prof. madya dr. syarul nataqain binti baharum

pensyarah universiti

institut biologi sistem (inbiosis)

No. sambungan :  0389214547

No. rasmi:
UKM : 03 8921 5555



   Biografi/ Biography :
  • Upon joining INBIOSIS in 2008, she has developed and received her intensive training in the field of metabolomics at The University of Sheffield, United Kingdom under supervision of Prof. Dr. Michael Burrell and Prof. Dr. William Paul Quick. As a pioneer in Metabolomics field in Malaysia, her research is focused on the new insight of analytical and biological perspectives of the metabolomics in the field of systems biology, in particularly on the understanding of secondary metabolite production in local herbs plant as well as fluxomics studies of Lactococcus lactis. In metabolomics research, pipeline of analytical tools and multivariate analysis using PCA is essential for the dynamic high throughput analysis. This frontier analysis which includes mathematical modelling has provided glimpse of cellular biology and fingerprint of functional network in the model organism in her lab. She has published over 70 peer-reviewed indexed articles in international journals and more than 40 local and international conference proceedings in aquaculture, microbiology and metabolomics. Her work has been awarded prestigious awards including BioInnovation Awards, 2011 and Selangor My Innovation Award, 2014. She also was awarded as Visiting Lecturer to Chulalongkorn University, Thailand in 2017. She played a leading role as Malaysia representative in Asia-Oceania Metabolomics Forum (AOMF). She also engaged in collaborative partnership with industry such as FGV Sdn. Bhd., AAR Sdn. Bhd., Leave a Nest Malaysia Sdn. Bhd. and Orchid Life Sdn. Bhd. to take further steps to commercialization.

  • ng chyan leong;syarul nataqain binti baharum;goh hoe han;wan mohd aizat bin wan kamaruddin.  (2020).  systems biology approach for elucidating secondary metabolite biosynthetic pathways in mitragynine speciosa.  -

     

    low chen fei;syarul nataqain binti baharum.  (2020).  development and characterization of vibrio vulnificus-specific dna aptamer for disease diagnosis and detection in aquaculture.  -

     

    syarul nataqain binti baharum;rafidah binti ahmad;kamalrul azlan bin azizan.  (2020).  metabolite profiling of mycoparasitic fungus.  -

     

    matthew minggu, m., baharum, s. n., nor azlan, n. m., ramzi, a. b.  (2020).  development of engineered escherichia coli as whole-cell biocatalysts for surface display of pet plastic-degrading enzyme.  - asian regional conference on systems biology 2020 (arcsb2020).  42. 

     

    mazlan, o., aizat, w.m., baharum, s.n., azizan, k.a., normah, m.n..  (2020).  mangosteen seed gets in shape: metabolic to earmark seed development and germination.  - asian regional conference on systems biology 2020 (arcsb2020).  39. 

     

    zamani, a.i., barig, s., ibrahim, s., mohd. yusof, h., ibrahim, j. low, j.y.s., kua, s.f., baharum, s.n., stahmann, k-p., ng, c.l..  (2020).  comparative metabolomics of phialemonium curvatum as an omnipotent fungus cultivated on crude palm oil versus glucose.  - microbial cell factories.  1-16. 

     

    maathavi kannan, zamri zainal, ismanizan ismail, syarul nataqain baharum, hamidun bunawan.  (2020).  application of reverse genetics in functional genomics of potyvirus.  - viruses.  1-24. 

     

    siti noor fatimah binti ismail, syarul nataqain baharum, hui-yee chee, chen-fei low.  (2020).  codon deoptimization of the viral capsid protein-encoding gene attenuates macrobrachium rosenbergii nodavirus.  - aquaculture.  1-7. 

     

    a. r. sau, n. m. f. nazmie, m. s. m. yusop, m. a. akbar, m. f. m saad, s. n. baharum, n. talip, h. h. goh, h. kassim, h. bunawan.  (2020).  first report of pepper vein yellows virus and pepper yellow leaf curl virus infecting chilli pepper (capsicum annuum) in malaysia.  - plant disease.  2037. 

