pensyarah universiti
pusat kajian kejuruteraan tisu & perubatan regeneratif
dain@ukm.edu.my
No. Telefon Rasmi : 0391456995
No. rasmi:
UKM : 03 8921 5555
Knowledge on signalling molecules and the expression trend of numerous molecular regulators that elicit appropriate responses in cellular events including cytoskeletal changes, cell growth and division, matrix synthesis and degradation, differentiation, cell senescence and apoptosis are crucial in maintaining cellular equilibrium. Exploring the basic principles of how cells communicate with one another and how cell signalling pathways are subverted in pathophysiology of diseases is paramount in developing novel therapeutic targets.
Scientific approaches are currently centred on elucidating the mechanism of action and consequences of specific protein expression modification that enable further manipulation for therapeutic targets. Stem cells and its derivatives (secretomics) are an enormous reservoir of signalling molecules that are fascinating to the scientific community yet not fully understood. Stem cells brought the means for personalized medicine therapeutic approach achievable.
Therefore, understanding specific signalling pathway involved in pathophysiology of diseases i.e., rare diseases (Duchenne Muscular Dystrophy and Vagina Agenesis) and non-communicable diseases (Cardiovascular and Neuro-degenerative diseases) and upon any introduction of a compound/protein/drug for treatment is imperative to ensure safety and efficacy of proposed therapeutic approach.
intan zarina zainol abidin, anis nabilah johari, muhammad dain yazid, zaidah zainal ariffin, herryawan ryadi eziwar dyari, shahrul hisham zainal ariffin. (2023). osteogenic potential and bioactive profiles of piper sarmentosum ethanolic extract-treated stem cells. - pharmaceuticals. 1-15.
nadiah binti sulaiman;ruszymah binti haji idrus;muhammad da`in bin yazid;mohamad fikeri bin ishak. (2023). investigating the effect of hydroxytyrosol in human inflamed respiratory epithelial in vitro: possible epithelial salvage for coronavirus disease 2019 (covid-19) patients with acute respiratory distress syndrome (ards). - . .
ruth n, rusydatul nabila mr, fezah othman, santhra segaran balan, azrina zainal abidin, hashim embong, soo huat teoh, azmiza syawani jasni, siti hadizah jumidil, khaled salem yaslam ba matraf, zainul amiruddin zakaria, hasnah bahari, muhammad dain yazid. (2023). elateriospermum tapos yogurt supplement in maternal obese dams during pregnancy modulates the body composition of f1 generation. - nutrients. 1-19.
muhammad dain yazid. (2023). apabila otot manusia melemah. - sinar plus (medik) dalam akhbar sinar harian. 16-17.
ubashini vijakumaran, janushaa shanmugam, jun wei heng, siti sarah azman, muhammad dain yazid, nur atiqah haizum abdullah and nadiah sulaiman. (2023). effects of hydroxytyrosol in endothelial functioning: a comprehensive review. - molecules. 1-19.
ruth n, rusydatul nabila mr, fezah othman, santhra segaran balan, azrina zainal abidin, hashim embong, soo huat teoh, azmiza syawani jasni, siti hadizah jumidil, khaled salem yaslam ba matraf, zainul amiruddin zakaria, hasnah bahari, muhammad dain yazid. (2023). elateriospermum tapos yogurt supplement in maternal obese dams during pregnancy modulates the body composition of f1 generation. - nutrients. 1-19.
ubashini vijakumaran, janushaa shanmugam, jun wei heng, siti sarah azman, muhammad dain yazid, nur atiqah haizum abdullah and nadiah sulaiman. (2023). effects of hydroxytyrosol in endothelial functioning: a comprehensive review. - molecules. 1-19.
rabiatul adawiyah razali, muhammad dain yazid, aminuddin saim, ruszymah bt hj idrus, yogeswaran lokanathan. (2023). approaches in hydroxytyrosol supplementation on epithelial - mesenchymal transition in tgfb1-induced human respiratory epithelial cells. - international journal of molecular sciences. 1-18.
intan zarina zainol abidin, anis nabilah johari, muhammad dain yazid, zaidah zainal ariffin, herryawan ryadi eziwar dyari, shahrul hisham zainal ariffin. (2023). osteogenic potential and bioactive profiles of piper sarmentosum ethanolic extract-treated stem cells. - pharmaceuticals. 1-15.
benson koh, nadiah sulaiman, mohd fauzi mh busra, law jia xian, ng min hwei, too lih yuan, abdul ghani nur azurah, mohd heikal mohd yunus, ruszymah bt hj idrus, muhammad dain yazid.. (2023). a three-dimensional xeno-free culture condition for wharton's jelly-mesenchymal stem cells: the pros and cons. - international journal of molecular sciences. 1-18.
izyan mohd idris, fazlina nordin, nur jannaim muhamad, julaina abdul jalil, fatimah diana amin nordin, rosnani mohamed, adiratna mat ripen, gee jun tye, wan safwani wan kamarul zaman, muhammad dain yazid & min hwei ng. (2023). the establishment of in-vitro human induced pluripotent stem cell-derived neurons. - sains malaysiana. 849-862.
intan zarina zainol abidin, thanaletchumi manogaran, rohaya megat abdul wahab, saiful anuar karsani, muhammad dain yazid, farinawati yazid, zaidah zainal ariffin, anis nabilah johari, shahrul hisham zainal ariffin. (2023). label-free quantitative proteomic analysis of ascorbic acid-induced differentially expressed osteoblast-related proteins in dental pulp stem cells from deciduous and permanent teeth. - current stem cell research & therapy. 417-428.
