Biografi/ Biography :
My research is primarily directed at understanding molecular function regulation by exploring the mechanistic atomic level interactions that affect function and/or effect molecular level switching as well as the associated regulatory pathways. To accomplish this, my research group studies the structure, function and evolution of biological macromolecules to compare how the atomic level differences can result in different functions by effecting regulatory or mechanistic changes. We source our data from public repositories such as GenBank and the Protein Data Bank as well as by generating internal data such as genome sequences, transcriptome sequences and methylome sequences from specific experiments. The approaches employed in exploring and investigating these datasets primarily involve bioinformatics, computational biology and genomics but also extend to structural biology (mainly X-ray crystallography), synthetic biology and systems biology. The insights revealed from these investigations can provide clues as to how molecular level regulation and responses in living systems are carried out that eventually lead to an organism’s capacity to adapt to extreme (ie. extremophiles) or diverse environments (ie. such as a bacterial pathogen or parasite adapting to a host) as well as the discovery of novel factors associated with pathogenesis (toxins and pathogenesis/virulence regulation systems). Our understanding of the atomic level interactions that define specific biological mechanisms have led to the development of applications for drug repositioning and tools for the synthetic design of nucleic acid self-assembling structures.
ahmad-kamal ghazali, mohd firdaus-raih, asqwin uthaya kumar, wei-kang lee, chee-choong hoh, sheila nathan. (2023). transitioning from soil to host: comparative transcriptome analysis reveals the burkholderia pseudomallei response to different niches. - microbiology spectrum. 1-21.
mursyidah, a.-k., hafizzudin-fedeli, m., nor muhammad, n.a., latiff, a., firdaus-raih, m., wan, k.-l.. (2023). dissecting the biology of rafflesia species: current progress and future directions made possible with high-throughput sequencing data. - plant and cell physiology. 368-377.
naif h m al-hardan, muhammad azmi abdul hamid, azman jalar, mohd firdaus-raih. (2023). unleashing the potential of gallium oxide: a paradigm shift in optoelectronic applications for image sensing and neuromorphic computing applications. - materials today physics. 1-24.
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2023). characterisation of the beca-r gene cluster involved in the synthesis of burkholderia pseudomallei biofilm exopolysaccharide. - "joint 11th asia oceania human proteome organization (aohupo) and 7th asia oceania agricultural proteomics organization (aoapo) congress". 309.
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2023). biofilm signaling, composition and regulation in burkholderia pseudomallei. - journal of microbiology and biotechnology. 15-27.
sofiyah shaibullah; nurshahirah shuhaimi; de-sheng ker; nurhikmah mohd-sharif; kok lian ho; aik-hong the; jitka waterman; thean-hock tang; rui-rui wong; sheila nathan; rahmah mohamed; min jia ng; shin-yee fung; mohd firdaus-raih; chyan leong ng; et. al. (2023). structural and functional analyses of burkholderia pseudomallei bpsl1038 reveal a cas-2/vapd nuclease sub-family. - communications biology. 1-15.
ahmad-kamal ghazali, mohd firdaus-raih, asqwin uthaya kumar, wei-kang lee, chee-choong hoh, sheila nathan. (2023). transitioning from soil to host: comparative transcriptome analysis reveals the burkholderia pseudomallei response to different niches. - microbiology spectrum. 1-21.
naif h m al-hardan, muhammad azmi abdul hamid, azman jalar, mohd firdaus-raih. (2023). unleashing the potential of gallium oxide: a paradigm shift in optoelectronic applications for image sensing and neuromorphic computing applications. - materials today physics. 1-24.
mursyidah, a.-k., hafizzudin-fedeli, m., nor muhammad, n.a., latiff, a., firdaus-raih, m., wan, k.-l.. (2023). dissecting the biology of rafflesia species: current progress and future directions made possible with high-throughput sequencing data. - plant and cell physiology. 368-377.
nur afiqah shalihin muhamad ismail, su hui yap, mohamad ariff mohamad yussoff, nor azlan nor muhammad, mohd firdaus-raih, doris huai xia quay. (2023). modeling and computational characterization of a xanthomonas sp. hypothetical protein identifies a remote ortholog of burkholderia lethal factor 1. - journal of biomolecular structure and dynamics. 1-14.
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2023). biofilm signaling, composition and regulation in burkholderia pseudomallei. - journal of microbiology and biotechnology. 15-27.
siti asmaa mat jusoh, danesh thangeswaran, muhammad syahir hakimi mohd hazli, mohd firdaus raih, nurulasma abdullah, shaharum shamsuddin. (2022). construction of multi-epitopes vaccine candidate against sars-cov-2 d614g variant. - sains malaysiana. 2985-2997.
hafizzudin-fedeli, m., abu-bakar, m.-f., mat-isa, m.-n., latiff, a., firdaus-raih, m., wan, k.-l.. (2022). characterisation of tetrastigma rafflesiae mitochondrial genes and assessment of their potential as sequence markers. - sains malaysiana. 2435-2447.
noor munyati othman, sri d. appasamy, nadzirah damiri, reeki emrizal, norfarrah mohamed alipiah, effirul ikhwan ramlan, mohd firdaus raih. (2021). regulation of glycine cleavage and detoxification by a highly conserved glycine riboswitch in burkholderia spp. - current microbiology. 2943-2955.
xin-wei lee, su datt lam, mohd firdaus-raih, kiew-lian wan. (2020). molecular characterisation of eimeria tenella porin, a potential anticoccidial drug target. - sains malaysiana. 755-764.
