prof. dr. syarul nataqain binti baharum

pensyarah universiti

institut biologi sistem (inbiosis)

 nataqain@ukm.edu.my



   Kluster Kepakaran/ Cluster of Expertise :
  • Sumber Lestari, Alam Sekitar dan Kehidupan Pintar,



  •    Biografi/ Biography :

  • As a pioneer in Metabolomics field in Malaysia, her research is focused on the new insight of analytical and biological perspectives of the metabolomics in the field of systems biology, in particularly on the understanding of secondary metabolite production in local herbs plant as well as fluxomics studies of Lactococcus lactis. In metabolomics research, pipeline of analytical tools and multivariate analysis using PCA is essential for the dynamic high throughput analysis. This frontier analysis which includes mathematical modelling has provided glimpse of cellular biology and fingerprint of functional network in the model organism in her lab. She has published over 120 peer-reviewed indexed articles in international journals and more than 40 local and international conference proceedings in aquaculture, microbiology and metabolomics. Her work has been awarded prestigious awards including BioInnovation Awards, 2011 and Selangor My Innovation Award, 2014. She also was awarded as Visiting Lecturer to Chulalongkorn University, Thailand in 2017. She played a leading role as Malaysia representative in Asia-Oceania Metabolomics Forum (AOMF). She also engaged in collaborative partnership with industry such as FGV Sdn. Bhd., AAR Sdn. Bhd., Leave a Nest Malaysia Sdn. Bhd. and Orchid Life Sdn. Bhd. to take further steps to commercialization.

  • syarul nataqain baharum, maya erna natnan and low chen fei.  (2025).  fatty acid as metabolic modulator to enhance innate immunity of epinephelusfuscoguttatus x epinephelus lanceolatus against vibriosis.  - the 4th international conference on agriculture, animal sciences and food technology (icaft) 2025. 

     

    syarul nataqain baharum, pei-lou wong, shubatra nahenthara raj, nurkhalida kamal, habsah aziz, ahmed mediani.  (2025).  metabolomics and molecular networking approach for exploring the therapeutics potential of medicinal plants..  - korea metabolomics society conference 2025 annual symposium and general meeting. 

     

    boshra mohd drus, low chen fei and syarul nataqain baharum.  (2025).  fluxomic analysis of vibrio resistance hybrid grouper treated with oleic acid as immune stimulant.  - asian regional conference on systems biology (arcsb2025) x international conference on natural products (icnp2025). 

     

    siti norliyana zubaidi, pei lou wong, wasim s.m. qadi, esraa adnan dawoud dawoud, hamizah shahirah hamezah, syarul nataqain baharum, faidruz azura jam, faridah abas, andres moreno, ahmed mediani.  (2025).  deciphering the mechanism of annona muricata leaf extract in alloxan-nicotinamide-induced diabetic rat model with 1h-nmr-based metabolomics approach.  - journal of pharmaceutical and biomedical analysis.  1 - 15. 

     

    syarul nataqain baharum, nur iwani akiko nasuha ahmad daud, maya erna natnan and low chen fei.  (2025).  oleic acid-enriched diet modulates metabolic pathways and enhances immune response in hybrid grouper (epinephelus fuscoguttatus × epinephelus lanceolatus) infected with vibriosis.  - asian regional conference on systems biology (arcsb2025) x international conference on natural products (icnp2025). 

     

    siti norliyana zubaidi, pei lou wong, wasim s.m. qadi, esraa adnan dawoud dawoud, hamizah shahirah hamezah, syarul nataqain baharum, faidruz azura jam, faridah abas, andres moreno, ahmed mediani.  (2025).  deciphering the mechanism of annona muricata leaf extract in alloxan-nicotinamide-induced diabetic rat model with 1h-nmr-based metabolomics approach.  - journal of pharmaceutical and biomedical analysis.  1 - 15. 

     

    norazli ghadin, syarul nataqain baharum, nurul hanun ahmad raston, chen-fei low.  (2025).  truncation-enhanced aptamer binding affinity and its potential as a sensor for macrobrachium rosenbergii nodavirus detection.  - journal of fish diseases.  1 - 9. 

     

    muhammad azizan samad, arief izzairy zamani, nazia abdul majid, saiful anuar karsani, syarul nataqain baharum, jamilah syafawati yaacob, mohd zuwairi saiman.  (2025).  an integrative approach using molecular and metabolomic studies reveals the connection of glutamic acid with telomerase and oxidative stress in berberine-treated colorectal cancer cell line hct 116.  - applied biochemistry and biotechnology.  3724 - 3747. 

     

    sheau ling puan, pirasannah erriah, normi mohd yahaya, mohd shukuri mohamad ali, siti aqlima ahmad, siti nurbaya oslan, syarul nataqain baharum, abu bakar salleh, suriana sabri.  (2025).  genome-guided identification and characterisation of broad-spectrum antimicrobial compounds of bacillus velezensis strain pd9 isolated from stingless bee propolis.  - probiotics and antimicrobial proteins.  5042 - 5065. 

