My research focuses on clinical pharmacology, pharmacometrics, and evidence synthesis in pharmacotherapy. The overarching aim is to improve dose individualisation and make drug therapy safer and more effective. I work across both experimental and computational approaches — developing bioanalytical assays with HPLC and applying modelling and simulation to explore pharmacokinetics and pharmacodynamics. I use tools such as MATLAB, R, NONMEM, and Monolix in my work.
Much of my current research looks at anticoagulants, immunoglobulin G, oncology, and vitamin D. I’ve also published more than 15 systematic reviews and meta-analyses in pharmacotherapy, reflecting my interest in using evidence synthesis to guide practice.
Beyond academia, I continue to practice as a community pharmacist, which helps me bridge research and teaching with everyday clinical realities.
nor asyikin binti mohd tahir ,mohd bin makmor bakry ,aliza binti mohamad yusof ,ruslinda binti mustafar ,shamin bin mohd saffian ,muhammad nordin bin m. saud . (2026). evaluating the target attainment frequency of piperacillin and meropenem trough concentrations among the critically ill patients on continuous renal replacement therapy.. - . .
nor asyikin binti mohd tahir ,mohd bin makmor bakry ,aliza binti mohamad yusof ,ruslinda binti mustafar ,shamin bin mohd saffian ,muhammad nordin bin m. saud . (2026). evaluating the target attainment frequency of piperacillin and meropenem trough concentrations among the critically ill patients on continuous renal replacement therapy.. - . .
nor asyikin binti mohd tahir ,mohd bin makmor bakry ,aliza binti mohamad yusof ,ruslinda binti mustafar ,shamin bin mohd saffian ,muhammad nordin bin m. saud . (2026). evaluating the target attainment frequency of piperacillin and meropenem trough concentrations among the critically ill patients on continuous renal replacement therapy.. - . .
nor asyikin binti mohd tahir ,mohd bin makmor bakry ,aliza binti mohamad yusof ,ruslinda binti mustafar ,shamin bin mohd saffian ,muhammad nordin bin m. saud . (2026). evaluating the target attainment frequency of piperacillin and meropenem trough concentrations among the critically ill patients on continuous renal replacement therapy.. - . .
azim haikal md roslan, tengku marsya hadaina tengku muhazan shah, shamin mohd saffian, lisha jenny john, muhammad danial che ramli, che mohd nasril che mohd nassir, mohd kaisan mahadi, zaw myo hein. (2026). neuroprotective potential of sglt2 inhibitors in animal models of alzheimer’s disease and type 2 diabetes mellitus: a systematic review. - pharmaceuticals. 1 - 18.
azim haikal md roslan, tengku marsya hadaina tengku muhazan shah, shamin mohd saffian, lisha jenny john, muhammad danial che ramli, che mohd nasril che mohd nassir, mohd kaisan mahadi, zaw myo hein. (2026). neuroprotective potential of sglt2 inhibitors in animal models of alzheimer’s disease and type 2 diabetes mellitus: a systematic review. - pharmaceuticals. 1 - 18.
christian andrew almalbis, adyani md redzuan, chester paul andrada, nicole ann gonzaga, shamin mohd saffian. (2025). peak and trough concentrations of apixaban and rivaroxaban in adult patients: a systematic review and meta-analysis. - journal of thrombosis and haemostasis. 1289 - 1314.
christian andrew almalbis, adyani md redzuan, shamin mohd saffian. (2025). bleeding risk prediction in non-valvular atrial fibrillation: comparing risk scores in apixaban and rivaroxaban-treated patients. - clinical and applied thrombosis-hemostasis. 1 - 10.
nazatul adhwa mohd rozi, nor asyikin mohd tahir, shamin mohd saffian, mohd makmor-bakry, aliza mohamad yusof, ruslinda mustafar, muhammad nordin m saud . (2024). therapeutic drug monitoring-guided piperacillin dosing in critically ill patients undergoing continuous renal replacement therapy: a systematic review. - journal of antimicrobial chemotherapy. 3078 - 3090.
yan qi tan, c-khai loh, shamin mohd saffian, suzana makpol. (2024). improved hplc method with automated pre-column sample derivatisation for serum pegylated l-asparaginase activity measurement in paediatric acute lymphoblastic leukaemia patients. - journal of pharmaceutical and biomedical analysis. 1-9.
jian lynn lee, noraida mohamed shah, mohd makmor-bakry, farida islahudin, hamidah alias, shamin mohd saffian. (2024). population pharmacokinetic model of intravenous immunoglobulin in patients treated for various immune system disorders. - clinical therapeutics. 25 - 37.
farah aida a. zairol azwan, yi ying teo, nor asyikin mohd tahir, shamin mohd saffian, mohd makmor-bakry, mohd shahrir mohamed said. (2024). a systematic review of single nucleotide polymorphisms affecting allopurinol pharmacokinetics and serum uric acid level . - pharmacogenomics. 479 - 494.
hock peng koh, adyani md redzuan, shamin mohd saffian, jivanraj r. nagarajah, noel thomas ross, hasnita hassan. (2022). the outcomes of reperfusion therapy with streptokinase versus tenecteplase in st-elevation myocardial infarction (stemi): a propensity-matched retrospective analysis in an asian population. - international journal of clinical pharmacy. 641-650.