     

    siti farah mamat, kamalrul azlan azizan, syarul nataqain baharum, normah mohd noor, wan mohd aizat.  (2020).  gc-ms and lc-ms analyses reveal the distribution of primary and secondary metabolites in mangosteen (garcinia mangostana linn.) fruit during ripening.  - scientia horticulturae.  1-11. 

     

    mohd faiz mat saad, hoe han goh, roslee rajikan, tengku roslina tuan yusof, syarul nataqain baharum, hamidun bunawan.  (2020).  uncaria gambir (w. hunter) roxb: from phytochemical composition to pharmacological importance.  - tropical journal of pharmaceutical research.  1767-1773. 

     

    nurul raudzah adib ridzuan, teoh seong lin, norhashima abdul rashid, syarul nataqain baharum, faizah othman, farida hussan.  (2019).  protective effect of flavonoid-rich-fractions of polygonum minus against cisplatin-induced dna damage and apoptosis in rat liver.  - medicine & health.  132. 

     

    mohd shakir mohamad yusop, mohd faiz mat saad, noraini talip, syarul nataqain baharum, hamidun bunawan.  (2019).  a review on viruses infecting taro (colocasia esculenta (l.) schott).  - pathogens.  1-13. 

     

    fatin lyana azman shah, ahmad bazli ramzi, syarul nataqain baharum, normah mohd noor, hoe-han goh, thean chor leow, siti nurbaya oslan, suriana sabri.  (2019).  recent advancement of engineering microbial hosts for the biotechnological production of flavonoids.  - molecular biology reports.  6647-6659. 

     

    nr. adib ridzuan, sl. teoh, n. abdul rashid, f. othman, sn. baharum, f. hussan.  (2019).  polygonum minus ethanolic extracts attenuate cisplatin-induced oxidative stress in the cerebral cortex of rats via its antioxidant properties.  - asian pacific journal of tropical biomedicine.  196-203. 

     

    nurkhalida mohammad khalil, syarul nataqain baharum, mohd shazrul fazry sa`ariwijaya, nik marzuki sidik, fareed sairi.  (2019).  antioxidant activity of apple snail crude extracts.  - the 2018 ukm fst postgraduate colloquium, aip conference proceedings.  1-5. 

     

    nurkhalida mohammad khalil, syarul nataqain baharum, mohd shazrul fazry sa`ariwijaya, nik marzuki sidik, fareed sairi.  (2019).  antioxidant activity of apple snail crude extracts.  - the 2018 ukm fst postgraduate colloquium, aip conference proceedings.  1-5. 

     

    syarul nataqain baharum & nurdalila a`wani abd. aziz.  (2011).  status of epinephelus fuscoguttatus and epinephelus hexagonatus inferred from mitochondrial dna sequence (cytochrome b): evidence for genetic similarity.  - 2011 international conference on bioscience, biochemistry and bioinformatics (icbbb 2011), singapore. 

     

    awani aziz nurdalila, liyana amalina adnan, syarul nataqain baharum.  (2019).  innovation for sustainability and green technology degradation of inanimate forms.  - 20. 

     

    siti farah mamat, syarul nataqain baharum, kamalrul azlan azizan, normah mohd noor, wan mohd aizat wan kamaruddin.  (2019).  buah manggis proses pemasakan dan taburan sebatian kompleks.  - 163. 

     

    aqil fitri rosli, syarul nataqain baharum, goh hoe han.  (2019).  merungkai kandungan fitokimia dalam kendi periuk kera (nepenthes sp.).  - 79. 

     

    syarul nataqain baharum, kamalrul azlan azizan.  (2018).  omics applications for systems biology - advances in experimental medicine and biology 1102.  - 17. 

     

    wan mohd aizat, hoe han goh, syarul nataqain baharum.  (2018).  omics applications for systems biology.  - advances in experimental medicine and biology 1102.  99. 

     

    awani aziz nurdalila, liyana amalina adnan, syarul nataqain baharum.  (2019).  innovation for sustainability and green technology degradation of inanimate forms.  - 20. 

     

    rafidah ahmad, emelda rosleena rohani, norashikin illias, ahmad nazmi rosli, normah mohd noor, noraziah mohamd zin, syarul nataqain baharum.  (2018).  agen perencat semula jadi mikroorganisma.  - 14. 

