pensyarah universiti
institut biologi molekul perubatan ukm (umbi)
syakima@ukm.edu.my
No. Telefon Rasmi : 0391459073
No. rasmi:
UKM : 03 8921 5555
Biografi/ Biography :
Dr Syakima’s research leadership was evidenced with the appointment in various important management positions in UMBI such as the Head of Quality Assurance, Team Leader for COVID-19 RT-PCR testing, Chief Technical Officer, Lead Coordinator of Cancer Biobank, Team Leader of Cancer Genomics and Visiting Fellow of Newcastle University (UK). Her expertise in cancer research has been recognized with numerous awards, including the distinguished UK-based Rutherford Strategic Link Short Term Grant Fellowship Award by Newcastle University.
Under her excellent research leadership and activities, UMBI has developed high standard research performance in recent years with Dr Syakima directly contributing to 6 IPs, 88 published articles, 51 conference papers, 2 books, and 6 book chapters. The numbers and quality of publications she published exceeded aspirational expectation of a young scientist and already meeting exceptional research performance of a senior researcher. She has a solid track record in securing competitive national and international grants. She is the PI (5 projects totalling RM510k), co-PI and co-investigator (21 projects totalling RM5.488million) for a total of 26 competitive grants totalling at an astounding RM5.998million (year 2013-2020). With 12 grants completed with publications and postgraduates as outputs, her excellent postgraduate supervision leads to 11 graduates (year 2017-2020) and currently supervising 10 postgraduates.
Her leadership and achievements in Molecular Medicine and Genomics field have led to international recognition, evidenced by an upward trajectory on citations track, leading to a total cumulative citation of 1255 and h-index of 19. The high h-index and citations clearly depicted the impact of Dr Syakima’s research and indicating her leadership and expertise by scientists worldwide.
ryia illani my, nurul-syakima am, jia-shiun k, sazuita s, muhiddin i, saiful effendi s, francis yew ft, najwa farhah my, mohd ridhwan ar, norshahidah mn, nadiah a, isa md rose, ismail sagap, luqman mazlan, rahman jamal. (2023). whole genome sequencing of malaysian colorectal cancer patients reveals specific druggable somatic mutations. - frontiers in molecular biosciences. 1-20.
nadiah abu, nurul ainaa adilah rus bakarurraini, siti nurmi nasir, muhiddin ishak, rashidah baharuddin, rahman jamal, nurul syakima ab mutalib. (2023). methylation profile of cancer testis antigens in colorectal cancer. - iranian journal of immunology. 83-91.
nadiah binti abu;a. rahman bin a. jamal;luqman bin mazlan;nurul syakima binti ab mutalib;wan fahmi bin wan mohamad nazarie. (2022). in-depth characterisation of circulating tumour cells in metastatic colorectal cancer via single cell mrna sequencing. - . .
nurul syakima binti ab mutalib;a. rahman bin a. jamal;ismail bin sagap;luqman bin mazlan;zairul azwan bin mohd azman;isa b mohamed rose. (2022). integrated methylome and transcriptome analysis of colorectal cancers through epigenome wide approach. - . .
francis yew fu tieng, learn-han lee and nurul-syakima ab mutalib. (2022). deciphering colorectal cancer immune microenvironment transcriptional landscape on single cell resolution - a role for immunotherapy. - frontiers in immunology. 1-11.
ryia illani my, nurul-syakima am, jia-shiun k, sazuita s, muhiddin i, saiful effendi s, francis yew ft, najwa farhah my, mohd ridhwan ar, norshahidah mn, nadiah a, isa md rose, ismail sagap, luqman mazlan, rahman jamal. (2023). whole genome sequencing of malaysian colorectal cancer patients reveals specific druggable somatic mutations. - frontiers in molecular biosciences. 1-20.
mohd amin azuwar, nor azlan nor muhammad, nor afiqah-aleng, nurul-syakima ab mutalib, najwa farhah md. yusof, ryia illani mohd yunos, muhiddin ishak, sazuita saidin, isa mohamed rose, ismail sagap, luqman mazlan, zairul azwan mohd azman, musalmah mazlan. (2022). tcga-my: a systematic repository for systems biology of malaysian colorectal cancer. - life. 1-14.
