Biografi/ Biography :
Dr. Hamizah Shahirah Hamezah is a research fellow at the Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM). She graduated from Universiti Kebangsaan Malaysia with Bachelor of Science in Genetics (Hons.) and Master in Medical Science (Biochemistry). She completed her Ph.D. in Medical Science at Molecular Neuroscience Research Center, Shiga University of Medical Science, Japan, under the supervision of Professor Dr. Ikuo Tooyama and Associate Professor Dr. Daijiro Yanagisawa. Upon completing her Ph.D., she was appointed as an Assistant Professor at the Department of Diagnostics and Therapeutics for Brain Diseases, Molecular Neuroscience Research Center, Shiga University of Medical Science, Japan. She has a great interest in understanding the mechanisms of learning and memory, as well as interventions for the cognitive decline during aging and neurodegenerative diseases. Her researches focus on finding possible biomarkers leading to the cognitive decline in brain aging and Alzheimer’s disease by using the state-of-art omics approaches, brain imaging, and cognitive neurosciences. She is also interested in finding possible therapeutics for the treatment of neurodegenerative diseases by investigating the effect of natural compounds on the transgenic animal models.
siti norliyana zubaidi, pei lou wong, wasim s.m. qadi, esraa adnan dawoud dawoud, hamizah shahirah hamezah, syarul nataqain baharum, faidruz azura jam, faridah abas, andres moreno, ahmed mediani. (2025). deciphering the mechanism of annona muricata leaf extract in alloxan-nicotinamide-induced diabetic rat model with 1h-nmr-based metabolomics approach. - journal of pharmaceutical and biomedical analysis. 1 - 15.
shasha sun, hamizah shahirah hamezah, chuanshan jin, rongchun han, xiaohui tong. (2025). albiflorin on neuropsychiatric and neurodegenerative disorders: a systematic review. - cns neuroscience & therapeutics. 1 - 13.
yuxin shan, hongjian shen, ling huang, hamizah shahirah hamezah, rongchun han, xia ren, chunhong zhang, xiaohui tong. (2025). optimized maxent analysis revealing the change of potential distribution area of lygodium japonicum in china driven by global warming. - frontiers in plant science. 1 - 13.
wasim s.m. qadi, nini tasnim fadzel, ahmed mediani, murni nazira sarian, xiaohui tong, rongchun han, faidruz azura jam, zulzikry hafiz abu bakar, hamizah shahirah hamezah. (2025). an insight review on the potential anti-hypertensive effects of moringa oleifera. - biomedicine & pharmacotherapy. 1 - 13.
zongran lu, ling huang, somnuk bunsupa, hamizah shahirah hamezah, xiaohui tong, chuanshan jin, jinmei ou, rongchun han. (2025). construction of a multi-omics database for paeonia lactiflora: a resource for comprehensive data integration and analysis. - bmc plant biology. 1 - 14.
siti norliyana zubaidi, pei lou wong, wasim s.m. qadi, esraa adnan dawoud dawoud, hamizah shahirah hamezah, syarul nataqain baharum, faidruz azura jam, faridah abas, andres moreno, ahmed mediani. (2025). deciphering the mechanism of annona muricata leaf extract in alloxan-nicotinamide-induced diabetic rat model with 1h-nmr-based metabolomics approach. - journal of pharmaceutical and biomedical analysis. 1 - 15.
shasha sun, hamizah shahirah hamezah, chuanshan jin, rongchun han, xiaohui tong. (2025). albiflorin on neuropsychiatric and neurodegenerative disorders: a systematic review. - cns neuroscience & therapeutics. 1 - 13.
yuxin shan, hongjian shen, ling huang, hamizah shahirah hamezah, rongchun han, xia ren, chunhong zhang, xiaohui tong. (2025). optimized maxent analysis revealing the change of potential distribution area of lygodium japonicum in china driven by global warming. - frontiers in plant science. 1 - 13.
wasim s.m. qadi, nini tasnim fadzel, ahmed mediani, murni nazira sarian, xiaohui tong, rongchun han, faidruz azura jam, zulzikry hafiz abu bakar, hamizah shahirah hamezah. (2025). an insight review on the potential anti-hypertensive effects of moringa oleifera. - biomedicine & pharmacotherapy. 1 - 13.
zongran lu, ling huang, somnuk bunsupa, hamizah shahirah hamezah, xiaohui tong, chuanshan jin, jinmei ou, rongchun han. (2025). construction of a multi-omics database for paeonia lactiflora: a resource for comprehensive data integration and analysis. - bmc plant biology. 1 - 14.
chenyu zhou, lanmeng yan, jing xu, hamizah shahirah hamezah, tongsheng wang, fangping du, xiaohui tong, rongchun han. (2024). phillyrin: an adipose triglyceride lipase inhibitor supported by molecular docking, dynamics simulation, and pharmacological validation. - journal of molecular modeling. 1-10.
