Biografi/ Biography :
Dr. Hamizah Shahirah Hamezah is a research fellow at the Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM). She graduated from Universiti Kebangsaan Malaysia with Bachelor of Science in Genetics (Hons.) and Master in Medical Science (Biochemistry). She completed her Ph.D. in Medical Science at Molecular Neuroscience Research Center, Shiga University of Medical Science, Japan, under the supervision of Professor Dr. Ikuo Tooyama and Associate Professor Dr. Daijiro Yanagisawa. Upon completing her Ph.D., she was appointed as an Assistant Professor at the Department of Diagnostics and Therapeutics for Brain Diseases, Molecular Neuroscience Research Center, Shiga University of Medical Science, Japan. She has a great interest in understanding the mechanisms of learning and memory, as well as interventions for the cognitive decline during aging and neurodegenerative diseases. Her researches focus on finding possible biomarkers leading to the cognitive decline in brain aging and Alzheimer’s disease by using the state-of-art omics approaches, brain imaging, and cognitive neurosciences. She is also interested in finding possible therapeutics for the treatment of neurodegenerative diseases by investigating the effect of natural compounds on the transgenic animal models.
hamizah shahirah binti hamezah;syarul nataqain binti baharum;wan mohd aizat bin wan kamaruddin;ng chyan leong. (2024). elucidating the effect of mitragynine supplementation on brain proteome profiles, cognitive and locomotor functions of lipopolysaccharide-induced neuroinflammation in rats. - . .
chenyu zhou, quan xia, hamizah shahirah hamezah, zheng fan, xiaohui tong, rongchun han. (2024). efficacy of forsythia suspensa (thunb.) vahl on mouse and rat models of inflammation-related diseases: a meta-analysis. - frontiers in pharmacology. 1-11.
chenyu zhou, lanmeng yan, jing xu, hamizah shahirah hamezah, tongsheng wang, fangping du, xiaohui tong, rongchun han. (2024). phillyrin: an adipose triglyceride lipase inhibitor supported by molecular docking, dynamics simulation, and pharmacological validation. - journal of molecular modeling. 1-10.
hamizah shahirah hamezah, ummi kalthum azlan, ahmed mediani. (2024). effect of moringa oleifera leaves extract on cognitive function in lipopolysaccharide (lps)-induced rats. - international symposium on science and technology ukm-psu 2024 (isstup2024). 10.
nur aisyah khairul annuar, ummi kalthum azlan, ahmed mediani, xiaohui tong, rongchun han, ebtesam al-olayan, syarul nataqain baharum, hamidun bunawan, murni nazira sarian, hamizah shahirah hamezah, ibrahim jantan. (2024). an insight review on the neuropharmacological effects, mechanisms of action, pharmacokinetics and toxicity of mitragynine. - biomedicine & pharmacotherapy. 1-16.
chenyu zhou, quan xia, hamizah shahirah hamezah, zheng fan, xiaohui tong, rongchun han. (2024). efficacy of forsythia suspensa (thunb.) vahl on mouse and rat models of inflammation-related diseases: a meta-analysis. - frontiers in pharmacology. 1-11.
nur aisyah khairul annuar, ummi kalthum azlan, ahmed mediani, xiaohui tong, rongchun han, ebtesam al-olayan, syarul nataqain baharum, hamidun bunawan, murni nazira sarian, hamizah shahirah hamezah, ibrahim jantan. (2024). an insight review on the neuropharmacological effects, mechanisms of action, pharmacokinetics and toxicity of mitragynine. - biomedicine & pharmacotherapy. 1-16.
ummi kalthum azlan, nur aisyah khairul annuar, ahmed mediani, wan mohd aizat, hanafi ahmad damanhuri, xiaohui tong, daijiro yanagisawa, ikuo tooyama, wan zurinah wan ngah, ibrahim jantan, hamizah shahirah hamezah. (2023). an insight into the neuroprotective and anti-neuroinflammatory effects and mechanisms of moringa oleifera. - frontiers in pharmacology. 1-18.
siti norliyana zubaidi, wasim s. m. qadi, syahida maarof, norazlan mohmad misnan, halimatul saadiah mohammad noor, hamizah shahirah hamezah, syarul nataqain baharum, nurwahyuna rosli, faidruz azura jam, ebtesam al-olayan, chu. (2023). assessing the acute toxicological effects of annona muricata leaf ethanol extract on rats: biochemical, histopathological, and metabolomics analyses. - toxics. 1-20.
nor hafiza sayuti, nabilah zulkefli, jen kit tan, norazalina saad, syarul nataqain baharum, hamizah shahirah hamezah, hamidun bunawan, qamar uddin ahmed, humaira parveen, sayeed mukhtar, meshari a. alsharif, murni nazira sarian. (2023). ethanolic extract of polygonum minus protects differentiated human neuroblastoma cells (sh-sy5y) against h2o2-induced oxidative stress. - molecules. 1-24.
chenyu zhou, lanmeng yan, jing xu, hamizah shahirah hamezah, tongsheng wang, fangping du, xiaohui tong, rongchun han. (2024). phillyrin: an adipose triglyceride lipase inhibitor supported by molecular docking, dynamics simulation, and pharmacological validation. - journal of molecular modeling. 1-10.