     

    syasya binti yusoff, syarul nataqain binti baharum, mohd shahir shamsir bin omar, choumin chong, po-tsang lee, fazren azmi, chen fei low.  (2024).  immunoinformatics-guided selection of immunogenic peptides from betanodavirus induce antigen-specific antibody production in hybrid grouper, epinephelus fuscoguttatus x epinephelus lanceolatus.  - aquaculture.  1-8. 

     

    yasotha sundaraj, hasdianty abdullah, nima ghahremani nezhad, afiq adham abd rasib, roohaida othman, kenneth francis rodrigues, suriana sabri, syarul nataqain baharum.  (2024).  correction: sundaraj et al. cloning, expression and functional characterization of a novel a-humulene synthase, responsible for the formation of sesquiterpene in agarwood originating from aquilaria malaccensis. curr. issues mol. biol. 2023, 45, 8989–9002.  - current issues in molecular biology.  1 - 1. 

     

    hazim syahmi elias, syarul nataqain baharum, kamalrul azlan azizan, wan yaacob wan ahmad, sheela chandren, norazah basar.  (2023).  optimization of ultrasound-assisted extraction for antioxidant activity in relation to rhoifolin content of fortunella polyandra using response surface methodology (rsm).  - sains malaysiana.  153-164. 

     

    yasotha sundaraj , hasdianty abdullah, nima ghahremani nezhad, kenneth francis rodrigues, suriana sabri, syarul nataqain baharum.  (2023).  cloning, expression and functional characterization of a novel a humulene synthase, responsible for the formation of sesquiterpene in agarwood originating from aquilaria malaccensis.  - current issues in molecular biology.  8989-9002. 

     

    fatin lyana azman shah, syarul nataqain baharum, hoe han goh, thean chor leow, ahmad bazli ramzi, siti nurbaya oslan, suriana sabri.  (2023).  molecular cloning and in silico analysis of chalcone isomerase from polygonum minus.  - molecular biology reports.  1-12. 

     

    syarul nataqain baharum, yosmetha mayalvanan, maya erna natnan, kamalrul azlan azizan, hamidun bunawan, nik raikhan nik him, chen fei low, chou min chong.  (2022).  lc-qtof-ms analysis of fish immune organs reveals the distribution of amino acids in response to metabolic adaptation of the survival phenotype in grouper against vibrio infection.  - 3 biotech.  1-16. 

     

    siti norliyana zubaidi, pei lou wong, wasim s.m. qadi, esraa adnan dawoud dawoud, hamizah shahirah hamezah, syarul nataqain baharum, faidruz azura jam, faridah abas, andres moreno, ahmed mediani.  (2025).  deciphering the mechanism of annona muricata leaf extract in alloxan-nicotinamide-induced diabetic rat model with 1h-nmr-based metabolomics approach.  - journal of pharmaceutical and biomedical analysis.  1 - 15. 

     

    norazli ghadin, syarul nataqain baharum, nurul hanun ahmad raston, chen-fei low.  (2025).  truncation-enhanced aptamer binding affinity and its potential as a sensor for macrobrachium rosenbergii nodavirus detection.  - journal of fish diseases.  1 - 9. 

     

    darvien gunasekaran, syazwani basir, noraini talip, ahmad bazli ramzi, syarul nataqain baharum, hamidun bunawan.  (2025).  integrated transcriptomic and metabolomic profiling of breynia androgyna (l.) tissues.  - bmc research notes.  1 - 5. 

     

    muhammad azizan samad, arief izzairy zamani, nazia abdul majid, saiful anuar karsani, syarul nataqain baharum, jamilah syafawati yaacob, mohd zuwairi saiman.  (2025).  an integrative approach using molecular and metabolomic studies reveals the connection of glutamic acid with telomerase and oxidative stress in berberine-treated colorectal cancer cell line hct 116.  - applied biochemistry and biotechnology.  3724 - 3747. 

     

    rafidah ahmad, nurul fadhilah marzuki, syarul nataqain baharum, yit kheng goh, kamalrul azlan azizan, ahmad bazli ramzi, tuan nur fatihah tuan pa, cu ean ong, you keng goh, kah joo goh, tasren nazir mahamooth.  (2025).  metabolite profiling of bipartite interaction between mycoparasitic scytalidium parasiticum and pathogenic ganoderma boninense with co-culturing system reveals the roles of biocontrol agent in suppressing phytopathogen.  - archives of phytopathology and plant protection.  1038 - 1054. 

     

    nurkhalida mohammad khalil, syarul nataqain baharum, mohd shazrul fazry sa`ariwijaya, nik marzuki sidik, fareed sairi.  (2019).  antioxidant activity of apple snail crude extracts.  - the 2018 ukm fst postgraduate colloquium, aip conference proceedings.  1-5. 

     

    syarul nataqain baharum & nurdalila a`wani abd. aziz.  (2011).  status of epinephelus fuscoguttatus and epinephelus hexagonatus inferred from mitochondrial dna sequence (cytochrome b): evidence for genetic similarity.  - 2011 international conference on bioscience, biochemistry and bioinformatics (icbbb 2011), singapore. 

