prof. madya dr. nurul syakima binti ab mutalib

pensyarah universiti

institut biologi molekul perubatan ukm (umbi)

 syakima@ukm.edu.my



   Biografi/ Biography :


  • I am a scientist and academician in medical molecular biology. I`ve been fortunate to contribute to cancer research, molecular diagnostics, and epigenetics over the years. My focus on molecular medicine and noncoding RNA has allowed me to play a part in Malaysia`s scientific community. My research on circulating tumor cells and single-cell transcriptomics of colorectal cancer has been recognized by my peers, which I consider a great honor. I`ve held leadership positions, including team leader in cancer genomics and biobanking, Chief Technical Officer, and Head of Quality Assurance. I`ve had the opportunity to collaborate with institutions worldwide, including a fellowship at the Institute of Genomic Medicine at Newcastle University, England. I was awarded several grants and awards from organizations such as Qiagen, Korean Cancer Association and the Hong Kong Institute of Digestive Disease. I`ve held various positions, including Application Scientist at Science Vision Sdn Bhd, Visiting Fellow at Newcastle University, Associate Fellow at the Faculty of Health Sciences, UKM, and Adjunct Senior Lecturer at Monash University.

  • francis yew fu tieng, muhammad-redha abdullah-zawawi, nur alyaa afifah md shahri, zeti-azura mohamed-hussein, learn-han lee, nurul-syakima ab mutalib.  (2024).  a hitchhiker's guide to rna-rna structure and interaction prediction tools.  - briefings in bioinformatics.  1-37. 

     

    low teck yew;a. rahman bin a. jamal;nurismah binti md isa;razman bin jarmin;azlanudin bin azman;nurul syakima binti ab mutalib;nadiah binti abu.  (2024).  elucidating the proteogenomic signatures of hepatocellular carcinoma (hcc) in the malaysian population.  -

     

    ahmad zulkefly, wan norlina wan azman, julia omar, nurul syakima ab mutalib, desy fitrya syamsumir, m maulidiani, faridah abas, maya mazuwin yahya, muhamad syahmi yamin, wan faiziah wan abdul rahman, tengku ahmad damitri al-astani tengku din.  (2023).  identification of potential biomarkers and metabolic changes in the serum of breast lump patients among kelantanese based on 1h nmr metabolomics.  - progress in microbes & molecular biology.  1-18. 

     

    muhammad nafiz haidi adrus, vicneswarry dorairaj, nadiah abu, nurul syakima ab mutalib, khairul najmi muhammad nawawi, siti aishah sulaiman.  (2023).  characterisation of extracellular vesicle released from hepatocytes with excessive lipid accumulation.  - medicine & health.  21-22. 

     

    nur alia natasya zabidi, rashidah baharudin, nurul qistina rus bakarurraini, nur alyaa afifah md shahri, francis tieng yew fu, imilia ismail, muhammad redha abdullah zawawi, jodi woan-fei law, learn-han lee, nurul-syakima ab mutalib.  (2023).  investigating dna methylation of solute carrier genes in colorectal cancer: a comprehensive analysis using microarray and bioinformatics tools.  - progress in microbes and molecular biology.  1-19. 

     

    francis yew fu tieng, muhammad-redha abdullah-zawawi, nur alyaa afifah md shahri, zeti-azura mohamed-hussein, learn-han lee, nurul-syakima ab mutalib.  (2024).  a hitchhiker's guide to rna-rna structure and interaction prediction tools.  - briefings in bioinformatics.  1-37. 

     

    ryia illani my, nurul-syakima am, jia-shiun k, sazuita s, muhiddin i, saiful effendi s, francis yew ft, najwa farhah my, mohd ridhwan ar, norshahidah mn, nadiah a, isa md rose, ismail sagap, luqman mazlan, rahman jamal.  (2023).  whole genome sequencing of malaysian colorectal cancer patients reveals specific druggable somatic mutations.  - frontiers in molecular biosciences.  1-20. 

