dr. saiful effendi bin syafruddin

pensyarah universiti

institut biologi molekul perubatan ukm (umbi)

 effendisy@ppukm.ukm.edu.my

No. Telefon Rasmi :  0391459072

No. rasmi:
UKM : 03 8921 5555



   Biografi/ Biography :


  • Saiful Effendi Syafruddin is a Research Fellow/Senior Lecturer at the UKM Medical Molecular Biology Institute (UMBI). He holds PhD in Medical Sciences from the University of Cambridge, UK. He previously earned his Master’s in Biotechnology (Molecular Genetic) from the University of Pennsylvania, USA, and BSc. in Biotechnology from Rochester Institute of Technology, USA. His PhD project focused on elucidating the genetic and epigenetic determinants that support kidney cancer pathogenesis. Saiful Effendi research interest revolves around understanding cancer molecular dependencies, specifically in kidney cancer, with the aim to identify novel and efficient clinical strategies to fight against cancer. Having been trained in the field of cell and molecular biology, cancer biology and genetic engineering for more than a decade, he has been extensively utilizing various state-of-the-art laboratory techniques throughout his cancer research works. Several of his research works have been published in high impact journals such as Nature, Cancer Discovery, Nature Communication, and Cell.

  • saiful effendi syafruddin.  (2022).  cellular and molecular biology of cancer: insights for early detection and therapeutics.  - 1-27. 

     

    low teck yew;mohd firdaus bin mohd raih;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar;lee pey yee.  (2022).  elucidating the mechanism of secretion for human pro-metastatic agr2 protein.  -

     

    nurainie sayutti, muhammad azrai abu, saiful effendi, mohd faizal ahmad.  (2022).  elucidating the gene expression of grem 1 in cumulus cells and its association with oocytes quality in predicting pregnancy outcomes among pcos women.  - gynecological endocrinology the 20th world congress.  1. 

     

    alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low.  (2022).  short open reading frames (sorfs) and microproteins: an update on their identification and validation measures.  - journal of biomedical science.  1-15. 

     

    saroor a. patel, shoko hirosue, paulo rodrigues, erika vojtasova, emma k. richardson, jianfeng ge, saiful e. syafruddin, alyson speed, evangelia k. papachristou, david baker, david clarke, ludovic wesolowski, , jason s. carroll, sakari vanharanta.  (2022).  the renal lineage factor pax8 controls oncogenic signalling in kidney cancer.  - nature.  999-1006. 

     

    alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low.  (2022).  short open reading frames (sorfs) and microproteins: an update on their identification and validation measures.  - journal of biomedical science.  1-15. 

     

    rashidah baharudin, muhiddin ishak, azliana muhamad yusof, sazuita saidin, saiful effendi syafruddin, wan fahmi wan mohamad nazarie, learn-han lee, nurul-syakima ab mutalib.  (2022).  epigenome-wide dna methylation profiling in colorectal cancer and normal adjacent colon using infinium human methylation 450k.  - diagnostics.  1-22. 

     

    nisa syakila a. rahman, syazalina zahari, saiful effendi syafruddin, mohd firdaus-raih, teck yew low, m. aiman mohtar.  (2022).  functions and mechanisms of protein disulfide isomerase family in cancer emergence.  - cell & bioscience.  1-19. 

     

    asmaa y. abuhamad, nurul nadia mohamad zamberi, ling sheen, safaa m. naes, siti nur hasanah mohd yusuf, asilah ahmad tajudin, m. aiman mohtar, amir syahir amir hamzah, saiful effendi syafruddin.  (2022).  reverting tp53 mutation in breast cancer cells: prime editing workflow and technical considerations.  - cells.  1-16. 

     

    saroor a. patel, shoko hirosue, paulo rodrigues, erika vojtasova, emma k. richardson, jianfeng ge, saiful e. syafruddin, alyson speed, evangelia k. papachristou, david baker, david clarke, ludovic wesolowski, , jason s. carroll, sakari vanharanta.  (2022).  the renal lineage factor pax8 controls oncogenic signalling in kidney cancer.  - nature.  999-1006. 

