pensyarah universiti
institut perubatan molekul (umbi)
No. rasmi:
UKM : 03 8921 5555
Biografi/ Biography :
M. Aiman Mohtar is a Research Fellow at the UKM Medical Molecular Biology Institute (UMBI), The National University of Malaysia. He previously earned his BSc. (Biotechnology) with highest honours from Rochester Institute of Technology, New York and MSc. (Molecular Biology) from University of Pennsylvania, Philadelphia. He completed his PhD in Molecular and Clinical Medicine at Institute of Genetics and Molecular Medicine, University of Edinburgh. His PhD thesis focuses on identification of protein-protein interaction network of an oncogenic ER-resident protein. He has been trained as molecular biologist for more than a decade and has involved in research utilizing cutting- edge laboratory techniques such as CRISPR-Cas9 gene editing tools, fluorescence microscopy, phage display and quantitative proteomics. Aiman’s current research focus is studying protein-protein interaction and tumour cell secretory addiction in AGR2 signalling axis using multi-omics approach and developing therapeutic tools targeting pro-oncogenic molecules.
syazalina zahari, saiful effendi syafruddin and m. aiman mohtar. (2023). impact of the cancer cell secretome in driving breast cancer progression. - cancers. 1-17.
asmaa y. abuhamad, nurul nadia mohamad zamberi, sakari vanharanta, siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin. (2023). cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma. - international journal of molecular sciences. 1-14.
saiful effendi bin syafruddin;muhiddin bin ishak;mohamad aimanuddin bin mohtar;low teck yew. (2023). functional validation of crispr-cas9 genetic screening hit hsf4 in supporting clear cell renal cell carcinoma pathogenesis. - . .
saiful effendi syafruddin, nurul nadia mohamad zamberi, asmaa y. abuhamad. sarah izzati izzat azrai, mohd khairul nizam mohd khalid , m. aiman mohtar. (2023). super enhancer-associated glucocorticoid receptor nr3c1 supports renal carcinoma growth by transcriptionally regulating the expression of pdk4, edn2 and il-6. - 15th malaysia international genetics congress 2023. 1-19.
ahmad rifqi bin md zain;tengku hasnan bin tengku abdul aziz;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar. (2023). optical sensor technique based on high quality factor suspended 1d photonic crystal (phc) structures for creatinine detection using non-invasive approach.. - . .
syazalina zahari, saiful effendi syafruddin and m. aiman mohtar. (2023). impact of the cancer cell secretome in driving breast cancer progression. - cancers. 1-17.
asmaa y. abuhamad, nurul nadia mohamad zamberi, sakari vanharanta, siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin. (2023). cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma. - international journal of molecular sciences. 1-14.
asmaa y. abuhamad, nurul nadia mohamad zamberi, ling sheen, safaa m. naes, siti nur hasanah mohd yusuf, asilah ahmad tajudin, m. aiman mohtar, amir syahir amir hamzah, saiful effendi syafruddin. (2022). reverting tp53 mutation in breast cancer cells: prime editing workflow and technical considerations. - cells. 1-16.
alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low. (2022). short open reading frames (sorfs) and microproteins: an update on their identification and validation measures. - journal of biomedical science. 1-15.
nisa syakila a. rahman, syazalina zahari, saiful effendi syafruddin, mohd firdaus-raih, teck yew low, m. aiman mohtar. (2022). functions and mechanisms of protein disulfide isomerase family in cancer emergence. - cell & bioscience. 1-19.
saiful effendi syafruddin, wan fahmi wan mohamad nazarie, nurshahirah ashikin moidu, bee hong soon, m. aiman mohtar. (2021). integration of rna-seq and proteomics data identifies glioblastoma multiforme surfaceome signature. - bmc cancer. 1-13.
syazalina zahari, saiful effendi syafruddin and m. aiman mohtar. (2023). impact of the cancer cell secretome in driving breast cancer progression. - cancers. 1-17.
asmaa y. abuhamad, nurul nadia mohamad zamberi, sakari vanharanta, siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin. (2023). cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma. - international journal of molecular sciences. 1-14.
asmaa y. abuhamad, nurul nadia mohamad zamberi, ling sheen, safaa m. naes, siti nur hasanah mohd yusuf, asilah ahmad tajudin, m. aiman mohtar, amir syahir amir hamzah, saiful effendi syafruddin. (2022). reverting tp53 mutation in breast cancer cells: prime editing workflow and technical considerations. - cells. 1-16.
alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low. (2022). short open reading frames (sorfs) and microproteins: an update on their identification and validation measures. - journal of biomedical science. 1-15.
nisa syakila a. rahman, syazalina zahari, saiful effendi syafruddin, mohd firdaus-raih, teck yew low, m. aiman mohtar. (2022). functions and mechanisms of protein disulfide isomerase family in cancer emergence. - cell & bioscience. 1-19.
