dr. shamin bin mohd saffian

pensyarah farmasi duf51

pejabat dekan fakulti farmasi

 shamin@ukm.edu.my

No. Telefon Rasmi :  0392897960

No. rasmi:
UKM : 03 8921 5555



   Biografi/ Biography :

  • I graduated with a BPharm (Univ of Otago, NZ) in 2009. I then practiced as a pharmacist under the Ministry of Health, Malaysia for 3 years. In 2013, I completed my Postgraduate Certificate in Pharmacy, and subsequently a PhD in 2018 (both at Univ of Otago). My PhD thesis is in the area of in clinical pharmacology and pharmacometrics of oral anticoagulants. In 2018, I was appointed senior lecturer. My current research focuses on clinical pharmacology and pharmacometrics. Pharmacometrics is the science of mathematical and statistical methods to quantify the interaction between xenobiotics and biological response (pharmacokinetics/dynamics, disease progression, time course of drug response etc). One main application of this is in dose individualisation. Hence, my research involves developing bioanalytical drug assay using LCMS/MS and HPLC, computational modelling and simulation of pharmacokinetics and pharmacometrics models. Softwares that are used include MATLAB, R, NONMEM and Monolix. I have in-depth interest in assembling scientific evidence as the basis for improving treatment. He has been involved in many evidence-based pharmacotherapy research using different techniques (systematic reviews of clinical and pre-clinical studies, meta-analyses, and meta-regression). Currently, I am also a practicing community pharmacist.

  • jose de leon, georgios schoretsanitis, robert l. smith, espen molden, anssi solismaa, niko seppala, miloslav kopecek, patrik svancer, ismael olmos, carina ricciardi, celso iglesias-garcia, ana iglesias-alonso, edoardo spina, shamin mohd saffian et al..  (2022).  correction: an international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, crp, and clozapine levels.  - pharmacopsychiatry.  e1. 

     

    hock peng koh, adyani md redzuan, shamin mohd saffian, jivanraj r. nagarajah, noel thomas ross, hasnita hassan.  (2022).  the outcomes of reperfusion therapy with streptokinase versus tenecteplase in st-elevation myocardial infarction (stemi): a propensity-matched retrospective analysis in an asian population.  - international journal of clinical pharmacy.  641-650. 

     

    fei yee lee, farida islahudin, abdul halim abdul gafor, hin-seng wong, sunita bavanandan, shamin mohd saffian, adyani md redzuan, mohd makmor-bakry.  (2022).  adverse drug reactions of antihypertensives and cyp3a5*3 polymorphism among chronic kidney disease patients.  - frontiers in pharmacology.  1-8. 

     

    jose de leon, georgios schoretsanitis, robert l. smith, espen molden, anssi solismaa, niko seppala, miloslav kopecek, patrik svancer, ismael olmos, carina ricciardi, celso iglesias-garcia, ana iglesias-alonso, edoardo spina, shamin mohd saffian et al..  (2022).  an international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, crp, and clozapine levels.  - pharmacopsychiatry.  73-86. 

     

    sareneya dashni rajahthurai, muhammad junaid farrukh, mohd makmor-bakry, hui jan tan, omotayo fatokun, shamin mohd saffian and diana laila ramatillah.  (2022).  use of complementary and alternative medicine and adherence to medication therapy among stroke patients: a meta-analysis and systematic review.  - frontiers in pharmacology.  1-15. 

     

    hock peng koh, adyani md redzuan, shamin mohd saffian, jivanraj r. nagarajah, noel thomas ross, hasnita hassan.  (2022).  clinical profile and predictors of 30-day all-cause mortality of stelevation myocardial infarction (stemi) patients receiving fibrinolytic therapy in an asian population.  - heart & lung.  68-76. 

     

    jose de leon, georgios schoretsanitis, robert l. smith, espen molden, anssi solismaa, niko seppala, miloslav kopecek, patrik svancer, ismael olmos, carina ricciardi, celso iglesias-garcia, ana iglesias-alonso, edoardo spina, shamin mohd saffian et al..  (2022).  correction: an international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, crp, and clozapine levels.  - pharmacopsychiatry.  e1. 

     

    jian lynn lee, shamin mohd saffian, mohd makmor-bakry, farida islahudin, hamidah alias, adli ali, noraida mohamed shah.  (2022).  prescribing practices of intravenous immunoglobulin in tertiary care hospitals in malaysia: a need for a national guideline for immunoglobulin use.  - frontiers in pharmacology.  1-11. 

     

    shamin mohd saffian, jian lynn lee, makmor-bakry mohd, farida islahudin, noraida mohamed shah.  (2022).  population pharmacokinetic modeling of intravenous immunoglobulin in patients with immune system disorders.  - cpt: pharmacometrics & systems pharmacology.  S13. 

     

    hock peng koh, adyani md redzuan, shamin mohd saffian, jivanraj nagarajah, noel thomas ross, hasnita hassan.  (2022).  impact of covid-19 pandemic on stemi thrombolysis and emergency department's performance in a non-pci capable tertiary hospital.  - american journal of emergency medicine.  9-14. 

