prof. madya dr. ng min hwei

pensyarah universiti

pusat kajian kejuruteraan tisu & perubatan regeneratif

 angela@ppukm.ukm.edu.my



   Biografi/ Biography :

  • Prof. Dr. Angela Min Hwei Ng telah memperoleh Ijazah Sarjana Muda dalam Bioteknologi dari Universiti Putra Malaysia. Beliau kemudian memperoleh Ijazah Sarjana di bawah penyeliaan dua ahli Patologi terkemuka, Prof. Dr. Looi Lai Meng dan Prof. Dr. Cheah Phaik Leng di Universiti Malaya, mengkaji hubungan telomeras dan panjang telomer dengan keagresifan kanser dan keabadian sel. Di bawah bimbingan Prof. Ruszymah Idrus, seorang Profesor terkemuka dalam Fisiologi di Universiti Kebangsaan Malaysia, Angela mengejar PhD dalam kejuruteraan tisu & perubatan regeneratif di mana beliau merevolusikan pelbagai pendekatan dalam regenerasi tulang termasuk pembangunan tulang suntikan, fabrikasi gantian tulang 3D kompleks dan pembaharuan sel punca dari pesakit yang sudah tua melalui ekspresi telomeras eksogen. Angela kini merupakan Seorang Ahli Penyelidik dan Ketua Pusat Kejuruteraan Tisu di Pusat Perubatan Universiti Kebangsaan Malaysia. Pengalamannya dalam kejuruteraan tisu dan penyelidikan regeneratif merangkumi pelbagai tisu termasuk tulang, kartilaj, saraf, jantung, pundi kencing dan kornea. Kerja luasnya selama 10 tahun yang lalu telah menghasilkan beberapa produk inovatif yang telah memenangi anugerah terkemuka dalam pameran tempatan dan antarabangsa. Sehingga kini, beliau telah mengemukakan 5 paten dan lebih dari 60 artikel yang diterbitkan. Fokus penyelidikan terkini beliau termasuk pembuatan cepat kerangka 3D, kejuruteraan tisu berpembuluh, dan terapi berasaskan sel dan eksosom. Beliau juga aktif terlibat dalam translasi klinikal. Beliau mempunyai pengalaman langsung dalam menubuhkan fasiliti GMP untuk produk sel & tisu; dari konsepsi susunan fasiliti hingga pembangunan sistem kualiti, latihan kakitangan dan menjalankan ujian klinikal.
    Assoc. Prof. Dr. Angela Min Hwei Ng obtained her Bachelor’s Degree in Biotechnology from Universiti Putra Malaysia. She then obtained her Master’s degree under the supervision of two distinguished Pathologists, Prof. Dr. Looi Lai Meng and Prof. Dr. Cheah Phaik Leng in Universiti Malaya studying on the association of telomerase and telomere length with cancer aggressiveness and cell immortality. Under the guidance of Prof Ruszymah Idrus, a notable Professor in Physiology in Universiti Kebangsaan Malaysia, Angela pursued her PhD in tissue engineering & regenerative medicine whereby she revolutionized different approaches in bone regeneration including developing an injectable bone, fabrication of complex 3D bone substitutes and rejuvenation of stem cells from elderly patients via exogenous telomerase expression. Angela is currently a Research Fellow and the Head of Tissue Engineering Centre in Universiti Kebangsaan Malaysia Medical Centre. Her experience in tissue engineering and regenerative research covers various tissues including bone, cartilage, nerve, heart, bladder and cornea. Her extensive work over the past 10 years has resulted in several innovative products which have won her distinguished awards in local and international expositions. To date, she has 5 patents filed and over 60 publications published. Her current research focus includes 3D scaffold rapid prototyping, engineering vascularized tissues, and cell and exosome-based therapies. She is also actively involved in clinical translation. She has first-hand experience on establishing a GMP facility for cell & tissue products; from the conception of the facility layout to developing the quality system, training of personnel and running of a clinical trial.

  • nur amalia ra'oh, rohaina che man, mh busra fauzi, norzana abd ghafar, muhamad ramdzan buyong, ng min hwei and wan haslina wan abdul halim.  (2023).  recent approaches to the modification of collagen biomatrix as a corneal biomatrix and its cellular interaction.  - polymers.  1-36. 

     

    izyan mohd idris, fazlina nordin, nur jannaim muhamad, julaina abdul jalil, fatimah diana amin nordin, rosnani mohamed, adiratna mat ripen, gee jun tye, wan safwani wan kamarul zaman, muhammad dain yazid & min hwei ng.  (2023).  the establishment of in-vitro human induced pluripotent stem cell-derived neurons.  - sains malaysiana.  849-862. 

     

    chee-yin wong, angela min hwei ng, yang-mooi lim, and soon-keng cheong.  (2023).  editorial: stem cell regeneration strategies in treating kidney diseases: from mechanisms to therapeutics.  - frontiers in cell and developmental biology.  1-2. 

