pegawai penyelidik
jabatan patologi
nurmayasabrina@ukm.edu.my
Kluster Kepakaran/ Cluster of Expertise :
Biografi/ Biography :
Nur Maya Sabrina Tizen Laim ialah Pegawai Penyelidik di Jabatan Patologi, Fakulti Perubatan, Universiti Kebangsaan Malaysia (UKM) dan telah berkhidmat sejak tahun 2009. Beliau memperoleh Ijazah Sarjana Muda Sains dengan Kepujian dalam bidang Genetik dari UKM pada tahun 2007 dan seterusnya menamatkan pengajian Sarjana Sains Perubatan dalam bidang Patologi dari institusi yang sama pada tahun 2021.
Dengan lebih daripada satu dekad pengalaman dalam bidang patologi, penyelidikan beliau banyak memberi tumpuan kepada perubatan makmal khususnya dalam bidang histologi, histopatologi dan genetik molekul. Bidang penyelidikannya merangkumi pelbagai jenis kanser seperti limfoma, kanser payudara, kanser kolorektal serta tumor pepejal yang lain.
Beliau telah terlibat secara aktif dalam pelbagai projek penyelidikan dan kolaborasi, menyumbang kepada penerbitan jurnal yang mengkaji penanda biomolekul kanser, persekitaran mikro tumor, serta aplikasi teknik seperti imunohistokimia (IHC), imunofluoresens (IF), dan tisu mikroarray (TMA). Hasil penyelidikannya sering menjurus ke arah penggabungan antara diagnostik klinikal dan penyelidikan translasi, dengan minat khas terhadap penggunaan kaedah pewarnaan lanjutan dan pemprofilan molekul bagi meningkatkan ketepatan diagnosis dan penilaian prognosis.
Dalam beberapa tahun kebelakangan ini, beliau turut menunjukkan minat yang semakin mendalam terhadap patologi digital, khususnya dalam potensinya untuk analisis penanda kanser dan sokongan diagnostik berasaskan imej, sejajar dengan perkembangan semasa dalam perubatan presisi. Sumbangan beliau mencerminkan komitmen tinggi dalam memajukan penyelidikan kanser melalui pendekatan makmal yang inovatif dan praktikal.
Nur Maya Sabrina Tizen Laim is a Research Officer at the Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), where she has served since 2009. She holds a Bachelor of Science with Honours in Genetics from UKM (2007) and earned her Master of Medical Science in Pathology from the same institution in 2021.
With over a decade of experience in the field of pathology, her research has centered on laboratory medicine—particularly in the areas of histology, histopathology, and molecular genetics. Her work has contributed significantly to the understanding of various malignancies, with a primary focus on lymphoma, breast cancer, colorectal cancer, and other solid tumors.
She has been actively involved in numerous research projects and collaborations, contributing to peer-reviewed publications that explore cancer biomarkers, tumour microenvironment, immunohistochemistry (IHC), immunofluorescence (IF), and tissue microarray (TMA) techniques. Her work often bridges the gap between clinical diagnostics and translational research, with a special interest in the application of advanced staining methods and molecular profiling to improve diagnostic accuracy and prognostic evaluation.
In recent years, she has developed a growing interest in digital pathology, especially in its potential application for cancer biomarker analysis and image-based diagnostic support, aligning with current trends in precision medicine. Her contributions reflect a strong commitment to advancing cancer research through innovative yet practical laboratory approaches.
mohd fikri mustapa, raja zahratul azma raja sabudin, qhasmira abu hazir, alia suzana asri, lailatul hadziyah mohd pauzy, c-kai loh. (2025). acute megakaryoblastic leukemia with tetrasomy 21 clone in a child with down syndrome. - 22nd annual scientific meeting malaysian society of haematology 2025. .
nur aisyah shaiful azman, azma rz, alia suzana asri, qhasmira abu hazir, raja muhammad zul hatta, noorhana sofia, ahmad nasirudin mustafa, nizmah mahani, noraesah m, norafiza mohd yassin, ezalia esa. (2025). molecular characterization of alpha thalassemia among sabah populations. - 22nd annual scientific meeting malaysian society of haematology 2025. .
raja zahratul azma raja sabudin. (2025). molecular heterogeneity of g6pd deficiency in malaysia population. - 22nd annual scientific meeting malaysian society of haematology 2025. .
ummul afila omar, suria hayati binti md pauzi, mohd razif bin mohamad yunus, rosnah sutan, nur maya sabrina binti tizen laim, muaatamarulain bin mustangin and reena rahayu md zin. (2025). evaluation of ck8/18 and ck19 expression as adjunct immunohistochemical markers in non-keratinizing nasopharyngeal carcinoma. - diagnostics. 1 - 12.
