dr. ezanee azlina binti mohamad hanif

pensyarah universiti

institut biologi molekul perubatan ukm (umbi)

 ezanee.azlina.mohamad.hanif@ppukm.ukm.edu.my

No. Telefon Rasmi :  60391459069

No. rasmi:
UKM : 03 8921 5555



   Biografi/ Biography :

  • Dr. Ezanee received her first degree in University Malaya (Genetics & Molecular Biology), then carried on her passion in science by enrolling as a full-time Master student in the Faculty of Medicine, UKM. Her research then looking into chromosomal aberrations in thyroid neoplasms and was exposed in several molecular cytogenetic techniques (CGH, array-CGH) and BRCA1/ BRCA2 mutation detection in breast cancer (PCR, sequencing). Immediately after, Dr Ezanee joined as a tutor in UKM Medical Molecular Biology Institute (UMBI) (2008), then converted her post to Young research fellow (2009) upon receiving her Master degree (MMed.Sc. Pathology). In 2008-2012, she was involved in several projects such as the Genotyping XMEs in breast and cervical cancer, a genome-wide methylation analysis of breast and colorectal cancers and Diabetic GWAS, all utilising the microarray applications. She was involved in the Lab Accreditation MS ISO/IEC: 17025 as Technical Manager (2009-2011). In 2012, she pursued her Ph.D degree in Centre for Cancer Research and Cell Biology, Queen’s University Belfast, UK where she conducted research studying the underlying molecular mechanisms in driving poor prognosis in triple negative breast cancer (TNBC). In the UK, she was also the vice-president for the Malaysian Postgraduate in Northern Ireland (MyPNI) taking parts in group knowledge sharing and charity activities. She was conferred her Ph.D (Medicine) in 2017, a year after her viva voce. Upon returning, Dr Ezanee is actively applying for research grants and succeeded to obtain 3 research grants in triple negative breast cancer as principle investigator. She is also a co-researcher for 6 other projects related to her field and expertise. She is also actively involved in MS ISO/IEC 17025:2017 as Approved Signatory for HLA B*1502 genotyping in epilepsy and was part of the national emergency COVID-19 task force as Approved signatory. Dr Ezanee now has six students under her supervision both as main (2) and co-supervisor (4).

  • lishantini pearanpan,fariza juliana nordin,ee ling siew ,endang kumolosasi,ezanee azlina mohamad hanif,siti fathiah masre,eng wee chua,hong sheng cheng,nor fadilah rajab.  (2022).  a cell-based systematic review on the role of annexin a1 in triple-negative breast cancers.  - internation journal of molecular sciences.  1-16. 

     

    muhammad nur adam hatta, ezanee azlina mohamad hanif, siok-fong chin, hui-min neoh.  (2021).  pathogens and carcinogenesis: a review.  - biology.  1-22. 

     

    tan shing cheng;a. rahman bin a. jamal;norlia bt. abdullah;nazihah binti abd. jalal;noraidatulakma binti abdullah @ muda;ezanee azlina binti mohamad hanif;nurul syakima binti ab mutalib.  (2021).  functional polymorphisms in microrna genes and their influence on breast cancer susceptibility.  -

     

    nor azila ma, nor azian am, azmawati mn, sharifah azura s, petrick p, najma k, mohd rohaizat h, norfazilah a, anita s, hanita o, tuti ningseh md, nurul syakima am, ezanee azlina, siti aishah, nurul syeefa', abdul rashid, abdul halim, hanafiah hr, rahman j.  (2021).  covid-19 in malaysia: exposure assessment and prevention practices among healthcare workers at a teaching hospital.  - journal of infection in developing countries.  1816-1824. 

     

    mohd. firdaus che mat, ezanee azlina mohamad hanif, nor azian abdul murad, kamariah ibrahim, roslan harun, rahman jamal.  (2021).  silencing of zfp36l2 increases sensitivity to temozolomide through g2/m cell cycle arrest and bax mediated apoptosis in gbm cells.  - molecular biology reports.  1493-1503. 

     

    lishantini pearanpan,fariza juliana nordin,ee ling siew ,endang kumolosasi,ezanee azlina mohamad hanif,siti fathiah masre,eng wee chua,hong sheng cheng,nor fadilah rajab.  (2022).  a cell-based systematic review on the role of annexin a1 in triple-negative breast cancers.  - internation journal of molecular sciences.  1-16. 

     

    shing cheng tan, teck yew low, ezanee azlina mohamad hanif, mohamad ayub khan sharzehan, hamed kord-varkaneh & md asiful islam.  (2021).  the rs9340799 polymorphism of the estrogen receptor alpha (esr1) gene and its association with breast cancer susceptibility.  - scientific reports.  18619. 

     

    muhammad nur adam hatta, ezanee azlina mohamad hanif, siok-fong chin, hui-min neoh.  (2021).  pathogens and carcinogenesis: a review.  - biology.  1-22. 

     

    su min lim, ezanee azlina mohamad hanif, siok-fong chin.  (2021).  is targeting autophagy mechanism in cancer a good approach? the possible double-edge sword effect.  - cell and bioscience.  1-13. 

     

    su min lim, ezanee azlina mohamad hanif, siok-fong chin.  (2020).  modulation of leucine-rich-alpha-2-glycoprotein 1 (lrg1) promotes the survival of low-grade colorectal cancer via suppression of autophagy but not in high-grade cancer.  - gut.  A22. 