     

    mohd amin azuwar, nor azlan nor muhammad, nor afiqah-aleng, nurul-syakima ab mutalib, najwa farhah md. yusof, ryia illani mohd yunos, muhiddin ishak, sazuita saidin, isa mohamed rose, ismail sagap, luqman mazlan, zairul azwan mohd azman, musalmah mazlan.  (2022).  tcga-my: a systematic repository for systems biology of malaysian colorectal cancer.  - life.  1-14. 

     

    rashidah baharudin, nurul qistina rus bakarurraini, imilia ismail, learn-han lee, nurul syakima ab mutalib.  (2022).  microrna methylome signature and their functional roles in colorectal cancer diagnosis, prognosis and chemoresistance.  - international journal of molecular sciences.  1-21. 

     

    rashidah baharudin, muhiddin ishak, azliana muhamad yusof, sazuita saidin, saiful effendi syafruddin, wan fahmi wan mohamad nazarie, learn-han lee, nurul-syakima ab mutalib.  (2022).  epigenome-wide dna methylation profiling in colorectal cancer and normal adjacent colon using infinium human methylation 450k.  - diagnostics.  1-22. 

     

    nadiah abu, nurul ainaa adilah rus bakarurraini, siti nurmi nasir, muhiddin ishak, rashidah baharuddin, rahman jamal, nurul syakima ab mutalib.  (2023).  methylation profile of cancer testis antigens in colorectal cancer.  - iranian journal of immunology.  83-91. 

     

    nor azila ma, nor azian am, azmawati mn, sharifah azura s, petrick p, najma k, mohd rohaizat h, norfazilah a, anita s, hanita o, tuti ningseh md, nurul syakima am, ezanee azlina, siti aishah, nurul syeefa', abdul rashid, abdul halim, hanafiah hr, rahman j.  (2021).  covid-19 in malaysia: exposure assessment and prevention practices among healthcare workers at a teaching hospital.  - journal of infection in developing countries.  1816-1824. 

     

    nur fadhlina mohamad pakarulrazy, saiful effendi syafruddin, nurul syakima ab mutalib, azlina ahmad annuar, shen yang lim, rahman jamal, nor azian abdul murad, norlinah mohamed ibrahim.  (2020).  glucocerebrosidase genetic variants in malays with early and late-onset parkinson's disease.  - neurology asia.  39-46. 

     

    siti a sulaiman, nadiah abu, nurul-syakima ab mutalib, teck yew low, rahman jamal.  (2019).  signatures of gene expression, dna methylation and micrornas of hepatocellular carcinoma with vascular invasion.  - future oncology.  2603-2617. 

     

    hooi-leng ser, wen-si tan, nurul-syakima ab mutalib, wai-fong yin, kok-gan chan, bey-hing goh, learn-han lee.  (2018).  genome sequence of streptomyces gilvigriseus musc 26t isolated from mangrove forest.  - brazilian journal of microbiology. 

     

    francis yew fu tieng, muhammad-redha abdullah-zawawi, nur alyaa afifah md shahri, zeti-azura mohamed-hussein, learn-han lee, nurul-syakima ab mutalib.  (2024).  a hitchhiker's guide to rna-rna structure and interaction prediction tools.  - briefings in bioinformatics.  1-37. 

     

    ryia illani my, nurul-syakima am, jia-shiun k, sazuita s, muhiddin i, saiful effendi s, francis yew ft, najwa farhah my, mohd ridhwan ar, norshahidah mn, nadiah a, isa md rose, ismail sagap, luqman mazlan, rahman jamal.  (2023).  whole genome sequencing of malaysian colorectal cancer patients reveals specific druggable somatic mutations.  - frontiers in molecular biosciences.  1-20. 

     

    nadiah abu, nurul ainaa adilah rus bakarurraini, siti nurmi nasir, muhiddin ishak, rashidah baharuddin, rahman jamal, nurul syakima ab mutalib.  (2023).  methylation profile of cancer testis antigens in colorectal cancer.  - iranian journal of immunology.  83-91. 

     

    muhammad harith bin nor ashimi, wan rohani wan taib, imilia ismail, nurul syakima ab mutalib, siti mariam rahim.  (2023).  the regulatory role of mirna towards expressed genes in the pathogenesis of gout: a review.  - human gene.  1-6. 

