pensyarah universiti
jabatan kejuruteraan tisu & perubatan regeneratif
angela@ppukm.ukm.edu.my
Biografi/ Biography :
Prof. Dr. Angela Min Hwei Ng telah memperoleh Ijazah Sarjana Muda dalam Bioteknologi dari Universiti Putra Malaysia. Beliau kemudian memperoleh Ijazah Sarjana di bawah penyeliaan dua ahli Patologi terkemuka, Prof. Dr. Looi Lai Meng dan Prof. Dr. Cheah Phaik Leng di Universiti Malaya, mengkaji hubungan telomeras dan panjang telomer dengan keagresifan kanser dan keabadian sel. Di bawah bimbingan Prof. Ruszymah Idrus, seorang Profesor terkemuka dalam Fisiologi di Universiti Kebangsaan Malaysia, Angela mengejar PhD dalam kejuruteraan tisu & perubatan regeneratif di mana beliau merevolusikan pelbagai pendekatan dalam regenerasi tulang termasuk pembangunan tulang suntikan, fabrikasi gantian tulang 3D kompleks dan pembaharuan sel punca dari pesakit yang sudah tua melalui ekspresi telomeras eksogen. Angela kini merupakan Seorang Ahli Penyelidik dan Ketua Pusat Kejuruteraan Tisu di Pusat Perubatan Universiti Kebangsaan Malaysia. Pengalamannya dalam kejuruteraan tisu dan penyelidikan regeneratif merangkumi pelbagai tisu termasuk tulang, kartilaj, saraf, jantung, pundi kencing dan kornea. Kerja luasnya selama 10 tahun yang lalu telah menghasilkan beberapa produk inovatif yang telah memenangi anugerah terkemuka dalam pameran tempatan dan antarabangsa. Sehingga kini, beliau telah mengemukakan 5 paten dan lebih dari 60 artikel yang diterbitkan. Fokus penyelidikan terkini beliau termasuk pembuatan cepat kerangka 3D, kejuruteraan tisu berpembuluh, dan terapi berasaskan sel dan eksosom. Beliau juga aktif terlibat dalam translasi klinikal. Beliau mempunyai pengalaman langsung dalam menubuhkan fasiliti GMP untuk produk sel & tisu; dari konsepsi susunan fasiliti hingga pembangunan sistem kualiti, latihan kakitangan dan menjalankan ujian klinikal.
Assoc. Prof. Dr. Angela Min Hwei Ng obtained her Bachelor’s Degree in Biotechnology from Universiti Putra Malaysia. She then obtained her Master’s degree under the supervision of two distinguished Pathologists, Prof. Dr. Looi Lai Meng and Prof. Dr. Cheah Phaik Leng in Universiti Malaya studying on the association of telomerase and telomere length with cancer aggressiveness and cell immortality. Under the guidance of Prof Ruszymah Idrus, a notable Professor in Physiology in Universiti Kebangsaan Malaysia, Angela pursued her PhD in tissue engineering & regenerative medicine whereby she revolutionized different approaches in bone regeneration including developing an injectable bone, fabrication of complex 3D bone substitutes and rejuvenation of stem cells from elderly patients via exogenous telomerase expression. Angela is currently a Research Fellow and the Head of Tissue Engineering Centre in Universiti Kebangsaan Malaysia Medical Centre. Her experience in tissue engineering and regenerative research covers various tissues including bone, cartilage, nerve, heart, bladder and cornea. Her extensive work over the past 10 years has resulted in several innovative products which have won her distinguished awards in local and international expositions. To date, she has 5 patents filed and over 60 publications published. Her current research focus includes 3D scaffold rapid prototyping, engineering vascularized tissues, and cell and exosome-based therapies. She is also actively involved in clinical translation. She has first-hand experience on establishing a GMP facility for cell & tissue products; from the conception of the facility layout to developing the quality system, training of personnel and running of a clinical trial. She is committed to advocating regenerative medicine as a sustainable healthcare practice and have been involved in drafting guidelines and policy for the Malaysian Medical Association in governing the practice of stem cell therapy and regenerative medicine.
muhammad najib fathi hassan, muhammad dain yazid, mohd heikal bin mohd yunus, yogeswaran lokanathan, min hwei ng, ruszymah bt hj idrus, yee loong tang, see nguan ng, jia xian law. (2025). comparing the growth kinetics and characteristics of wharton’s jelly derived mesenchymal stem cells expanded using different culture mediums. - cytotechnology. 1 - 16.
