ts. dr. saiful effendi bin syafruddin

pensyarah universiti

institut biologi molekul perubatan ukm (umbi)

 effendisy@ppukm.ukm.edu.my



   Biografi/ Biography :


  • Saiful Effendi Syafruddin is a Research Fellow/Senior Lecturer at the UKM Medical Molecular Biology Institute (UMBI). He holds PhD in Medical Sciences from the University of Cambridge, UK. He previously earned his Master’s in Biotechnology (Molecular Genetic) from the University of Pennsylvania, USA, and BSc. in Biotechnology from Rochester Institute of Technology, USA. His PhD project focused on elucidating the genetic and epigenetic determinants that support kidney cancer pathogenesis. Saiful Effendi research interest revolves around understanding cancer molecular dependencies, specifically in kidney cancer, with the aim to identify novel and efficient clinical strategies to fight against cancer. Having been trained in the field of cell and molecular biology, cancer biology and genetic engineering for more than a decade, he has been extensively utilizing various state-of-the-art laboratory techniques throughout his cancer research works. Several of his research works have been published in high impact journals such as Nature, Cancer Discovery, Nature Communication, and Cell.

  • poh kuan wong, norazrina azmi, saiful effendi syafruddin, fook choe cheah, eng wee chua.  (2024).  rna sequencing reveals transcriptomic changes in hek293 cells following introduction of rs16851030 dna variant.  - malaysian journal of medicine and health sciences.  49. 

     

    siti nur hasanah mohd yusuf, m. aiman mohtar, saiful effendi syafruddin.  (2023).  penyahkawalseliaan proses transkripsi dalam patogenesis kanser.  - majalah dewan kosmik.  50-53. 

     

    nurul nadia binti mohamad zamberi, mohamad aimanuddin mohtar, saiful effendi syafruddin.  (2023).  mef2c transactivates the expression of growth-promoting klf6 in renal carcinoma.  - 6th international conference on molecular biology and biotechnology 2023 (icmbb2023).  1-15. 

     

    marjanu hikmah elias, nurunnajah lazim, zulazmi sutaji, mohammad azrai abu, abdul kadir abdul karim, azizah ugusman, saiful effendi syafruddin, mohd helmy mokhtar, mohd faizal ahmad.  (2023).  hoxa10 dna methylation level in the endometrium women with endometriosis: a systematic review.  - biology.  1-11. 

     

    nur syakirah othman, amilia aminuddin, shahidee zainal abidin, saiful effendi syafruddin, mohd faizal ahmad, norfilza mohd mokhtar, jaya kumar, adila a. hamid, azizah ugusman.  (2023).  profiling of differentially expressed micrornas in human umbilical vein endothelial cells exposed to hyperglycemia via rna sequencing.  - life.  1-16. 

     

    m. aiman mohtar, syazalina zahari, nisa syakila a. rahman, saiful effendi, muhammad-redha abdullah-zawawi, teck yew low, ted hupp.  (2023).  rna-seq analysis of crispr-cas9 targeted agr2 of breast cancer cells reveals potential modulators of its expression and secretion.  - esmo open.  6. 

     

    marjanu hikmah elias, nurunnajah lazim, zulazmi sutaji, mohammad azrai abu, abdul kadir abdul karim, azizah ugusman, saiful effendi syafruddin, mohd helmy mokhtar, mohd faizal ahmad.  (2023).  hoxa10 dna methylation level in the endometrium women with endometriosis: a systematic review.  - biology.  1-11. 

     

    nur syakirah othman, amilia aminuddin, shahidee zainal abidin, saiful effendi syafruddin, mohd faizal ahmad, norfilza mohd mokhtar, jaya kumar, adila a. hamid, azizah ugusman.  (2023).  profiling of differentially expressed micrornas in human umbilical vein endothelial cells exposed to hyperglycemia via rna sequencing.  - life.  1-16. 

     

    mohd faizal ahmad, marjanu hikmah elias, norazilah mat jin, muhammad azrai abu, saiful effendi syafruddin, ani amelia zainuddin, nao suzuki, abdul kadir abdul karim.  (2023).  the spectrum of in vitro maturation in clinical practice: the current insight.  - frontiers in endocrinology.  1-13. 

     

    poh kuan wong, nurul nadia mohamad zamberi, saiful effendi syafruddin, fook choe cheah, norazrina azmi, jia xian law, eng wee chua.  (2023).  the promises and pitfalls of crispr-mediated base editing in stem cells.  - crispr journal.  196-215. 

     

    saiful effendi syafruddin, wan fahmi wan mohamad nazarie, nurshahirah ashikin moidu, bee hong soon, m. aiman mohtar.  (2021).  integration of rna-seq and proteomics data identifies glioblastoma multiforme surfaceome signature.  - bmc cancer.  1-13. 

