dr. ezanee azlina binti mohamad hanif

pensyarah universiti

institut biologi molekul perubatan ukm (umbi)

 ezanee.azlina.mohamad.hanif@ppukm.ukm.edu.my

No. sambungan :  60391459069

No. rasmi:
UKM : 03 8921 5555



   Biografi/ Biography :

  • Dr. Ezanee received her first degree in University Malaya (Genetics & Molecular Biology), then carried on her passion in science by enrolling as a full-time Master student in the Faculty of Medicine, UKM. Her research then looking into chromosomal aberrations in thyroid neoplasms and was exposed in several molecular cytogenetic techniques (CGH, array-CGH) and BRCA1/ BRCA2 mutation detection in breast cancer (PCR, sequencing). Immediately after, Dr Ezanee joined as a tutor in UKM Medical Molecular Biology Institute (UMBI) (2008), then converted her post to Young research fellow (2009) upon receiving her Master degree (MMed.Sc. Pathology). In 2008-2012, she was involved in several projects such as the Genotyping XMEs in breast and cervical cancer, a genome-wide methylation analysis of breast and colorectal cancers and Diabetic GWAS, all utilising the microarray applications. She was involved in the Lab Accreditation MS ISO/IEC: 17025 as Technical Manager (2009-2011). In 2012, she pursued her Ph.D degree in Centre for Cancer Research and Cell Biology, Queen’s University Belfast, UK where she conducted research studying the underlying molecular mechanisms in driving poor prognosis in triple negative breast cancer (TNBC). In the UK, she was also the vice-president for the Malaysian Postgraduate in Northern Ireland (MyPNI) taking parts in group knowledge sharing and charity activities. She was conferred her Ph.D (Medicine) in 2017, a year after her viva voce. Upon returning, Dr Ezanee is actively applying for research grants and succeeded to obtain 3 research grants in triple negative breast cancer as principle investigator. She is also a co-researcher for 6 other projects related to her field and expertise. She is also actively involved in MS ISO/IEC 17025:2017 as Approved Signatory for HLA B*1502 genotyping in epilepsy and was part of the national emergency COVID-19 task force as Approved signatory. Dr Ezanee now has six students under her supervision both as main (2) and co-supervisor (4).

  • muhammad nur adam hatta, ezanee azlina mohamad hanif, siok-fong chin, hui-min neoh.  (2021).  pathogens and carcinogenesis: a review.  - biology.  1-22. 

     

    su min lim, ezanee azlina mohamad hanif, siok-fong chin.  (2021).  is targeting autophagy mechanism in cancer a good approach? the possible double-edge sword effect.  - cell and bioscience.  1-13. 

     

    mohd. firdaus che mat, ezanee azlina mohamad hanif, nor azian abdul murad, kamariah ibrahim, roslan harun, rahman jamal.  (2021).  silencing of zfp36l2 increases sensitivity to temozolomide through g2/m cell cycle arrest and bax mediated apoptosis in gbm cells.  - molecular biology reports.  1493-1503. 

     

    muhammad nur adam hatta, ezanee azlina mohamad hanif, siok-fong chin, hui-min neoh.  (2021).  prerequisite evaluation of anaerobic settings for gut microbiome functional studies.  - journal of biomedicine and translational research.  48-50. 

     

    su min lim, ezanee azlina mohamad hanif, siok-fong chin.  (2020).  modulation of leucine-rich-alpha-2-glycoprotein 1 (lrg1) promotes the survival of low-grade colorectal cancer via suppression of autophagy but not in high-grade cancer.  - gut.  A22. 

     

    su min lim, ezanee azlina mohamad hanif, siok-fong chin.  (2021).  is targeting autophagy mechanism in cancer a good approach? the possible double-edge sword effect.  - cell and bioscience.  1-13. 

     

    muhammad nur adam hatta, ezanee azlina mohamad hanif, siok-fong chin, hui-min neoh.  (2021).  pathogens and carcinogenesis: a review.  - biology.  1-22. 

     

    shivapriya jeyamaran, ezanee azlina mohamad hanif, nurul syakima ab mutalib, rahman jamal, nadiah abu.  (2020).  circular rnas: potential regulators of treatment resistance in human cancers.  - frontiers in genetics.  1-10. 