     

    syarul nataqain baharum, kamalrul azlan azizan.  (2018).  omics applications for systems biology - advances in experimental medicine and biology 1102.  - 17. 

     

    hamidun bunawan & syarul nataqain baharum.  (2016).  essentials of single-cell analysis : concepts, applications and future prospects.  - 21. 

     

    syarul nataqain baharum, raja noor zaliha raja abd rahman, mohamad ropaning sulong, nor hafizah ahmad kamarudin, mahiran basri & abu bakar salleh.  (2013).  molecular and structural biology of new lipases and proteases.  - 2, 31-50. 

     

    siti farah mamat, syarul nataqain baharum, kamalrul azlan azizan, normah mohd noor, wan mohd aizat wan kamaruddin.  (2019).  buah manggis proses pemasakan dan taburan sebatian kompleks.  - 163. 

     

    aqil fitri rosli, syarul nataqain baharum, goh hoe han.  (2019).  merungkai kandungan fitokimia dalam kendi periuk kera (nepenthes sp.).  - 79. 

     

    wan mohd aizat, hoe han goh, syarul nataqain baharum.  (2018).  omics applications for systems biology.  - advances in experimental medicine and biology 1102.  99. 

     

    nur afiqah sukiran, goh hoe han, syarul nataqain baharum.  (2018).  kesan altitud dan suhu terhadap penghasilan sebatian kimia dalam polygonum minus.  - 108. 

     

    ismail, s. n. f., chee, h. y., baharum, s. n., and low, c. f..  (2020).  a synthetic biology approach to synthesize attenuated macrobrachium rosenbergii nodavirus using reverse genetics tool.  - asian regional conference on systems biology 2020.  48. 

     

    mazlan, o., aizat, w.m., baharum, s.n., azizan, k.a., normah, m.n..  (2020).  mangosteen seed gets in shape: metabolic to earmark seed development and germination.  - asian regional conference on systems biology 2020 (arcsb2020).  39. 

     

    matthew minggu, m., baharum, s. n., nor azlan, n. m., ramzi, a. b.  (2020).  development of engineered escherichia coli as whole-cell biocatalysts for surface display of pet plastic-degrading enzyme.  - asian regional conference on systems biology 2020 (arcsb2020).  42. 

     

    natnan, m. e., low, c. f., chong, c. m., baharum, s. n..  (2020).  gcms-based metabolomics and effect of fatty acids dietary supplementation on growth and innate immunity response of epinephelus fuscoguttatus x epinephelus lanceolatus.  - asian regional conference on systems biology 2020 (arcsb2020).  80. 

     

    ku bahaudin, a. k. n., ramzi, a. b., goh, h. h., leow, c. t., , baharum, s. n..  (2020).  omics-guided engineering of saccharomyces cerevisiae for coumarate production with polygonum minus genes.  - asian regional conference on systems biology 2020 (arcsb2020).  90. 

