prof. madya dr. tan toh leong

pensyarah perubatan

jabatan perubatan kecemasan

 sebastianttl@yahoo.co.uk



   Kluster Kepakaran/ Cluster of Expertise :


  •    Biografi/ Biography :

  • Assoc Professor Dr Tan Toh Leong is a senior lecturer and Emergency Physician currently works at the Department of Emergency Medicine, National University of Malaysia. His research interest is in Sepsis, Infection, Emergency Critical Care, Translational Research, Point-of-care test, Molecular Biology, and Antibiotic stewardship. He is currently the Asia Pacific Sepsis Alliance steering comittee which aim to work with all interested parties and countries to enact the 2017 WHA resolution, WHO, to improve the outcomes of patients with sepsis in the Asia Pacific region. He is also currently the President for Malaysian Sepsis Alliance. The official website is at https://www.mysepsis.org.
    Bahasa Malaysia English Mandarin (华语)

  • evelyn chau yi wen, khaizurin tajul arifin, tan toh leong.  (2025).  when the brain short-circuits.  - newswav, health & fitness. 

     

    loo say yee, khaizurin tajul arifin, tan toh leong .  (2025).  silent wings, deadly threats- mosquito bites in malaysia.  - newswav. 

     

    chee lan lau, ramliza ramli, petrick periyasamy, toh leong tan, hui-min neoh, aliza mohamad yusof, zainina zainal abidin, noranati zulkifli chia, mohd syazwan mohd saaid, munirah abdul aziz, isa naina-mohamed.  (2025).  performance of direct-from-blood-culture disk diffusion antibiotic susceptibility testing and its impact on antibiotic adjustment in bloodstream infections at a malaysian tertiary center.  - microbiology spectrum.  1 - 19. 

     

    nor safiahani mhd yunin, toh leong tan.  (2025).  national early warning score 2 (news2) as a prognostic tool for adult patients in emergency department: a retrospective observational study.  - plos one.  1 - 16. 

     

    nurul saadah ahmad, rafidah ahmad, muhammad faizan abdul shukor, rosni ibrahim, toh leong tan, syarul nataqain baharum, zamberi sekawi.  (2025).  optimization of human serum and plasma samples extraction for enhanced lipid yield using untargeted lc-im-qtof-ms.  - asian regional conference on systems biology (arcsb2025) x international conference on natural products (icnp2025). 

     

    louise thwaites, prashant nasa, brett abbenbroek, vu quoc dat, simon finfer, arthur kwizera, lowell ling, suzana m. lobo, robert sinto, dita aditianingsih, massimo antonelli, yaseen m. arabi1, andrew argent, luciano azevedo, elizabeth bennett, arunaloke chakrabarti, kevin de asis, jan de waele, jigeeshu vasishtha divatia, elisa estenssoro, laura evans, abul faiz, naomi e. hammond, madiha hashmi, margaret s. herridge, shevin t. jacob, jimba jatsho, yash javeri, karima khalid, lie khie chen, mitchell levy, ganbold lundeg, flavia r. machado, yatin mehta, mervyn mer, do ngoc son, gustavo a. ospina-tascn, marlies ostermann, chairat permpikul, hallie c. prescott, konrad reinhart, gloria rodriguez vega, halima s-kabara, gentle sunder shrestha, wangari waweru-siika, toh leong tan, subhash todi, swagata tripathy, balasubramaniam venkatesh, jean-louis vincent and sheila nainan myatra.  (2025).  management ofadult sepsis inresource-limited settings: global expert consensus statements using a delphi method .  - intensive care medicine.  21 - 38. 

     

    johayra prithula , khandaker reajul islam , jaya kumar, toh leong tan, mamun bin ibne reaz, tawsifur rahman, susu m. zughaierf, muhammad salman khan ,m. murugappan, muhammad e.h. chowdhury.  (2025).  a novel classical machine learning framework for early sepsis prediction using electronic health record data from icu patients.  - computers in biology and medicine.  1 - 16. 

