dr. lam su datt

pensyarah universiti

jabatan fizik gunaan

No. sambungan :  0389213833

No. rasmi:
UKM : 03 8921 5555



   Biografi/ Biography :

  • Advances in sequencing techniques gave rise to the rapid increase of new sequences. Yet, resolving the protein structure is complicated and time-consuming, creating an ever-widening “Protein structure gap”. With a mission to narrow the gap using computational tools, Su Datt pursued his PhD in Bioinformatics at University College London. Obtaining a good template is key to the success of protein structure modelling. During his PhD, he developed a template searching protocol that produced higher percentages of good quality modes compared to the state-of-the-art template searching protocol. His modelling platform has been applied to model >70% of the structurally uncharacterised proteins for >14 model organisms. After graduated from his PhD, he embarked on a study to understand the biological impacts of mutually exclusive exon splicing (MXE) in 5 different genomes. MXE-specific residues tend to be surface exposed and cluster near protein functional sites. MXEs tend to maintain the protein fold, but alter the specificity and selectivity of protein functions. These results suggest MXEs may have some important roles in cells and also in cancer. He recently acquired a research grant to study the structure of proteins found in a fungus living in Antarctica. Studying proteins found in harsh environment may lead to the finding of new enzymes that may be in industrial applications or possible bioproducts.

  • ian sillitoe, nicola bordin, natalie dawson, vaishali waman, paul ashford, harry scholes, csm pang, l. woodridge, c. rauer, n. sen, m. abbasian, sean le cornu, su datt lam, karel berka, ivana varekova, radka svobodova, jon lees and christine a. orengo.  (2021).  cath: increased structural coverage of functional space.  - nucleic acids research.  D266-D273. 

     

    khairul azreena bakar, su datt lam, hasidah mohd sidek, shevin rizal feroz.  (2020).  characterization of the interaction of diosgenin with human serum albumin and alpha1-acid glycoprotein using biophysical and bioinformatic tools.  - journal of molecular liquids.  1-10. 

     

    how shu sian, lam su datt, sylvia chieng.  (2020).  characterisation of burkholderia pseudomallei sugar abc transporter using bioinformatics approach.  - msab2020 virtual seminar.  52. 

     

    xin-wei lee, su datt lam, mohd firdaus-raih, kiew-lian wan.  (2020).  molecular characterisation of eimeria tenella porin, a potential anticoccidial drug target.  - sains malaysiana.  755-764. 

     

    su datt lam, nicola bordin, vaishali waman, harry scholes, paul ashford, neeladri sen, lucy van dorp, clemens rauer, natalie dawson, camilla pang, mahnaz abbasian, ian sillitoe, s. edwards, f. fraternali, jonathan lees, joanne santini, christine orengo.  (2020).  sars-cov-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals.  - nature scientific reports.  1-14. 

     

    ian sillitoe, nicola bordin, natalie dawson, vaishali waman, paul ashford, harry scholes, csm pang, l. woodridge, c. rauer, n. sen, m. abbasian, sean le cornu, su datt lam, karel berka, ivana varekova, radka svobodova, jon lees and christine a. orengo.  (2021).  cath: increased structural coverage of functional space.  - nucleic acids research.  D266-D273. 

     

    khairul azreena bakar, su datt lam, hasidah mohd sidek, shevin rizal feroz.  (2020).  characterization of the interaction of diosgenin with human serum albumin and alpha1-acid glycoprotein using biophysical and bioinformatic tools.  - journal of molecular liquids.  1-10. 

     

    su datt lam, nicola bordin, vaishali waman, harry scholes, paul ashford, neeladri sen, lucy van dorp, clemens rauer, natalie dawson, camilla pang, mahnaz abbasian, ian sillitoe, s. edwards, f. fraternali, jonathan lees, joanne santini, christine orengo.  (2020).  sars-cov-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals.  - nature scientific reports.  1-14. 

     

    ian sillitoe, antonina andreeva, tom l. blundell, daniel buchan, robert finn, julian gough, david jones, lawrence a. kelley, typhaine paysan-lafosse, su datt lam, ..., christine orengo.  (2020).  genome3d: integrating a collaborative data pipeline to expand the depth and breadth of consensus protein structure annotation.  - nucleic acids research.  D314-D319. 

     

    nyuk ling ma , wan afifudeen che lah, nisrin abd. kadir, mohamad mustaqim, zaidah rahmat, aziz ahmad, su datt lam, mohd razi ismail.  (2018).  susceptibility and tolerance of rice crop to salt threat: physiological and metabolic inspections.  - plos one. 

     

    xin-wei lee, su datt lam, mohd firdaus-raih, kiew-lian wan.  (2020).  molecular characterisation of eimeria tenella porin, a potential anticoccidial drug target.  - sains malaysiana.  755-764. 

     

    natalie l. dawson, ian sillitoe, jonathan g. lees, su datt lam & christine a. orengo.  (2017).  protein bioinformatics from protein modifications and networks to proteomics.  - 32. 

     

    how shu sian, lam su datt, sylvia chieng.  (2020).  characterisation of burkholderia pseudomallei sugar abc transporter using bioinformatics approach.  - msab2020 virtual seminar.  52. 

     

    su datt lam, m. madan babu, jonathan lees , christine a. orengo.  (2019).  structural and function analyses to understand impacts of mutually exclusive exon splicing.  - dsx conference 2019.  24. 

     

    syaza safia fouzi, mohd asyraf shamsuddin, norefrina shafinaz md nor, nazlina ibrahim.  (2019).  in silico study of the interaction between a styrylpyrone deriva tive with target proteins of human herpes virus1.  - the international congress of the malaysia society for microbiology 2019 (icmsm2019).  43.