     

    saiful effendi syafruddin, wan fahmi wan mohamad nazarie, nurshahirah ashikin moidu, bee hong soon, m. aiman mohtar.  (2021).  integration of rna-seq and proteomics data identifies glioblastoma multiforme surfaceome signature.  - bmc cancer.  1-13. 

     

    nur fadhlina mohamad pakarulrazy, saiful effendi syafruddin, nurul syakima ab mutalib, azlina ahmad annuar, shen yang lim, rahman jamal, nor azian abdul murad, norlinah mohamed ibrahim.  (2020).  glucocerebrosidase genetic variants in malays with early and late-onset parkinson's disease.  - neurology asia.  39-46. 

     

    alyssa zi-xin leong, pey yee lee, m. aiman mohtar, saiful effendi syafruddin, yuh-fen pung and teck yew low.  (2022).  short open reading frames (sorfs) and microproteins: an update on their identification and validation measures.  - journal of biomedical science.  1-15. 

     

    saroor a. patel, shoko hirosue, paulo rodrigues, erika vojtasova, emma k. richardson, jianfeng ge, saiful e. syafruddin, alyson speed, evangelia k. papachristou, david baker, david clarke, ludovic wesolowski, , jason s. carroll, sakari vanharanta.  (2022).  the renal lineage factor pax8 controls oncogenic signalling in kidney cancer.  - nature.  999-1006. 

     

    rashidah baharudin, muhiddin ishak, azliana muhamad yusof, sazuita saidin, saiful effendi syafruddin, wan fahmi wan mohamad nazarie, learn-han lee, nurul-syakima ab mutalib.  (2022).  epigenome-wide dna methylation profiling in colorectal cancer and normal adjacent colon using infinium human methylation 450k.  - diagnostics.  1-22. 

     

    nisa syakila a. rahman, syazalina zahari, saiful effendi syafruddin, mohd firdaus-raih, teck yew low, m. aiman mohtar.  (2022).  functions and mechanisms of protein disulfide isomerase family in cancer emergence.  - cell & bioscience.  1-19. 

     

    siti nur hasanah mohd yusuf, asmaa y. abuhamad, ling sheen, nurul nadia zamberi, mohamad aimanuddin mohtar, saiful effendi syafruddin.  (2022).  pdgfb paracrine signalling fuels growth promoting-mtorc1 hyperactivation in clear cell renal cell carcinoma (ccrcc).  - malaysian journal of medicine and health sciences.  46. 

     

    saiful effendi syafruddin, mohamad aimanuddin mohtar, tan shing cheng, nadiah abu, nor aidatulakma abdullah@muda, nurul syakima ab mutalib, chin siok fong, neoh hui min, rahman jamal, nor azian abdul murad.  (2019).  malaysian higher institution centres of excellence (hicoe) official compendium.  - 244. 

     

    nurainie sayutti, muhammad azrai abu, saiful effendi, mohd faizal ahmad.  (2022).  elucidating the gene expression of grem 1 in cumulus cells and its association with oocytes quality in predicting pregnancy outcomes among pcos women.  - gynecological endocrinology the 20th world congress.  1. 

     

    low teck yew;mohd firdaus bin mohd raih;saiful effendi bin syafruddin;mohamad aimanuddin bin mohtar;lee pey yee.  (2022).  elucidating the mechanism of secretion for human pro-metastatic agr2 protein.  -

     

    nurul nadia mohamad zamberi, asmaa y. abuhamad, teck yew low, m. aiman mohtar, and saiful effendi syafruddin.  (2022).  the epigenetic modulators brd4 and p300 support klf6 super enhancer activity in promoting renal tumorigenesis.  - 46th annual conference of the malaysian society for biochemistry and molecular biology 2022 (msbmb46).  1-7. 

     

    saiful effendi syafruddin.  (2022).  cellular and molecular biology of cancer: insights for early detection and therapeutics.  - 1-27. 

     

    mohamad aimanuddin mohtar, saiful effendi syafruddin.  (2022).  protein agr2: bio penanda baru untuk pengesanan awal kanser.  - impak: kluster kesihatan & perubatan termaju.  28-29.