Kluster Kepakaran/ Cluster of Expertise :
Sumber Lestari, Alam Sekitar dan Kehidupan Pintar,
Sumber Lestari, Alam Sekitar dan Kehidupan Pintar,
Biografi/ Biography :
Dr. Hamizah Shahirah Hamezah is a research fellow at the Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM). She graduated from Universiti Kebangsaan Malaysia with Bachelor of Science in Genetics (Hons.) and Master in Medical Science (Biochemistry). She completed her Ph.D. in Medical Science at Molecular Neuroscience Research Center, Shiga University of Medical Science, Japan, under the supervision of Professor Dr. Ikuo Tooyama and Associate Professor Dr. Daijiro Yanagisawa. Upon completing her Ph.D., she was appointed as an Assistant Professor at the Department of Diagnostics and Therapeutics for Brain Diseases, Molecular Neuroscience Research Center, Shiga University of Medical Science, Japan. She has a great interest in understanding the mechanisms of learning and memory, as well as interventions for the cognitive decline during aging and neurodegenerative diseases. Her researches focus on finding possible biomarkers leading to the cognitive decline in brain aging and Alzheimer’s disease by using the state-of-art omics approaches, brain imaging, and cognitive neurosciences. She is also interested in finding possible therapeutics for the treatment of neurodegenerative diseases by investigating the effect of natural compounds on the transgenic animal models.
syarul nataqain baharum, sameh abouzid, hayam ahmed, hamizah shahirah hamezah, habsah aziz, doaa a. ghareeb, sherine n. khattab, osama m. ahmed, wasim s. m. qadi, maya erna natnan, ibrahim jantan. (2026). recent advances in metabolomics approaches in identification of anti-inflammatory natural products for development of drugs to treat inflammation-associated disorders. - trends in analytical chemistry. 1 - 19.
rui guan, yuxin shan, hamizah shahirah hamezah, somnuk bunsupa, hong to quyen duong, yadong zhou, rongchun han, xiaohui tong. (2026). non-targeted metabolomic profiling of cremastra appendiculata providing insights for phytochemical analyses. - peerj. 1 - 19.
ummi kalthum azlan, hadi azamuddin abd hakim, pei lou wong, noor hanini che lah, chenyu zhou, nur irlia sofea mohammad zamani, xiaohui tong, rongchun han, norazlan mohmad misnan, murni nazira sarian, emelda rosseleena rohani, ahmed mediani, faidruz azura jam, hamizah shahirah hamezah. (2026). integrative metabolomics using untargeted uhplc-ms/ms and chemometrics identifies optimal maturity stage of moringa oleifera leaves from kuala terengganu, malaysia. - peerj. 1 - 28.
chenyu zhou, murni nazira sarian, xiaohui tong, rongchun han, theebaa anasamy, hamizah shahirah hamezah. (2026). halogenated anthraquinones in breast cancer therapy: structural modifications targeting vegf-related angiogenesis pathways. - journal of pharmaceutical analysis. 1 - 19.
zhanqing luo, muhammad zulfiqah sadikan, faidruz azura jam, rusdiah ruzanna jusoh, xiaohui tong, rongchun han, murni nazira sarian, ahmed mediani, hamizah shahirah hamezah. (2026). understanding diabetic retinopathy using multi-omics approaches: a narrative review. - sains malaysiana. 1009 - 1020.
syarul nataqain baharum, sameh abouzid, hayam ahmed, hamizah shahirah hamezah, habsah aziz, doaa a. ghareeb, sherine n. khattab, osama m. ahmed, wasim s. m. qadi, maya erna natnan, ibrahim jantan. (2026). recent advances in metabolomics approaches in identification of anti-inflammatory natural products for development of drugs to treat inflammation-associated disorders. - trends in analytical chemistry. 1 - 19.
rui guan, yuxin shan, hamizah shahirah hamezah, somnuk bunsupa, hong to quyen duong, yadong zhou, rongchun han, xiaohui tong. (2026). non-targeted metabolomic profiling of cremastra appendiculata providing insights for phytochemical analyses. - peerj. 1 - 19.
ummi kalthum azlan, hadi azamuddin abd hakim, pei lou wong, noor hanini che lah, chenyu zhou, nur irlia sofea mohammad zamani, xiaohui tong, rongchun han, norazlan mohmad misnan, murni nazira sarian, emelda rosseleena rohani, ahmed mediani, faidruz azura jam, hamizah shahirah hamezah. (2026). integrative metabolomics using untargeted uhplc-ms/ms and chemometrics identifies optimal maturity stage of moringa oleifera leaves from kuala terengganu, malaysia. - peerj. 1 - 28.
chenyu zhou, murni nazira sarian, xiaohui tong, rongchun han, theebaa anasamy, hamizah shahirah hamezah. (2026). halogenated anthraquinones in breast cancer therapy: structural modifications targeting vegf-related angiogenesis pathways. - journal of pharmaceutical analysis. 1 - 19.
djilali benabdelmoumene, muhammad waqar, abderahman shawky, omnia darwish askar, wasim s. m. qadi, said dahmouni, mariam gamaleldin, faidruz azura jam, ahmed mediani, hamizah shahirah hamezah, habsah aziz, sajad ali, soo yee lee. (2026). germination-driven biochemical remodeling of cereals and pseudocereals: impacts on nutrient bioaccessibility, phytochemical enrichment, and functional food potential. - food chemistry. 1 - 15.
zhanqing luo, muhammad zulfiqah sadikan, faidruz azura jam, rusdiah ruzanna jusoh, xiaohui tong, rongchun han, murni nazira sarian, ahmed mediani, hamizah shahirah hamezah. (2026). understanding diabetic retinopathy using multi-omics approaches: a narrative review. - sains malaysiana. 1009 - 1020.