     

    nur fadhlina mohamad pakarulrazy, saiful effendi syafruddin, nurul syakima ab mutalib, azlina ahmad annuar, shen yang lim, rahman jamal, nor azian abdul murad, norlinah mohamed ibrahim.  (2020).  glucocerebrosidase genetic variants in malays with early and late-onset parkinson's disease.  - neurology asia.  39-46. 

     

    poh kuan wong, norazrina azmi, saiful effendi syafruddin, fook choe cheah, eng wee chua.  (2024).  rna sequencing reveals transcriptomic changes in hek293 cells following introduction of rs16851030 dna variant.  - malaysian journal of medicine and health sciences.  49. 

     

    marjanu hikmah elias, nurunnajah lazim, zulazmi sutaji, mohammad azrai abu, abdul kadir abdul karim, azizah ugusman, saiful effendi syafruddin, mohd helmy mokhtar, mohd faizal ahmad.  (2023).  hoxa10 dna methylation level in the endometrium women with endometriosis: a systematic review.  - biology.  1-11. 

     

    nur syakirah othman, amilia aminuddin, shahidee zainal abidin, saiful effendi syafruddin, mohd faizal ahmad, norfilza mohd mokhtar, jaya kumar, adila a. hamid, azizah ugusman.  (2023).  profiling of differentially expressed micrornas in human umbilical vein endothelial cells exposed to hyperglycemia via rna sequencing.  - life.  1-16. 

     

    mohd faizal ahmad, marjanu hikmah elias, norazilah mat jin, muhammad azrai abu, saiful effendi syafruddin, ani amelia zainuddin, nao suzuki, abdul kadir abdul karim.  (2023).  the spectrum of in vitro maturation in clinical practice: the current insight.  - frontiers in endocrinology.  1-13. 

     

    lazim nurunnajah, elias marjanu hikmah, syafruddin saiful effendi, sutaji zulazmi, abu mohammad azrai, abdul karim abdul kadir, ugusman azizah, mokhtar mohd helmy, ahmad mohd faizal.  (2023).  expression of hoxa10 in endometriotic women following modulation of gonadotropin-releasing hormone receptor.  - medical journal of malaysia.  84. 

     

    aminah suhaila haron, saiful e. syafruddin, ilie fadzilah hashim, muggunna balasubramaniam, saw keat chuan, yasmin hasnizan, nurul syafawani fizal, chong chien fung, ana masara ahmad mokhtar.  (2023).  genetic disorders and rare diseases current updates.  - 16. 

     

    saiful effendi syafruddin, mohamad aimanuddin mohtar, tan shing cheng, nadiah abu, nor aidatulakma abdullah@muda, nurul syakima ab mutalib, chin siok fong, neoh hui min, rahman jamal, nor azian abdul murad.  (2019).  malaysian higher institution centres of excellence (hicoe) official compendium.  - 244. 

     

    ahmad rifqi bin md zain;tengku hasnan bin tengku abdul aziz;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar.  (2023).  optical sensor technique based on high quality factor suspended 1d photonic crystal (phc) structures for creatinine detection using non-invasive approach..  -

     

    yuh cai chia, sundharavalli ramayah , nurul nadia mohamad zamberi, mohamad aimanuddin mohtar , saiful effendi syafruddin.  (2023).  crispr/cas9: teknik penyuntingan dan modifikasi gen.  - 1. 

     

    syazalina zahari, saiful effendi syafruddin, low teck yew, delphine fessart, tiannan guo, m. aiman mohtar.  (2023).  high throughput dia-nn proteomics identifies altered extracellular protein network in crispr- targeted agr2 of breast cancer cells.  - 9th regional conference on molecular medicine (rcmm) in conjunction with 5th national conference for cancer research (nccr).  1-19. 

     

    saiful effendi syafruddin, nurul nadia mohamad zamberi, asmaa y. abuhamad. sarah izzati izzat azrai, mohd khairul nizam mohd khalid , m. aiman mohtar.  (2023).  super enhancer-associated glucocorticoid receptor nr3c1 supports renal carcinoma growth by transcriptionally regulating the expression of pdk4, edn2 and il-6.  - 15th malaysia international genetics congress 2023.  1-19. 

     

    nurul nadia mohamad zamberi, jie sheng aik, zulkifli bin md. zainuddin, m. aiman mohtar, saiful effendi syafruddin..  (2023).  super enhancer upstream regulators drive klf6-pdgfb expression and mtorc1 pathway activation in renal carcinoma.  - 9th regional conference on molecular medicine (rcmm) in conjunction with 5th national conference for cancer research (nccr).  1-22.