pensyarah universiti
institut biologi molekul perubatan ukm (umbi)
syakima@ukm.edu.my
Kluster Kepakaran/ Cluster of Expertise :
Kesihatan dan Perubatan Termaju,
Biografi/ Biography :
I am a scientist and academician in medical molecular biology. I`ve been fortunate to contribute to cancer research, molecular diagnostics, and epigenetics over the years. My focus on molecular medicine and noncoding RNA has allowed me to play a part in Malaysia`s scientific community.
My research on circulating tumor cells and single-cell transcriptomics of colorectal cancer has been recognized by my peers, which I consider a great honor. I`ve held leadership positions, including team leader in cancer genomics and biobanking, Chief Technical Officer, and Head of Quality Assurance.
I`ve had the opportunity to collaborate with institutions worldwide, including a fellowship at the Institute of Genomic Medicine at Newcastle University, England. I was awarded several grants and awards from organizations such as Qiagen, Korean Cancer Association and the Hong Kong Institute of Digestive Disease.
I`ve held various positions, including Application Scientist at Science Vision Sdn Bhd, Visiting Fellow at Newcastle University, Associate Fellow at the Faculty of Health Sciences, UKM, and Adjunct Senior Lecturer at Monash University.
khairunnisa mohd kamal, ahmad rohi ghazali, gayathri thevi selvarajah, nurul syakima ab mutalib, nadiah abu, eng wee chua, siti fathiah masre. (2025). histopathological evaluation of a dna methyltransferase inhibitor in an ntcu-induced dual-stage lung carcinogenesis mouse model. - american association for cancer research on campus. .
khairunnisa mohd kamal, ahmad rohi ghazali, gayathri thevi selvarajah, nurul syakima ab mutalib, nadiah abu, eng wee chua, siti fathiah masre. (2025). freezing tissues pre-homogenisation reduces degradation and yields improved quality rna in the mouse lung. - biochemistry and biophysics reports. 1 - 4.
lim c.l, ab mutalib n.s., masre s.f., azmi f.b., nik eezamuddeen m., abdul murad n.a. abu n.. (2025). extracellular vesicle profiling reveals immunomodulatory changes in colorectal cancer: implications for early diagnosis and chemotherapy response. - 18th annual meeting of the korean society of medical oncology & 2025 international conference (ksmo 2025). .
nima rezaei. (2025). molecular markers in circulating tumour cells: advancing clinical precision. - interdisciplinary cancer research. 513 - 540.
nurul syakima ab mutalib. (2025). why r for doctors & researchers (invited talk by clinical research centre, hospital sungai buloh, kementerian kesihatan malaysia). - . .
francis yew fu tieng, learn-han lee & nurul-syakima ab mutalib . (2025). single-cell rna-sequencing of circulating tumour cells: a practical guide to workflow and translational applications. - cancer and metastasis reviews. 1 - 46.
francis yew fu tieng, muhammad-redha abdullah-zawawi, nur alyaa afifah md shahri, zeti-azura mohamed-hussein, learn-han lee, nurul-syakima ab mutalib. (2024). a hitchhiker’s guide to rna–rna structure and interaction prediction tools. - briefings in bioinformatics. 1 - 37.
khairunnisa mohd kamal, ahmad rohi ghazali, nurul syakima ab mutalib, nadiah abu, eng wee chua siti fathiah masre. (2024). the role of dna methylation and dna methyltransferases (dnmts) as potential biomarker and therapeutic target in non-small cell lung cancer (nsclc). - heliyon. 1 - 17.
nur farhana mohd nippah, nadiah abu, nurul syakima ab mutalib, hamidah alias. (2024). advances in next-generation sequencing for relapsed pediatric acute lymphoblastic leukemia: current insights and future directions. - frontiers in genetics. 1 - 9.
francis yew fu tieng, muhammad-redha abdullah-zawawi, nur alyaa afifah md shahri, zeti-azura mohamed-hussein, learn-han lee, nurul-syakima ab mutalib. (2024). a hitchhiker's guide to rna-rna structure and interaction prediction tools. - briefings in bioinformatics. 1-37.
