pensyarah universiti
institut biologi molekul perubatan ukm (umbi)
ezanee.azlina.mohamad.hanif@ppukm.ukm.edu.my
Kluster Kepakaran/ Cluster of Expertise :
Biografi/ Biography :
Dr. Ezanee received her first degree in University Malaya (Genetics & Molecular Biology), then carried on her passion in science by enrolling as a full-time Master student in the Faculty of Medicine, UKM. Her research then looking into chromosomal aberrations in thyroid neoplasms and was exposed in several molecular cytogenetic techniques (CGH, array-CGH) and BRCA1/ BRCA2 mutation detection in breast cancer (PCR, sequencing). Immediately after, Dr Ezanee joined as a tutor in UKM Medical Molecular Biology Institute (UMBI) (2008), then converted her post to Young research fellow (2009) upon receiving her Master degree (MMed.Sc. Pathology). In 2008-2012, she was involved in several projects such as the Genotyping XMEs in breast and cervical cancer, a genome-wide methylation analysis of breast and colorectal cancers and Diabetic GWAS, all utilising the microarray applications. She was involved in the Lab Accreditation MS ISO/IEC: 17025 as Technical Manager (2009-2011). In 2012, she pursued her Ph.D degree in Centre for Cancer Research and Cell Biology, Queen’s University Belfast, UK where she conducted research studying the underlying molecular mechanisms in driving poor prognosis in triple negative breast cancer (TNBC). In the UK, she was also the vice-president for the Malaysian Postgraduate in Northern Ireland (MyPNI) taking parts in group knowledge sharing and charity activities. She was conferred her Ph.D (Medicine) in 2017, a year after her viva voce. Upon returning, Dr Ezanee is actively applying for research grants and succeeded to obtain 3 research grants in triple negative breast cancer as principle investigator. She is also a co-researcher for 6 other projects related to her field and expertise. She is also actively involved in MS ISO/IEC 17025:2017 as Approved Signatory for HLA B*1502 genotyping in epilepsy and was part of the national emergency COVID-19 task force as Approved signatory. Dr Ezanee now has six students under her supervision both as main (2) and co-supervisor (4).
mohd razif shahril, nur afifah mursyida zaujan, suzana shahar, ezanee azlina mohamad hanif, rohaizak muhammad, fuad ismail, nur fa’izah ab muin, razinah sharif, ponnusamy subramaniam, azizi abdullah, michael fenech. (2024). the fitness-aging dilemma: how higher bmi modulates the accelerated aging effects of physical fitness on telomere length . - sicom-aoco (soms international conference on obesity & metabolism - asia oceania conference on obesity). 218 - 218.
muhammad-redha abdullah-zawawi, loscheni varma, muhammad irfan abdul jalal, ezanee azlina mohd hanif, shing cheng tan, seow neng chan, mohamad aimanuddin mohtar, rahman jamal. (2024). machine learning study to uncover critical prognostic factors affecting the survival probability of breast cancer patients using clinical and transcriptomics data. - translational and holistic medicine conference (transmec 2024). .
zenli cheng , ashok kumar janakiraman , baskaran gunasekaran , crystale lim siew ying , ezanee azlina binti mohamad hanif , hanish singh jayasingh chellammal , sinouvassane djearamane. (2024). unveiling the biomedical applications of zinc oxide (zno) nanoparticles: a review fostering on the synthesis, therapeutics and imaging with recent developments. - pharmaceutical sciences. 398 - 422.
ezanee azlina mohamad hanif, afreena afiqah azman, chin siok-fong, nor fadilah rajab, reena rahayu md zin, adi syazni mohammed, norlia abdullah, nani harlina md latar . (2024). functional characterisation and prognostic features of tincr in triple negative breast cancer. - 4th international conference on dental, medical & health sciences. .
ezanee azlina mohamad hanif, afreena afiqah azman, siok-fong chin, nor fadilah rajab, reena rahayu md zin, adi syazni mohammed, norlia abdullah, nani harlina md latar . (2024). tincr: the key regulator to chemoresistant in triple negative breast cancer (tnbc). - translational and holistic medicine conference 2024. .
fatimah audah md. zaki, ezanee azlina mohamad hanif. (2024). identifying mirna as biomarker for breast cancer subtyping using association rule. - computers in biology and medicine. 1 - 13.
