Kluster Kepakaran/ Cluster of Expertise :
Biografi/ Biography :
My research focuses on clinical pharmacology, pharmacometrics, and evidence synthesis in pharmacotherapy. The overarching aim is to improve dose individualisation and make drug therapy safer and more effective. I work across both experimental and computational approaches — developing bioanalytical assays with HPLC and applying modelling and simulation to explore pharmacokinetics and pharmacodynamics. I use tools such as MATLAB, R, NONMEM, and Monolix in my work.
Much of my current research looks at anticoagulants, immunoglobulin G, oncology, and vitamin D. I’ve also published more than 15 systematic reviews and meta-analyses in pharmacotherapy, reflecting my interest in using evidence synthesis to guide practice.
Beyond academia, I continue to practice as a community pharmacist, which helps me bridge research and teaching with everyday clinical realities.
christian andrew almalbis, adyani md redzuan, chester paul andrada, nicole ann gonzaga, shamin mohd saffian. (2025). peak and trough concentrations of apixaban and rivaroxaban in adult patients: a systematic review and meta-analysis. - journal of thrombosis and haemostasis. 1289 - 1314.
christian andrew almalbis, adyani md redzuan, shamin mohd saffian. (2025). bleeding risk prediction in non-valvular atrial fibrillation: comparing risk scores in apixaban and rivaroxaban-treated patients. - clinical and applied thrombosis-hemostasis. 1 - 10.
lim jia hui, nazatul adhwa mohd rozi, shamin saffian, mohd makmor-bakry, aliza mohamad yusof, ruslinda mustafar, muhammad nordin m saud, nor asyikin mohd tahir. (2025). therapeutic drug monitoring-guided dosing of meropenem on patients receiving continuous renal replacement therapy: a systematic review. - regional asia-pacific therapeutic drug monitoring conference 2025 (raptdm2025). .
farah aida a. zairol azwan, shamin mohd saffian, mohd makmor-bakry, mohd shahrir mohamed said, nor asyikin mohd tahir. (2025). the influence of abcg2 rs2231142 and haox1 rs3731722 polymorphisms on oxypurinol concentration in gout patients. - regional asia-pacific therapeutic drug monitoring conference 2025 (raptdm2025). .
farah aida a. zairol azwan, shamin mohd saffian, mohd makmor-bakry, mohd shahrir mohamed said, nor asyikin mohd tahir. (2025). population pharmacokinetic of oxypurinol in adult patients: a systematic review. - regional asia-pacific therapeutic drug monitoring conference 2025 (raptdm2025). .
christian andrew almalbis, adyani md redzuan, chester paul andrada, nicole ann gonzaga, shamin mohd saffian. (2025). peak and trough concentrations of apixaban and rivaroxaban in adult patients: a systematic review and meta-analysis. - journal of thrombosis and haemostasis. 1289 - 1314.
christian andrew almalbis, adyani md redzuan, shamin mohd saffian. (2025). bleeding risk prediction in non-valvular atrial fibrillation: comparing risk scores in apixaban and rivaroxaban-treated patients. - clinical and applied thrombosis-hemostasis. 1 - 10.
yan qi tan, c-khai loh, shamin mohd saffian, suzana makpol. (2024). improved hplc method with automated pre-column sample derivatisation for serum pegylated l-asparaginase activity measurement in paediatric acute lymphoblastic leukaemia patients. - journal of pharmaceutical and biomedical analysis. 1-9.
nazatul adhwa mohd rozi, nor asyikin mohd tahir, shamin mohd saffian, mohd makmor-bakry, aliza mohamad yusof, ruslinda mustafar, muhammad nordin m saud . (2024). therapeutic drug monitoring-guided piperacillin dosing in critically ill patients undergoing continuous renal replacement therapy: a systematic review. - journal of antimicrobial chemotherapy. 3078 - 3090.
hock peng koh, adyani md redzuan, shamin mohd saffian, hasnita hassan, jivanraj r. nagarajah, noel thomas ross. (2023). mortality outcomes and predictors of failed thrombolysis following stemi thrombolysis in a non-pci capable tertiary hospital: a 5-year analysis. - internal and emergency medicine. 1169-1180.
farah aida a. zairol azwan, yi ying teo, nor asyikin mohd tahir, shamin mohd saffian, mohd makmor-bakry, mohd shahrir mohamed said. (2024). a systematic review of single nucleotide polymorphisms affecting allopurinol pharmacokinetics and serum uric acid level . - pharmacogenomics. 479 - 494.
jian lynn lee, noraida mohamed shah, mohd makmor-bakry, farida islahudin, hamidah alias, shamin mohd saffian. (2024). population pharmacokinetic model of intravenous immunoglobulin in patients treated for various immune system disorders. - clinical therapeutics. 25 - 37.
