pensyarah universiti
institut biologi molekul perubatan ukm (umbi)
m.aimanmohtar@ppukm.ukm.edu.my
Biografi/ Biography :
M. Aiman Mohtar is a Research Fellow at the UKM Medical Molecular Biology Institute (UMBI), The National University of Malaysia. He previously earned his BSc. (Biotechnology) with highest honours from Rochester Institute of Technology, New York and MSc. (Molecular Biology) from University of Pennsylvania, Philadelphia. He completed his PhD in Molecular and Clinical Medicine at Institute of Genetics and Molecular Medicine, University of Edinburgh. His PhD thesis focuses on identification of protein-protein interaction network of an oncogenic ER-resident protein. He has been trained as molecular biologist for more than a decade and has involved in research utilizing cutting- edge laboratory techniques such as CRISPR-Cas9 genome editing tools, fluorescence microscopy, phage display and quantitative proteomics. Aiman’s current research focus is studying protein-protein interaction and tumour cell secretory addiction in AGR2 signalling axis using multi-omics approach and developing therapeutic tools targeting pro-oncogenic molecules. To date, he has secured several UKM, national and international grants.
ahmad rifqi bin md zain;tengku hasnan bin tengku abdul aziz;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar. (2023). optical sensor technique based on high quality factor suspended 1d photonic crystal (phc) structures for creatinine detection using non-invasive approach.. - . .
yuh cai chia, sundharavalli ramayah , nurul nadia mohamad zamberi, mohamad aimanuddin mohtar , saiful effendi syafruddin. (2023). crispr/cas9: teknik penyuntingan dan modifikasi gen. - . 1.
syazalina zahari , saiful effendi syafruddin , m. aiman mohtar. (2023). cancer cell secretome in driving breast cancer progression. - scholarly community encyclopedia. 1-8.
m. aiman mohtar, syazalina zahari, nisa syakila a. rahman, saiful effendi, muhammad-redha abdullah-zawawi, teck yew low, ted hupp. (2023). rna-seq analysis of crispr-cas9 targeted agr2 of breast cancer cells reveals potential modulators of its expression and secretion. - esmo open. 6.
syazalina zahari, saiful effendi syafruddin and m. aiman mohtar. (2023). impact of the cancer cell secretome in driving breast cancer progression. - cancers. 1-17.
m. aiman mohtar, syazalina zahari, nisa syakila a. rahman, saiful effendi, muhammad-redha abdullah-zawawi, teck yew low, ted hupp. (2023). rna-seq analysis of crispr-cas9 targeted agr2 of breast cancer cells reveals potential modulators of its expression and secretion. - esmo open. 6.
asmaa y. abuhamad, nurul nadia mohamad zamberi, sakari vanharanta, siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin. (2023). cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma. - international journal of molecular sciences. 1-14.
syazalina zahari, saiful effendi syafruddin and m. aiman mohtar. (2023). impact of the cancer cell secretome in driving breast cancer progression. - cancers. 1-17.
asmaa y. abuhamad, nurul nadia mohamad zamberi, ling sheen, safaa m. naes, siti nur hasanah mohd yusuf, asilah ahmad tajudin, m. aiman mohtar, amir syahir amir hamzah, saiful effendi syafruddin. (2022). reverting tp53 mutation in breast cancer cells: prime editing workflow and technical considerations. - cells. 1-16.
alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low. (2022). short open reading frames (sorfs) and microproteins: an update on their identification and validation measures. - journal of biomedical science. 1-15.
saiful effendi syafruddin, wan fahmi wan mohamad nazarie, nurshahirah ashikin moidu, bee hong soon, m. aiman mohtar. (2021). integration of rna-seq and proteomics data identifies glioblastoma multiforme surfaceome signature. - bmc cancer. 1-13.
m. aiman mohtar, syazalina zahari, nisa syakila a. rahman, saiful effendi, muhammad-redha abdullah-zawawi, teck yew low, ted hupp. (2023). rna-seq analysis of crispr-cas9 targeted agr2 of breast cancer cells reveals potential modulators of its expression and secretion. - esmo open. 6.