     

    nor safiahani mhd yunin, toh leong tan.  (2025).  national early warning score 2 (news2) as a prognostic tool for adult patients in emergency department: a retrospective observational study.  - plos one.  1 - 16. 

     

    chee lan lau, ramliza ramli, petrick periyasamy, toh leong tan, hui-min neoh, aliza mohamad yusof, zainina zainal abidin, noranati zulkifli chia, mohd syazwan mohd saaid, munirah abdul aziz, isa naina-mohamed.  (2025).  performance of direct-from-blood-culture disk diffusion antibiotic susceptibility testing and its impact on antibiotic adjustment in bloodstream infections at a malaysian tertiary center.  - microbiology spectrum.  1 - 19. 

     

    chee lan lau, hui-min neoh, petrick periyasamy, tg mohd ikhwan tg abu bakar sidik, toh leong tan, ramliza ramli and isa naina mohamed.  (2024).  prevalence and clinical significance of the genotypic carriage among esbl phenotype-negative escherichia coli and klebsiella pneumoniae clinical isolates in bacteremia: a study in a malaysian tertiary center.  - frontiers in cellular and infection microbiology.  1 - 15. 

     

    chuan h ding, shiamala d navarathinam, hui-min neoh, toh l tan.  (2024).  the first reported case of candidemia caused by the novel candida tropicalis diploid sequence type 1515.  - journal of infection in developing countries.  353 - 357. 

     

    shiamala devi navarathinam, hui-min neoh, toh leong tan, chuan hun ding.  (2023).  triazole resistance in candida tropicalis: are we in dire straits?.  - malaysian journal of pathology.  552. 

     

    shiamala devi navarathinam, hui-min neoh, toh leong tan, asrul abdul wahab, mohd nizam tzar, chuan hun ding.  (2023).  antifungal susceptibility profile and biofilm-producing capability of candida tropicalis isolates in a tertiary medical centre.  - malaysian journal of pathology.  417-424. 

     

    siti nur azwa md shahid, azlin itnin, raja zahratul azma raja sabudin, hafiza alauddin, toh leong tan.  (2023).  evaluation of mean neutrophil volume and immature to total neutrophil ratio as a biomarker for bacterial sepsis in adult patients.  - malaysian journal of pathology.  77-85. 

     

    faiezah kamaruzaman, tan toh leong.  (2019).  local anaesthesia systemic toxicity (last) - a stroke mimicker.  - medicine & health.  266-269. 

     

    nor safiahani mhd yunin, toh leong tan.  (2025).  national early warning score 2 (news2) as a prognostic tool for adult patients in emergency department: a retrospective observational study.  - plos one.  1 - 16. 

     

    johayra prithula , khandaker reajul islam , jaya kumar, toh leong tan, mamun bin ibne reaz, tawsifur rahman, susu m. zughaierf, muhammad salman khan ,m. murugappan, muhammad e.h. chowdhury.  (2025).  a novel classical machine learning framework for early sepsis prediction using electronic health record data from icu patients.  - computers in biology and medicine.  1 - 16. 

     

    chee lan lau, ramliza ramli, petrick periyasamy, toh leong tan, hui-min neoh, aliza mohamad yusof, zainina zainal abidin, noranati zulkifli chia, mohd syazwan mohd saaid, munirah abdul aziz, isa naina-mohamed.  (2025).  performance of direct-from-blood-culture disk diffusion antibiotic susceptibility testing and its impact on antibiotic adjustment in bloodstream infections at a malaysian tertiary center.  - microbiology spectrum.  1 - 19. 