geok chin tan, yin ping wong, soon keng cheong. (2025). ai-generated scientific papers: is it acceptable?. - the malaysian journal of pathology. 209 - 209.
ummul afila omar, suria hayati binti md pauzi, mohd razif bin mohamad yunus, rosnah sutan, nur maya sabrina binti tizen laim, muaatamarulain bin mustangin and reena rahayu md zin. (2025). evaluation of ck8/18 and ck19 expression as adjunct immunohistochemical markers in non-keratinizing nasopharyngeal carcinoma. - diagnostics. 1 - 12.
nurkhairul bariyah baharun, mohamed afiq hidayat zailani, afzan adam, qiaoyi xu, muaatamarulain mustangin, reena rahayu md zin. (2025). assessment of tumor-infiltrating lymphocytes in triple-negative breast cancer: interobserver variability and contributing factors. - diagnostics. 1 - 17.
nurkhairul bariyah baharun, afzan adam, mohamed afiq hidayat zailani, nasir m. rajpoot, qiaoyi xu and reena rahayu md zin. (2024). automated scoring methods for quantitative interpretation of tumour infiltrating lymphocytes (tils) in breast cancer: a systematic review. - bmc cancer. 1 - 19.
hashim halim-fikri, ninie nadia zulkipli, hafiza alauddin, celeste bento, carsten w lederer5, petros kountouris, marina kleanthous, yetti hernaningsih, meow-keong thong, muhammad hamdi mahmood, norafiza mohd yasin, ezalia esa, jacques elion, domenico coviello, raja-zahratul-azma raja-sabudin, ghada el-kamah, john burn, narazah mohd yusoff, raj ramesar, bin alwi zilfalil, on behalf of the global globin network (ggn). (2024). global globin network and adopting genomic variant database requirements for thalassemia. - database-the journal of biological databases and curation. 1 - 14.
pathmanathan rajadurai, sarala ravindran, bang rom lee, suria hayati md pauzi, seow fan chiew, kean hooi teoh, navarasi s. raja gopal, mastura md yusof, cheng har yip. (2024). consensus guidelines on human epidermal growth factor receptor 2 (her2)-low testing in breast cancer in malaysia. - cancers. 1 - 19.
geok chin tan, yin ping wong, soon keng cheong. (2025). ai-generated scientific papers: is it acceptable?. - the malaysian journal of pathology. 209 - 209.
wei meng phang, jonathan wei de tan, eng hong goh, li lian goh, yin ping wong, geok chin tan. (2025). a case of large renal angiomyolipoma resulted in hydronephrosis. - malaysian journal of pathology. 315 - 318.
farah azima abdul muttlib, raja zahratul azma raja sabudin, maizatul-husna mohamed ramli, norunaluwar jalil, norafiza mohd yasin, shahzuwan hassan, faidatul-syazlin abdul hassan, hafiza alauddin and ainoon othman . (2025). multiplex ligation-dependent probe amplification (mlpa) assay: a single centre experience of mlpa assay for alpha thalassaemia diagnosis. - the malaysian journal of pathology. 287 - 295.
ramlah mohamed ibrahim, raja zahratul azma raja sabudin, noor aini anuwar, azlin ithnin, mohd fikri mustapa, sivakumar palaniapan, nor rafeah tumian. (2024). bone marrow fibrosis in a young patient with chronic myeloid leukaemia . - malaysian journal of pathology. 470 - 470.
izzatul aliaa badaruddin, hanita othman, wan muhammad azfar wan shuaib, mohd zakie che yusof, shahifaniza othman, mohd nazrul anuar ali, ida mastura mat, munirah md mansor, azmawati mohammed nawi. (2024). navigating immune landscapes: insights from a prospective study. - asia pacific journal of public health. 806 - 809.
ummul afila omar, suria hayati binti md pauzi, mohd razif bin mohamad yunus, rosnah sutan, nur maya sabrina binti tizen laim, muaatamarulain bin mustangin and reena rahayu md zin. (2025). evaluation of ck8/18 and ck19 expression as adjunct immunohistochemical markers in non-keratinizing nasopharyngeal carcinoma. - diagnostics. 1 - 12.
geok chin tan, yin ping wong, soon keng cheong. (2025). ai-generated scientific papers: is it acceptable?. - the malaysian journal of pathology. 209 - 209.
