Kluster Kepakaran/ Cluster of Expertise :
Kesihatan dan Perubatan Termaju,
Biografi/ Biography :
Dr. Mohd.Heikal Mohd.Yunus, is a senior medical lecturer in the Department of Physiology, Faculty of Medicine, National University of Malaysia since March 2009. He has been an Associate Research Fellow at the Tissue Engineering Center since 2009. He obtained a Doctor of Medicine (MD) and Master in Medical Science Physiology from the National University of Malaysia under the supervision of Professor Dato ` Dr. Ruszymah Hajj Idrus. He was subsequently awarded a PhD (Pharmacology) specialized in Regenerative Medicine from the same university. His expertise in the field of Regenerative Medicine was recognized when he was appointed as a Working Committee of the Amendment of the Human Tissue Act 1974 by the Ministry of Health Malaysia in 2017. He was also appointed cGMP Laboratory Clinical Trials Coordinator for cell therapy and tissue engineering under the auspices of Centre for Research UKM in 2008 and Chief Clinical Officer at Cell Tissue Technology Sdn. Berhad in 2014 where he was assigned the responsibility of screening patients who were potentially treated using the ‘MyDerm` product and subsequently served as a liaison between the production division and the surgeon. Dr. Mohd Heikal is a specialist in the field of Regenerative Medicine and his research focuses on the areas of skin tissue engineering, tracheal and cartilage tissue. His research focuses on the reconstruction of human tissues through tissue engineering methods from autologous samples where replacement tissue is manufactured using a portion of the patient`s own tissue to treat injuries or defects in parts of the body. He has received various awards both inside and outside the UKM. In 2014, Dr. Mohd. Heikal was selected as the finalist in the final of the Global Innovation through Science and Technology (GIST) initiative’s Technology-Idea (Tech-I) at the Global Entrepreneurship Summit (GES) in Marrakech, Morocco. He was one of 15 participants selected from over 70 countries around the South America, Africa, and Asia. He was also the winner of the
nor amira nabila amir razak, jo aan goon, wan zurinah wan ngah, suzana makpol, nor faeizah ibrahim, nur fathiah abdul sani, kok yong chin, amilia aminuddin, mohd heikal mohd yunus, munirah md mansor. (2026). third interim report for a randomized, double-blinded, placebo-controlled study to evaluate the efficacy of oral supplementation of tocotrienol rich fraction (davoslife e3 complete). - . .
yi ting lee, mohd heikal mohd yunus, rizal abdul rani, chiew yong ng, muhammad dain yazid, azizah ugusman and jia xian law. (2026). bioactive-rich piper sarmentosum aqueous extract mitigates osteoarthritic pathology by enhancing anabolic activity and attenuating no-driven catabolism in human chondrocytes. - biomedicines. 1 - 21.
muhammad tshaqif mohd asri, nurul iman mohd roslizam, fahmiza aishah tasripin, josephine xin ying tan, mohammad arif kamarudin, muhammad nazim othman, mohd heikal mohd yunus. . (2025). impact of prolonged exposure to high energy visible light from digital devices on medical students. - the international e-journal of science, medicine and education (iejsme) . 52 - 52.
li ting kee, jhi biau foo, chee wun how, abdul ghani nur azurah, hong hao chan, mohd heikal mohd yunus, see nguan ng, min hwei ng, jia xian law. (2025). umbilical cord mesenchymal stromal cell-derived small extracellular vesicles modulate skin matrix synthesis and pigmentation. - international journal of nanomedicine. 1561 - 1578.
goon jo aan, amira nabila amir razak, suzana makpol, nor faeizah ibrahim, nur fathiah sani, amilia aminuddin, mohd heikal mohd yunus, chin kok yong, munirah mansor, wan zurinah wan ngah. (2025). second interim report for clinical trial: a randomized, double-blinded, placebo-controlled study to evaluate the efficacy of oral supplementation of tocotrienol rich fraction (davoslife e3 complete). - . .
yi ting lee, mohd heikal mohd yunus, rizal abdul rani, chiew yong ng, muhammad dain yazid, azizah ugusman and jia xian law. (2026). bioactive-rich piper sarmentosum aqueous extract mitigates osteoarthritic pathology by enhancing anabolic activity and attenuating no-driven catabolism in human chondrocytes. - biomedicines. 1 - 21.
li ting kee, jhi biau foo, chee wun how, abdul ghani nur azurah, hong hao chan, mohd heikal mohd yunus, see nguan ng, min hwei ng, jia xian law. (2025). umbilical cord mesenchymal stromal cell-derived small extracellular vesicles modulate skin matrix synthesis and pigmentation. - international journal of nanomedicine. 1561 - 1578.
wafa ali batarfi, mohd heikal mohd yunus, adila a. hamid, manira maarof and rizal abdul rani . (2025). breaking down osteoarthritis: exploring inflammatory and mechanical signaling pathways. - life. 1 - 28.
wafa ali batarfi , mohd heikal mohd yunus, adila a. hamid, yi ting lee, manira maarof . (2024). hydroxytyrosol: a promising therapeutic agent for mitigating inflammation and apoptosis. - pharmaceutics. 1 - 15.