     

    rafidah ahmad, mohd fauzi abd razak, emelda rosseleena rohani, syarul nataqain baharum .  (2024).  rancangan pengumpulan semula (rps) air banun ( air banun resettlement programme (rps).  - 13 - 21. 

     

    ahmed mediani, syarul nataqain baharum.  (2024).  metabolomics: challenges and opportunities in systems biology studies.  - 2745.  77-102. 

     

    emelda rosseleena rohani, rafidah ahmad, mohd faiz mat saad, intan azlinda ramlee, syarul nataqain baharum.  (2024).  tumbuhan perubatan dan herba suku jahai (medical plants and herbs of the jahai tribe) .  - 48 - 51. 

     

    awani aziz nurdalila, liyana amalina adnan, syarul nataqain baharum.  (2019).  the effect of vibrio vulnificus infection on starved epinephelus fuscoguttatus analysed using gcms.  - -.  17-36. 

     

    syarul nataqain baharum, kamalrul azlan azizan.  (2018).  metabolomics in systems biology.  - advances in experimental medicine and bi.  51-68. 

     

    dr. khairul anwar ishak dan prof. dr. syarul nataqain baharum.  (2025).  inbiosis 20 tahun melangkaui zaman.  - berita ukm, portal berita universiti kebangsaan malaysia. 

     

    rubashiny veeramohan, syarul nataqain baharum, ng chyan leong.  (2024).  merungkai tapak jalan biosintesis alkaloid indol mitragyna speciosa melalui pendekatan intergrasi omik.  -

     

    emelda rosseleena rohani, rafidah ahmad, mohd faiz mat saad, intan azlinda ramlee, syarul nataqain baharum.  (2024).  tumbuhan perubatan dan herba suku jahai (medical plants and herbs of the jahai tribe) .  - 48 - 51. 

     

    rafidah ahmad, mohd fauzi abd razak, emelda rosseleena rohani, syarul nataqain baharum .  (2024).  rancangan pengumpulan semula (rps) air banun ( air banun resettlement programme (rps).  - 13 - 21. 

     

    fahmeeda mohd jazamuddin, low chen fei, syarul nataqain baharum.  (2024).  ikan kerapu harimau : pemprofilan transkriptom dan proteom ikan terhadap jangkitan penyakit vibriosis.  -

     

    syarul nataqain baharum, nur iwani akiko nasuha ahmad daud, maya erna natnan and low chen fei.  (2025).  oleic acid-enriched diet modulates metabolic pathways and enhances immune response in hybrid grouper (epinephelus fuscoguttatus × epinephelus lanceolatus) infected with vibriosis.  - asian regional conference on systems biology (arcsb2025) x international conference on natural products (icnp2025). 

     

    maya erna natnan, syarul nataqain baharum, low chen fei.  (2025).  dietary oleic acid modulates lipid profiles and enhanced immunity in vibrio- challenged hybrid grouper.  - asian regional conference on systems biology (arcsb2025) x international conference on natural products (icnp2025). 

     

    puteri elysa alia mohd badri, nor syaidatul akmal mohd yousof, nurkhalida kamal, kyo bin kang, syarul nataqain baharum and habsah aziz .  (2025).  phytochemical mapping of polygonum minus extracts by lc-ms/ms and molecular networking towards natural product discovery.  - international postgraduate colloquium in health sciences and pharmacy (inchap 2025). 

     

    puteri elysa alia mohd badri, nor syaidatul akmal mohd yousof, maizatul hasyima omar, nurkhalida kamal, rafidah ahmad, ahmed mediani, hamidun bunawan, syarul nataqain baharum and habsah aziz .  (2025).  lc-ms/ms profiling and molecular docking of polygonum minus bioactive compounds targeting key receptors in acute myeloid leukemia.  - asian regional conference on systems biology 2025 (arcsb2025) and international conference on natural products 2025 (icnp2025). 

     

    habsah aziz, puteri elysa alia mohd badri, nor syaidatul akmal mohd yousof, nurkhalida kamal, huong t. pham, kyo bin kang, ahmed mediani, hamidun bunawan, syarul nataqain baharum .  (2025).  comparative profiling of the phytochemical landscape in polygonum minus using lc-ms/ms and molecular networking.  - asian regional conference on systems biology 2025 (arcsb2025) and international conference on natural products 2025 (icnp2025). 

     

    BIOTECHNOLOGY :PURE AND APPLIED SCIENCES
    Molecular Biology
    Pengalaman / Experience : 22 tahun/years(s)

    BIOTECHNOLOGY :PURE AND APPLIED SCIENCES
    Metabolic engineering
    Pengalaman / Experience : 11 tahun/years(s)

    BIOTECHNOLOGY :PURE AND APPLIED SCIENCES
    Functional Metabolomics
    Pengalaman / Experience : 16 tahun/years(s)

    BIOTECHNOLOGY :PURE AND APPLIED SCIENCES
    Systems Biology
    Pengalaman / Experience : 16 tahun/years(s)