shasha sun, hamizah shahirah hamezah, chuanshan jin, rongchun han, xiaohui tong. (2025). albiflorin on neuropsychiatric and neurodegenerative disorders: a systematic review. - cns neuroscience & therapeutics. 1 - 13.
yuxin shan, hongjian shen, ling huang, hamizah shahirah hamezah, rongchun han, xia ren, chunhong zhang, xiaohui tong. (2025). optimized maxent analysis revealing the change of potential distribution area of lygodium japonicum in china driven by global warming. - frontiers in plant science. 1 - 13.
wasim s.m. qadi, nini tasnim fadzel, ahmed mediani, murni nazira sarian, xiaohui tong, rongchun han, faidruz azura jam, zulzikry hafiz abu bakar, hamizah shahirah hamezah. (2025). an insight review on the potential anti-hypertensive effects of moringa oleifera. - biomedicine & pharmacotherapy. 1 - 13.
zongran lu, ling huang, somnuk bunsupa, hamizah shahirah hamezah, xiaohui tong, chuanshan jin, jinmei ou, rongchun han. (2025). construction of a multi-omics database for paeonia lactiflora: a resource for comprehensive data integration and analysis. - bmc plant biology. 1 - 14.
siti norliyana zubaidi, pei lou wong, wasim s.m. qadi, esraa adnan dawoud dawoud, hamizah shahirah hamezah, syarul nataqain baharum, faidruz azura jam, faridah abas, andres moreno, ahmed mediani. (2025). deciphering the mechanism of annona muricata leaf extract in alloxan-nicotinamide-induced diabetic rat model with 1h-nmr-based metabolomics approach. - journal of pharmaceutical and biomedical analysis. 1 - 15.
ahmed mediani, hamizah shahirah hamezah, emelda rosseleena rohani, nurkhalida kamal, vikneswari perumal, fatimah salim, ivana nur allisya rozlan, khaoula hellal, syed mahmood, nabil ali al-mekhlafi. (2023). afzelin: advances on resources, biosynthesis pathway, bioavailability, bioactivity, and pharmacology. - . 1-45.
hamizah shahirah hamezah, lina wati durani, nor faeizah ibrahim, daijiro yanagisawa, hanafi ahmad damanhuri, wan zurinah wan ngah, ikuo tooyama. (2024). proteome profiles in transgenic alzheimer’s disease mice brain and modulation by vitamin e tocotrienol-rich fraction. - biomedical chemistry: science and practice conference. .
hamizah shahirah binti hamezah;syarul nataqain binti baharum;wan mohd aizat bin wan kamaruddin;ng chyan leong. (2024). elucidating the effect of mitragynine supplementation on brain proteome profiles, cognitive and locomotor functions of lipopolysaccharide-induced neuroinflammation in rats. - . .
lah, n.h.c., azizan, k.a., misnan, n.m., mediani, a., hamezah, h.s., noor, n.m., rohani, e.r.. (2024). utilizing liquid chromatography tandem mass spectrometry (lc-ms/ms) for investigation of the recalcitrant behavior of desiccated seeds. - international symposium on synthetic biology and crispr technology (isynbioct 2024). .
hamizah shahirah hamezah. (2024). age-related alterations of brain proteome profiles in aging. - international meeting - 48th annual conference of the msbmb (im-msbmb48). .
hamizah shahirah hamezah, ummi kalthum azlan. (2024). modulation of moringa oleifera on neuroinflammation-induced cognitive impairment in rats. - international conference on natural products 2024 (icnp 2024). .
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| DECIPHERING ANTIDIABETIC EFFECT AND MOLECULAR MECHANISM OF NEPTUNIA OLERACEA PHENOLICS RICH FRACTIONS LOADED IN NANOPARTICLES USING NMR- AND MS-BASED METABOLOMICS. | estika research centre (erc) | 99.5% (2023-10-01 sehingga 2025-09-30) |
| DECIPHERING ANTIDIABETIC EFFECT AND MOLECULAR MECHANISM OF NEPTUNIA OLERACEA PHENOLICS RICH FRACTIONS LOADED IN NANOPARTICLES USING NMR- AND MS-BASED METABOLOMICS. | estika research centre (erc) | 99.5% (2023-10-01 sehingga 2025-09-30) |
| NEUROPROTECTIVE EFFECT OF A CHOCOLATE FORMULATION CONTAINING POLYPHENOL-RICH EXTRACTS OF COCOA AND MORINGA OLEIFERA AGAINST H2O2-INDUCED NEUROTOXICITY IN HUMAN NEUROBLASTOMA SH-SY5Y CELLS | lembaga koko malaysia | 62.1% (2025-02-12 sehingga 2026-02-11) |