hock peng koh, adyani md redzuan, shamin mohd saffian, jivanraj r. nagarajah, noel thomas ross, hasnita hassan. (2022). the outcomes of reperfusion therapy with streptokinase versus tenecteplase in st-elevation myocardial infarction (stemi): a propensity-matched retrospective analysis in an asian population. - international journal of clinical pharmacy. 641-650.
z zainal abidin, za zainuren, e noor, ns mohd nor, s mohd saffian, r abdul halim. (2021). periodontal health status of children and adolescents with diabetes mellitus: a systematic review and meta-analysis. - australian dental journal. S15-S26.
nor asyikin mohd tahir, shamin mohd saffian, farida hanim islahudin, abdul halim abdul gafor, hanita othman, hamizah abdul manan, mohd makmor-bakry. (2020). effects of cst3 gene g73a polymorphism on cystatin c in a prospective multiethnic cohort study. - nephron. 204-212.
christian andrew almalbis, adyani md redzuan, chester paul andrada, nicole ann gonzaga, shamin mohd saffian. (2025). peak and trough concentrations of apixaban and rivaroxaban in adult patients: a systematic review and meta-analysis. - journal of thrombosis and haemostasis. 1289 - 1314.
christian andrew almalbis, adyani md redzuan, shamin mohd saffian. (2025). bleeding risk prediction in non-valvular atrial fibrillation: comparing risk scores in apixaban and rivaroxaban-treated patients. - clinical and applied thrombosis-hemostasis. 1 - 10.
nazatul adhwa mohd rozi, nor asyikin mohd tahir, shamin mohd saffian, mohd makmor-bakry, aliza mohamad yusof, ruslinda mustafar, muhammad nordin m saud . (2024). therapeutic drug monitoring-guided piperacillin dosing in critically ill patients undergoing continuous renal replacement therapy: a systematic review. - journal of antimicrobial chemotherapy. 3078 - 3090.
jian lynn lee, noraida mohamed shah, mohd makmor-bakry, farida islahudin, hamidah alias, shamin mohd saffian. (2024). population pharmacokinetic model of intravenous immunoglobulin in patients treated for various immune system disorders. - clinical therapeutics. 25 - 37.
nur fatin najwa azemia, farida islahudin, rahela ambaras khan, shamin mohd saffian, leong chee loon. (2024). methylprednisolone use in hospitalised covid-19 patients: a retrospective study. - journal of pharmaceutical policy and practice. 2337125 - 2337125.
lim jia hui, nazatul adhwa mohd rozi, shamin saffian, mohd makmor-bakry, aliza mohamad yusof, ruslinda mustafar, muhammad nordin m saud, nor asyikin mohd tahir. (2025). therapeutic drug monitoring-guided dosing of meropenem on patients receiving continuous renal replacement therapy: a systematic review. - regional asia-pacific therapeutic drug monitoring conference 2025 (raptdm2025). .
farah aida a. zairol azwan, shamin mohd saffian, mohd makmor-bakry, mohd shahrir mohamed said, nor asyikin mohd tahir. (2025). the influence of abcg2 rs2231142 and haox1 rs3731722 polymorphisms on oxypurinol concentration in gout patients. - regional asia-pacific therapeutic drug monitoring conference 2025 (raptdm2025). .
farah aida a. zairol azwan, shamin mohd saffian, mohd makmor-bakry, mohd shahrir mohamed said, nor asyikin mohd tahir. (2025). population pharmacokinetic of oxypurinol in adult patients: a systematic review. - regional asia-pacific therapeutic drug monitoring conference 2025 (raptdm2025). .
iman zaki, adli ali, sharifah azween omar, wong sau wei, nor asyikin mohd tahir, shamin saffian, a’dina rizal, nurazwa rizal. (2024). awareness of and attitudes toward pharmacogenetic testing for hla-b*15:02 among parents/guardians of epileptic patients in malaysia: a qualitative study. - 26th medical & health research week. .
teo yi ying, farah aida a. zairol azwan, shamin saffian, mohd makmor-bakry, mohd shahrir mohamed said, nor asyikin mohd tahir.. (2024). effects of single nucleotide polymorphism (snp) in pharmacokinetic (pk) of allopurinol and oxypurinol: a scoping review. - 2nd pharmcare symposium. .
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| KESAN KETAGIHAN DAN KETOKSIKAN BAHAN PSIKOAKTIF BAHARU (NPS) TERPILIH | jabatan siasatan jenayah narkotik, polis diraja malaysia | 64.3% (2023-11-01 sehingga 2026-12-31) |
| PROFILING THE PATTERN OF USE OF NEW PSYCHOACTIVE SUBSTANCES (NPS) IN MALAYSIA | agensi anti dadah kebangsaan | 78.3% (2024-05-15 sehingga 2026-04-14) |
PHARMACY :CLINICAL AND HEALTH SCIENCES
Pharmacometrics
Pengalaman / Experience : 3 tahun/years(s)