lishantini pearanpan,fariza juliana nordin,ee ling siew ,endang kumolosasi,ezanee azlina mohamad hanif,siti fathiah masre,eng wee chua,hong sheng cheng,nor fadilah rajab. (2022). a cell-based systematic review on the role of annexin a1 in triple-negative breast cancers. - internation journal of molecular sciences. 1-16.
su min lim, ezanee azlina mohamad hanif, siok-fong chin. (2021). is targeting autophagy mechanism in cancer a good approach? the possible double-edge sword effect. - cell and bioscience. 1-13.
shing cheng tan, teck yew low, ezanee azlina mohamad hanif, mohamad ayub khan sharzehan, hamed kord-varkaneh & md asiful islam. (2021). the rs9340799 polymorphism of the estrogen receptor alpha (esr1) gene and its association with breast cancer susceptibility. - scientific reports. 18619.
muhammad nur adam hatta, ezanee azlina mohamad hanif, siok-fong chin, hui-min neoh. (2021). pathogens and carcinogenesis: a review. - biology. 1-22.
muhammad nur adam hatta; ezanee azlina mohamad hanif; siok-fong chin; teck yew low; hui-min neoh. (2023). parvimonas micra infection enhances proliferation, wound healing, and inflammation of a colorectal cancer cell line. - bioscience reports. 1-13.
afreena afiqah azman, chin siok fong, nor fadilah rajab, reena rahayu md zin, nurul nadiah ahmad daud, ezanee azlina mohamad hanif. (2023). the potential roles of lncrna tincr in triple negative breast cancer. - molecular biology reports. 7909-7917.
mohd. firdaus che mat, ezanee azlina mohamad hanif, nor azian abdul murad, kamariah ibrahim, roslan harun, rahman jamal. (2021). silencing of zfp36l2 increases sensitivity to temozolomide through g2/m cell cycle arrest and bax mediated apoptosis in gbm cells. - molecular biology reports. 1493-1503.
nor azila ma, nor azian am, azmawati mn, sharifah azura s, petrick p, najma k, mohd rohaizat h, norfazilah a, anita s, hanita o, tuti ningseh md, nurul syakima am, ezanee azlina, siti aishah, nurul syeefa', abdul rashid, abdul halim, hanafiah hr, rahman j. (2021). covid-19 in malaysia: exposure assessment and prevention practices among healthcare workers at a teaching hospital. - journal of infection in developing countries. 1816-1824.
ezanee azlina mohamad hanif. (2019). dysregulation of non-histone molecule mir205 and lrg1 post-transcriptional de-regulation by setd1a in triple negative breast cancer.. - molecular biology reports. 6617-6624.
fatimah audah md. zaki, ezanee azlina mohamad hanif. (2024). identifying mirna as biomarker for breast cancer subtyping using association rule. - computers in biology and medicine. 1 - 13.
zenli cheng , ashok kumar janakiraman , baskaran gunasekaran , crystale lim siew ying , ezanee azlina binti mohamad hanif , hanish singh jayasingh chellammal , sinouvassane djearamane. (2024). unveiling the biomedical applications of zinc oxide (zno) nanoparticles: a review fostering on the synthesis, therapeutics and imaging with recent developments. - pharmaceutical sciences. 398 - 422.
afreena afiqah azman, chin siok fong, nor fadilah rajab, reena rahayu md zin, nurul nadiah ahmad daud, ezanee azlina mohamad hanif. (2023). the potential roles of lncrna tincr in triple negative breast cancer. - molecular biology reports. 7909-7917.
muhammad nur adam hatta; ezanee azlina mohamad hanif; siok-fong chin; teck yew low; hui-min neoh. (2023). parvimonas micra infection enhances proliferation, wound healing, and inflammation of a colorectal cancer cell line. - bioscience reports. 1-13.
lishantini pearanpan,fariza juliana nordin,ee ling siew ,endang kumolosasi,ezanee azlina mohamad hanif,siti fathiah masre,eng wee chua,hong sheng cheng,nor fadilah rajab. (2022). a cell-based systematic review on the role of annexin a1 in triple-negative breast cancers. - internation journal of molecular sciences. 1-16.
kha wai hon, norahayu othman, ezanee azlina mohamad hanif, siti nurmi nasir, nur syahada abd razak, rahman jamal, nadiah abu. (2020). predictive biomarkers of drug resistance in colorectal cancer: recent updates. - . 135-151.