saiful effendi syafruddin, mohamad aimanuddin mohtar, tan shing cheng, nadiah abu, nor aidatulakma abdullah@muda, nurul syakima ab mutalib, chin siok fong, neoh hui min, rahman jamal, nor azian abdul murad. (2019). malaysian higher institution centres of excellence (hicoe) official compendium. - . 244.
saiful effendi bin syafruddin;muhiddin bin ishak;mohamad aimanuddin bin mohtar;low teck yew. (2023). functional validation of crispr-cas9 genetic screening hit hsf4 in supporting clear cell renal cell carcinoma pathogenesis. - . .
ahmad rifqi bin md zain;tengku hasnan bin tengku abdul aziz;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar. (2023). optical sensor technique based on high quality factor suspended 1d photonic crystal (phc) structures for creatinine detection using non-invasive approach.. - . .
saiful effendi syafruddin, nurul nadia mohamad zamberi, asmaa y. abuhamad. sarah izzati izzat azrai, mohd khairul nizam mohd khalid , m. aiman mohtar. (2023). super enhancer-associated glucocorticoid receptor nr3c1 supports renal carcinoma growth by transcriptionally regulating the expression of pdk4, edn2 and il-6. - 15th malaysia international genetics congress 2023. 1-19.
low teck yew;mohd firdaus bin mohd raih;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar;lee pey yee. (2022). elucidating the mechanism of secretion for human pro-metastatic agr2 protein. - . .
saiful effendi syafruddin, mohamad aimanuddin mohtar. (2022). crispr-cas9 principles, applications and ethical issues. - . 1-61.
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| ELUCIDATING THE RESISTANCE OF COLORECTAL (CRC) CANCER CELL LINES TO FOLFOX, A CHEMOTHERAPEUTIC AGENT WITH QUANTITATIVE PROTEOMICS AND UBIQUITOMICS | sciex | 64.8% (2021-07-01 sehingga 2024-06-28) |
| ELUCIDATING THE MICROPROTEOME UNIQUELY EXPRESSED IN CELL LINES DERIVED FROM MULTIPLE STAGES OF COLORECTAL CANCER (CRC) | sciex | 95.2% (2020-08-01 sehingga 2023-07-31) |
| COMB STRUCTURED WEARABLE METAMATERIAL WITH ELECTRICAL CONDUCTIVITY FOR HEALTH MONITORING GARMENT OF SEVERE PATIENTS | kelisa technology sdn bhd | 88.6% (2021-09-01 sehingga 2023-08-31) |
| ELUCIDATING THE FUNCTIONAL LINK BETWEEN PROXIMAL SUPER ENHANCER LOCUS AND NR3C1 TRANSCRIPTIONAL REGULATION IN CLEAR CELL RENAL CELL CARCINOMA. | next gene scientific sdn bhd | 75.9% (2021-03-01 sehingga 2024-02-28) |
pensyarah universiti
institut biologi molekul perubatan ukm (umbi)
m.aimanmohtar@ppukm.ukm.edu.my
No. Telefon Rasmi : 9062
No. rasmi:
UKM : 03 8921 5555
Biografi/ Biography :
PENSYARAH UNIVERSITI
syazalina zahari, saiful effendi syafruddin and m. aiman mohtar. (2023). impact of the cancer cell secretome in driving breast cancer progression. - cancers. 1-17.
asmaa y. abuhamad, nurul nadia mohamad zamberi, sakari vanharanta, siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin. (2023). cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma. - international journal of molecular sciences. 1-14.
saiful effendi bin syafruddin;muhiddin bin ishak;mohamad aimanuddin bin mohtar;low teck yew. (2023). functional validation of crispr-cas9 genetic screening hit hsf4 in supporting clear cell renal cell carcinoma pathogenesis. - . .
saiful effendi syafruddin, nurul nadia mohamad zamberi, asmaa y. abuhamad. sarah izzati izzat azrai, mohd khairul nizam mohd khalid , m. aiman mohtar. (2023). super enhancer-associated glucocorticoid receptor nr3c1 supports renal carcinoma growth by transcriptionally regulating the expression of pdk4, edn2 and il-6. - 15th malaysia international genetics congress 2023. 1-19.
ahmad rifqi bin md zain;tengku hasnan bin tengku abdul aziz;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar. (2023). optical sensor technique based on high quality factor suspended 1d photonic crystal (phc) structures for creatinine detection using non-invasive approach.. - . .
syazalina zahari, saiful effendi syafruddin and m. aiman mohtar. (2023). impact of the cancer cell secretome in driving breast cancer progression. - cancers. 1-17.
asmaa y. abuhamad, nurul nadia mohamad zamberi, sakari vanharanta, siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin. (2023). cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma. - international journal of molecular sciences. 1-14.