     

    su min lim, ezanee azlina mohamad hanif, siok-fong chin.  (2020).  modulation of leucine-rich-alpha-2-glycoprotein 1 (lrg1) promotes the survival of low-grade colorectal cancer via suppression of autophagy but not in high-grade cancer.  - gut.  A22. 

     

    shing cheng tan, poh ying lim, jie fang, mira farzana mohamad mokhtar, ezanee azlina mohamad hanif, rahman jamal.  (2020).  association between mir499a rs3746444 polymorphism and breast cancer susceptibility: a meta-analysis.  - scientific reports.  1-10. 

     

    mohd. firdaus che mat, ezanee azlina mohamad hanif, nor azian abdul murad, kamariah ibrahim, roslan harun, rahman jamal.  (2021).  silencing of zfp36l2 increases sensitivity to temozolomide through g2/m cell cycle arrest and bax mediated apoptosis in gbm cells.  - molecular biology reports.  1493-1503. 

     

    ezanee azlina mohamad hanif.  (2019).  dysregulation of non-histone molecule mir205 and lrg1 post-transcriptional de-regulation by setd1a in triple negative breast cancer..  - molecular biology reports.  6617-6624. 

     

    ezanee azlina mohamad hanif, shamsul azhar shah.  (2018).  overview on epigenetic re-programming: a potential therapeutic intervention in triple negative breast cancers.  - asian pacific journal of cancer prevention. 

     

    kha wai hon, norahayu othman, ezanee azlina mohamad hanif, siti nurmi nasir, nur syahada abd razak, rahman jamal, nadiah abu.  (2020).  drug resistance in colorectal cancer: molecular mechanisms and therapeutic strategies.  - 17. 

     

    ezanee azlina mohamad hanif.  (2020).  kromosom dan mekanisme gen: keupayaan diagnostik dalam pembentukan lesi/neoplasma tiroid.  - 74. 

     

    kha wai hon, norahayu othman, ezanee azlina mohamad hanif, siti nurmi nasir, nur syahada abd razak, rahman jamal, nadiah abu.  (2020).  drug resistance in colorectal cancer: molecular mechanisms and therapeutic strategies.  - 17. 

     

    siti aishah sulaiman, nor azian abdul murad, ezanee azlina mohamad hanif, nadiah abu, and rahman jamal.  (2018).  circular rna: biogenesis and function.  - 370. 

     

    ezanee azlina mohamad hanif.  (2020).  kromosom dan mekanisme gen: keupayaan diagnostik dalam pembentukan lesi/neoplasma tiroid.  - 74. 

     

    su min lim, ezanee azlina mohamad hanif, siok-fong chin.  (2020).  modulation of leucine-rich-alpha-2-glycoprotein 1 (lrg1) promotes the survival of low-grade colorectal cancer via suppression of autophagy but irreversible in high-grade cancer.  - international digestive disease forum (iddf) 2020.  1. 

     

    lim sm, mohamad hanif ea, chin s-f.  (2020).  overexpression of lrg1 supresses autophagy mechanism possible via tgfb superfamily in colorectal cancer.  - minggu penyelidikan perubatan & kesihatan ke-22.  1. 

     

    nurul nadiah ahmad daud, siok-fong chin, nor fadilah rajab, ezanee azlina mohamad hanif.  (2020).  deciphering cryptic intra-tumoral hallmark of tgfb isoforms in triple negative breast cancer (tnbc).  - 22nd medical and health research week 2020.  1. 

     

    ezanee azlina binti mohamad hanif;a. rahman bin a. jamal;amalia afzan binti saperi.  (2020).  identification of epithelial-to-mesenchymal-transition (emt) targets of epigenetic regulator setd1a in triple negative breast cancers (tnbcs)..  -

     

    afreena afiqah a, chin siok fong, norfadilah r, reena rahayu mz, rohaizak m, ezanee azlina mh.  (2020).  prediction of terminal differentiation induced non-coding rna (tincr) driver regulator in triple negative breast cancer..  - 22nd medical and health research week 2020.  1.