naif h m al-hardan, muhammad azmi abdul hamid, azman jalar, mohd firdaus-raih. (2023). unleashing the potential of gallium oxide: a paradigm shift in optoelectronic applications for image sensing and neuromorphic computing applications. - materials today physics. 1-24.
nur afiqah shalihin muhamad ismail, su hui yap, mohamad ariff mohamad yussoff, nor azlan nor muhammad, mohd firdaus-raih, doris huai xia quay. (2023). modeling and computational characterization of a xanthomonas sp. hypothetical protein identifies a remote ortholog of burkholderia lethal factor 1. - journal of biomolecular structure and dynamics. 1-14.
mursyidah, a.-k., hafizzudin-fedeli, m., nor muhammad, n.a., latiff, a., firdaus-raih, m., wan, k.-l.. (2023). dissecting the biology of rafflesia species: current progress and future directions made possible with high-throughput sequencing data. - plant and cell physiology. 368-377.
sofiyah shaibullah; nurshahirah shuhaimi; de-sheng ker; nurhikmah mohd-sharif; kok lian ho; aik-hong the; jitka waterman; thean-hock tang; rui-rui wong; sheila nathan; rahmah mohamed; min jia ng; shin-yee fung; mohd firdaus-raih; chyan leong ng; et. al. (2023). structural and functional analyses of burkholderia pseudomallei bpsl1038 reveal a cas-2/vapd nuclease sub-family. - communications biology. 1-15.
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2023). biofilm signaling, composition and regulation in burkholderia pseudomallei. - journal of microbiology and biotechnology. 15-27.
siuk-mun ng, xin-wei lee, kiew-lian wan & mohd firdaus-raih. (2015). comparative differential gene expression analysis of nucleus-encoded proteins for rafflesia cantleyi against arabidopsis thaliana. - the 2015 ukm fst postgraduate colloquium. 030020(1-6).
intan azlinda ramlee, mohd firdaus-raih & kiew-lian wan. (2015). identification and characterization of secreted proteins in eimeria tenella. - aip conference proceedings. 030023.
noor munyati othman, ahmad luqman abdul fatah, mohd al akmarul fizree bin md piji, effirul ikhwan ramlan and mohd firdaus raih. (2015). identification and cloning of four riboswitches from burkholderia pseudomallei strain k96243. - the 2015 ukm fst postgraduate colloquium. 1-5.
nur syamimi yusoff, nadzirah damiri, mohd firdaus-raih. (2014). identification of the conserved hypothetical protein bpsl0317 in burkholderia pseudomallei k96243. - aip conference proceeding - the 2014 ukm fst postgraduate colloquium. 544-548.
faridah hani mohamed salleh, suhaila zainudin,mohd firdaus raih. (2021). model regresi untuk pembinaan semula rangkaian pengawal atur gen. - . 162.
shuhaila mat-sharani, doris hx quay, chyan l ng & mohd firdaus-raih. (2019). encyclopedia of bioinformatics and computational biology. - . 7.
nur sa ghani, shandar ahmad, mohd firdaus-raih. (2018). encyclopedia of bioinformatics and computational biology. - . 9.
munyati othman, siuk m ng, mohd firdaus-raih. (2018). encyclopedia of bioinformatics and computational biology. - . 5.
suhaila sulaiman, nur s yusoff, ng s mun, haslina makmur, mohd firdaus-raih. (2018). encyclopedia of bioinformatics and computational biology. - . 11.
chyan leong ng & mohd firdaus-raih. (2019). encyclopedia of bioinformatics and computational biology. - . 14.
shuhaila mat-sharani, doris hx quay, chyan l ng & mohd firdaus-raih. (2019). encyclopedia of bioinformatics and computational biology. - . 7.
munyati othman, siuk m ng, mohd firdaus-raih. (2018). encyclopedia of bioinformatics and computational biology. - . 5.
mohd firdaus-raih, nur syatila abdul ghani. (2018). encyclopedia of bioinformatics and computational biology. - . 10.
nur sa ghani, shandar ahmad, mohd firdaus-raih. (2018). encyclopedia of bioinformatics and computational biology. - . 9.
faridah hani mohamed salleh, suhaila zainudin,mohd firdaus raih. (2021). model regresi untuk pembinaan semula rangkaian pengawal atur gen. - . 162.
idayu maarof, mohd firdaus raih. (2021). a consequence of sequence. - . 204.
idayu maarof, mohd firdaus raih. (2016). the doctor is sick. - . 128.
mohd firdaus bin mohd raih;zeti azura binti mohamed hussein;norfarhan binti mohd assa`ad. (2023). computational comparisons of rna 3d base arrangements to identify ligand binding sites in rna structures. - . .
wan kiew lian;mohd firdaus bin mohd raih;ng chyan leong. (2023). insights into life as a single flower via comparative transcriptome analysis. - . .
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2023). characterisation of the beca-r gene cluster involved in the synthesis of burkholderia pseudomallei biofilm exopolysaccharide. - "joint 11th asia oceania human proteome organization (aohupo) and 7th asia oceania agricultural proteomics organization (aoapo) congress". 309.
naif h.m. al-hardan;muhammad azmi bin abdul hamid;mohd firdaus bin mohd raih;lim kar keng. (2023). investigating the effects of post annealing treatment towards the performance of chem-fet titanium oxide sensor for sodium and potassium ion sensing in aqueous solution. - . .
ng chyan leong;sheila nathan;mohd firdaus bin mohd raih. (2023). structural and functional characterization of genes encoding hypothetical proteins but are essential for host infection in burkholderia pseudomallei . - . .