noureddine benguennouna, djilali benabdelmoumene, said dahmouni, zineb bengharbi, wasim s.m. qadi, hamizah shahirah hamezah, ahmed mediani. (2025). eco-phytoremediation using azolla microphylla enhances heavy metal removal, water quality, and biomass valorization in semi-arid wastewater treatment. - desalination and water treatment. 1 - 11.
chenyu zhou, lanmeng yan, jing xu, hamizah shahirah hamezah, tongsheng wang, fangping du, xiaohui tong, rongchun han. (2024). phillyrin: an adipose triglyceride lipase inhibitor supported by molecular docking, dynamics simulation, and pharmacological validation. - journal of molecular modeling. 1-10.
syarul nataqain baharum, sameh abouzid, hayam ahmed, hamizah shahirah hamezah, habsah aziz, doaa a. ghareeb, sherine n. khattab, osama m. ahmed, wasim s. m. qadi, maya erna natnan, ibrahim jantan. (2026). recent advances in metabolomics approaches in identification of anti-inflammatory natural products for development of drugs to treat inflammation-associated disorders. - trends in analytical chemistry. 1 - 19.
rui guan, yuxin shan, hamizah shahirah hamezah, somnuk bunsupa, hong to quyen duong, yadong zhou, rongchun han, xiaohui tong. (2026). non-targeted metabolomic profiling of cremastra appendiculata providing insights for phytochemical analyses. - peerj. 1 - 19.
ummi kalthum azlan, hadi azamuddin abd hakim, pei lou wong, noor hanini che lah, chenyu zhou, nur irlia sofea mohammad zamani, xiaohui tong, rongchun han, norazlan mohmad misnan, murni nazira sarian, emelda rosseleena rohani, ahmed mediani, faidruz azura jam, hamizah shahirah hamezah. (2026). integrative metabolomics using untargeted uhplc-ms/ms and chemometrics identifies optimal maturity stage of moringa oleifera leaves from kuala terengganu, malaysia. - peerj. 1 - 28.
chenyu zhou, murni nazira sarian, xiaohui tong, rongchun han, theebaa anasamy, hamizah shahirah hamezah. (2026). halogenated anthraquinones in breast cancer therapy: structural modifications targeting vegf-related angiogenesis pathways. - journal of pharmaceutical analysis. 1 - 19.
zhanqing luo, muhammad zulfiqah sadikan, faidruz azura jam, rusdiah ruzanna jusoh, xiaohui tong, rongchun han, murni nazira sarian, ahmed mediani, hamizah shahirah hamezah. (2026). understanding diabetic retinopathy using multi-omics approaches: a narrative review. - sains malaysiana. 1009 - 1020.
ahmed mediani, jalifah latip, fatimah salim, syed mahmood, ayah rebhi hilles, mohd asraf mohd zainudin, nurkhalida kamal, nurul syahidah mio asni, hamizah shahirah hamezah, amatul hamizah ali, khaoula hellal, vikneswari perumal, siti norliyana zubaidi, nabil ali al-mekhlafi, norzila ismail . (2025). vitexin: advances on resources, biosynthesis pathway, bioavailability, bioactivity, and pharmacology. - . 1 - 63.
ahmed mediani, hamizah shahirah hamezah, emelda rosseleena rohani, nurkhalida kamal, vikneswari perumal, fatimah salim, ivana nur allisya rozlan, khaoula hellal, syed mahmood, nabil ali al-mekhlafi. (2023). afzelin: advances on resources, biosynthesis pathway, bioavailability, bioactivity, and pharmacology. - . 1-45.
lah, n.h.c., azizan, k.a., misnan, n.m., hamezah, h.s., noor, n.m. and rohani, e.r.. (2025). exploring the desiccation sensitivity of mangosteen seeds through metabolomic analysis. - malaysian society of plant physiology (mspp). .
noor hanini che lah, norazlan mohmad misnan, kamalrul azlan azizan, ahmed mediani, hamizah shahirah hamezah, rongchun han, mohd razik midin, normah mohd noor, emelda rosseleena rohani. (2025). metabolite profiling of desiccation response in recalcitrant mangosteen (garcinia mangostana) seeds. - asian regional conference on systems biology (arcsb2025) x international conference on natural products (icnp2025). .
lah, n.h.c., azizan, k.a., misnan, n.m., mediani, a., hamezah, h.s., noor, n.m., rohani, e.r.. (2025). metabolic investigation of mangosteen seed viability decodes recalcitrant behaviour. - natural products and health — 2025 graduate international forum. .
hamizah shahirah binti hamezah;syarul nataqain binti baharum;wan mohd aizat bin wan kamaruddin;ng chyan leong. (2024). elucidating the effect of mitragynine supplementation on brain proteome profiles, cognitive and locomotor functions of lipopolysaccharide-induced neuroinflammation in rats. - . .
lah, n.h.c., azizan, k.a., misnan, n.m., mediani, a., hamezah, h.s., noor, n.m., rohani, e.r.. (2024). utilizing liquid chromatography tandem mass spectrometry (lc-ms/ms) for investigation of the recalcitrant behavior of desiccated seeds. - international symposium on synthetic biology and crispr technology (isynbioct 2024). .
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| MOLECULAR INVESTIGATIONS OF GOITROGENIC COMPOUNDS | comsats university islamabad | 76.4% (2025-10-01 sehingga 2026-09-30) |
BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
PROTEOMICS AND MOLECULAR NEUROSCIENCE
Pengalaman / Experience : 6 tahun/years(s)