.  (2012).  garis panduan penyediaan dokumen program pengajian universiti kebangsaan malaysia.  - 110. 

     

    norfilza mohd mokhtar, norhazlina abdul wahab.  (2009).  pembiakan pengekal zuriat.  - 48. 

     

    norhazlina abdul wahab, norfilza mohd mokhtar.  (2008).  otot dan rangka: penggerak kehidupan.  - 48. 

     

    khairul najmi bin muhammad nawawi;norfilza mohd mokhtar;wong zhiqin;raja affendi bin raja ali.  (2023).  revealing fecal short chain fatty acids as gut microbiota-derived biomarker in non-alcoholic fatty liver disease.  -

     

    norfilza mohd mokhtar;norhazlina binti abdul wahab;norhayati binti ibrahim;jaya kumar a/l murthy;khairul najmi bin muhammad nawawi.  (2023).  targeting gut-microbiome-brain axis: probiotic have antidepression-like effects and reverse the impact of chronic stress in rats.  -

     

    adila binti a. hamid;norfilza mohd mokhtar;azizah binti ugusman;mohd faizal bin ahmad.  (2023).  unraveling the role of mir-222 and mir-126 in human umbilical vein endothelial cell (huvec) isolated from pregnancy-induced hypertension (pih) mother to assess the risk of hypertension in the baby..  -

     

    nirmala @ chandralega a/p kampan;mohd hashim bin omar;norfilza mohd mokhtar;mohamad nasir bin shafiee;nor haslinda binti abd aziz;chew kah teik;reena rahayu md zin.  (2023).  detection of inflammatory and immunosuppressive molecular alteration signatures to prevent disease relapse in women with high-grade serous ovarian cancer. .  -

     

    shairah abdul razak, zubaidah hasain, norfilza mohd mokhtar, mohd aftar abu bakar, raja affendi raja ali.  (2023).  impact of probiotics on gut microbiome in postpartum women with history of gestational diabetes mellitus(gdm): comprehensive analysis using predicting modelling towards optimal clinical care.  - 1-7.