li ting kee, jhi biau foo, chee wun how, abdul ghani nur azurah, hong hao chan, mohd heikal mohd yunus, see nguan ng, min hwei ng, jia xian law. (2025). umbilical cord mesenchymal stromal cell-derived small extracellular vesicles modulate skin matrix synthesis and pigmentation. - international journal of nanomedicine. 1561 - 1578.
illayaraja krishnan, magdalene tan mei ling , min hwei ng, jia xian law, mohd rafizul mohd yusof, thavachelvi thangarajah , zalina mahmood , nurul izzati uda zahli , shathiya rajamanickam , baskar subramani and yogeswaran lokanathan. (2025). efficacy of fetal wharton’s jelly mesenchymal stem cells-derived small extracellular vesicles in metabolic syndrome. - biomolecules. 1 - 29.
bo ma, muttiah barathan, min hwei ng, jia xian law. (2025). oxidative stress, gut microbiota, and extracellular vesicles: interconnected pathways and therapeutic potentials. - international journal of molecular sciences. 1 - 25.
illayaraja krishnan, ubashini vijakumaran, min hwei ng, jia xian law, mohd rafizul mohd yusof, thavachelvi thangarajah, geok chin tan, yin ping wong, anusha kalyanasundaram, zalina mahmood, shathiya rajamanickam, baskar subramani, yogeswaran lokanathan. (2025). safety evaluation and biodistribution of fetal umbilical cord mesenchymal stem cells-derived small extracellular vesicles in sprague dawley rats. - international journal of molecular sciences. 1 - 21.
li ting kee, jhi biau foo, chee wun how, abdul ghani nur azurah, hong hao chan, mohd heikal mohd yunus, see nguan ng, min hwei ng, jia xian law. (2025). umbilical cord mesenchymal stromal cell-derived small extracellular vesicles modulate skin matrix synthesis and pigmentation. - international journal of nanomedicine. 1561 - 1578.
illayaraja krishnan, magdalene tan mei ling , min hwei ng, jia xian law, mohd rafizul mohd yusof, thavachelvi thangarajah , zalina mahmood , nurul izzati uda zahli , shathiya rajamanickam , baskar subramani and yogeswaran lokanathan. (2025). efficacy of fetal wharton’s jelly mesenchymal stem cells-derived small extracellular vesicles in metabolic syndrome. - biomolecules. 1 - 29.
bo ma, muttiah barathan, min hwei ng, jia xian law. (2025). oxidative stress, gut microbiota, and extracellular vesicles: interconnected pathways and therapeutic potentials. - international journal of molecular sciences. 1 - 25.
nur hakimin bin md noorpi, mohd yazid bin bajuri, norliyana binti mazli, ruszymah binti hj idrus, angela ng min hwei & jia xian law . (2025). a prospective single center non randomized clinical trial of autologous skin cells with platelet rich plasma for diabetic ulcer and trauma injuries patients. - scientific reports. 1 - 8.
vick key tew, muttiah barathan, fazlina nordin, jia xian law, min hwei ng . (2025). emerging role of mesenchymal stromal cell and exosome therapies in treating cognitive impairment. - pharmaceutics. 1 - 24.
muhammad najib fathi hassan, muhammad dain yazid, mohd heikal bin mohd yunus, yogeswaran lokanathan, min hwei ng, ruszymah bt hj idrus, yee loong tang, see nguan ng, jia xian law. (2025). comparing the growth kinetics and characteristics of wharton’s jelly derived mesenchymal stem cells expanded using different culture mediums. - cytotechnology. 1 - 16.
izyan mohd idris, fazlina nordin, nur jannaim muhamad, siti zuleha idris, gee jun tye, wan safwani wan kamarul zaman & min hwei ng. (2024). evaluation of lentiviral based gene delivery system in adherent and suspension in vitro cell models. - sains malaysiana. 549-559.
izyan mohd idris, fazlina nordin, nur jannaim muhamad, julaina abdul jalil, fatimah diana amin nordin, rosnani mohamed, adiratna mat ripen, gee jun tye, wan safwani wan kamarul zaman, muhammad dain yazid & min hwei ng. (2023). the establishment of in-vitro human induced pluripotent stem cell-derived neurons. - sains malaysiana. 849-862.
munirah abd rashid, lam chenshen, avin koh ee hwan, hiba alsaeedy, pooi ling mok, suresh kumar subbiah, hazlita md isa, then kong yong, mohd hairul nizam harun, syed mohamed suhail b s mohamad, angela ng min hwei, chi d luu, mae-lynn. (2022). rescue of photoreceptor with human mesenchyme stem cell and human mesenchyme stem cell expressing erythropoietin in total degeneration of retina animal model. - indian journal of ophthalmology. 921-929.