     

    syarah syamimi mohamed, azmir ahmad, nurul syakima ab mutalib, tengku ahmad damitri al-astani tengku, md salzihan md salleh, andee dzulkarnaen zakaria, zaidi zakaria.  (2023).  a panel of three microrna signatures as a potential biomarker for crc screening based on stages and functional prediction using bioinformatic analysis.  - progress in microbes and molecular biology.  1-17. 

     

    muhiddin ishak, nadiah abu, nurul syakima ab mutalib.  (2020).  metilasi dna : pengaruh dalam kanser.  - 117. 

     

    azliana mohamad yusof, nurul syakima ab mutalib.  (2020).  teknologi mikrorna: aplikasi dalam rawatan kanser.  - 137. 

     

    nurul-syakima ab mutalib, rashidah baharuddin, rahman jamal.  (2019).  computational epigenetics and diseases.  - 22. 

     

    nurul-syakima ab mutalib, rashidah baharuddin, rahman jamal.  (2019).  computational epigenetics and diseases.  - 22. 

     

    saiful effendi syafruddin, mohamad aimanuddin mohtar, tan shing cheng, nadiah abu, nor aidatulakma abdullah@muda, nurul syakima ab mutalib, chin siok fong, neoh hui min, rahman jamal, nor azian abdul murad.  (2019).  malaysian higher institution centres of excellence (hicoe) official compendium.  - 244. 

     

    nurul-syakima ab mutalib, siti aishah sulaiman and rahman jamal.  (2019).  computational epigenetics and diseases.  - 452. 

     

    vengadesh letchumanan, kok-gan chan, tahir m. khan, sarah i. bukhari, nurul-syakima ab mutalib, bey-hing goh and learn-han lee.  (2018).  vibrionaceae diversity, multidrug resistance and management.  - 6. 

     

    vengadesh letchumanan, hooi-leng ser, wen-si tan, nurul-syakima ab mutalib,bey-hing goh, kok-gan chan, learn-han lee.  (2018).  game changer-next generation sequencing and its impact on food microbiology.  - 302. 

     

    azliana mohamad yusof, nurul syakima ab mutalib.  (2020).  teknologi mikrorna: aplikasi dalam rawatan kanser.  - 137. 

     

    muhiddin ishak, nadiah abu, nurul syakima ab mutalib.  (2020).  metilasi dna : pengaruh dalam kanser.  - 117. 

     

    low teck yew;a. rahman bin a. jamal;nurismah binti md isa;razman bin jarmin;azlanudin bin azman;nurul syakima binti ab mutalib;nadiah binti abu.  (2024).  elucidating the proteogenomic signatures of hepatocellular carcinoma (hcc) in the malaysian population.  -

     

    francis yew fu tieng, nadiah abu, sazuita saidin, zairul azwan mohd azman, see hui shien, edward chee, muhd khairul luqman bin muhd sakaff, learn-han lee and nurul-syakima ab mutalib.  (2023).  deciphering tumour heterogeneity and transcriptomic profiles of circulating tumor cells in archived metastatic colorectal cancer samples via single-cell mrna sequencing.  - 4th edition of international precision medicine conference.  1-3. 

     

    nurul-syakima ab mutalib, francis yew fu tieng, nadiah abu, sazuita saidin, zairul azwan mohd azman, see hui shien, edward chee, muhd khairul luqman bin muhd sakaff, learn-han lee.  (2023).  unraveling cancer stem cell signatures in circulating tumor cells of metastatic colorectal cancer: investigating aldh1a1 and the repurposing potential of disulfiram via scrna-seq.  - 4th edition of international precision medicine conference.  1-4. 

     

    nurul syakima ab mutalib.  (2023).  revolutionizing colorectal cancer treatment: the power of sustainable precision drug repurposing with biomarkers from epigenetics and single-cell rna sequencing.  - 1-18. 

     

    nurul syakima ab mutalib.  (2023).  an interview on the sidelines of the 2023 mustafa(pbuh) prize.  - presstv iran.