     

    yogeswaran lokanathan, alvin chan man lung, angela ng min hwei, mohd heikal mohd yunus, ruszymah hj idrus, law jia xian, muhammad dain yazid, chin kok yong, sharen aini shamsuddin, rafizul mohd yusof, rabiatul adawiyah razali, mohd asyraf.  (2023).  allogeneic wharton's jelly-derived mesenchymal stem cell as cell therapy: safety study in an animal model.  - international conference on molecular medicine and therapeutics (icmt-2023).  1. 

     

    yogeswaran lokanathan, anam anjum, muhammad dain yazid, muhammad fauzi daud, min hwei ng, amaramalar selvi naicker, ohnmar htwe ismail, ramesh kumar athi kumar, jalilah idris.  (2023).  kainic acid excitotoxicity induced chemical spinal cord injury in vivo model for assessment of neuroregeneration potential of drugs.  - tissue engineering and regenerative medicine international society (termis) european chapter meeting 2023.  PP408. 

     

    alvin man lung chan, jin min cheah, yogeswaran lokanathan, min hwei ng, jia xian law.  (2023).  natural killer cell-derived extracellular vesicles as a promising immunotherapeutic strategy for cancer: a systematic review.  - international journal of molecular sciences.  1-24. 

     

    revatyambigai subramaniam, ubashini vijakumaran, lohashenpahan shanmuganantha, jia-xian law, ekram alias and min-hwei ng.  (2023).  the role and mechanism of microrna 21 in osteogenesis: an update.  - international journal of molecular sciences.  1-28. 

     

    benson koh, nadiah sulaiman, mohd fauzi mh busra, law jia xian, ng min hwei, too lih yuan, abdul ghani nur azurah, mohd heikal mohd yunus, ruszymah bt hj idrus, muhammad dain yazid..  (2023).  a three-dimensional xeno-free culture condition for wharton's jelly-mesenchymal stem cells: the pros and cons.  - international journal of molecular sciences.  1-18. 

     

    wan tai seet, mohd asyraf mat afandi, mohamad fikeri ishak, muhammad najib fathi hassan, nazeha ahmat, min hwei ng and manira maarof.  (2023).  quality management overview for the production of a tissue-engineered human skin substitute in malaysia.  - stem cell research & therapy.  1-14. 

     

    nur amalia ra'oh, rohaina che man, mh busra fauzi, norzana abd ghafar, muhamad ramdzan buyong, ng min hwei and wan haslina wan abdul halim.  (2023).  recent approaches to the modification of collagen biomatrix as a corneal biomatrix and its cellular interaction.  - polymers.  1-36. 

     

    izyan mohd idris, fazlina nordin, nur jannaim muhamad, julaina abdul jalil, fatimah diana amin nordin, rosnani mohamed, adiratna mat ripen, gee jun tye, wan safwani wan kamarul zaman, muhammad dain yazid & min hwei ng.  (2023).  the establishment of in-vitro human induced pluripotent stem cell-derived neurons.  - sains malaysiana.  849-862. 

     

    shamsul sulaiman, rizal abdul rani, nor hamdan mohamad yahaya, yasuhiko tabata, yosuke hiraoka, wan tai seet, min hwei ng.  (2022).  physical and natural crosslinking approaches on three-dimensional gelatin microspheres for cartilage regeneration.  - tissue engineering part c.  557-569. 

     

    sook y. looi, mae-lynn c bastion, sue n leow, chi d luu, n mh hairul, raduan ruhaslizan, hon s wong, abdul h wan haslina, min h ng, b hj idrus ruszymah, kong y then.  (2022).  therapeutic potential of human umbilical cord-derived mesenchymal stem cells transplantation in rats with optic nerve injury.  - indian journal of ophthalmology.  201-209. 

     

    munirah abd rashid, lam chenshen, avin koh ee hwan, hiba alsaeedy, pooi ling mok, suresh kumar subbiah, hazlita md isa, then kong yong, mohd hairul nizam harun, syed mohamed suhail b s mohamad, angela ng min hwei, chi d luu, mae-lynn.  (2022).  rescue of photoreceptor with human mesenchyme stem cell and human mesenchyme stem cell expressing erythropoietin in total degeneration of retina animal model.  - indian journal of ophthalmology.  921-929. 

     

    muhammad najib fathi bin hassan, yap zheng yie, tang yee loong, ng min hwei, law jia xian.  (2021).  expired platelet concentrates as a source of human platelet lysate for xenogeneic-free culture of human skin fibroblasts.  - sains malaysiana.  2355-2365. 

     

    benson koh, nadiah sulaiman, mohd fauzi mh busra, law jia xian, ng min hwei, too lih yuan, abdul ghani nur azurah, mohd heikal mohd yunus, ruszymah bt hj idrus, muhammad dain yazid..  (2023).  a three-dimensional xeno-free culture condition for wharton's jelly-mesenchymal stem cells: the pros and cons.  - international journal of molecular sciences.  1-18. 