shamsul sulaiman, rizal abdul rani, nor hamdan mohamad yahaya, yasuhiko tabata, yosuke hiraoka, wan tai seet, min hwei ng. (2022). physical and natural crosslinking approaches on three-dimensional gelatin microspheres for cartilage regeneration. - tissue engineering part c. 557-569.
bo ma, muttiah barathan, min hwei ng, jia xian law. (2025). oxidative stress, gut microbiota, and extracellular vesicles: interconnected pathways and therapeutic potentials. - international journal of molecular sciences. 1 - 25.
nur hakimin bin md noorpi, mohd yazid bin bajuri, norliyana binti mazli, ruszymah binti hj idrus, angela ng min hwei & jia xian law . (2025). a prospective single center non randomized clinical trial of autologous skin cells with platelet rich plasma for diabetic ulcer and trauma injuries patients. - scientific reports. 1 - 8.
vick key tew, muttiah barathan, fazlina nordin, jia xian law, min hwei ng . (2025). emerging role of mesenchymal stromal cell and exosome therapies in treating cognitive impairment. - pharmaceutics. 1 - 24.
muhammad najib fathi hassan, muhammad dain yazid, mohd heikal bin mohd yunus, yogeswaran lokanathan, min hwei ng, ruszymah bt hj idrus, yee loong tang, see nguan ng, jia xian law. (2025). comparing the growth kinetics and characteristics of wharton’s jelly derived mesenchymal stem cells expanded using different culture mediums. - cytotechnology. 1 - 16.
maimonah eissa al-masawa, loai a elfawy, chiew yong ng, min hwei ng, jia xian law. (2025). mesenchymal stromal cell-derived extracellular vesicles in the management of atopic dermatitis: a scoping review of therapeutic opportunities and challenges. - international journal of nanomedicine. 2673 - 2693.
siti saniah ab. karim, abu bakar sulong, che husna azhari, ng min hwei and mohd reusmaazran yusof. (2011). influence of polyacrilonitrile (pan) concentration on the mechanical and physical properties of electrospun fibres. - key engineering materials. .
jia xian law, min hwei ng, yogeswaran lokanathan, alvin man lung chan, jin min cheah. (2025). current progress and challenges of nongenetically modified natural killer (nk) cell-based immunotherapy. - . 314 - 325.
lim wei lee, zahra rashidbenam, genieve ee chia yeo, min hwei ng, jia xian law. (2024). chapter 3: cell sheet technology for tendon and ligament tissue engineering. - . 30-49.
yogeswaran lokanathan, angela ng min hwei, mohd heikal mohd yunus, ruszymah haji idrus & daniel lee eng shen. (2024). terapi sel dan sindrom metabolik. - . 61 - 72.
yogeswaran lokanathan, angela ng min hwei. (2023). ethical and regulatory considerations for sustainable practices in biomedical applications. - . 483-499.
wan tai seet, mohd asyraf mat afandi, sharen aini shamsuddin, yogeswaran lokanathan, min hwei ng, manira maarof. (2022). current good manufacturing practice (cgmp) facility and production of stem cell. - . 37-68.
law jia xian, kee li ting, foo jhi biau, how chee wun, nur azurah abdul ghani, chan hong hao, mohd heikal bin mohd yunus, ng see nguan, ng min hwei. (2024). meremajakan kulit menggunakan vesikel ekstrasel terbitan sel stem. - research medicine innovation. .
song see lee, lohashenpahan shanmuganantha, abu bakar sulong, mohd reusmaazran yusof, muhammad azmi abdul hamid, rahimi l. muhamud, ng min hwei*. (2024). fabrikasi dan pencirian kerangka 3d polimer-bioseramik berliang untuk aplikasi kejuruteraan tisu. - jurnal kejuruteraan. 847 - 859.
muttiah barathan, sook luan ng, yogeswaran lokanathan, min hwei ng, jia xian law. (2024). peranan dual vesikel ekstraselular dalam kanser: potensi untuk terapi dan sumbangan kepada rintangan dan metastasis. - research medicine innovation. .
yogeswaran lokanathan, angela ng min hwei, mohd heikal mohd yunus, ruszymah haji idrus & daniel lee eng shen. (2024). terapi sel dan sindrom metabolik. - . 61 - 72.