     
    Projek / Project Tempoh / Period Peranan / Role
    in vitro anticholinesterase effect of polygonum minus huds ethanolic extract on sh-sy5y human neuroblastoma cells. 01-10-202030-09-2022 Penyelidik Bersama
    (Tiada Rekod / No Record) 13-08-202012-08-2022 Ketua Projek
    (Tiada Rekod / No Record) 04-05-202031-12-2020 Ketua Kumpulan
    (Tiada Rekod / No Record) 13-01-202012-01-2022 Ketua Projek
    (Tiada Rekod / No Record) 20-12-2019 Penyelia
    synthetic antibody as prophylactic approach against early mortality syndrome in shrimp 01-12-201930-11-2021 Penyelidik Bersama
    microbial engineering for bio-based production of furan platform chemical 01-10-201930-09-2021 Penyelidik Bersama
    anti-virus properties of synthetic antibody against nodavirus infection in giant freshwater prawn, macrobrachium rosenbergii 01-01-201931-03-2021 Penyelidik Bersama
    high-throughput proteome dynamics for discovery of key proteins throughout the molting cycle of giant freshwater prawn 14-12-201813-03-2021 Penyelidik Bersama
    attenuation of synthetic nodavirus through codon deoptimization of virus functional genome as a tool for novel vaccine strategy in giant freshwater prawn, macrobrachium rosenbergii 15-11-201814-02-2021 Penyelidik Bersama
    anti acetylcholinesterase and anti amyloidogenic potential of polygonum minus for the treatment of alzheimer disease 01-10-201830-09-2020 Ketua Projek
    tajuk program: identifying degenerative diseases burden among elderly population in klang valley and innovative intervention modalities tajuk projek: effects of zingiber officinale active compounds on muscle ageing 01-09-201831-08-2020 Penyelidik Bersama
    development of microbial catalyst for bioconversion of methane to methanol 01-06-201831-08-2020 Penyelidik Bersama
    integrated databases in plant systems biology for societal well being 10-01-201809-01-2020 Penyelidik Bersama
    potential role of omega 9 (ω-9) as metabolic modulator to enhance innate immunity of e. fuscoguttatus against vibriosis towards aquaculture drug development 16-10-201715-10-2020 Ketua Projek
    development and characterization of vibrio vulnificus-specific dna aptamer for disease diagnosis and detection in aquaculture 16-10-201715-07-2020 Penyelidik Bersama
    the microbial biodiscovery of secondary metabolites as potential bioactive compound against pests and diseases 01-04-201730-09-2019 Ketua Projek
    the development of potential biocontrol agent for ganoderma disease in oil palm by elucidating plant-pathogen interaction biosynthetic pathways 19-12-201618-06-2018 Penyelidik Bersama
    (Tiada Rekod / No Record) 01-12-201630-11-2018 Ketua Projek
    systems biology approach for elucidating secondary metabolite biosynthetic pathways in mitragynine speciosa 24-10-201623-10-2019 Penyelidik Bersama
    isolation and characterization of compounds with anti-malarial activity from endophytic streptomyces using a metabolomic approach 01-08-201631-01-2019 Penyelidik Bersama
    pathway-based biomarker search by high-throughput metabolomics and proteomics profiling of epinephelus fuscoguttatus spleen tolerance to vibriosis 01-01-201630-06-2018 Ketua Projek
    detection and quantification of targeted oil palm metabolomics and quantification of nitrogen fixing activity in oil palm tissue culture 01-11-201531-10-2022 Ketua Projek
    metabolite profiling of mycoparasitic fungus 01-11-201530-04-2020 Ketua Projek
    metabolic engineering flavonoid production in yeast 01-09-201528-02-2018 Ketua Projek
    pemerkasaan penyelidikan berkaitan produk daripada tumbuhan dan mikroorganisma sebagai dadah baru 15-06-201530-09-2016 Penyelidik Bersama
    penghasilan penerbitan berimpak tinggi di inbiosis 15-06-201530-09-2016 Penyelidik Bersama
    biologi sistem tumbuhan dan mikrob 15-06-201530-09-2016 Penyelidik Bersama
    reconstruction of metabolic pathways in mangosteen (garcinia mangostana l.) fruit using metabolomics approach 01-03-201528-02-2018 Penyelidik Bersama
    transcriptome profiling of epinephelus fuscogutattus (tiger grouper) in response to vibrosis infection 01-01-201530-06-2017 Ketua Projek
    effect of polygonum minus leaf (daun kesum) extract on cisplatin-induced liver injury in male sprague dawley rats 01-12-201430-11-2017 Penyelidik Bersama
    proteomic and metabolomic screening of different nepenthes species 01-08-201431-07-2017 Penyelidik Bersama