     

    louise thwaites, prashant nasa, brett abbenbroek, vu quoc dat, simon finfer, arthur kwizera, lowell ling, suzana m. lobo, robert sinto, dita aditianingsih, massimo antonelli, yaseen m. arabi1, andrew argent, luciano azevedo, elizabeth bennett, arunaloke chakrabarti, kevin de asis, jan de waele, jigeeshu vasishtha divatia, elisa estenssoro, laura evans, abul faiz, naomi e. hammond, madiha hashmi, margaret s. herridge, shevin t. jacob, jimba jatsho, yash javeri, karima khalid, lie khie chen, mitchell levy, ganbold lundeg, flavia r. machado, yatin mehta, mervyn mer, do ngoc son, gustavo a. ospina-tascn, marlies ostermann, chairat permpikul, hallie c. prescott, konrad reinhart, gloria rodriguez vega, halima s-kabara, gentle sunder shrestha, wangari waweru-siika, toh leong tan, subhash todi, swagata tripathy, balasubramaniam venkatesh, jean-louis vincent and sheila nainan myatra.  (2025).  management ofadult sepsis inresource-limited settings: global expert consensus statements using a delphi method .  - intensive care medicine.  21 - 38. 

     

    chee lan lau, hui-min neoh, petrick periyasamy, tg mohd ikhwan tg abu bakar sidik, toh leong tan, ramliza ramli and isa naina mohamed.  (2024).  prevalence and clinical significance of the genotypic carriage among esbl phenotype-negative escherichia coli and klebsiella pneumoniae clinical isolates in bacteremia: a study in a malaysian tertiary center.  - frontiers in cellular and infection microbiology.  1 - 15. 

     

    tan toh leong.  (2021).  sepsis prevalence and burden.  - 115-123. 

     

    tan toh leong.  (2020).  dengue pathophysiology: from bench to bedside.  - 13-22. 

     

    tan toh leong, khor chin chuan.  (2019).  deranged liver function: a strong indicator for severe dengue.  - 29-36. 

     

    nurul saadah ahmad, tan toh leong, khaizurin tajul arifin.  (2021).  fungsi & kepentingan enzim fosfolipase a2 kumpulan iia rembesan (spla2-iia) dalam sepsis jangkitan bakteria.  - 95. 

     

    nurul saadah ahmad, tan toh leong.  (2020).  tatacara kerja (sop) permohonan penggunaan salinan pendua/komputer c-hets untuk tujuan pengumpulan data penyelidikan jabatan perubatan kecemasan, hctm.  - 1-3. 

     

    neoh hui-min, tan toh leong.  (2019).  ancaman bakteria mrsa.  - al-siha.  10-11. 

     

    tan toh leong, neoh hui-min.  (2019).  data raya dan sepsis, apakah kaitan antara keduanya.  - al-siha.  17. 

     

    tan xin ee, neoh hui-min, tan toh leong.  (2019).  staphylococcus aureus rintang metisilin dan vankomisin.  - 70. 

     

    loo say yee, khaizurin tajul arifin, tan toh leong .  (2025).  silent wings, deadly threats- mosquito bites in malaysia.  - newswav. 

     

    evelyn chau yi wen, khaizurin tajul arifin, tan toh leong.  (2025).  when the brain short-circuits.  - newswav, health & fitness. 

     

    evelyn chau yi wen, tan toh leong, khaizurin tajul ariffin.  (2025).  purple panic! when grannys urine turns purple.  - https://newswav.com/article/purple-panic-when-granny-s-urine-turns-purple-a2503_e3man2. 

     

    nurul saadah ahmad, rafidah ahmad, muhammad faizan abdul shukor, rosni ibrahim, toh leong tan, syarul nataqain baharum, zamberi sekawi.  (2025).  optimization of human serum and plasma samples extraction for enhanced lipid yield using untargeted lc-im-qtof-ms.  - asian regional conference on systems biology (arcsb2025) x international conference on natural products (icnp2025). 

     

    nurul huda ahmad, khaizurin tajul arifin, tan toh leong.  (2025).  always online, rarely okay: protecting your mental health in the digital age.  - newswav. 

     

    MEDICINE :CLINICAL AND HEALTH SCIENCES
    Sepsis, Infection, Inflammation, Critical Care, Emergency Resuscitation, Molecular Biology
    Pengalaman / Experience : 10 tahun/years(s)

    BIOTECHNOLOGY :PURE AND APPLIED SCIENCES
    sepsis biosensor kits
    Pengalaman / Experience : tahun/years(s)

    BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
    sepsis
    Pengalaman / Experience : tahun/years(s)