prof. madya dr. satirah binti zainalabidin

pensyarah universiti

pusat kajian toksikologi & risiko kesihatan (core)

No. sambungan :  0392897684

No. rasmi:
UKM : 03 8921 5555



   Biografi/ Biography :
  • My area of interest is in cardiovascular physiology and pharmacology. I am involved in few projects to understand the mechanism of cardiovascular injury using animal models such as in isoprenaline-induced and nicotine-induced. I am also interested in studying medicinal plants or bioactive compounds, such as anthocyanin-rich roselle, cardiac glycoside 17beta-neriifolin from Cerbera odollum and S-allylcysteine which is typically found in garlic. The main laboratory technique that I use is isolated perfused heart by Langendorff apparatus, the only active kind of cardiovascular research in Malaysia.

  • khairul anwar zarkasi, satirah zainal abidin, tan jen kit, nur haleeda hakimi, nur zuliani ramli and zakiah jubri.  (2020).  tocotrienol-rich fraction modulates cardiac metabolic profile changes in isoprenaline-induced myocardial infarction rats.  - sains malaysiana.  357-373. 

     

    nur hani suhaimi, japar sidik fadhlullah zuhair, mohd arlamsyah azlan, abd hamid juliana, mohd noor mohd mustazil, satirah zainalabidin, kamsiah jaarin, suhaila mohamed, yusof kamisah.  (2020).  addition of citrus leaf extract into frying oil prevents hypertension and improves vascular reactivity in heated oil-fed rats.  - journal of food and nutrition research.  417-423. 

     

    nur liyana mohammed yusof, tengku nurul tasnim tengku affendi, fatin farhana jubaidi, satirah zainalabidin, siti balkis budin.  (2020).  hibiscus sabdariffa linn. (roselle) polyphenols-rich extract prevents hyperglycemia-induced cardiac oxidative stress and mitochondrial damage in diabetic rats.  - sains malaysiana.  2499-2506. 

     

    fatin farhana jubaidi, satirah zainalabidin, vanitha mariappan, siti balkis budin.  (2020).  mitochondrial dysfunction in diabetic cardiomyopathy: the possible therapeutic roles of phenolic acids.  - international journal of molecular sciences.  1-24. 

     

    satirah zainalabidin, anand ramalingam, siti fatimah azaharah mohamed, shafreena shaukat ali, jalifah latip, wei boon yap.  (2020).  s-allylcysteine therapy reduces adverse cardiac remodelling after myocardial infarction in a rat model.  - journal of functional food.  1-7. 

     

    chee hooi chung, beatrice bretherton, satirah zainalabidin, susan a deuchars, jim deuchars, mohd kaisan mahadi.  (2020).  mediation of cardiac macrophage activity via auricular vagal nerve stimulation ameliorates cardiac ischemia/reperfusion injury.  - frontiers in neuroscience.  1-12. 

     

    satirah zainalabidin, anand ramalingam, siti fatimah azaharah mohamed, shafreena shaukat ali, jalifah latip, wei boon yap.  (2020).  s-allylcysteine therapy reduces adverse cardiac remodelling after myocardial infarction in a rat model.  - journal of functional food.  1-7. 

     

    fatin farhana jubaidi, satirah zainalabidin, vanitha mariappan, siti balkis budin.  (2020).  mitochondrial dysfunction in diabetic cardiomyopathy: the possible therapeutic roles of phenolic acids.  - international journal of molecular sciences.  1-24. 

     

    shafreena shaukat ali, siti fatimah azaharah mohamed, nur hafiqah rozalei, wei boon yap, satirah zainalabidin.  (2019).  anti-fibrotic actions of roselle extract in rat model of myocardial infarction.  - cardiovascular toxicology. 

     

    nurellya faqhiraah aziz, lislivia si yiang nee, siti balkis budin, satirah zainalabidin.  (2019).  establishment of high-fat diet induced obesity with myocardial infarction rat model.  - international journal of cardiology.  29. 

     

    khairul anwar zarkasi, satirah zainal abidin, tan jen kit, nur haleeda hakimi, nur zuliani ramli and zakiah jubri.  (2020).  tocotrienol-rich fraction modulates cardiac metabolic profile changes in isoprenaline-induced myocardial infarction rats.  - sains malaysiana.  357-373. 