    accessing the efficacy of open innovation for synthetic biology inventions 01-07-201430-06-2016 Penyelidik Bersama
    insentif penyelidikan: syarul nataqain binti baharum 01-06-201431-05-2016 Ketua Projek
    pengukuhan penerbitan dan program penyelidikan inbiosis 01-04-201431-03-2015 Penyelidik Bersama
    biologi sistem tumbuhan dan mikrob 01-04-201431-03-2015 Penyelidik Bersama
    selective microbial cultivation in palm oil to produce small bifunctional molecules as precursors for organic chemistry 01-03-201430-06-2017 Penyelidik Bersama
    uncovering the causative mechanism of low temperature sensitivity of shoot tips of a recalcitrant species – mangosteen (garcinia mangostana l.) 16-12-201331-05-2017 Penyelidik Bersama
    systemic characterisation and manipulation of phenylpropanoid pathway using microbial systems for the production of fine chemicals from lignin 01-11-201331-10-2015 Penyelidik Bersama
    exploration of polygonum minus fragrance using hyphenated gc-ms-electronic-nose (e-nose) technology for novel ccent gene(s) 01-10-201330-09-2015 Ketua Projek
    uncovering the causative mechanism of low temperature sensitivity of recalcitrant species - mangosteen (garcinia mangostana l.) 01-10-201331-12-2014 Penyelidik Bersama
    uncovering the causative mechanism of low temperature sensitivity of recalcitrant species - mangosteen (garcinia mangostana l.) 01-10-201330-09-2014 Penyelidik Bersama
    production of mangosteen suspension culture for scale-up propagation 01-09-201329-02-2016 Penyelidik Bersama
    exploration of polygonum minus fragrance using hyphenated gc-mc-electronic-nose (e-nose) technology novel scent gene(s) 01-08-201331-07-2015 Ketua Projek
    mapping of metabolites within mangosteen seed using i-maldi-ms to elucidate seed recalcitrance 01-08-201330-04-2015 Penyelidik Bersama
    increasing flavonoid production in lactococcus lactis through metabolic flux analysis 01-06-201331-03-2016 Ketua Projek
    elucidating the functional role of expansins using fourier-transform infrared (ftir) microspectroscopy 01-04-201331-03-2016 Penyelidik Bersama
    metabolite fingerprinting of epinephelus fuscoguttatus infected with vibriosis for biomarker discovery 01-04-201331-03-2016 Ketua Projek
    bantuan kewangan bahan penyelidikan: syarul nataqain binti baharum 01-03-201328-02-2014 Penyelia
    pengukuhan penerbitan dan jaringan penyelidikan inbiosis 01-01-201331-03-2014 Penyelidik Bersama
    kajian kefungsian genomik rumpai laut dan pembangunan akuakultur 01-01-201331-03-2014 Penyelidik Bersama
    biologi sistem tumbuhan dan mikrob 01-01-201331-03-2014 Penyelidik Bersama
    integrated approach to improve local papaya varieties through anther and endosperm culture 01-10-201230-03-2016 Penyelidik Bersama
    deciphering the genome of mangosteen through next-generation high-throughput sequencing and de novo sequence assembly 01-08-201231-07-2015 Penyelidik Bersama
    a novel metabolomic approach to understand recalcitrant seed development and improve agriculture industry 01-06-201229-02-2016 Penyelidik Bersama
    elucidating the gaharu resin and other biosynthetic pathways using large-scale transcriptome and metabolite profiling via comparison of infected and uninfected trees 01-12-201131-08-2015 Penyelidik Bersama
    fluxomics: understanding the metabolic network and pathway biosynthesis in lactococcus lactis 08-08-201107-08-2012 Ketua Projek
    mapping of metabolites within mangosteen seed using i-maldi-ms to reveal development patterns 08-08-201107-08-2012 Penyelidik Bersama
    mathematical model of enzyme kinetics involved in selected secondary metabolite production 01-08-201131-07-2013 Penyelidik Bersama
    improving rice traits related to biotics and stress using agriculture biotechnology 30-06-201130-09-2015 Penyelidik Bersama
    bioactive compounds from polygonum minus secondary metabolite for neutraceutical value 15-03-201014-03-2012 Ketua Projek
    metabolite fingerprinting for plant biomarker development 01-11-200931-10-2011 Ketua Projek
    unraveling plant metabolic network towards deciphering genetic blueprint 01-07-200930-06-2012 Penyelidik Bersama
    mass fry production technology of epinephelus sr (grouper) 01-05-200831-12-2011 Ketua Projek
    novel systems biology approach towards elucidation of biosynthesis networks of secondary metabolites 09-01-200731-12-2010 Penyelidik Bersama