yi ting lee, mohd heikal mohd yunus, muhammad dain yazid and azizah ugusman. (2024). unraveling the path to osteoarthritis management: targeting chondrocyte apoptosis for therapeutic intervention. - frontiers in cell and developmental biology. 1-16.
muhammad najib fathi hassan, muhammad dain yazid, mohd heikal bin mohd yunus, yogeswaran lokanathan, min hwei ng, ruszymah bt hj idrus, yee loong tang, see nguan ng, jia xian law. (2025). comparing the growth kinetics and characteristics of wharton’s jelly derived mesenchymal stem cells expanded using different culture mediums. - cytotechnology. 1 - 16.
adila a hamid, amilia aminuddin, mohd heikal mohd yunus, jaya kumar murthy, chua kien hui and azizah ugusman. (2020). antioxidative and anti-inflammatory activities of polygonum minus: a review of literature. - reviews in cardiovascular medicine. 275-287.
mohd heikal mohd yunus, muhammad abid nordin, haziq aiman kamal bahri. (2020). pathophysiological perspective of osteoarthritis. - medicina-lithuania. 1-13.
mohd heikal mohd yunus, ahmad nazrun shuid, mohd fauzi busra, chua kien hui, norzana abdul ghafar & rizal abd rani. (2019). the effect of stichopus chloronotus aqueous extract on human osteoarthritis articular chondrocytes in three-dimensional collagen type i hydrogel in vitro. - sains malaysiana. 1671-1683.
mohd yunus mohd heikal, shuid ahmad nazrun, kien hui chua, abd ghafar norzana. (2019). stichopus chloronotus aqueous extract as a chondroprotective agent for human chondrocytes isolated from osteoarthitis articular cartilage in vitro. - cytotechnology. 521-537.
yi ting lee, mohd heikal mohd yunus, rizal abdul rani, chiew yong ng, muhammad dain yazid, azizah ugusman and jia xian law. (2026). bioactive-rich piper sarmentosum aqueous extract mitigates osteoarthritic pathology by enhancing anabolic activity and attenuating no-driven catabolism in human chondrocytes. - biomedicines. 1 - 21.
nor amira nabila amir razak, jo aan goon, wan zurinah wan ngah, suzana makpol, mohd hanafi ahmad damanhuri, nor faeizah ibrahim, nur fathiah abdul sani, nuraqila mohd murshid, anis faqihah mohd azizan, kok yong chin, amilia aminuddin, mohd heikal mohd yunus, munirah md mansor , juvenia rui en neo, wei ney yap, hsieu yen loong, yee wei ung. (2025). effectiveness of tocotrienol-rich fraction in older adults: protocol for a randomized, double-blind, placebo-controlled trial. - jmir research protocols. 1 - 18.
wafa ali batarfi, mohd heikal mohd yunus, adila a. hamid, manira maarof and rizal abdul rani . (2025). breaking down osteoarthritis: exploring inflammatory and mechanical signaling pathways. - life. 1 - 28.
muhammad najib fathi hassan, muhammad dain yazid, mohd heikal bin mohd yunus, yogeswaran lokanathan, min hwei ng, ruszymah bt hj idrus, yee loong tang, see nguan ng, jia xian law. (2025). comparing the growth kinetics and characteristics of wharton’s jelly derived mesenchymal stem cells expanded using different culture mediums. - cytotechnology. 1 - 16.
li ting kee, jhi biau foo, chee wun how, abdul ghani nur azurah, hong hao chan, mohd heikal mohd yunus, see nguan ng, min hwei ng, jia xian law. (2025). umbilical cord mesenchymal stromal cell-derived small extracellular vesicles modulate skin matrix synthesis and pigmentation. - international journal of nanomedicine. 1561 - 1578.
ooi kai shen, shafieq haszman, wong yon nie, emilia soidin, nadhirah hesham, mohd fauzi mh busra, mohd heikal mohd yunus. (2021). physico-chemical characterization of bilayer composite palm tree-based nanocellulose as a potential wound dressing. - malaysian society of pharmacology & physiology (mspp) - 34th scientific meeting 2021. 209-210.
najla shakirah ab halim, azizah ugusman, amilia aminuddin, mohd heikal mohd yunus, mohd faizal ahmad,nur najmi mohamad anuar, adila a hamid. (2021). polygonum minus inhibits tumor necrosis factor alpha-induced endothelial cell migration. - malaysian society of pharmacology & physiology (mspp) - 34th scientific meeting 2021, frontiers in pharmacology. 207-208.
juriza i, ruzanna z, harlina hs, rohaizak m, zulkifli z, fauzi ma, m radniwan, m, razif, m heikal, anisah n, nabishah m, lokman s. (2011). outdoor camps experiential learning activities for teamwork and leadership among medical students. - kongres pengajaran dan pembelajaran ukm, 2010; tanjung keling, melaka (procedia social and behavioural sciences). .
yogeswaran lokanathan, angela ng min hwei, mohd heikal mohd yunus, ruszymah haji idrus & daniel lee eng shen. (2024). terapi sel dan sindrom metabolik. - . 61 - 72.