     

    nor azila ma, nor azian am, azmawati mn, sharifah azura s, petrick p, najma k, mohd rohaizat h, norfazilah a, anita s, hanita o, tuti ningseh md, nurul syakima am, ezanee azlina, siti aishah, nurul syeefa', abdul rashid, abdul halim, hanafiah hr, rahman j.  (2021).  covid-19 in malaysia: exposure assessment and prevention practices among healthcare workers at a teaching hospital.  - journal of infection in developing countries.  1816-1824. 

     

    mohd. firdaus che mat, ezanee azlina mohamad hanif, nor azian abdul murad, kamariah ibrahim, roslan harun, rahman jamal.  (2021).  silencing of zfp36l2 increases sensitivity to temozolomide through g2/m cell cycle arrest and bax mediated apoptosis in gbm cells.  - molecular biology reports.  1493-1503. 

     

    ezanee azlina mohamad hanif.  (2019).  dysregulation of non-histone molecule mir205 and lrg1 post-transcriptional de-regulation by setd1a in triple negative breast cancer..  - molecular biology reports.  6617-6624. 

     

    ezanee azlina mohamad hanif, shamsul azhar shah.  (2018).  overview on epigenetic re-programming: a potential therapeutic intervention in triple negative breast cancers.  - asian pacific journal of cancer prevention. 

     

    lishantini pearanpan,fariza juliana nordin,ee ling siew ,endang kumolosasi,ezanee azlina mohamad hanif,siti fathiah masre,eng wee chua,hong sheng cheng,nor fadilah rajab.  (2022).  a cell-based systematic review on the role of annexin a1 in triple-negative breast cancers.  - internation journal of molecular sciences.  1-16. 

     

    nor azila ma, nor azian am, azmawati mn, sharifah azura s, petrick p, najma k, mohd rohaizat h, norfazilah a, anita s, hanita o, tuti ningseh md, nurul syakima am, ezanee azlina, siti aishah, nurul syeefa', abdul rashid, abdul halim, hanafiah hr, rahman j.  (2021).  covid-19 in malaysia: exposure assessment and prevention practices among healthcare workers at a teaching hospital.  - journal of infection in developing countries.  1816-1824. 

     

    shing cheng tan, teck yew low, ezanee azlina mohamad hanif, mohamad ayub khan sharzehan, hamed kord-varkaneh & md asiful islam.  (2021).  the rs9340799 polymorphism of the estrogen receptor alpha (esr1) gene and its association with breast cancer susceptibility.  - scientific reports.  18619. 

     

    mohd. firdaus che mat, ezanee azlina mohamad hanif, nor azian abdul murad, kamariah ibrahim, roslan harun, rahman jamal.  (2021).  silencing of zfp36l2 increases sensitivity to temozolomide through g2/m cell cycle arrest and bax mediated apoptosis in gbm cells.  - molecular biology reports.  1493-1503. 

     

    su min lim, ezanee azlina mohamad hanif, siok-fong chin.  (2021).  is targeting autophagy mechanism in cancer a good approach? the possible double-edge sword effect.  - cell and bioscience.  1-13. 

     

    kha wai hon, norahayu othman, ezanee azlina mohamad hanif, siti nurmi nasir, nur syahada abd razak, rahman jamal, nadiah abu.  (2020).  drug resistance in colorectal cancer: molecular mechanisms and therapeutic strategies.  - 17. 

     

    ezanee azlina mohamad hanif.  (2020).  kromosom dan mekanisme gen: keupayaan diagnostik dalam pembentukan lesi/neoplasma tiroid.  - 74. 

     

    kha wai hon, norahayu othman, ezanee azlina mohamad hanif, siti nurmi nasir, nur syahada abd razak, rahman jamal, nadiah abu.  (2020).  drug resistance in colorectal cancer: molecular mechanisms and therapeutic strategies.  - 17. 

     

    siti aishah sulaiman, nor azian abdul murad, ezanee azlina mohamad hanif, nadiah abu, and rahman jamal.  (2018).  circular rna: biogenesis and function.  - 370. 

     

    ezanee azlina mohamad hanif.  (2020).  kromosom dan mekanisme gen: keupayaan diagnostik dalam pembentukan lesi/neoplasma tiroid.  - 74. 

     

    tan shing cheng;a. rahman bin a. jamal;norlia bt. abdullah;nazihah binti abd. jalal;noraidatulakma binti abdullah @ muda;ezanee azlina binti mohamad hanif;nurul syakima binti ab mutalib.  (2021).  functional polymorphisms in microrna genes and their influence on breast cancer susceptibility.  -

     

    su min lim, ezanee azlina mohamad hanif, siok-fong chin.  (2020).  modulation of leucine-rich-alpha-2-glycoprotein 1 (lrg1) promotes the survival of low-grade colorectal cancer via suppression of autophagy but irreversible in high-grade cancer.  - international digestive disease forum (iddf) 2020.  1. 

     

    lim sm, mohamad hanif ea, chin s-f.  (2020).  overexpression of lrg1 supresses autophagy mechanism possible via tgfb superfamily in colorectal cancer.  - minggu penyelidikan perubatan & kesihatan ke-22.  1. 

     

    nurul nadiah ahmad daud, siok-fong chin, nor fadilah rajab, ezanee azlina mohamad hanif.  (2020).  deciphering cryptic intra-tumoral hallmark of tgfb isoforms in triple negative breast cancer (tnbc).  - 22nd medical and health research week 2020.  1. 

     

    ezanee azlina binti mohamad hanif;a. rahman bin a. jamal;amalia afzan binti saperi.  (2020).  identification of epithelial-to-mesenchymal-transition (emt) targets of epigenetic regulator setd1a in triple negative breast cancers (tnbcs)..  -