syazalina zahari, saiful effendi syafruddin and m. aiman mohtar. (2023). impact of the cancer cell secretome in driving breast cancer progression. - cancers. 1-17.
asmaa y. abuhamad, nurul nadia mohamad zamberi, sakari vanharanta, siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin. (2023). cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma. - international journal of molecular sciences. 1-14.
asmaa y. abuhamad, nurul nadia mohamad zamberi, ling sheen, safaa m. naes, siti nur hasanah mohd yusuf, asilah ahmad tajudin, m. aiman mohtar, amir syahir amir hamzah, saiful effendi syafruddin. (2022). reverting tp53 mutation in breast cancer cells: prime editing workflow and technical considerations. - cells. 1-16.
alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low. (2022). short open reading frames (sorfs) and microproteins: an update on their identification and validation measures. - journal of biomedical science. 1-15.
saiful effendi syafruddin, mohamad aimanuddin mohtar, tan shing cheng, nadiah abu, nor aidatulakma abdullah@muda, nurul syakima ab mutalib, chin siok fong, neoh hui min, rahman jamal, nor azian abdul murad. (2019). malaysian higher institution centres of excellence (hicoe) official compendium. - . 244.
saiful effendi bin syafruddin;muhiddin bin ishak;mohamad aimanuddin bin mohtar;low teck yew. (2023). functional validation of crispr-cas9 genetic screening hit hsf4 in supporting clear cell renal cell carcinoma pathogenesis. - . .
ahmad rifqi bin md zain;tengku hasnan bin tengku abdul aziz;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar. (2023). optical sensor technique based on high quality factor suspended 1d photonic crystal (phc) structures for creatinine detection using non-invasive approach.. - . .
syazalina zahari , saiful effendi syafruddin , m. aiman mohtar. (2023). cancer cell secretome in driving breast cancer progression. - scholarly community encyclopedia. 1-8.
saiful effendi syafruddin, asmaa y. abuhamad, nurul nadia mohamad zamberi, siti nur hasanah mohd yusuf, m. aiman mohtar. (2023). cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma. - 6th international conference on molecular biology and biotechnology (icmbb). 1-15.
syazalina zahari, saiful effendi syafruddin, low teck yew, delphine fessart, tiannan guo, m. aiman mohtar. (2023). high throughput dia-nn proteomics identifies altered extracellular protein network in crispr- targeted agr2 of breast cancer cells. - 9th regional conference on molecular medicine (rcmm) in conjunction with 5th national conference for cancer research (nccr). 1-19.
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| ELUCIDATING THE RESISTANCE OF COLORECTAL (CRC) CANCER CELL LINES TO FOLFOX, A CHEMOTHERAPEUTIC AGENT WITH QUANTITATIVE PROTEOMICS AND UBIQUITOMICS | sciex | 93.7% (2021-07-01 sehingga 2024-06-28) |
| ELUCIDATING THE CROSSTALK BETWEEN HIF2α-VEGFA AND KLF6-PDGFβ AXES IN DRIVING RENAL CARCINOMA HYPERVASCULARIZATION | nanoarms sdn. bhd. | 27.7% (2023-10-01 sehingga 2025-09-30) |
| ELUCIDATING THE CROSSTALK BETWEEN HIF2α-VEGFA AND KLF6-PDGFβ AXES IN DRIVING RENAL CARCINOMA HYPERVASCULARIZATION | genomax technologies sdn bhd | 27.7% (2023-10-01 sehingga 2025-09-30) |
| COMB STRUCTURED WEARABLE METAMATERIAL WITH ELECTRICAL CONDUCTIVITY FOR HEALTH MONITORING GARMENT OF SEVERE PATIENTS | kelisa technology sdn bhd | 87.9% (2021-09-01 sehingga 2024-08-31) |
| ELUCIDATING THE FUNCTIONAL LINK BETWEEN PROXIMAL SUPER ENHANCER LOCUS AND NR3C1 TRANSCRIPTIONAL REGULATION IN CLEAR CELL RENAL CELL CARCINOMA. | next gene scientific sdn bhd | 94.2% (2021-03-01 sehingga 2024-06-30) |