habsah aziz, nurul syakima ab mutalib, hamidah alias, rahman jamal. (2024). whole genome sequencing reveals the mutational landscape from disease diagnosis to relapse in patients with childhood acute myeloid leukaemia. - malaysian journal of pathology. 259 - 278.
nadiah abu, nurul ainaa adilah rus bakarurraini, siti nurmi nasir, muhiddin ishak, rashidah baharuddin, rahman jamal, nurul syakima ab mutalib. (2023). methylation profile of cancer testis antigens in colorectal cancer. - iranian journal of immunology. 83-91.
nor azila ma, nor azian am, azmawati mn, sharifah azura s, petrick p, najma k, mohd rohaizat h, norfazilah a, anita s, hanita o, tuti ningseh md, nurul syakima am, ezanee azlina, siti aishah, nurul syeefa', abdul rashid, abdul halim, hanafiah hr, rahman j. (2021). covid-19 in malaysia: exposure assessment and prevention practices among healthcare workers at a teaching hospital. - journal of infection in developing countries. 1816-1824.
nur fadhlina mohamad pakarulrazy, saiful effendi syafruddin, nurul syakima ab mutalib, azlina ahmad annuar, shen yang lim, rahman jamal, nor azian abdul murad, norlinah mohamed ibrahim. (2020). glucocerebrosidase genetic variants in malays with early and late-onset parkinson's disease. - neurology asia. 39-46.
siti a sulaiman, nadiah abu, nurul-syakima ab mutalib, teck yew low, rahman jamal. (2019). signatures of gene expression, dna methylation and micrornas of hepatocellular carcinoma with vascular invasion. - future oncology. 2603-2617.
muhammad-redha abdullah-zawawi, muhammad irfan abdul jalal, shing cheng tan, loscheni varma, nur alyaa afifah md shahri, mira farzana mohamad mokhtar, ryia illani mohd yunos, nurul syakima ab mutalib, rahman jamal. (2025). bioinformatics-driven identification of key non-invasive prognostic biomarkers in hepatocellular carcinoma. - egyptian journal of medical human genetics. 1 - 16.
khairunnisa mohd kamal, ahmad rohi ghazali, gayathri thevi selvarajah, nurul syakima ab mutalib, nadiah abu, eng wee chua, siti fathiah masre. (2025). freezing tissues pre-homogenisation reduces degradation and yields improved quality rna in the mouse lung. - biochemistry and biophysics reports. 1 - 4.
francis yew fu tieng, learn-han lee & nurul-syakima ab mutalib . (2025). single-cell rna-sequencing of circulating tumour cells: a practical guide to workflow and translational applications. - cancer and metastasis reviews. 1 - 46.
nur fadhlina mohamad pakarulrazy, nadiah abu, shahrun niza abdullah suhaimi, nadzlee harith paisol, reena rahayu md zin, nani h. mdlatar, nurul syakima ab mutalib. (2025). gene expression analysis of papillary thyroid carcinoma with lymph node metastasis and radioiodine refractivity. - cureus. 1 - 22.
khairunnisa mohd kamal, ahmad rohi ghazali, nurul syakima ab mutalib, nadiah abu, eng wee chua siti fathiah masre. (2024). the role of dna methylation and dna methyltransferases (dnmts) as potential biomarker and therapeutic target in non-small cell lung cancer (nsclc). - heliyon. 1 - 17.
muhammad-redha abdullah-zawawi, seow neng chan, francis yew fu tieng, zeti-azura mohamed-hussein, and nurul-syakima ab mutalib. (2025). drug repositioning using single-cell rna sequencing in cancer research. - . 635 - 666.
lina rozano, muhammad irfan abdul jalal, nur alyaa afifah md shahri, zeti-azura mohamed-hussein, nurul syakima ab mutalib, muhammad-redha abdullah-zawawi. (2025). molecular fingerprints and pharmacophores for computational drug repurposing. - . 746 - 756.