chenyu zhou, quan xia, hamizah shahirah hamezah, zheng fan, xiaohui tong, rongchun han. (2024). efficacy of forsythia suspensa (thunb.) vahl on mouse and rat models of inflammation-related diseases: a meta-analysis. - frontiers in pharmacology. 1-11.
chenyu zhou, lanmeng yan, jing xu, hamizah shahirah hamezah, tongsheng wang, fangping du, xiaohui tong, rongchun han. (2024). phillyrin: an adipose triglyceride lipase inhibitor supported by molecular docking, dynamics simulation, and pharmacological validation. - journal of molecular modeling. 1-10.
nur aisyah khairul annuar, ummi kalthum azlan, ahmed mediani, xiaohui tong, rongchun han, ebtesam al-olayan, syarul nataqain baharum, hamidun bunawan, murni nazira sarian, hamizah shahirah hamezah, ibrahim jantan. (2024). an insight review on the neuropharmacological effects, mechanisms of action, pharmacokinetics and toxicity of mitragynine. - biomedicine & pharmacotherapy. 1-16.
ummi kalthum azlan, nur aisyah khairul annuar, ahmed mediani, wan mohd aizat, hanafi ahmad damanhuri, xiaohui tong, daijiro yanagisawa, ikuo tooyama, wan zurinah wan ngah, ibrahim jantan, hamizah shahirah hamezah. (2023). an insight into the neuroprotective and anti-neuroinflammatory effects and mechanisms of moringa oleifera. - frontiers in pharmacology. 1-18.
mohamed a. farag, farah elmetwally, rawan elghanam, nurkhalida kamal, khaoula hellal, hamizah shahirah hamezah, chao zhao, ahmed mediani. (2023). metabolomics in tea products; a compile of applications for enhancing agricultural traits and quality control analysis of camellia sinensis. - food chemistry. 1-16.
ahmed mediani, hamizah shahirah hamezah, emelda rosseleena rohani, nurkhalida kamal, vikneswari perumal, fatimah salim, ivana nur allisya rozlan, khaoula hellal, syed mahmood, nabil ali al-mekhlafi. (2023). handbook of dietary flavonoids. - . 1980.
hamizah shahirah binti hamezah;syarul nataqain binti baharum;wan mohd aizat bin wan kamaruddin;ng chyan leong. (2024). elucidating the effect of mitragynine supplementation on brain proteome profiles, cognitive and locomotor functions of lipopolysaccharide-induced neuroinflammation in rats. - . .
hamizah shahirah hamezah, ummi kalthum azlan, ahmed mediani. (2024). effect of moringa oleifera leaves extract on cognitive function in lipopolysaccharide (lps)-induced rats. - international symposium on science and technology ukm-psu 2024 (isstup2024). 10.
hamizah shahirah hamezah, lina wati durani, nor faeizah ibrahim, daijiro yanagisawa, hanafi ahmad damanhuri, wan zurinah wan ngah, ikuo tooyama. (2023). effects of tocotrienol rich fraction extracted from palm oil on brain proteome profiles in alzheimers disease mouse model. - 5th international conference on biosciences and medical engineering (icbme 2023). 1-2.
hamizah shahirah hamezah, lina wati durani, nor faeizah ibrahim, daijiro yanagisawa, hanafi ahmad damanhuri, wan zurinah wan ngah, ikuo tooyama. (2023). cognitive performance and age-related alterations in the brain proteome profiles. - international conference on natural products 2023 (icnp 2023). 1.
hamizah shahirah hamezah, daijiro yanagisawa, lina wati durani, nor faeizah ibrahim, hanafi ahmad damanhuri, wan zurinah wan ngah, ikuo tooyama. (2023). modulation of vitamin e tocotrienol-rich fraction on brain proteome profiles in specific brain regions of app/ps1 mice. - second moscow international conference on multi-omics technologies for precision medicine. 1.
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| DEVELOPMENT OF CHITOSAN NANOPARTICLES LOADED WITH POLYPHENOL-RICH LEAF EXTRACT OF ANACARDIUM OCCIDENTALE TO PROMOTE WOUND HEALING AND REGENERATION | dr. ridz skinlabs sdn bhd | 88.5% (2024-01-12 sehingga 2025-07-11) |
| DECIPHERING ANTIDIABETIC EFFECT AND MOLECULAR MECHANISM OF NEPTUNIA OLERACEA PHENOLICS RICH FRACTIONS LOADED IN NANOPARTICLES USING NMR- AND MS-BASED METABOLOMICS. | estika research centre (erc) | 80.3% (2023-10-01 sehingga 2025-09-30) |
| NEUROPROTECTIVE EFFECT OF A CHOCOLATE FORMULATION CONTAINING POLYPHENOL-RICH EXTRACTS OF COCOA AND MORINGA OLEIFERA AGAINST H2O2-INDUCED NEUROTOXICITY IN HUMAN NEUROBLASTOMA SH-SY5Y CELLS | lembaga koko malaysia | 23.6% (2025-02-12 sehingga 2026-02-11) |