asmaa y. abuhamad, nurul nadia mohamad zamberi, ling sheen, safaa m. naes, siti nur hasanah mohd yusuf, asilah ahmad tajudin, m. aiman mohtar, amir syahir amir hamzah, saiful effendi syafruddin. (2022). reverting tp53 mutation in breast cancer cells: prime editing workflow and technical considerations. - cells. 1-16.
alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low. (2022). short open reading frames (sorfs) and microproteins: an update on their identification and validation measures. - journal of biomedical science. 1-15.
nisa syakila a. rahman, syazalina zahari, saiful effendi syafruddin, mohd firdaus-raih, teck yew low, m. aiman mohtar. (2022). functions and mechanisms of protein disulfide isomerase family in cancer emergence. - cell & bioscience. 1-19.
saiful effendi syafruddin, wan fahmi wan mohamad nazarie, nurshahirah ashikin moidu, bee hong soon, m. aiman mohtar. (2021). integration of rna-seq and proteomics data identifies glioblastoma multiforme surfaceome signature. - bmc cancer. 1-13.
syazalina zahari, saiful effendi syafruddin and m. aiman mohtar. (2023). impact of the cancer cell secretome in driving breast cancer progression. - cancers. 1-17.
asmaa y. abuhamad, nurul nadia mohamad zamberi, sakari vanharanta, siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin. (2023). cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma. - international journal of molecular sciences. 1-14.
asmaa y. abuhamad, nurul nadia mohamad zamberi, ling sheen, safaa m. naes, siti nur hasanah mohd yusuf, asilah ahmad tajudin, m. aiman mohtar, amir syahir amir hamzah, saiful effendi syafruddin. (2022). reverting tp53 mutation in breast cancer cells: prime editing workflow and technical considerations. - cells. 1-16.
alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low. (2022). short open reading frames (sorfs) and microproteins: an update on their identification and validation measures. - journal of biomedical science. 1-15.
nisa syakila a. rahman, syazalina zahari, saiful effendi syafruddin, mohd firdaus-raih, teck yew low, m. aiman mohtar. (2022). functions and mechanisms of protein disulfide isomerase family in cancer emergence. - cell & bioscience. 1-19.
saiful effendi syafruddin, mohamad aimanuddin mohtar, tan shing cheng, nadiah abu, nor aidatulakma abdullah@muda, nurul syakima ab mutalib, chin siok fong, neoh hui min, rahman jamal, nor azian abdul murad. (2019). malaysian higher institution centres of excellence (hicoe) official compendium. - . 244.
saiful effendi bin syafruddin;muhiddin bin ishak;mohamad aimanuddin bin mohtar;low teck yew. (2023). functional validation of crispr-cas9 genetic screening hit hsf4 in supporting clear cell renal cell carcinoma pathogenesis. - . .
ahmad rifqi bin md zain;tengku hasnan bin tengku abdul aziz;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar. (2023). optical sensor technique based on high quality factor suspended 1d photonic crystal (phc) structures for creatinine detection using non-invasive approach.. - . .
saiful effendi syafruddin, nurul nadia mohamad zamberi, asmaa y. abuhamad. sarah izzati izzat azrai, mohd khairul nizam mohd khalid , m. aiman mohtar. (2023). super enhancer-associated glucocorticoid receptor nr3c1 supports renal carcinoma growth by transcriptionally regulating the expression of pdk4, edn2 and il-6. - 15th malaysia international genetics congress 2023. 1-19.
low teck yew;mohd firdaus bin mohd raih;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar;lee pey yee. (2022). elucidating the mechanism of secretion for human pro-metastatic agr2 protein. - . .
saiful effendi syafruddin, mohamad aimanuddin mohtar. (2022). crispr-cas9 principles, applications and ethical issues. - . 1-61.
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| ELUCIDATING THE RESISTANCE OF COLORECTAL (CRC) CANCER CELL LINES TO FOLFOX, A CHEMOTHERAPEUTIC AGENT WITH QUANTITATIVE PROTEOMICS AND UBIQUITOMICS | sciex | 64.8% (2021-07-01 sehingga 2024-06-28) |
| ELUCIDATING THE MICROPROTEOME UNIQUELY EXPRESSED IN CELL LINES DERIVED FROM MULTIPLE STAGES OF COLORECTAL CANCER (CRC) | sciex | 95.2% (2020-08-01 sehingga 2023-07-31) |
| COMB STRUCTURED WEARABLE METAMATERIAL WITH ELECTRICAL CONDUCTIVITY FOR HEALTH MONITORING GARMENT OF SEVERE PATIENTS | kelisa technology sdn bhd | 88.6% (2021-09-01 sehingga 2023-08-31) |
| ELUCIDATING THE FUNCTIONAL LINK BETWEEN PROXIMAL SUPER ENHANCER LOCUS AND NR3C1 TRANSCRIPTIONAL REGULATION IN CLEAR CELL RENAL CELL CARCINOMA. | next gene scientific sdn bhd | 75.9% (2021-03-01 sehingga 2024-02-28) |