     

    hock peng koh, adyani md redzuan, shamin mohd saffian, jivanraj r. nagarajah, noel thomas ross, hasnita hassan.  (2022).  the outcomes of reperfusion therapy with streptokinase versus tenecteplase in st-elevation myocardial infarction (stemi): a propensity-matched retrospective analysis in an asian population.  - international journal of clinical pharmacy.  641-650. 

     

    z zainal abidin, za zainuren, e noor, ns mohd nor, s mohd saffian, r abdul halim.  (2021).  periodontal health status of children and adolescents with diabetes mellitus: a systematic review and meta-analysis.  - australian dental journal.  S15-S26. 

     

    nor asyikin mohd tahir, shamin mohd saffian, farida hanim islahudin, abdul halim abdul gafor, hanita othman, hamizah abdul manan, mohd makmor-bakry.  (2020).  effects of cst3 gene g73a polymorphism on cystatin c in a prospective multiethnic cohort study.  - nephron.  204-212. 

     

    nor asyikin mohd tahir, abdul halim abdul gafor, farida hanim islahudin, shamin mohd saffian, hamizah abdul manan, hanita othman, mohd makmor-bakry.  (2018).  agreement between creatinine and cystatin c-based equations in the estimation of glomerular filtration rate among malaysian patients with renal impairment.  - indian journal of pharmaceutical education and research. 

     

    jose de leon, georgios schoretsanitis, robert l. smith, espen molden, anssi solismaa, niko seppala, miloslav kopecek, patrik svancer, ismael olmos, carina ricciardi, celso iglesias-garcia, ana iglesias-alonso, edoardo spina, shamin mohd saffian et al..  (2022).  correction: an international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, crp, and clozapine levels.  - pharmacopsychiatry.  e1. 

     

    hock peng koh, adyani md redzuan, shamin mohd saffian, jivanraj r. nagarajah, noel thomas ross, hasnita hassan.  (2022).  the outcomes of reperfusion therapy with streptokinase versus tenecteplase in st-elevation myocardial infarction (stemi): a propensity-matched retrospective analysis in an asian population.  - international journal of clinical pharmacy.  641-650. 

     

    fei yee lee, farida islahudin, abdul halim abdul gafor, hin-seng wong, sunita bavanandan, shamin mohd saffian, adyani md redzuan, mohd makmor-bakry.  (2022).  adverse drug reactions of antihypertensives and cyp3a5*3 polymorphism among chronic kidney disease patients.  - frontiers in pharmacology.  1-8. 

     

    sareneya dashni rajahthurai, muhammad junaid farrukh, mohd makmor-bakry, hui jan tan, omotayo fatokun, shamin mohd saffian and diana laila ramatillah.  (2022).  use of complementary and alternative medicine and adherence to medication therapy among stroke patients: a meta-analysis and systematic review.  - frontiers in pharmacology.  1-15. 

     

    jose de leon, georgios schoretsanitis, robert l. smith, espen molden, anssi solismaa, niko seppala, miloslav kopecek, patrik svancer, ismael olmos, carina ricciardi, celso iglesias-garcia, ana iglesias-alonso, edoardo spina, shamin mohd saffian et al..  (2022).  an international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, crp, and clozapine levels.  - pharmacopsychiatry.  73-86. 

     

    noraida mohamed shah, jian lynn, lee, shamin mohd saffian, farida islahudin, mohd makmor bakry, hamidah alias.  (2022).  off-labelled uses of intravenous immunoglobulin g at two tertiary hospitals in malaysia.  - 10th asian association of schools of pharmacy (aasp) conference.  1-5. 

     

    z. zainal abidin , z.a zainuren, e. noor, n.s mohd nor, s. mohd saffian, r. abdul halim.  (2021).  periodontal health status of children and adolescents with diabetes mellitus: a systematic review and meta-analysis.  - malaysian association of paediatric dentistry (mapd) 2021.  12. 

     

    adyani md redzuan, hock peng koh, shamin mohd saffian, jivanraj r. nagarajah, noel thomas ross, hasnita hassan.  (2021).  the outcomes of streptokinase versus tenecteplase in st-elevation myocardial infarction (stemi): a propensity-matched retrospective analysis in a multiracial asian country.  - 3rd international conference of pharmacy and health sciences 2021 (icphs 2021).  155. 

     

    ng jia wei, shamin mohd saffian, nor asyikin mohd tahir.  (2021).  safety, efficacy and variability of dabigatran therapy.  - pharmacy research day 2021.  64. 

     

    noraida mohamed shah, jian lynn lee, shamin mohd saffian, farida h. islahudin, mohd makmor-bakry, hamidah alias, lokman m. noh, intan hakimah ismail.  (2020).  population pharmacokinetics of intravenous immunoglobulin g in patients with primary immunodeficiency in malaysia.  - european society for paediatric infectious diseases (espid 2020).  -.