law jia xian, kee li ting, foo jhi biau, how chee wun, nur azurah abdul ghani, chan hong hao, mohd heikal bin mohd yunus, ng see nguan, ng min hwei. (2024). meremajakan kulit menggunakan vesikel ekstrasel terbitan sel stem. - research medicine innovation. .
yogeswaran lokanathan, angela ng min hwei, mohd heikal mohd yunus, ruszymah haji idrus & daniel lee eng shen. (2024). terapi sel dan sindrom metabolik. - . 61 - 72.
mohd heikal mohd yunus nur adelina a. noruddin ruszymah idrus. (2021). rawatan alternatif stenosis trakea melalui kaedah kejuruteraan tisu. - . 89.
mohd heikal mohd yunus. (2020). sumber laut sebagai penawar osteoartritis. - . 100.
mohd heikal mohd yunus, ruszymah bt hj. idrus, aminuddin bin saim. (2020). teknologi kejuruteraan tisu memberi harapan pada pesakit stenosis trakea. - majalah impak siri 1/2020. 6.
nor amira nabila amir razak, jo aan goon, wan zurinah wan ngah, suzana makpol, nor faeizah ibrahim, nur fathiah abdul sani, kok yong chin, amilia aminuddin, mohd heikal mohd yunus, munirah md mansor. (2026). third interim report for a randomized, double-blinded, placebo-controlled study to evaluate the efficacy of oral supplementation of tocotrienol rich fraction (davoslife e3 complete). - . .
profesor dr suzana makpol, prof. emeritus dato’ dr. wan zurinah wan ngah, assoc. prof. dr. goon jo aan, assoc. prof. dr. hanafi damanhuri, dr. norwahidah abdul karim, assoc. prof. dr. chin kok yong, assoc. prof. dr. tan jen kit, dr. amilia aminuddin, dr. munirah md mansor, dr. mohd heikal mohd yunus, ms ung yee wei, dr yap wei ney, ms marianne loong hsieu yen, puan nur fathiah abdul sani. (2025). third progress report on tocotrienol as a senolytic agent: a phase 2 clinical trial. - . .
mohd khairul zain nh, mohd azli sna, makpol s, wan ngah wz, goon ja, damanhuri h, abdul karim n, chin ky, tan jk, aminuddin a, md mansor m, mohd yunus mh, ung yw, yap wn, loong mhy, abdul sani nf. (2025). effects of tocotrienol-rich fraction on dietary intake and body composition: interim findings from a double-blind randomised controlled trial. - 27th medical & health research week 'upholding credibility in an evolving research landscape'. .
goon jo aan, amira nabila amir razak, suzana makpol, nor faeizah ibrahim, nur fathiah sani, amilia aminuddin, mohd heikal mohd yunus, chin kok yong, munirah mansor, wan zurinah wan ngah. (2025). second interim report for clinical trial: a randomized, double-blinded, placebo-controlled study to evaluate the efficacy of oral supplementation of tocotrienol rich fraction (davoslife e3 complete). - . .
mohd azli, s.n.a., mohd khairul zain, n.h., wan ngah, w.z., goon, j.a., damanhuri, h., abdul karim, n., chin, k.y., tan, j.k., aminuddin, a., md mansor, m., mohd yunus, m.h., ung, y.w., yap, w.n., loong, h.y., abdul sani, f., makpol, s.. (2025). effect of body mass index on bone mineral density in middle-aged adults. - postgraduate research conference 2025 . .
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| EVALUATION OF SKIN WOUND HEALING EFFICIENCY USING 3D-BIOPRINTED HYBRID HYALURONIC ACID-GELATIN BIOINKS IN DIABETIC SKIN WOUND MICE MODEL. | 3d gens sdn. bhd. | 98.5% (2024-02-28 sehingga 2026-02-27) |
| EVALUATION OF SKIN WOUND HEALING EFFICIENCY USING 3D-BIOPRINTED HYBRID HYALURONIC ACID-GELATIN BIOINKS IN DIABETIC SKIN WOUND MICE MODEL. | my cytohealth sdn bhd | 98.5% (2024-02-28 sehingga 2026-02-27) |
| TOCOTRIENOL AS A SENOLYTIC AGENT: A PHASE 2 CLINICAL TRIAL | malaysian palm oil board (mpob) | 77.2% (2022-11-29 sehingga 2027-01-30) |
| TOCOTRIENOL AS A SENOLYTIC AGENT: A PHASE 2 CLINICAL TRIAL | davos life science sdn bhd | 77.2% (2022-11-29 sehingga 2027-01-30) |
| ADVANCED PRODUCTION TECHNOLOGY FOR STEM CELL: MASS PRODUCTION WITH BIOREACTOR (PROOF OF CONCEPT) | yakin splendour sdn bhd | 87.5% (2023-01-26 sehingga 2026-07-25) |
BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
Regenerative Medicine/Tissue Enggineering
Pengalaman / Experience : tahun/years(s)
BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
STEM CELL AND TISSUE ENGINEERING
Pengalaman / Experience : 12 tahun/years(s)