shahrul hisham zainal ariffin, thanaletchumi manogaran, rohaya megat abdul wahab, saiful anuar karsani, intan zarina zainol abidin, farinawati yazid, muhammad dain yazid, zaidah zainal ariffin. (2022). profil protein sekretom sel stem pulpa gigi manusia semasa aruhan asid askorbik. - sains malaysiana. 2173-2186.
khidhir kamil, jaya kumar, muhammad dain yazid & ruszymah binti haji idrus. (2018). olive and its phenolic compound as the promising neuroprotective agent. - sains malaysiana. .
rohaya megat abdul wahab, farah amirah mohd nasri, intan zarina zainol abidin, zaidah zainal ariffin, muhammad dain yazid, shahrul hisham zainal ariffin. (2017). kesan penyimpanan sampel air liur terhadap kualiti dna genom. - sains malaysiana. 909-915.
intan zarina zainol abidin, anis nabilah johari, muhammad dain yazid, zaidah zainal ariffin, herryawan ryadi eziwar dyari, shahrul hisham zainal ariffin. (2023). osteogenic potential and bioactive profiles of piper sarmentosum ethanolic extract-treated stem cells. - pharmaceuticals. 1-15.
izyan mohd idris, fazlina nordin, nur jannaim muhamad, julaina abdul jalil, fatimah diana amin nordin, rosnani mohamed, adiratna mat ripen, gee jun tye, wan safwani wan kamarul zaman, muhammad dain yazid & min hwei ng. (2023). the establishment of in-vitro human induced pluripotent stem cell-derived neurons. - sains malaysiana. 849-862.
ruth n, rusydatul nabila mr, fezah othman, santhra segaran balan, azrina zainal abidin, hashim embong, soo huat teoh, azmiza syawani jasni, siti hadizah jumidil, khaled salem yaslam ba matraf, zainul amiruddin zakaria, hasnah bahari, muhammad dain yazid. (2023). elateriospermum tapos yogurt supplement in maternal obese dams during pregnancy modulates the body composition of f1 generation. - nutrients. 1-19.
ubashini vijakumaran, janushaa shanmugam, jun wei heng, siti sarah azman, muhammad dain yazid, nur atiqah haizum abdullah and nadiah sulaiman. (2023). effects of hydroxytyrosol in endothelial functioning: a comprehensive review. - molecules. 1-19.
intan zarina zainol abidin, thanaletchumi manogaran, rohaya megat abdul wahab, saiful anuar karsani, muhammad dain yazid, farinawati yazid, zaidah zainal ariffin, anis nabilah johari, shahrul hisham zainal ariffin. (2023). label-free quantitative proteomic analysis of ascorbic acid-induced differentially expressed osteoblast-related proteins in dental pulp stem cells from deciduous and permanent teeth. - current stem cell research & therapy. 417-428.
shiplu roy chowdhury, yogeswaran lokanathan, law jia xian, fauzi mh busra, muhammad dain yazid, nadiah sulaiman, gargy lahiry and md enamul hoque. (2020). design and manufacturing. - . 22.
ling ling liau, qi hao looi, sue ping eng, muhammad dain yazid, nadiah sulaiman, mohd fauzi mh busra, min hwei ng, jia xian law. (2020). stem cells: from hype to hope. - . 33.
kok-yong chin, muhammad dain yazid, mohd hafidzul jasman, raynuha mahadevan & siti mariam bujang. (2022). the covid-19 pandemic : the experiences of hospital canselor tuanku muhriz (hctm). - . 16.
ling ling liau, qi hao looi, sue ping eng, muhammad dain yazid, nadiah sulaiman, mohd fauzi mh busra, min hwei ng, jia xian law. (2020). stem cells: from hype to hope. - . 33.
shiplu roy chowdhury, yogeswaran lokanathan, law jia xian, fauzi mh busra, muhammad dain yazid, nadiah sulaiman, gargy lahiry and md enamul hoque. (2020). design and manufacturing. - . 22.
yogeswaran lokanathan, alvin chan man lung, angela ng min hwei, mohd heikal mohd yunus, ruszymah hj idrus, law jia xian, muhammad dain yazid, chin kok yong, sharen aini shamsuddin, rafizul mohd yusof, rabiatul adawiyah razali, mohd asyraf. (2023). allogeneic wharton's jelly-derived mesenchymal stem cell as cell therapy: safety study in an animal model. - international conference on molecular medicine and therapeutics (icmt-2023). 1.
yogeswaran lokanathan, anam anjum, muhammad dain yazid, muhammad fauzi daud, min hwei ng, amaramalar selvi naicker, ohnmar htwe ismail, ramesh kumar athi kumar, jalilah idris. (2023). kainic acid excitotoxicity induced chemical spinal cord injury in vivo model for assessment of neuroregeneration potential of drugs. - tissue engineering and regenerative medicine international society (termis) european chapter meeting 2023. PP408.
nadiah binti sulaiman;ruszymah binti haji idrus;muhammad da`in bin yazid;mohamad fikeri bin ishak. (2023). investigating the effect of hydroxytyrosol in human inflamed respiratory epithelial in vitro: possible epithelial salvage for coronavirus disease 2019 (covid-19) patients with acute respiratory distress syndrome (ards). - . .
muhammad dain yazid. (2023). apabila otot manusia melemah. - sinar plus (medik) dalam akhbar sinar harian. 16-17.
nadiah binti sulaiman;ruszymah binti haji idrus;mohd ramzisham bin abdul rahman;hafiza binti alauddin;raja zahratul azma raja sabudin;mohd fauzi bin mh busra;muhammad da`in bin yazid. (2022). characterisation of blood outgrowth endothelial cells (boecs) for human saphenous veins (hsv) re-endothelialisation optimisation. - . .