     

    shafreena shaukat ali, wan amir nizam wan ahmad, siti balkis budin, satirah zainalabidin.  (2020).  implication of dietary phenolic acids on inflammation in cardiovascular disease.  - reviews in cardiovascular medicine.  225-240. 

     

    anand ramalingam, satirah zainalabidin, yusof kamisah, muhammad haffiz jauri, nurhanan murni yunos.  (2020).  cardiac glycoside 17betah neriifolin isolated from cerbera odollam enhances left ventricular contractility in normal and failing hearts ex vivo.  - journal of evolutionary biochemistry and physiology.  277-281. 

     

    nur liyana mohammed yusof, tengku nurul tasnim tengku affendi, fatin farhana jubaidi, satirah zainalabidin, siti balkis budin.  (2020).  hibiscus sabdariffa linn. (roselle) polyphenols-rich extract prevents hyperglycemia-induced cardiac oxidative stress and mitochondrial damage in diabetic rats.  - sains malaysiana.  2499-2506. 

     

    siti balkis budin, nor anita sharifuddin, fatin farhana jubaidi, satirah zainalabidin.  (2019).  the potential of hibiscus sabdariffa linn. (roselle) polyphenol-rich extract as a cardioprotective agent in myocardial infarction model.  - jurnal teknologi.  25-31. 

     

    satirah binti zainalabidin;jalifah binti latip;kamisah binti yusof.  (2020).  the cardioprotective effect of roselle against apoptosis in rat model of myocardial infarction..  - -. 

     

    kamisah binti yusof;kamsiah bt. jaarin;juriyati binti jalil;qodriyah binti haji mohd saad;satirah binti zainalabidin.  (2020).  effects of parkia speciosa ethanolic standardized extract on angiotensin ii-induced cardiomyocyte hypertrophy.  -

     

    satirah zainalabidin, si lislivia yiang-nee, norsyahida mohd fauzi and siti balkis budin.  (2019).  impact of diet-induced obesity on myocardial infarction in a rat model.  - 33rd malaysian society of pharmacology and physiology.  P07C. 

     

    satirah binti zainalabidin;siti balkis bt. budin;norsyahida binti mohd fauzi.  (2018).  the role of natural thiol donor, s-allylcysteine (sac) in protecting against myocardial ischemia-reperfusion injury.  -

     

    siti balkis bt. budin;jamaludin bin mohamed;juriyati binti jalil;satirah binti zainalabidin;norsyahida binti mohd fauzi.  (2018).  mechanism underlying cardioprotection of hibiscus sabdariffa polyphenols in diabetic rat model: modulation on mitochondria function and cardiomyocyte apoptosis.  -