nima rezaei. (2025). molecular markers in circulating tumour cells: advancing clinical precision. - interdisciplinary cancer research. 513 - 540.
siti aishah sulaiman, muhammad nafiz haidi adrus, vicneswarry dorairaj, nadiah abu, nurul syakima ab mutalib, khairul najmi muhammad nawawi, nor azian abdul murad. (2024). 4.11 - stem cells and extracellular vesicles for prevention and treatment of liver fibrosis. - reference work. 146 - 158.
nurul-syakima ab mutalib, rashidah baharuddin, rahman jamal. (2019). epigenome-wide analysis of dna methylation in colorectal cancer. - translational epigenetics series. 289-310.
habsah aziz, rahman jamal, nurul syakima ab mutalib. (2024). kanser darah putih: kod rahsia jujukan dna kanak kanak . - . .
francis yew fu tieng, nurul syakima ab mutalib. (2022). transkriptom sel tunggal dalam kanser kolorektal - aplikasi dalam metastasis, rintangan terhadap rawatan kemoterapi dan peranan sel tumor beredar. - . 1-2.
nurul syakima ab mutalib, tan shing cheng, siti aishah sulaiman, rahman jamal. (2020). adakah anda mewarisi gen untuk risiko serangan jantung?. - . 1.
muhiddin ishak, nadiah abu, nurul syakima ab mutalib. (2020). metilasi dna : pengaruh dalam kanser. - . 117.
azliana mohamad yusof, nurul syakima ab mutalib. (2020). teknologi mikrorna: aplikasi dalam rawatan kanser. - . 137.
khairunnisa mohd kamal, ahmad rohi ghazali, gayathri thevi selvarajah, nurul syakima ab mutalib, nadiah abu, eng wee chua, siti fathiah masre. (2025). histopathological evaluation of a dna methyltransferase inhibitor in an ntcu-induced dual-stage lung carcinogenesis mouse model. - american association for cancer research on campus. .
lim c.l, ab mutalib n.s., masre s.f., azmi f.b., nik eezamuddeen m., abdul murad n.a. abu n.. (2025). extracellular vesicle profiling reveals immunomodulatory changes in colorectal cancer: implications for early diagnosis and chemotherapy response. - 18th annual meeting of the korean society of medical oncology & 2025 international conference (ksmo 2025). .
nurul syakima ab mutalib. (2025). from raw reads to real insights (for invited lecture series hgc by universiti sains malaysia). - . .
nurul syakima ab mutalib. (2025). from research to recognition: mastering the art of writing and publishing in high-impact journals. - . .
nurul syakima ab mutalib. (2025). gene therapy & genetic engineering in cancer (for invited lecture um x curie masterclass of cancer molecular biology). - . .
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| COMPARISON OF MUTATIONAL LANDSCAPE BETWEEN PRIMARY AND RECURRENT LARYNGEAL SQUAMOUS CELL CARCINOMA | kpj healthcare university sdn bhd | 53.4% (2024-12-01 sehingga 2026-11-30) |
BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
Molecular Biology, Noncoding RNA, Epigenetics, DNA methylation, MicroRNAs
Pengalaman / Experience : 12 tahun/years(s)
BIOLOGY :PURE AND APPLIED SCIENCES
Next Generation Sequencing, Transcriptomics, Single cell RNA sequencing, Whole Genome Sequencing, Whole exome sequencing, Targeted sequencing, Microarray, qPCR, Bioinformatics ,,,,,,,,,,
Pengalaman / Experience : 12 tahun/years(s)
ONCOLOGY :CLINICAL AND HEALTH SCIENCES
Cancer biomarkers, Non-coding RNAs, Transcriptomics, Cell Culture, Liquid Biopsy, Circulating tumour cells
Pengalaman / Experience : 16 tahun/years(s)
BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
NONCODING RNA
Pengalaman / Experience : 11 tahun/years(s)