Biografi/ Biography :
Dr. Isma has joined the Department of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM) in 2021. She graduated Bachelor of Biomedical Sciences (Honours) from UKM in 2006 and then worked in the Ministry of Health, Malaysia (2008-2013). She was conferred a PhD (Anatomy) from the National University of Ireland (NUI), Galway, in 2017. She did her post-doctorate research in SFI Research Centre for Medical Devices (CÚRAM), NUI Galway (2017-2020), and the Department of Orthopaedics and Traumatology UKM (2021). Dr Isma has expertise in intervertebral disc and biomaterial research. Her work focuses on degenerative disc disease, specifically to modulate inflammatory pain, extracellular matrix regulation, disc microstructure, and molecular, proteome and glycome profiling in disc degeneration using a biomaterial approach. Dr Isma has been involved in disease modelling to establish a pre-clinical model of pain induced by disc injury. She is also developing a bioengineered hydrogel to support stem cell transplantation for disc regeneration targeting inflammatory pain. She plans to advance her research towards patient-specific regenerative therapy using precision medicine and biomaterial-based tissue engineering. Her major achievements include the patent filed of the technology to promote disc regeneration targeting pain and the recipient of prestigious awards, including the Emerging Investigator Award for Health from the Health Research Board, Ireland, Outstanding Anatomist Award (Research) by the Malaysian Anatomical Association, Julia Polak European Doctorate Award from the European Society for Biomaterials and First Prize Young Researcher Award from AO Spine. She has authored/co-authored numerous publications in high-impact journals, including Science Advances, PNAS, Biomaterials, and Advanced Science. Dr Isma is also a reviewer for peer-reviewed journals and actively presented her work at tier-one international conferences, including the World Biomaterials Congress, the World Forum for Spine Research, and
noraziah nordin, marjanu hikmah elias, nuruliza roslan, fariha mohd manzor, khairi abdul rahim, nazefah abdul hamid, isma liza mohd isa, faizul helmi addnan. (2024). patience humility devotion the odyssey for knowledge. - . 200.
asrizal abdul rahman, isma liza mohd isa, syed a. m. tofail, lukasz bartlomiej, brian j. rodriguez, manus j. biggs, and abhay pandit. (2024). modification of living diatom, thalassiosira weissflogii, with a calcium precursor through a calcium uptake mechanism: a next generation biomaterial for advanced delivery systems. - acs applied bio materials. 4102-4115.
isma liza mohd isa, syafira masri, loai a. elfawy, safa tahri, ibrahim n. amirrah, revatyambigai subramaniam, raed h. ogai, wan chiew ng, nur amalia ra'oh, mh. busra fauzi, akshay srivastava, sabarul afian mokhtar. (2024). drug delivery systems for musculoskeletal tissues. - . 41.
isma liza mohd isa, seong lin teoh, nurul huda mohd nor, sabarul afian mokhtar. (2023). discogenic low back pain: anatomy, pathophysiology and treatments of intervertebral disc degeneration. - international journal of molecular sciences. 1-16.
niranjan g. kotla, isma liza mohd isa, aitor larrañaga, balaji maddiboyina, samantha k. swamy, gandhi sivaraman, and praveen k. vemula. (2023). hyaluronic acid-based bioconjugate systems, scaffolds, and their therapeutic potential. - advanced healthcare materials. 1-26.
isma liza mohd isa, izzat zulkiflee, raed h. ogaili, nurul huda mohd yusoff, natasya nadia sahruddin, shaiful ridzwan sapri, elvy suhana mohd ramli,mh busra fauzi and sabarul afian mokhtar. (2023). three-dimensional hydrogel with human wharton jelly-derived mesenchymal stem cells towards nucleus pulposus niche. - frontiers in bioengineering and biotechnology. 1-9.
niranjan g. kotla, isma liza mohd isa, aitor larrañaga, balaji maddiboyina, samantha k. swamy, gandhi sivaraman, and praveen k. vemula. (2023). hyaluronic acid-based bioconjugate systems, scaffolds, and their therapeutic potential. - advanced healthcare materials. 1-26.
isma liza mohd isa, seong lin teoh, nurul huda mohd nor, sabarul afian mokhtar. (2023). discogenic low back pain: anatomy, pathophysiology and treatments of intervertebral disc degeneration. - international journal of molecular sciences. 1-16.