     
    Projek / Project Tempoh / Period Peranan / Role
    the effects of 17ßh-neriifolin calcium regulation and oxidative stress in isoprenaline-induced heart failure model in rats 04-09-202003-09-2022 Penyelidik Bersama
    nilai terapeutik hasilan semulajadi 17-08-202016-02-2021 Penyelidik Bersama
    investigating the effects of 5-ht3 antagonists and gingerol-rich zingiber officinale extract on chronic nicotine addiction & toxicity in rodents 01-08-202031-07-2022 Penyelidik Bersama
    elucidating the role of terpenophenolic derivatives on cardiac fibrosis pathway in anthracycline-induced cardiotoxicity model 01-08-202031-07-2022 Penyelidik Bersama
    (Tiada Rekod / No Record) 02-07-202001-07-2022 Ketua Projek
    effects of selected phytochemicals from parkia speciosa pods on angiotensin ii-induced hypertrophied cardiomyocytes in vitro 01-09-201930-11-2022 Penyelidik Bersama
    role of roselle polyphenols-rich extract in modulation of cardiac function and structural changes in diabetic cardiomyopathy via pkc-mapk signaling pathways 01-09-201930-11-2022 Penyelidik Bersama
    (Tiada Rekod / No Record) 18-07-201916-07-2021 Ketua Projek
    vagus nerve stimulation: investigation on cholinergic anti-inflammatory activity and macrophage polarization in rats with induced myocardial infarction. 10-01-201910-01-2021 Penyelidik Bersama
    transcutaneous vagus nerve stimulation: investigation on macrophage polarisation through cholinergic anti-inflammatory pathway in rats with induced myocardial infarction. 15-08-201814-11-2020 Penyelidik Bersama
    the evaluation of cardiotonic effects of 17-bh-neriifolin (sna209) on angiotensin ii-induced heart failure in rats and cardiomyocyte cell line 28-03-201827-03-2020 Penyelidik Bersama
    mechanism underlying protection of roselle polyphenols in type 1 diabetic rats: modulation on cardiomyocyte hypertrophy and cell death 16-10-201715-07-2020 Penyelidik Bersama
    the cardioprotective effect of roselle against apoptosis in rat model of myocardial infarction. 16-10-201715-07-2020 Ketua Projek
    development and mechanism of action of np-ha2-m2e influenza universal vaccine in promoting humoral and cell-mediated immunity. 15-08-201714-11-2020 Penyelidik Bersama
    effects of parkia speciosa ethanolic standardized extract on angiotensin ii-induced cardiomyocyte hypertrophy 01-01-201730-06-2019 Penyelidik Bersama
    anti-fibrotic activity of roselle in rat hearts post-myocardial infarction 01-01-201731-12-2017 Ketua Projek
    toxicity test of afdhal on rats 28-10-201527-10-2016 Penyelidik Bersama
    add-x : a novel frying oil additive for global market : evaluation of the add-x product for health benefits on cardiovascular risk factors induced by heated vegetable oils 25-10-201524-10-2018 Penyelidik Bersama
    selection of labisia pumila accessions basedon the trait of high uterus contraction activity 01-08-201501-02-2017 Ketua Projek
    penerbitan kumpulan penyelidikan 15-06-201530-09-2016 Penyelidik Bersama
    lonjakan penerbitan 2015 15-06-201530-09-2016 Penyelidik Bersama
    kajian kesan suplimentasi fraksi kaya tokotrienol (trf) terhadap perubahan ekspresi protein jantung tikus teraruh iskemia-reperfusi sewaktu pelaziman iskemia 12-06-201511-06-2017 Penyelidik Bersama
    effects of add-x addition into frying oil on heated oil-induced hypertension in rats 09-04-201531-12-2017 Penyelidik Bersama
    the potential of roselle polyphenols against post-myocardial injury in obese rat 01-01-201530-09-2017 Ketua Projek
    mechanism underlying cardioprotection of hibiscus sabdariffa polyphenols in diabetic rat model: modulation on mitochondria function and cardiomyocyte apoptosis 01-12-201431-05-2018 Penyelidik Bersama
    the role of natural thiol donor, s-allylcysteine (sac) in protecting against myocardial ischemia-reperfusion injury 01-12-201431-05-2018 Ketua Projek
    malaysia laboratories for academia-business collaboration (mylab) : "add-x: a novel frying oil additive for global market":evaluation of the add-x product for health benefits on cardiovascular risk factors induced by heated vegetable oils. 13-11-201412-11-2017 Penyelidik Bersama
    signalling molecule in ischemic-reperfusion pre and post-conditioning in culture and animal study. 01-11-201431-10-2017 Penyelidik Bersama
    potential role of phenolic-rich fraction of parkia speciosa as anti-inflammatory and antioxidant agents in reducing cardiovascular risk: an in vitro study 01-08-201431-01-2017 Penyelidik Bersama
    enhancing the quality of research projects and output from the effect of add-x a noble frying additive on heated oil induced hypertension in experimental rats 01-04-201431-03-2015 Penyelidik Bersama
    regulation of nicotine-indiced mocardial injury and contractile dysfunction: role of mitochondria and sarcoplasmic reticulum 01-10-201330-09-2015 Ketua Projek
    bantuan kewangan bahan penyelidikan: satirah binti zainalabidin 01-03-201328-02-2014 Penyelia
    enhancing the quality of research projects and output from the effects of parkia speciosa (petai papan) on cardiovascular parameters in l-name-induced hypertensive rats 01-01-201331-03-2014 Penyelidik Bersama
    the effect of garcinia atroviridis on rat`s cardiovascular system 19-12-201118-06-2014 Ketua Projek
    the emerging role of adventitia in the progression of artherosclerosis in diabetic rat models 08-08-201108-08-2013 Ketua Projek