siti aishah sulaiman, nor azian abdul murad, ezanee azlina mohamad hanif, nadiah abu, and rahman jamal. (2018). prospective advances in circular rna investigation. - advances in experimental medicine and bi. 357-370.
ezanee azlina mohamad hanif. (2020). kromosom dan mekanisme gen: keupayaan diagnostik dalam pembentukan lesi/neoplasma tiroid. - . 74.
ezanee azlina mohamad hanif, afreena afiqah azman, chin siok-fong, nor fadilah rajab, reena rahayu md zin, adi syazni mohammed, norlia abdullah, nani harlina md latar . (2024). functional characterisation and prognostic features of tincr in triple negative breast cancer. - 4th international conference on dental, medical & health sciences. .
ezanee azlina mohamad hanif, afreena afiqah azman, siok-fong chin, nor fadilah rajab, reena rahayu md zin, adi syazni mohammed, norlia abdullah, nani harlina md latar . (2024). tincr: the key regulator to chemoresistant in triple negative breast cancer (tnbc). - translational and holistic medicine conference 2024. .
muhammad-redha abdullah-zawawi, loscheni varma, muhammad irfan abdul jalal, ezanee azlina mohd hanif, shing cheng tan, seow neng chan, mohamad aimanuddin mohtar, rahman jamal. (2024). machine learning study to uncover critical prognostic factors affecting the survival probability of breast cancer patients using clinical and transcriptomics data. - translational and holistic medicine conference (transmec 2024). .
nur afifah mursyida zaujan, mohd razif shahril, suzana shahar, ezanee azlina mohamad hanif, rohaizak muhammad, fuad ismail, nur fa’izah ab muin, razinah sharif, ponnusamy subramaniam, azizi abdullah, michael fenech. (2024). widespread cam adoption among malaysian breast cancer survivors and healthy women: a comparative insight. - 3rd macr international scientific conference . 30 - 30.
nur afifah mursyida zaujan, mohd razif shahril, suzana shahar, ezanee azlina mohamad hanif, rohaizak muhammad, fuad ismail, nur fa’izah ab muin, razinah sharif, ponnusamy subramaniam, azizi abdullah, michael fenech. (2024). active lives after cancer: a comparative analysis of physical activity in breast cancer survivors and healthy controls . - 14th international symposium of health sciences. 107 - 107.
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| DECIPHERING THE INTER-LINKAGE ROLE OF VITAMIN D AND LEUCINE-RICH α-2 GLYCOPROTEIN 1 (LRG1) IN 5-FLUOROURACIL CHEMORESISTANT COLORECTAL CANCER: A CLINICAL ASSESSMENT | bio-diagnostic sdn bhd | 82.1% (2023-10-01 sehingga 2026-03-31) |
| THE CORRELATION OF PD-L1 POSITIVITY WITH DNA MISMATCH REPAIR AND THEIR ASSOCIATIONS WITH TUMOUR-INFILTRATING LYMPHOCYTES IN TRIPLE NEGATIVE BREAST CANCER PATIENTS | biomarketing services (m) sdn. bhd. | 48.3% (2024-11-01 sehingga 2026-10-31) |
| THE CORRELATION OF PD-L1 POSITIVITY WITH DNA MISMATCH REPAIR AND THEIR ASSOCIATIONS WITH TUMOUR-INFILTRATING LYMPHOCYTES IN TRIPLE NEGATIVE BREAST CANCER PATIENTS | jabatan patologi, hospital putrajaya | 48.3% (2024-11-01 sehingga 2026-10-31) |
BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
Cancer Biology (Breast cancer)
Pengalaman / Experience : 11 tahun/years(s)
HEALTH SCIENCES :CLINICAL AND HEALTH SCIENCES
Cancer Biology (disease regulation and mechanism)
Pengalaman / Experience : 7 tahun/years(s)
BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
Genes / proteins functional roles and molecular mechanisms of diseases (especially breast and colorectal cancer)
Pengalaman / Experience : 10 tahun/years(s)
CLINICAL MEDICAL :CLINICAL AND HEALTH SCIENCES
Triple negative breast cancer driver mechanism
Pengalaman / Experience : 7 tahun/years(s)