z zainal abidin, za zainuren, e noor, ns mohd nor, s mohd saffian, r abdul halim. (2021). periodontal health status of children and adolescents with diabetes mellitus: a systematic review and meta-analysis. - australian dental journal. S15-S26.
nor asyikin mohd tahir, shamin mohd saffian, farida hanim islahudin, abdul halim abdul gafor, hanita othman, hamizah abdul manan, mohd makmor-bakry. (2020). effects of cst3 gene g73a polymorphism on cystatin c in a prospective multiethnic cohort study. - nephron. 204-212.
azim haikal md roslan, tengku marsya hadaina tengku muhazan shah, shamin mohd saffian, lisha jenny john, muhammad danial che ramli, che mohd nasril che mohd nassir, mohd kaisan mahadi, zaw myo hein. (2026). neuroprotective potential of sglt2 inhibitors in animal models of alzheimer’s disease and type 2 diabetes mellitus: a systematic review. - pharmaceuticals. 1 - 18.
christian andrew almalbis, adyani md redzuan, shamin mohd saffian. (2025). bleeding risk prediction in non-valvular atrial fibrillation: comparing risk scores in apixaban and rivaroxaban-treated patients. - clinical and applied thrombosis-hemostasis. 1 - 10.
christian andrew almalbis, adyani md redzuan, chester paul andrada, nicole ann gonzaga, shamin mohd saffian. (2025). peak and trough concentrations of apixaban and rivaroxaban in adult patients: a systematic review and meta-analysis. - journal of thrombosis and haemostasis. 1289 - 1314.
nur fatin najwa azemia, farida islahudin, rahela ambaras khan, shamin mohd saffian, leong chee loon. (2024). methylprednisolone use in hospitalised covid-19 patients: a retrospective study. - journal of pharmaceutical policy and practice. 2337125 - 2337125.
farah aida a. zairol azwan, yi ying teo, nor asyikin mohd tahir, shamin mohd saffian, mohd makmor-bakry, mohd shahrir mohamed said. (2024). a systematic review of single nucleotide polymorphisms affecting allopurinol pharmacokinetics and serum uric acid level . - pharmacogenomics. 479 - 494.
adyani md redzuan, shamin mohd saffian, salmi abdul razak. (2023). klinik kepatuhan ubat rheumatologi. - . 58 - 70.
mohd makmor bakry, ernieda md hatah, noraida mohamed shah. (2020). definisi dan perkembangan terma kepatuhan. - . 19 - 24.
adyani md redzuan, shamin mohd saffian, salmi abdul razak. (2023). klinik kepatuhan ubat rheumatologi. - . 58 - 70.
mohd makmor bakry, ernieda md hatah, noraida mohamed shah. (2020). definisi dan perkembangan terma kepatuhan. - . 19 - 24.
nor asyikin binti mohd tahir ,mohd bin makmor bakry ,aliza binti mohamad yusof ,ruslinda binti mustafar ,shamin bin mohd saffian ,muhammad nordin bin m. saud . (2026). evaluating the target attainment frequency of piperacillin and meropenem trough concentrations among the critically ill patients on continuous renal replacement therapy.. - . .
nor asyikin binti mohd tahir ,mohd bin makmor bakry ,aliza binti mohamad yusof ,ruslinda binti mustafar ,shamin bin mohd saffian ,muhammad nordin bin m. saud . (2026). evaluating the target attainment frequency of piperacillin and meropenem trough concentrations among the critically ill patients on continuous renal replacement therapy.. - . .
nor asyikin binti mohd tahir ,mohd bin makmor bakry ,aliza binti mohamad yusof ,ruslinda binti mustafar ,shamin bin mohd saffian ,muhammad nordin bin m. saud . (2026). evaluating the target attainment frequency of piperacillin and meropenem trough concentrations among the critically ill patients on continuous renal replacement therapy.. - . .
nor asyikin binti mohd tahir ,mohd bin makmor bakry ,aliza binti mohamad yusof ,ruslinda binti mustafar ,shamin bin mohd saffian ,muhammad nordin bin m. saud . (2026). evaluating the target attainment frequency of piperacillin and meropenem trough concentrations among the critically ill patients on continuous renal replacement therapy.. - . .
lim jia hui, nazatul adhwa mohd rozi, shamin saffian, mohd makmor-bakry, aliza mohamad yusof, ruslinda mustafar, muhammad nordin m saud, nor asyikin mohd tahir. (2025). therapeutic drug monitoring-guided dosing of meropenem on patients receiving continuous renal replacement therapy: a systematic review. - regional asia-pacific therapeutic drug monitoring conference 2025 (raptdm2025). .
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| KESAN KETAGIHAN DAN KETOKSIKAN BAHAN PSIKOAKTIF BAHARU (NPS) TERPILIH | jabatan siasatan jenayah narkotik, polis diraja malaysia | 76.3% (2023-11-01 sehingga 2026-12-31) |
| PROFILING THE PATTERN OF USE OF NEW PSYCHOACTIVE SUBSTANCES (NPS) IN MALAYSIA | agensi antidadah kebangsaan (aadk) | 98.1% (2024-05-15 sehingga 2026-04-14) |
PHARMACY :CLINICAL AND HEALTH SCIENCES
Pharmacometrics
Pengalaman / Experience : 3 tahun/years(s)