isma liza mohd isa, sabarul afian mokhtar, sunny a. abbah, mh busra fauzi, aiden devitt, and abhay pandit. (2022). intervertebral disc degeneration: biomaterials and tissue engineering strategies toward precision medicine. - advanced healthcare materials. 1-29.
nur izzah md fadilah, isma liza mohd isa , wan safwani wan kamarul zaman, yasuhiko tabata and mh busra fauzi. (2022). the effect of nanoparticle-incorporated natural-based biomaterials towards cells on activated pathways: a systematic review. - polymers. 1-22.
asrizal abdul rahman, isma liza mohd isa, syed a. m. tofail, lukasz bartlomiej, brian j. rodriguez, manus j. biggs, and abhay pandit. (2024). modification of living diatom, thalassiosira weissflogii, with a calcium precursor through a calcium uptake mechanism: a next generation biomaterial for advanced delivery systems. - acs applied bio materials. 4102-4115.
isma liza mohd isa, izzat zulkiflee, raed h. ogaili, nurul huda mohd yusoff, natasya nadia sahruddin, shaiful ridzwan sapri, elvy suhana mohd ramli,mh busra fauzi and sabarul afian mokhtar. (2023). three-dimensional hydrogel with human wharton jelly-derived mesenchymal stem cells towards nucleus pulposus niche. - frontiers in bioengineering and biotechnology. 1-9.
niranjan g. kotla, isma liza mohd isa, aitor larrañaga, balaji maddiboyina, samantha k. swamy, gandhi sivaraman, and praveen k. vemula. (2023). hyaluronic acid-based bioconjugate systems, scaffolds, and their therapeutic potential. - advanced healthcare materials. 1-26.
isma liza mohd isa, seong lin teoh, nurul huda mohd nor, sabarul afian mokhtar. (2023). discogenic low back pain: anatomy, pathophysiology and treatments of intervertebral disc degeneration. - international journal of molecular sciences. 1-16.
nur izzah md fadilah, isma liza mohd isa , wan safwani wan kamarul zaman, yasuhiko tabata and mh busra fauzi. (2022). the effect of nanoparticle-incorporated natural-based biomaterials towards cells on activated pathways: a systematic review. - polymers. 1-22.
isma liza mohd isa, syafira masri, loai a. elfawy, safa tahri, ibrahim n. amirrah, revatyambigai subramaniam, raed h. ogai, wan chiew ng, nur amalia ra'oh, mh. busra fauzi, akshay srivastava, sabarul afian mokhtar. (2024). drug delivery systems for musculoskeletal tissues. - . 41.
mh busra fauzi, samantha lo, maheswary thambirajoo, zawani mazlan, izzat zulkiflee, syafira masri, isma liza mohd isa and sabarul afian mokhtar. (2023). advances in biomedical polymers and composites - materials and applications. - . 34.
isma liza mohd isa, syafira masri, loai a. elfawy, safa tahri, ibrahim n. amirrah, revatyambigai subramaniam, raed h. ogai, wan chiew ng, nur amalia ra'oh, mh. busra fauzi, akshay srivastava, sabarul afian mokhtar. (2024). drug delivery systems for musculoskeletal tissues. - . 41.
mh busra fauzi, samantha lo, maheswary thambirajoo, zawani mazlan, izzat zulkiflee, syafira masri, isma liza mohd isa and sabarul afian mokhtar. (2023). advances in biomedical polymers and composites - materials and applications. - . 34.
noraziah nordin, marjanu hikmah elias, nuruliza roslan, fariha mohd manzor, khairi abdul rahim, nazefah abdul hamid, isma liza mohd isa, faizul helmi addnan. (2024). patience humility devotion the odyssey for knowledge. - . 200.
isma liza mohd isa. (2023). celebrating the success of dr isma liza mohd isa for international women's day. - . NA.
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| DISC-ON-A-CHIP FOR THE MODELLING OF PATIENT-SPECIFIC PATHOGENESIS OF INTERVERTEBRAL DISC DEGENERATION UNDERLYING INFLAMMATORY PAIN | national university of ireland, galway | 64% (2023-06-08 sehingga 2026-06-07) |
| BIOCOMPATIBILITY AND IMMUNO-MODULATORY EFFECT OF THE HYALURONIC ACID/COLLAGEN-BASED HYDROGEL FOR INTERVERTEBRAL DISC REGENERATION | makmal bioserasi, crim, ukm | 94.8% (2022-10-01 sehingga 2025-06-30) |