abu bakar bin sulong;muhammad azmi bin abdul hamid;ng min hwei;farah `atiqah binti abdul azam. (2023). a new generation of titanium/hydroxyapatite/wollastonite biocomposite material for orthopaedic implant. - . .
manira binti maarof;ng shiow fern;ng min hwei;mohd fauzi bin mh busra;nurwahyuna binti rosli;mohd asyraf bin mat afandi;yogeswaran a/l lokanathan. (2024). shelf-life and safety evaluation of the dermal fibroblast conditioned medium (dfcm) for future skin regeneration and rejuvenation. - . .
yogeswaran a/l lokanathan;ruszymah binti haji idrus;norazlina binti mohamed;mohd heikal bin mohd yunus;shamsul azhar bin shah;anis ezdiana binti abdul aziz;ng min hwei;shiplu roy chowdhury;muhammad da`in bin yazid;chow yock ping;chin kok yong;law jia xian. (2024). program: identifying degenerative disease burden among elderly population in klang valley and innovative intervention modalities. sub project: animal study on the safety and efficacy of allogeneic mesenchymal stromal/ stem cell therapy in delaying the pr. - . .
yogeswaran a/l lokanathan;mohd rafizul bin mohd yusof;mohd heikal bin mohd yunus;ng min hwei;muhammad da`in bin yazid;chin kok yong;law jia xian;sharen @ sharen aini binti shamsuddin;mohd asyraf bin mat afandi;rabiatul adawiyah binti razali. (2024). efficacy study of allogeneic mesenchymal stem cell therapy for treatment for metabolic syndrome in animal model. - . .
law jia xian, kee li ting, foo jhi biau, how chee wun, nur azurah abdul ghani, chan hong hao, mohd heikal bin mohd yunus, ng see nguan, ng min hwei. (2024). meremajakan kulit menggunakan vesikel ekstrasel terbitan sel stem. - research medicine innovation. .
zahrina haziqah binti harun, angela ng min hwei, shalimar abdullah. (2024). the role of aligned nanofibers of nerve conduit seeded with schwann-cell like cells in modulating neuropathic pain and inflammation. - med & health apr 2024; 19(2) (suppl): 01-31. 24 - 24.
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| INVESTIGATING THE GUT-LUNG AXIS INTERACTION OF LIGNOSUS RHINOCEROTIS (TIGER MILK MUSHROOM) IN REDUCING COUGH AND LUNG INFLAMMATION | nexus wise sdn bhd | 56.7% (2024-01-31 sehingga 2026-12-31) |
| REDUCED GRAPHENE OXIDE/POLYANILINE POLYMER MATRIX WITH ENHANCED ELECTRICAL CONDUCTIVITY | yakin splendour global holding berhad | 79.6% (2023-10-01 sehingga 2026-03-31) |
| DEVELOPMENT OF NK92 AND ITS DERIVATIVES AS AN ALLOGENEIC NK CELL THERAPY FOR THE TREATMENT OF CANCER | ming medical sdn. bhd. | 82.9% (2024-01-30 sehingga 2026-01-29) |
| HESCS-DERIVED AND IPSCS-DERIVED EXOSOMES: THE POTENTIAL FOR THERAPEUTIC APPROACHES | ming medical sdn. bhd. | 76.1% (2024-03-20 sehingga 2026-03-19) |
| EFFECT OF MESENCHYMAL STEM CELL SECRETION ON IMPROVING EMBRYO QUALITY | shenzhen university | 48.3% (2024-04-16 sehingga 2027-04-15) |
| THE EFFECT AND MECHANISM OF ACTION OF EXOSOMES ON HUMAN TELOMERE LENGTH & BIOENERGETICS | ming medical sdn. bhd. | 48.3%(2024-08-15 sehingga 2026-08-14) |
| ELUCIDATING THE EFFECTS OF MESENCHYMAL STEM CELL TRANSPLANTATION ON COGNITIVE FUNCTION OF AGEING MICE | regena asia sdn bhd | 48.3%(2022-12-01 sehingga 2026-09-30) |
| EXPLORING PERIPHERAL BLOOD MONONUCLEAR CELLS- DERIVED OSTEOCLASTS AS A SOURCE OF HIGHLY ACTIVE MITOCHONDRIA FOR TRANSFER INTO CARDIOMYOCYTES FOR THE TREATMENT OF ISCHEMIC HEART DISEASE | mrc-mitochondrial biology unit, the university of cambridge | 48.3%(2024-11-01 sehingga 2026-10-31) |