wei meng phang, jonathan wei de tan, eng hong goh, li lian goh, yin ping wong, geok chin tan. (2025). a case of large renal angiomyolipoma resulted in hydronephrosis. - malaysian journal of pathology. 315 - 318.
farah azima abdul muttlib, raja zahratul azma raja sabudin, maizatul-husna mohamed ramli, norunaluwar jalil, norafiza mohd yasin, shahzuwan hassan, faidatul-syazlin abdul hassan, hafiza alauddin and ainoon othman . (2025). multiplex ligation-dependent probe amplification (mlpa) assay: a single centre experience of mlpa assay for alpha thalassaemia diagnosis. - the malaysian journal of pathology. 287 - 295.
nurkhairul bariyah baharun, mohamed afiq hidayat zailani, afzan adam, qiaoyi xu, muaatamarulain mustangin, reena rahayu md zin. (2025). assessment of tumor-infiltrating lymphocytes in triple-negative breast cancer: interobserver variability and contributing factors. - diagnostics. 1 - 17.
mohamed afiq hidayat zailani, reena rahayu md zin, raja zahratul azma raja sabudin, nurwahyuna rosli, nur maya sabrina tizen laim, muhammad dinie afif jamaludin, rohaina che man, muhammad ziqrill mohd zapri, muaatamarulain mustangin, tengku siti meriam tengku wook, helmi norman. (2025). upholding credibility and education quality in the digital era: a narrative review on ai-driven virtual pathology museums. - medicine & health. 1 - 84.
nur maya sabrina tizen laim. (2022). teknik aturan mikro tisu. - . 1-19.
nurwahyuna rosli, nur maya sabrina tizen laim. (2021). apa yang doktor buat dengan apendiks saya? - perjalanan tisu dari meja pembedahan ke pentas mikroskop. - majalah patologi. 1-6.
husyairi harunarashid, nurul saadah ahmad, nur maya sabrina tizen laim, nurazilah mohamed sallehulldin. (2021). menggembeling kekuatan bakat saintifik dan penyelidikan melalui pemerkasaan deskripsi tugas skim q (ro) di makmal,pusat kecemerlangan dan hospital pengajar milik institusi pengajian tinggi awam. - . 1-18.
tan geok chin, nur maya sabrina tizen laim. (2018). mikrorna dan isomirs: kecil tetapi berperanan besar. - majalah patologi. .
geok chin tan, sabrina florence chandramaya. (2017). plasenta: teman si bayi. - majalah patologi. 1-3.
nurkhairul bariyah baharun, mohamed afiq hidayat zailani, afzan adam, reena rahayu md zin, nasir m. rajpoot, qiaoyi xu, muaatamarulain mustangin. (2025). can artificial intelligence replace pathologists in tumour infiltrating lymphocyte (til) assessment? a comparative study of manual versus ai-based scoring in triple-negative breast cancer (tnbc). - international congress of pathology and laboratory medicine (icpalm) 2025. .
wei meng phang, eng hong goh, yin ping wong, geok chin tan. (2025). a large renal angiomyolipoma causing hydronephrosis. - international congress of pathology and laboratory medicine (icpalm) 2025. .
mohamed afiq hidayat zailani, reena rahayu md zin, raja zahratul azma raja sabudin, nurwahyuna rosli, nur maya sabrina tizen laim, muhammad dinie afif jamaludin, rohaina che man, muhammad ziqrill mohd zapri, muaatamarulain mustangin, tengku siti meriam tengku wook, helmi norman. (2025). upholding credibility and education quality in the digital era: a narrative review on ai-driven virtual pathology museums. - 27th medical and health research week 2025. .
thian qin zhang, reena rahayu md zin, muaatamarulain mustangin, nur maya sabrina tizen laim, nur fa’izah ab muin, nurwahyuna rosli. (2025). pd-l1 expression, mismatch-repair status and tumour-infiltrating lymphocytes in triple-negative breast carcinoma. - 10th iapmd annual scientific meeting 2025. .
wei meng phang , muaatamarulain mustangin , nur maya sabrina tizen , shamsul azhar shah , yin ping wong , geok chin tan. (2025). expression of lrrc15 in the placenta of pregnancies complicated with preeclampsia and fetal growth restriction. - international congress of pathology and laboratory medicine (icpalm) 2025. .
PATHOLOGY :CLINICAL AND HEALTH SCIENCES
LABORATORY MEDICINE, HISTOLOGY, HISTOPATHOLOGY, MOLECULAR GENETICS
Pengalaman / Experience : 12 tahun/years(s)