     

    alvin man lung chan, jin min cheah, yogeswaran lokanathan, min hwei ng, jia xian law.  (2023).  natural killer cell-derived extracellular vesicles as a promising immunotherapeutic strategy for cancer: a systematic review.  - international journal of molecular sciences.  1-24. 

     

    revatyambigai subramaniam, ubashini vijakumaran, lohashenpahan shanmuganantha, jia-xian law, ekram alias and min-hwei ng.  (2023).  the role and mechanism of microrna 21 in osteogenesis: an update.  - international journal of molecular sciences.  1-28. 

     

    nur amalia ra'oh, rohaina che man, mh busra fauzi, norzana abd ghafar, muhamad ramdzan buyong, ng min hwei and wan haslina wan abdul halim.  (2023).  recent approaches to the modification of collagen biomatrix as a corneal biomatrix and its cellular interaction.  - polymers.  1-36. 

     

    wan tai seet, mohd asyraf mat afandi, mohamad fikeri ishak, muhammad najib fathi hassan, nazeha ahmat, min hwei ng and manira maarof.  (2023).  quality management overview for the production of a tissue-engineered human skin substitute in malaysia.  - stem cell research & therapy.  1-14. 

     

    siti saniah ab. karim, abu bakar sulong, che husna azhari, ng min hwei and mohd reusmaazran yusof.  (2011).  influence of polyacrilonitrile (pan) concentration on the mechanical and physical properties of electrospun fibres.  - key engineering materials. 

     

    yogeswaran lokanathan, angela ng min hwei.  (2023).  sustainable material for biomedical engineering application.  - 17. 

     

    yong sheng tan, qi hao looi, nadiah sulaiman, min hwei ng, jia xian law.  (2022).  handbook of stem cell therapy.  - 30. 

     

    abu bakar sulong, angela ng min hwei ng, muhammad azmi abdul hamid.  (2021).  metal-ceramic composite: a new generation material for medical implant.  - 135. 

     

    ling ling liau, qi hao looi, sue ping eng, muhammad dain yazid, nadiah sulaiman, mohd fauzi mh busra, min hwei ng, jia xian law.  (2020).  stem cells: from hype to hope.  - 33. 

     

    yogeswaran lokanathan, angela ng min hwei.  (2023).  sustainable material for biomedical engineering application.  - 17. 

     

    mh busra fauzi, jia xian law, min hwei ng, yogeswaran lokanathan, nadiah sulaiman, and atiqah salleh.  (2022).  food, medical, and environmental applications of nanomaterials.  - 24. 

     

    wan tai seet, mohd asyraf mat afandi, sharen aini shamsuddin, yogeswaran lokanathan, min hwei ng, manira maarof.  (2022).  stem cell production - processes, practices and regulations.  - 32. 

     

    yong sheng tan, qi hao looi, nadiah sulaiman, min hwei ng, jia xian law.  (2022).  handbook of stem cell therapy.  - 30. 

     

    ling ling liau, qi hao looi, sue ping eng, muhammad dain yazid, nadiah sulaiman, mohd fauzi mh busra, min hwei ng, jia xian law.  (2020).  stem cells: from hype to hope.  - 33. 

     

    abu bakar sulong, angela ng min hwei ng, muhammad azmi abdul hamid.  (2021).  metal-ceramic composite: a new generation material for medical implant.  - 135. 

     

    ekram bin alias;norazlina binti mohamed;nor hamdan bin mohamad yahaya;mohd hanafi bin ahmad damanhuri;ng min hwei;tan jen kit;wan zurinah wan ngah (prof. dr.).  (2023).  study on cellular energy metabolism and mitochondrial respiration of osteoclasts induced by polyethylene for the development of pet-ct diagnostic application for peri-prosthetic osteolysis.  -

     

    abu bakar bin sulong;muhammad azmi bin abdul hamid;ng min hwei;farah `atiqah binti abdul azam.  (2023).  a new generation of titanium/hydroxyapatite/wollastonite biocomposite material for orthopaedic implant.  -

     

    mohd fauzi bin mh busra;ng min hwei.  (2023).  fabrication and characterisation of 3d bioscaffold via 3d-bioprinting approach for skin tissue engineering: gelatin vs collagen bioinks .  -

     

    law jia xian;ng min hwei;yogeswaran a/l lokanathan.  (2023).  elucidate the mirna profile of exosomes secreted by wharton’s jelly-derived mesenchymal stem cells at early and late passages.  -

     

    yogeswaran a/l lokanathan;amaramalar selvi naicker;ohnmar htwe @ rashidah binti ismail;brenda saria binti yuliawiratman;ng min hwei;ramesh kumar a/l athi kumar;muhammad da`in bin yazid.  (2023).  effect of neuroaid (mlc 901) on spinal cord regeneration in in vivo spinal cord injury model and its mechanism of action.  -

     
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