rashidah baharudin, nurul qistina rus bakarurraini, imilia ismail, learn-han lee, nurul syakima ab mutalib. (2022). microrna methylome signature and their functional roles in colorectal cancer diagnosis, prognosis and chemoresistance. - international journal of molecular sciences. 1-21.
rashidah baharudin, muhiddin ishak, azliana muhamad yusof, sazuita saidin, saiful effendi syafruddin, wan fahmi wan mohamad nazarie, learn-han lee, nurul-syakima ab mutalib. (2022). epigenome-wide dna methylation profiling in colorectal cancer and normal adjacent colon using infinium human methylation 450k. - diagnostics. 1-22.
francis yew fu tieng, learn-han lee and nurul-syakima ab mutalib. (2022). deciphering colorectal cancer immune microenvironment transcriptional landscape on single cell resolution - a role for immunotherapy. - frontiers in immunology. 1-11.
nadiah abu, nurul ainaa adilah rus bakarurraini, siti nurmi nasir, muhiddin ishak, rashidah baharuddin, rahman jamal, nurul syakima ab mutalib. (2023). methylation profile of cancer testis antigens in colorectal cancer. - iranian journal of immunology. 83-91.
nor azila ma, nor azian am, azmawati mn, sharifah azura s, petrick p, najma k, mohd rohaizat h, norfazilah a, anita s, hanita o, tuti ningseh md, nurul syakima am, ezanee azlina, siti aishah, nurul syeefa', abdul rashid, abdul halim, hanafiah hr, rahman j. (2021). covid-19 in malaysia: exposure assessment and prevention practices among healthcare workers at a teaching hospital. - journal of infection in developing countries. 1816-1824.
nur fadhlina mohamad pakarulrazy, saiful effendi syafruddin, nurul syakima ab mutalib, azlina ahmad annuar, shen yang lim, rahman jamal, nor azian abdul murad, norlinah mohamed ibrahim. (2020). glucocerebrosidase genetic variants in malays with early and late-onset parkinson's disease. - neurology asia. 39-46.
siti a sulaiman, nadiah abu, nurul-syakima ab mutalib, teck yew low, rahman jamal. (2019). signatures of gene expression, dna methylation and micrornas of hepatocellular carcinoma with vascular invasion. - future oncology. 2603-2617.
hooi-leng ser, wen-si tan, nurul-syakima ab mutalib, wai-fong yin, kok-gan chan, bey-hing goh, learn-han lee. (2018). genome sequence of streptomyces gilvigriseus musc 26t isolated from mangrove forest. - brazilian journal of microbiology. .
nadiah abu, nurul ainaa adilah rus bakarurraini, siti nurmi nasir, muhiddin ishak, rashidah baharuddin, rahman jamal, nurul syakima ab mutalib. (2023). methylation profile of cancer testis antigens in colorectal cancer. - iranian journal of immunology. 83-91.
ryia illani my, nurul-syakima am, jia-shiun k, sazuita s, muhiddin i, saiful effendi s, francis yew ft, najwa farhah my, mohd ridhwan ar, norshahidah mn, nadiah a, isa md rose, ismail sagap, luqman mazlan, rahman jamal. (2023). whole genome sequencing of malaysian colorectal cancer patients reveals specific druggable somatic mutations. - frontiers in molecular biosciences. 1-20.
wan fahmi wmn, azliana my, francis yft, nur fadhlina mp, rohaizak m, shahrun niza as, nani harlina ml, sazuita s, isa mr, learn-han lee, nurul-syakima am. (2022). differential gene expression analysis of papillary thyroid carcinoma reveals important genes for lymph node metastasis. - progress in microbes and molecular biology. 1-19.
mohd amin azuwar, nor azlan nor muhammad, nor afiqah-aleng, nurul-syakima ab mutalib, najwa farhah md. yusof, ryia illani mohd yunos, muhiddin ishak, sazuita saidin, isa mohamed rose, ismail sagap, luqman mazlan, zairul azwan mohd azman, musalmah mazlan. (2022). tcga-my: a systematic repository for systems biology of malaysian colorectal cancer. - life. 1-14.
rashidah baharudin, nurul qistina rus bakarurraini, imilia ismail, learn-han lee, nurul syakima ab mutalib. (2022). microrna methylome signature and their functional roles in colorectal cancer diagnosis, prognosis and chemoresistance. - international journal of molecular sciences. 1-21.
muhiddin ishak, nadiah abu, nurul syakima ab mutalib. (2020). metilasi dna : pengaruh dalam kanser. - . 117.
azliana mohamad yusof, nurul syakima ab mutalib. (2020). teknologi mikrorna: aplikasi dalam rawatan kanser. - . 137.
nurul-syakima ab mutalib, rashidah baharuddin, rahman jamal. (2019). computational epigenetics and diseases. - . 22.
nurul-syakima ab mutalib, rashidah baharuddin, rahman jamal. (2019). computational epigenetics and diseases. - . 22.
saiful effendi syafruddin, mohamad aimanuddin mohtar, tan shing cheng, nadiah abu, nor aidatulakma abdullah@muda, nurul syakima ab mutalib, chin siok fong, neoh hui min, rahman jamal, nor azian abdul murad. (2019). malaysian higher institution centres of excellence (hicoe) official compendium. - . 244.
nurul-syakima ab mutalib, siti aishah sulaiman and rahman jamal. (2019). computational epigenetics and diseases. - . 452.
vengadesh letchumanan, kok-gan chan, tahir m. khan, sarah i. bukhari, nurul-syakima ab mutalib, bey-hing goh and learn-han lee. (2018). vibrionaceae diversity, multidrug resistance and management. - . 6.
vengadesh letchumanan, hooi-leng ser, wen-si tan, nurul-syakima ab mutalib,bey-hing goh, kok-gan chan, learn-han lee. (2018). game changer-next generation sequencing and its impact on food microbiology. - . 302.
azliana mohamad yusof, nurul syakima ab mutalib. (2020). teknologi mikrorna: aplikasi dalam rawatan kanser. - . 137.
muhiddin ishak, nadiah abu, nurul syakima ab mutalib. (2020). metilasi dna : pengaruh dalam kanser. - . 117.
nadiah binti abu;a. rahman bin a. jamal;luqman bin mazlan;nurul syakima binti ab mutalib;wan fahmi bin wan mohamad nazarie. (2022). in-depth characterisation of circulating tumour cells in metastatic colorectal cancer via single cell mrna sequencing. - . .
nurul syakima binti ab mutalib;a. rahman bin a. jamal;ismail bin sagap;luqman bin mazlan;zairul azwan bin mohd azman;isa b mohamed rose. (2022). integrated methylome and transcriptome analysis of colorectal cancers through epigenome wide approach. - . .
chuah jwy , nani hml , rohaizak m , nurul syakima , nadiah abu , nurdashima as , mustangin m. (2022). micrornas targeting gene proteins & their expression levels in triple negative breast cancers (tnbc): a cross sectional study. - assessment of dissertation defense day. 29.
nadiah abu, nurul ainaa adilah rus bakarruraini, rashidah baharudin, muhiddin ishak, nurul syakima ab mutalib. (2022). methylation profile of cancer testis antigens in malaysian colorectal cancer patients. - 5th international meeting on intestinal diseases in conjunction with the annual congress of the korean association for the study of intestinal diseases 2022 (imkasid 2022). 1.
francis yew fu tieng, nurul syakima ab mutalib. (2022). transkriptom sel tunggal dalam kanser kolorektal - aplikasi dalam metastasis, rintangan terhadap rawatan kemoterapi dan peranan sel tumor beredar. - . 1-2.
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| ELUCIDATING THE ROLES OF LONG NONCODING RNAS (LNCRNAS) FROM LIPOTOXIC HEPATOCYTE-EXTRACELLULAR VESICLES (HEPATOCYTE-EVS) IN THE LIVER FIBROSIS FORMATION | biotek abadi sdn bhd | 82.5% (2021-09-01 sehingga 2024-02-29) |
| IN-DEPTH INVESTIGATION OF CHROMATIN ACCESSIBILITY IN COLORECTAL CANCER CIRCULATING TUMOUR CELLS VIA SINGLE CELL ATAC-SEQ | biomed global | 79.3% (2021-06-01 sehingga 2024-04-30) |
| IMMUNO-CAPTURE OF CIRCULATING GALECTIN 9-BOUND EXTRACELLULAR VESICLES USING SUPERPARAMAGNETIC BEADS VIA CONVENTIONAL FLOW CYTOMETRY | biomed global | 68.7% (2023-01-16 sehingga 2024-01-15) |